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A two-step energy injection explanation for the rebrightenings of the multi-band afterglow of GRB 081029

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Research in Astronomy and Astrophysics 2013年第6期13卷 662-670页

作者： yong-bo yu yong-Feng Huang Department of Astronomy Nanjing University Key Laboratory of Modern Astronomy and Astrophysics (Nanjing University) Ministry of Education

The afterglow of GRB 081029 showed unusual behavior, with a signifi- cant rebrightening being observed at the optical wavelength at about 3000 s after the burst. One possible explanation is that the rebrightening resulted from an energy in- jection. Here we present a detailed numerical study of the energy injection process and interpret the X-ray and optical afterglow light curves of GRB 081029. In our model, we have assumed two periods of energy injection, each with a constant injec- tion power. One injection starts at 2.8 × 10^3 s and lasts for about 2500 s, with a power of 7.0 × 10^47 erg s-1. This energy injection mainly accounts for the rapid rebrighten- ing at about 3000 s. The other injection starts at 8.0 × 10^3 s and lasts for about 5000 s. The injection power is 3.5 × 10^47 erg s-1. This energy injection can help to explain the slight rebrightening at about 10 000 s. It is shown that the observed optical after- glow, especially the marked rebrightening at about 3000 s, can be reproduced well. In the X-ray band, the predicted amplitude of the rebrightening is much shallower, which is also consistent with the observed X-ray afterglow light curve. It is argued that the two periods of energy injection can be produced by clumpy materials falling onto the central compact object of the burster, which leads to an enhancement of accretion and gives rise to a strong temporary outflow.

关键词： gamma-rays: bursts -- ISM: jets and outflows -- individual:GRB 081029

Research on tune feedback of the Hefei Light SourceⅡbased on machine learning

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Nuclear Science and Techniques 2022年第3期33卷 45-52页

作者： yong-bo yu Gong-Fa Liu Wei Xu Chuan Li Wei-Min Li Ke Xuan National Synchrotron Radiation Laboratory University of Science and Technology of ChinaHefei 230029AnhuiChina

The theory of tune feedback correction and the principle of a feedback algorithm based on machine learning are introduced,with a focus on the application of lasso regression for tune feedback *** verification and online feedback correction results are *** results show that,after applying machine learning,the feedback accuracy of the tune feedback system was higher,and the betatron tune stability was further improved.

关键词： Storage ring Tune feedback Machine learning Lasso regression

Changes in percentage of lymphocyte subsets after ^(131)I treatment in patients with differentiated thyroid cancer

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Nuclear Science and Techniques 2005年第4期16卷 214-216页

作者： LUO Quan-yong CHEN Li-bo yu yong-Li LU Han-Kui ZHU Rui-Sen Department of Nuclear Medicine Shanghai Sixth People＇s Hospital. Shanghai Jiaotong University Shanghai 200233

To monitor the extent and the duration of lymphocyte subset changes in patients with thyroid carcinoma undergoing therapeutic 131I administration, the percentage of lymphocyte subsets were serially analyzed before and after 131I treatment. In patients who received 1850 MBq of 131I for ablation of thyroid remnants, only for NK cells and B cells showed a significant reduction. In patients received 3700 MBq of 131I for treatment of local lymph node me-tastases, NK cells, B cells and CD4+ were found decreased. In patients received 7400 MBq of 131I for treatment of distant metastases, NK cells, B cells and CD4+ and CD8+ were all affected. However, there is no significant reduc-tion compared to the baseline in the percentage of all lymphocyte subsets three months after 131I treatment. The re-sults show that the sensitivity of lymphocytes to 131I internal radiation depends upon lymphocyte phenotype and 131I activity. The immunosuppression effects are temporary and reversible.

关键词：淋巴细胞 ^131I 甲状腺癌症放射性疗法抑制免抑反应

The relationship between human papillomavirus and penile cancer over the past decade:a systematic review and meta-analysis

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Asian Journal of Andrology 2019年第4期21卷 375-380页

作者： yong-bo yu yong-Hua Wang Xue-Cheng Yang Yang Zhao Mei-Lan Wang Ye Liang Hai-Tao Niu Department of Urology Affiliated Hospital of Qingdao University Qingdao 266003 China The Nursing Department Qingdao University Qingdao 266021 China

