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Assessing the corrosion protection property of coatings loaded with corrosion inhibitors using the real-time atmospheric corrosion monitoring technique

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 119-126页

作者： Xiaoxue wang Lulu jin jinke wang Rongqiao wang Xiuchun Liu Kai Gao jingli Sun yong Yuan Lingwei Ma Hongchang Qian Dawei Zhang School of Energy and Power Engineering Beihang UniversityBeijing 100191China Beijing Institute of Space Long March Vehicle Beijing 100076China National Materials Corrosion and Protection Data Center University of Science and Technology BeijingBeijing 100083China Institute of Materials Intelligent Technology Liaoning Academy of MaterialsShenyang 110004China Shanghai Spaceflight Precision Machinery Institute Shanghai 201600China

The atmospheric corrosion monitoring(ACM)technique has been widely employed to track the real-time corrosion behavior of metal ***,limited studies have applied ACM to the corrosion protection properties of organic *** study compared a bare epoxy coating with one containing zinc phosphate corrosion inhibitors,both applied on ACM sensors,to observe their corrosion protection properties over *** with artificial damage via scratches were exposed to immersion and alternating dry and wet environments,which allowed for monitoring galvanic corrosion currents in *** the corrosion tests,the ACM currents of the zinc phosphate/epoxy coating were considerably lower than those of the blank epoxy *** trend in ACM current variations closely matched the results obtained from regular electrochemical tests and surface *** alignment highlights the potential of the ACM technique in evaluating the corrosion protection capabilities of organic *** with the blank epoxy coating,the zinc phosphate/epoxy coating showed much-decreased ACM current values that confirmed the effective inhibition of zinc phosphate against steel corrosion beneath the damaged coating.

关键词： atmospheric corrosion monitoring technology corrosion inhibitor coating carbon steel corrosion protection

On-chip optical interconnect using visible light

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Frontiers of Information Technology & Electronic Engineering 2017年第9期18卷 1288-1294页

作者： Wei CAI Bing-cheng ZHU Xu-min GAO yong-chao YANG Jia-lei YUAN Gui-xia ZHU yong-jin wang Peter GRUNBERG Peter Griinberg Research Center Nanjing University of Posts and Telecommunications Nanjing 210003 China School of Computer Engineering Nanjing Institute of Technology Nanjing 211167 China

We propose and fabricate a monolithic optical interconnect on a GaN-on-silicon platform using a wafer-level technique. Because the InGaN/GaN mukiple-quantum-well diodes （MQWDs） can achieve light emission and detection simultaneously, the emitter and collector sharing identical MQW structure are produced using the same process. Suspended waveguides interconnect the emitter with the collector to form in-plane light coupling. Monolithic optical interconnect chip integrates the emitter, waveguide, base, and collector into a multi-component system with a common base. Output states superposition and 1 × 2 in-piane light communication are experimentally demonstrated. The proposed monolithic optical interconnect opens a promising way toward the diverse applications from in-plane visible light communication to light-induced imaging, and optical sensing. artificial synaptic devices, intelligent display, on-chip

关键词： Homogeneous integration Multiple-quantum-well diode Visible light interconnection Coexistence oflight emission and photodetection

A New Shaping Model for Green Ceramic Balls

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厦门大学学报（自然科学版） 2002年第S1期41卷 35-36页

作者： REN Cheng-zu, WU Zhen-yong, jin Xin-ming, wang Chun-jie, XU Qiang (Institute of Mechanical Engineering, Tianjin University, Tianjin 300072, China)

The shaping quality of green ceramic balls is directly related to the efficiency and cost of later machining for the ceramic balls. Until now the shaping for green ceramic balls is still conducted by handwork. In this paper, a new shaping model for green ceramic balls was designed. In the new model, two grinding wheels with the same generator line as circular arc are mounted on symmetry, and their axes are parallel. The green ball can be put in the enveloping space formed by the two grinding wheels. The radius of generator line must be equal to or slightly greater than the final radius of the green balls, which can ensure that an ideal sphere can be enveloped by the generator of grinding wheel as grinding the green body surface with the wheels. One of the two wheels rotates in upward direction at high speed v 1, conversely, the other wheel rotates in downward direction at low speed v 2, and a cluster of compressed air is exerted on the green ball above for canceling out the force acting upon the green ball created by the action of the grinding wheel revolving at high speed and avoiding that the green ball jumps off its station. Because of the randomness of the distributions of abrasive grains on the surface of grinding wheels, the size and shape of the abrasive grains, and the posture of green body when falling into the grinding space, the values and directions of the resultant forces and torques exerted on the body, caused by the tow wheels, are random, the rotation of green body is irregular under the actions of the compressed air and the wheels. The irregularity of rotation can ensure an ideal sphere in theory. Experiment researches indicate that the new shaping model can improve the spherical deviations and the size distribution of the green ceramic balls, raise the production, and reduce the costs. The spherical deviations can be improved to 0.04 mm easily. It can be observed by SEM that there is no crack in the surface of sintered ceramic balls shaped with the

