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Unraveling the efficacy network: A network meta-analysis of adjuvant external beam radiation therapy methods after hepatectomy

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 205-214页

作者： Gao-Yuan Yang Zhi-Wei He yong-chang tang Feng Yuan Ming-Bo Cao Yu-Peng Ren Yu-Xuan Li Xiao-Rui Su Zhi-Cheng Yao Mei-Hai Deng Department of Hepatobiliary Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630Guangdong ProvinceChina Department of General Surgery Qilu HospitalShandong UniversityJinan 250012Shandong ProvinceChina Department of General Surgery The First Affiliated HospitalGuangzhou Medical UniversityGuangzhou 511436Guangdong ProvinceChina Department of Hepatobiliary and Pancreatic Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630Guangdong ProvinceChina

BACKGROUND Primary liver cancer is a malignant tumor with a high recurrence rate that significantly affects patient *** adjuvant external radiation therapy(RT)has been shown to effectively prevent recurrence after liver cancer ***,there are multiple RT techniques available,and the differ-ential effects of these techniques in preventing postoperative liver cancer re-currence require further *** To assess the advantages and disadvantages of various adjuvant external RT methods after liver resection based on overall survival(OS)and disease-free survival(DFS)and to determine the optimal *** This study involved network meta-analyses and followed the PRISMA *** data of qualified studies published before July 10,2023,were collected from PubMed,Embase,the Web of Science,and the Cochrane *** included relevant studies on postoperative external beam RT after liver resection that had OS and DFS as the primary *** magnitudes of the effects were determined using risk ratios with 95%confidential *** results were analyzed using R software and STATA *** A total of 12 studies,including 1265 patients with hepatocellular carcinoma(HCC)after liver resection,were included in this *** was no significant heterogeneity in the direct paired comparisons,and there were no significant differences in the inclusion or exclusion criteria,intervention measures,or outcome indicators,meeting the assumptions of heterogeneity and *** analysis revealed that patients who underwent stereotactic body radiotherapy(SBRT)after resection had longer OS than those who underwent intensity modulated radiotherapy(IMRT)or 3-dimensional conformal RT(3D-CRT).DFS analysis revealed that patients who underwent 3D-CRT after resection had the longest *** who underwent IMRT after resection had longer OS than those who underwent 3D-CRT and longer DFS than those who underwent ***

关键词： Primary liver cancer Hepatocellular carcinoma Network meta-analysis External beam radiation therapy Stereotactic body radiotherapy Intensity modulated radiotherapy

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Physics-Informed Neural Networks with Two Weighted Loss Function Methods for Interactions of Two-Dimensional Oceanic Internal Solitary Waves

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Journal of Systems Science & Complexity 2024年第2期37卷 545-566页

作者： SUN Junchao CHEN yong tang Xiaoyan School of Mathematical Sciences Key Laboratory of Mathematics and Engineering Applications(Ministry of Education)&Shanghai Key Laboratory of PMMPEast China Normal UniversityShanghai 200241China College of Mathematics and Systems Science Shandong University of Science and TechnologyQingdao 266590China

The multiple patterns of internal solitary wave interactions(ISWI)are a complex oceanic *** remote sensing techniques indirectly detect these ISWI,but do not provide information on their detailed structure and ***,the authors considered a three-layer fluid with shear flow and developed a(2+1)Kadomtsev-Petviashvili(KP)model that is capable of describing five types of oceanic ISWI,including O-type,P-type,TO-type,TP-type,and *** learning models,particularly physics-informed neural networks(PINN),are widely used in the field of fluids and internal solitary ***,the authors find that the amplitude of internal solitary waves is much smaller than the wavelength and the ISWI occur at relatively large spatial scales,and these characteristics lead to an imbalance in the loss function of the PINN *** solve this problem,the authors introduce two weighted loss function methods,the fixed weighing and the adaptive weighting methods,to improve the PINN *** successfully simulated the detailed structure and dynamics of ISWI,with simulation results corresponding to the satellite *** particular,the adaptive weighting method can automatically update the weights of different terms in the loss function and outperforms the fixed weighting method in terms of generalization ability.