Human papillomavirus (HPV) infection appears to play an important role in the development of penile cancer (PeCa), but their relationship remains unclear. Therefore, we performed a systematic review and meta-analysis to elucidate their relationship. We systematically searched Embase, PubMed, Cochrane Library, and Web of Science for case-control studies and cross-sectional studies using polymerase chain reaction (PCR) tech no logy on formali n?fixed paraffi n-embedded (FFPE) or pa raff i n-embedded (PE) PeCa tissues to detect HPV (published between January 1, 2007, and December 29, 2017;no language restrictions). Twenty-two studies were identified, and 1664 cases were available for analysis. The combined HPV infectious risk of PeCa is 51.0%(95% confidence interval [Cl]: 43.0%-60.0%). The three most common subtypes of HPV were HPV16 (28.5%), HPV18 (2.3%), and HPV6 (2.3%). The virus was relevantly associated with basaloid (85.5%, 95% Cl: 77.2%-93.8%) and warty (50.0%, 95% Cl: 35.2%-64.8%) carcinomas. The invasiveness of PeCa was not associated with HPV (X^2 = 0.181, df = 1, P< 0.671). HPV infection in PeCa tended to be moderately differentiated (54.4%, 95% Cl: 47.7%-61.1%). This study found that almost half of PeCa patients are associated with HPV. The most comm only associated geno type is HPV16, but several other geno types were also detected. In addition to types 6 and 11, other single low-risk HPV infections have been found to contribute to PeCa to a lesser degree. HPVpositive tumors tend to exhibit warty and/or basaloid features, corresponding to a moderate histological grade. The role of HPV in PeCa should be revisited to provide evidenee for the development of PeCa in the presenee of HPV infection.

关键词： human papillomavirus penile cancer systematic review and meta-analysis

Calculation of valence band structures of InAs/GaAs quantum ring and quantum dot:using numerical Fourier transform method

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The Journal of China Universities of Posts and Telecommunications 2010年第1期17卷 106-110页

作者： JIA bo-yong,yu Zhong-yuan,LIU yu-min,TIAN Hong-da Key Laboratory of Information Photonics and Optical Communications,Ministry of Education,Beijing University of Posts and Telecommunications,Beijing 100876,China Key Laboratory of Information Photonics and Optical Communications Ministry of Education Beijing University of Posts and Telecommunications Beijing 100876 China

This article puts forward a new method in calculating the band structures of low-dimensional semiconductor structures. In this study, the valence band structures of InAs/GaAs quantum ring and lens-shaped quantum dot are calculated with four-band model, in the framework of effective-mass envelope function theory. To determine the Hamiltonian matrix elements, this article develops the numerical Fourier transform method instead of the widely used analytical integral method. The valence band mixing is considered. The hole energy levels change dramatically with the geometrical parameters of the quantum ring and quantum dot. It is demonstrated that numerical Fourier transform method can be adopted in low-dimensional structures with any shape. The results of Fourier transform method are consistent with the ones of analytical integral in literature; and they are helpful for studying and fabricating optoelectronic devices.

关键词： valence band structures quantum ring quantum dot numerical Fourier transform

Effects of nocturnal snacks on body composition in patients with liver cirrhosis

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World Journal of Hepatology 2024年第12期16卷 1458-1467页

作者： yong-bo yu Xiu-Juan Fu Guo-Fen Xu Ling-yun Niu Ruo-Nan Duan Jia Yao Ning-Hui Zhao Department of Neurology Third Hospital of Shanxi Medical UniversityShanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalTaiyuan 030032Shanxi ProvinceChina Department of Gastroenterology Third Hospital of Shanxi Medical UniversityShanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalTaiyuan 030032Shanxi ProvinceChina Department of Nutrition Third Hospital of Shanxi Medical UniversityShanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalTaiyuan 030032Shanxi ProvinceChina

BACKGROUND Patients with liver cirrhosis are universally malnourished and the nocturnal snacks intervention is the currently recommended nutritional intervention for patients with liver *** composition is an important indicator for the assessment of nutritional *** investigated the effects of nocturnal snacks(200 kcal/day)for 3 months on body composition in patients with liver *** patients with liver cirrhosis and 30 healthy controls were enrolled,and differences in body composition were detected using Inbody 720,a body composition *** patients were further randomized into a normal diet group(three meals a day)and nocturnal snacks group(three meals a day+nocturnal snacks).The effect of nocturnal snacks on the body composition of patients with cirrhosis was assessed after 3 months of *** body fat mass(BFM),skeletal muscle mass(SMM),fat free mass,visceral fat area(VFA),and body cell mass(BCM)were significantly lower in the liver cirrhosis patients than in the healthy *** 3 months’intervention,BFM,VFA and BCM were significantly higher in the nocturnal snacks group than in the normal diet group,with no significant differences in total caloric intake and daily ***,there was no significant difference in SMM between the nocturnal snacks and normal diet *** Long-term nocturnal snacks may improve body composition indices such as BFM,VFA and BCM in patients with ***,the improvement was minor for SMM.

关键词： Liver cirrhosis Malnutrition Nocturnal snacks body composition Nutritional intervention

Effects of cell membrane phospholipid level and protein kinase C isoenzyme expression on hepatic metastasis of colorectal carcinoma

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Hepatobiliary & Pancreatic Diseases International 2004年第3期3卷 411-416页

作者： Shi-yong Li, bo yu, Ping An, Zhen-Jia Liang, Shu-Jun yuan and Hui-yun Cai Department of General Surgery, Beijing Military Ge-neral Hospital, Beijing 100700, China Department of General Surgery Beijing Military General Hospital Beijing 100700 China. shiyongli@***