关键词： Internal solitary wave interactions KP equation PINN method weighted loss function method

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Homological Transfer between Additive Categories and Higher Differential Additive Categories

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Acta Mathematica Sinica,English Series 2024年第5期40卷 1325-1344页

作者： Xi tang Zhao yong HUANG School of Science Guilin University of Aerospace TechnologyGuilin 541004P.R.China Department of Mathematics Nanjing UniversityNanjing 210093P.R.China

Given an additive category C and an integer n≥*** higher differential additive category consists of objects X in C equipped with an endomorphism ϵ_(X)satisfying ϵ_(X)^(n).Let R be a,finite-dimensional basic algebra over an algebraically closed field and T the augmenting functor from the category of finitely generated left R-modules to that of finitely generated left R/(t^(n))-*** is proved that a finitely generated left R-module M isτ-rigid(respectively,(support)τ-tilting,almost completeτ-tilting)if and only if so is T(M)as a left R[t]/(t^(n))-***,R isτm-selfinjective if and only if so is R[t]/(t^(n)).

关键词： Higher differential objects Wakamatsu tilting subcategories G_(ω)-projective modules sup-portτ-tilting modules τ_(m)-selfinjective algebras precluster tilting subcategories

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The unique spontaneous polarization property and application of ferroelectric materials in photocatalysis

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Nano Research 2024年第5期17卷 3571-3585页

作者： Jinghua An chang Xu Lu Li Bo tang College of Chemistry Chemical Engineering and Materials ScienceKey Laboratory of Molecular and Nano ProbesMinistry of EducationCollaborative Innovation Center of Functionalized Probes for Chemical Imaging in University of ShandongInstitute of Molecular and Nano ScienceShandong Normal UniversityJinan 250014China Laoshan Laboratory 168 Wenhai Middle RdAoshanwei JimoQingdao 266237China

The unique spontaneous polarization property of ferroelectric material makes it to be a special catalyst in *** spontaneous polarization property can induce the formation of built-in electric field,which can improve the separation of photoelectrons and holes to affect photocatalytic *** internal electric field induced by spontaneous polarization can be influenced by multiple factors such as the morphology,the concentration of defect,the type of doped heteroatoms,as well as the composition of ***,the preparation method,pretreating temperature,the strength of prepolarized external electric field of ferroelectric-based photocatalysts as well as the strength of external mechanical force or external magnetic field in photocatalytic reactions can influence the photocatalytic effectivity via influencing spontaneous polarization-induced internal electric ***,it is urgently to unveil the mystery of structure-activity relationships for ferroelectric materials-based photocatalysts,which is usually *** this in mind,this review was provided for the role of various complex influencing factors on ferroelectric materials-based photocatalysis based on the latest advancement in the fields of new energy development,environmental *** the beginning,the basic structure and properties of ferroelectric material are ***,popular synthesis methods of ferroelectric-based photocatalysts are *** that,two main mechanisms of ferroelectric photocatalysis are *** research progress of ferroelectric photocatalysis is then given emphatically according to the classification of photocatalytic ***,the problems existing nowadays and the challenges facing in the future on the application of ferroelectric materials-based photocatalysts are outlined in the summary and outlook section.

关键词： spontaneous polarization photocatalysis ferroelectric separation of electrons and holes

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Prefrontocortical Astrocytes Regulate Dominance Hierarchy in Male Mice

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Neuroscience Bulletin 2024年第3期40卷 415-417页

作者： yong tang Hai-Yan Yin Peter Illes School of Acupuncture and Tuina Chengdu University of Traditional Chinese MedicineChengdu 610075China International Joint Research Center on Purinergic Signaling Chengdu University of Traditional Chinese MedicineChengdu 610075China Rudolf Boehm Institute for Pharmacology and Toxicology University of Leipzig04107 LeipzigGermany

Social hierarchy is a general self-organizational scheme in animal societies in which each member achieves a certain status of domination or subordination when getting access to resources,with profound consequences for survival,health,reproductive success,and multiple behaviors[1,2].The prefrontal cortex(PFC)was recognized as a central regulator of neuronal circuits determining the formation of social hierarchy;brain areas upstream of the PFC convey information about social status,and downstream brain regions execute dominance behavior[3].Social deficits have been suggested to be due to an elevation of excitatory/inhibitory(E/l)balance within the mouse dorsomedial(dm)PFC[4].A compensatory increase of inhibitory cell excitability partially rescued social deficits caused by such a disturbance of E/l balance.

关键词： consequences hierarchy determining

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The relationship between interannual dry/wet changes and nomadic wars in the Hexi Corridor region of China during the period 241–1912 A.D.

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Science China Earth Sciences 2024年第6期67卷 1922-1931页

作者： Fei tang Zhilin SHI Qinhua TIAN Xiaogang DU yong ZHANG Key Laboratory of Land Surface Pattern and Simulation Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101China Institute of Dunhuang Studies Lanzhou UniversityLanzhou 730020China National Climate Center China Meteorological AdministrationBeijing 100081China Longchanghe Station Gansu Qilian Mountain National Nature ReserveZhangye 734400China University of Chinese Academy of Sciences Beijing 100049China

The link between climate and war has long been a topic of great scientific and social *** this study,we investigate the influence of climate on warfare in China’s Hexi Corridor region since 241 *** the superposed epoch analysis of tree-ring data and historical war data,we observe a notable correlation between interannual dry-wet variations and wars instigated by nomadic groups in the Hexi ***,this relationship is dynamic and influenced by the region’s relative *** periods in which the Hexi Corridor was ruled by multiple regimes,wars tended to follow dry climatic conditions,which may be due to the fact that unusual drought during these periods likely heightened competition for resources and ***,during times of regional unity,wars were more likely to occur when climatic conditions were wet because the expansion of rangelands and the accumulation of resources helped fuel the nomads’outward *** findings underscore the complexity of the relationship between war and climate *** gain a more comprehensive understanding of this relationship,continuous,high-resolution historical temperature and humidity datasets with broader and more uniform coverage are needed across multiple *** addition,collecting and examining disaggregated historical war data for regions with distinct characteristics is essential.

关键词： Drought Interannual dry and wet variations War The Hexi Corridor Tree ring Nomadic groups

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Immunobiology of COVID-19: Mechanistic and therapeutic insights from animal models

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Zoological Research 2024年第4期45卷 747-766页

作者： Hong-Yi Zheng Tian-Zhang Song yong-tang Zheng State Key Laboratory of Genetic Evolution&Animal Models KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common DiseasesCenter for Biosafety Mega-ScienceKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650223China National Resource Center for Non-Human Primates National Research Facility for Phenotypic&Genetic Analysis of Model Animals(Primate Facility)Kunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650107China

The distribution of the immune system throughout the body complicates in vitro assessments of coronavirus disease 2019(COVID-19)immunobiology,often resulting in a lack of reproducibility when extrapolated to the whole ***,developing animal models is imperative for a comprehensive understanding of the pathology and immunology of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)*** review summarizes current progress related to COVID-19 animal models,including non-human primates(NHPs),mice,and hamsters,with a focus on their roles in exploring the mechanisms of immunopathology,immune protection,and long-term effects of SARS-CoV-2 infection,as well as their application in immunoprevention and immunotherapy of SARS-CoV-2 *** among these animal models and their specific applications are also highlighted,as no single model can fully encapsulate all aspects of *** effectively address the challenges posed by COVID-19,it is essential to select appropriate animal models that can accurately replicate both fatal and non-fatal infections with varying courses and *** animal model libraries and associated research tools is key to resolving the global COVID-19 pandemic,serving as a robust resource for future emerging infectious diseases.

关键词： SARS-CoV-2 COVID-19 Animal models Infection immunology Immunotherapy

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Quantification of perfluorinated compounds in atmospheric particulate shows potential connection with environmental event

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Journal of Environmental Sciences 2024年第2期136卷 237-247页

作者： Hua tang Ying Wang Shengling Si Hongli Li David Da yong Chen National Institute of Metrology 18 BeisanhuandongluChaoyang DistrictBeijing 100029China School of Chemistry and Materials Science Nanjing Normal UniversityNanjing 210023China Si Chuan Zhong Ce Biao Wu Technology Co.Ltd. Sichuan 610052China Department of Chemistry University of British ColumbiaVancouver V6T 1Z1BCCanada