BACKGROUND: The molecular mechanism of hepaticmetastasis of colorectal cancer is not well understood. Theaim of this study was to assess the relations between phos-pholipid contents of cellular membrane and isoenzyme ex-pression of protein kinase C (PKC) and their effects on he-patic metastasis of colorectal ***: High performance liquid chromatography wasused to detect contents of cell membrane phospholipids:phosphatidylinosital (PI), phosphatidylserine (PS), phos-phatidylethanolamine (PE) and phosphatidylcholine (PC)in primary foci, paratumor mucosa and hepatic metastaticfoci in patients with colorectal carcinoma. The mRNA ex-pression levels of PKC-α, -δ, -ε, -λ, -ξ isoenzymeswere detected with the QRT-PCR ***: The levels of PI, PC and PE in primary foci andhepatic metastatic foci were higher than those in paratumormucosa. The level of PE in hepatic metastatic foci wasmuch higher than that in primary foci (t =98.88, P 0.05). The expression levels of -δ, -ε,-λ, -ξ were enhanced in primary foci and hepatic metasta-tic foci, but the level of PKC-α in primary foci was de-creased as compared with that in paratumor mucosa. Thelevels of PKC-δ, -ε, -λ, -ξ in hepatic metastatic foci werehigher than those in primary foci. A positive correlationwas observed between the expression levels of PI, PC andand also between those of PE and PKC-δ, -ε, -λ,-ξ. However, there was a close negative correlation be-tween PE and PKC-α.CONCLUSION: Increased levels of PI and PC and de-creased ratio of PKC-α to are related to colorectalcancer genesis. Increased levels of PE, increased expressionof PKC-δ, -ε, -λ, -ξ isoenzymes and decreased level ofPKC-α are related to hepatic metastasis in colorectal carci-noma.

关键词： colorectal carcinoma membrane phospholipid protein kinase C hepatic metastasis

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面向车联网高效安全的消息认证方案

通信学报 2016年第11期37卷 1-10页

作者：吴黎兵谢永张宇波武汉大学计算机学院湖北武汉430072 景德镇陶瓷大学信息工程学院江西景德镇333403 武汉大学软件工程国家重点实验室湖北武汉430072

提出一种新型高效的基于身份的消息认证方案,该方案采用椭圆曲线密码构建了轻量级的安全认证协议,无需双线性对运算,降低了签名与认证过程的运算复杂性,同时提供了条件隐私保护的功能,安全分析验证了该方案可以满足VANET的安全需求。性... 详细信息

提出一种新型高效的基于身份的消息认证方案,该方案采用椭圆曲线密码构建了轻量级的安全认证协议,无需双线性对运算,降低了签名与认证过程的运算复杂性,同时提供了条件隐私保护的功能,安全分析验证了该方案可以满足VANET的安全需求。性能分析表明,与最近的相关方案相比,该方案不仅减少了签名与验证的计算开销,同时也降低了通信开销。

关键词：车联网认证方案椭圆曲线密码效率条件隐私保护

Influence of FasL gene expression on hepatic metastasis of colorectal carcinoma

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Hepatobiliary & Pancreatic Diseases International 2004年第2期3卷 226-229页

作者： Shi-yong Li, bo yu, Ping An, Jia-Chen Wei, Fu-Yi Zuo and Hui-yun Cai Beijing, China Department of General Surgery, Beijing Military Commend General Hospital, Beijing 100700, China Department of General Surgery Beijing Military Commend General Hospital Beijing 100700 China. shiyongli@cnope ***

BACKGROUND: FasL expression was reported to be asso- ciated with hepatic metastasis of colorectal cancer. The aim of this study was to study FasL gene expression in colorectal carcinoma and its influences on biological behavior and he- patic metastasis of colorectal carcinoma. METHODS: FasL gene expressions were examined with re- verse transcriptase-polymerase chain reaction (RT-PCR) in the primary focus of colorectal carcinoma, adjacent can- cerous mucosae, and metastasized liver focus from colorec- tal cancer. HR-8348 cells of human rectal cancer cell line were transfected with FasL cDNA. Cell growth suppression rate and response to 5-FU and carboplatin were observed and analyzed with the MTT method. RESULTS: FasL gene expression was detected in the prima- ry focus of colorectal cancer ( n = 58), adjacent cancerous mucosae ( n = 58), and metastasized hepatic tumor tissues (n =28). The positive rate of FasL expression was 24% (14/ 58), 8% (5/58), and 100% (58/58) in the primary focus, adjacent cancerous mucosae and metastasized hepatic tumor tissues respectively. FasL expression rate in the me- tastasized hepatic tumor tissues was higher than that in the primary focus (χ2 = 43.49, Pboplatin was added, there was a significant difference in growth suppression rate between FasL positive and controlled cancer cells (t=9.02, t = 11.93, P<0.01). Under the same concentration of chemotherapeutic agents, the survival rate of FasL positive HR-8348 cells was higher than that of controlled cells. CONCLUSIONS: FasL positive cancer cells are powerfullyresistant to chemotherapeutic agents. The expression of the FasL gene in colorectal cancer cells is r

关键词： colorectal tumor gene expression tumor metastasis gene FasL