A method of quantification of perfluorinated compounds(PFCs)from atmospheric particulate matter(APM)is described.A single step pretreatment method,selective pressurized liquid extraction(SPLE),was developed to reduce the high matrix background and avoid contamination from commonly used multiple sample pretreatment *** effective sorbent was selected to purify the PFCs during SPLE,followed by liquid chromatography-tandem mass spectrometry(LC–MS/MS),for quantification of *** affecting the SPLE efficiency,including temperature,static extraction time,and number of extraction cycles used,were *** optimum conditions were found to be 120℃,10 min,and 3 cycles,***-MS/MS method was developed to obtain the optimal sensitivity specific to *** method detection limits(MDLs)were 0.006 to 0.48 ng/g for the PFCs studied and the linear response range was from 0.1 to 100 ng/*** ensure accurate values were obtained,each step of the experiment was evaluated and controlled to prevent *** optimized method was tested by performing spiking experiments in natural particulate matter matrices and good rates of recovery and reproducibility were obtained for all target ***,the method was successfully used to measure 16 PFCs in the APM samples collected in Beijing over five years from 2015 to *** is observed that some PFCs follow the trend of total PFC changes,and can be attributed to the environment influencing events and policy enforcement,while others don't seem to change as much with time of the year or from year to year.

关键词： Selective pressurized liquid extraction Liquid chromatography-mass spectrometry Perfluorinated compounds Atmospheric particulate matter Pollution control

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Cross-linkedα-amylase aggregates on Fe3O4 magnetic nanoparticles modified with polydopamine/polyethyleneimine for efficient hydrolysis of starch

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Particuology 2024年第7期90卷 98-105页

作者： Jiandong Cui Xiuming tang Qingqing Ma Yuyan chang Qunli Zhang Shiru Jia State Key Laboratory of Food Nutrition and Safety Laboratory of Industrial Fermentation MicrobiologyMinistry of EducationTianjin University of Science and TechnologyTianjin 300457China Key Laboratory of Biomass Chemical Engineering of Ministry of Education Zhejiang UniversityHangzhou 310027China

In this workα-amylase was immobilized on magnetic Fe3O4 nanoparticles with polyethylenimine(PEI)/polydopamine(PDA)coating or 3-aminopropyl triethoxysilane(APTES)for the first time via adsorption–precipitation–*** with the freeα-amylase,the resultant magnetic cross-linkedα-amylase aggregates(PEI/PDA-M-CLEAs and N-M-CLEAs)exhibited excellent thermal and storage stability as well as pH *** storage at 25°C for 60 days,freeα-amylase only retained 60%of its initial activity,while PEI/PDA-M-CLEAs and N-M-CLEAs retained 80%and 78%of their initial activities,***,N-M-CLEAs and PEI/PDA-M-CLEAs showed good *** 6 repeated uses,PEI/PDA-M-CLEAs and N-M-CLEAs still maintained 65%and 62%of their initial activities,***,PEI/PDA-M-CLEAs and N-M-CLEAs exhibited higher starch hydrolysis efficiency than freeα-*** maximum dextrose equivalent(DE)values of starch hydrolysis by PEI/PDA-M-CLEAs and N-M-CLEAs reached 29.24%and 28.79%within 90 min,***,the maximum DE values of starch hydrolysis by the freeα-amylase was only 27.89%even in 150 *** magnetic cross-linkedα-amylase aggregates could be introduced as effective biocatalyst for industrial applications in production of maltose syrups.

关键词： α-amylase Magnetic nanoparticles Functional modification Magnetic cross-linked enzyme aggregates Hydrolysis of starch

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Environment-adaptive phase-separation-porous fluorofilm for highperformance passive radiation cooling

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Nano Research 2024年第6期17卷 5636-5644页

作者： Weiming tang yong Li Xue Meng Shutao Wang Ziguang Zhao School of Future Technology University of Chinese Academy of SciencesBeijing 100049China CAS Key Laboratory of Bio-inspired Materials and Interfacial Science Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China CAS Key Laboratory of Cryogenics Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China

Passive radiative cooling is widely recognized as an environmentally sustainable method for achieving significant cooling ***,the mechanical properties and environmental adaptability of current radiative cooling materials are not sufficient to maintain high cooling performance in external *** we reported an environment-adaptive phase-separation-porous fluorofilm for high-performance passive radiation *** to the homogenous fluoro-porous network with limited scattering efficiencies,we modulated the porous structure of the fluorofilm to achieve a strong emissivity of 95.2%(8-13μm)and a high reflectivity of 97.1%(0.3-2.5μm).The fluorofilm demonstrates a temperature drop of 10.5°C and an average cooling power of 81 W·m^(−2)under a sunlight power of 770 W·m^(−2).The high mechanical performance and environmental adaptability of fluorofilms are also *** its significant radiative cooling capability and robust environmental adaptability,the fluorofilm is expected to have a promising future in radiative temperature regulation.

关键词： fluorofilm passive radiation cooling porous optimization thermal regulation

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