关键词： ceramic balls green shaping spherical deviation

Water Resources Operation and Management Model and Its Simulation Process Research

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Journal of Systems Science and Systems Engineering 2001年第3期13卷 328-338页

作者： MA Bin, XIE Jian-cang,\ ZHANG yong-jin,\ SUN Yi,\ wang Ni Xi′an University of Technology, Xi′an 710048, China Xi′an University of Technology Xi′an 710048 China

Based on the status quantity of water resources in Xi′an region, a commentary on many math models is given for water resources operation and management, and the visual model is provided to solve practical problems. In this model, the information for decision is visible in GIS (Geographic Information Systems) and topological figures. With object orientation methods, the objects are described in proprieties, methods, relations and time periods. The simulation process of the model is developed with Delphi and MapInfo, and the real decision scheme could be examined and practice decision process can be simulated from which. Decision analysis conducted from visual conditions is believable. The exploration to visual model is a beginning of practice research, much more study of which still needs to do.

关键词： water resources operation and management visual decision simulation process object orientation method topological model

Callus induction and plant regeneration from mature bluegrass (Poa pratensis L.) seeds

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Forestry Studies in China 2006年第4期8卷 25-29页

作者： Sun Bi-po Zhang Wan-jun Dong Jiang-li jin yong-sheng wang Tao State Key Laboratory of Agro-biotechnology China Agricultural University Beijing 100094 P. R. China

A protocol was discussed for high efficient plant regeneration from seven bluegrass （Poa pratensis L.） cultivars via an in- direct callus induction and somatic embryogenesis method. Mature seeds were used as explants for callus initiation. Callus induction and proliferation efficiencies were investigated on NB, modified MS （MMS） and MS media, supplemented with 2.0 mg·L^-1 2,4-dichlorophenoxyacetic acid （2,4-D）. The MMS medium performed best. Based on the MMS medium, direct and indirect callus induction effects of bluegrass from mature seeds were compared at the range of 1-5 mg·L^-1 2,4-D contained in the medium. Under the direct callus induction method, the most suitable 2,4-D concentrations varied among cultivars. Under the indirect callus induction method, a significantly high callus induction frequency （93.33%-98.33%） was obtained and there were barely any statistically sig- nificant differences among the tested genetically diverse cultivars. Somatic embryos were promoted on the MMS medium supple- mented with 3 mg·L^-1 2,4-D, 0.1 mg·L^-1 kinetin and 0.8 mg·L^-1 CuSO4. Embryogenetic calli developed into plantlets on the MMS medium containing different concentrations of thidiazuron （TDZ）, and the differentiation frequencies varied in the range from 20.15% to 77.65%. The 0.25 mg·L^-1 TDZ was generally the most suitable concentration for the tested cultivars.

关键词： mature seeds bluegrass (Poa pratensis L.) callus tissues culture regeneration

Trinuclear gold-catalyzed site-selective alkylation of peptides

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Science China Chemistry 2025年第1期68卷 249-256页

作者： Qing-Yun Fang Chengyihan Gu Yinghan Chen Wencheng Yan yong Liang Weipeng Li Chengjian Zhu Jie Han jin Xie State Key Laboratory of Coordination Chemistry Jiangsu Key Laboratory of Advanced Organic Materials Chemistry and Biomedicine Innovation Center (Chem BIC) School of Chemistry and Chemical Engineering Nanjing University Green Catalysis Center College of Chemistry Zhengzhou University State Key Laboratory of Natural Medicines China Pharmaceutical University

Selective modification of peptides has always been a challenging issue. The selective alkylation of peptides can alter the biological activity and physical properties of molecules, and it has gained significant research interest. We herein disclose an intriguing gold-catalyzed alkylation of peptides using bench-stable unactivated alkyl bromides under photoredox catalysis. A wide range of structurally diverse primary, secondary and tertiary alkyl bromides serve as effective coupling partners to precisely connect with the α-C(sp3)–H in glycine residue of peptides. This protocol demonstrates an exceptionally broad scope for alkyl halides and excellent tolerance for a wide range of useful functional groups. A series of relay transformations to construct cyclic peptides, to proceed click reaction and to realize peptide fluorescence labeling further enhance its synthetic practicality. In addition, mechanistic studies and density functional theory(DFT) calculations reveal an inner-sphere and subsequent outersphere single electron transfer(SET) mechanism.

关键词： gold catalysis peptide alkylation C-C coupling radical

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Enhancing m^(6)A modification in the motor cortex facilitates corticospinal tract remodeling after spinal cord injury

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Neural Regeneration Research 2025年第6期20卷 1749-1763页

作者： Tian Qin Yuxin jin Yiming Qin Feifei Yuan Hongbin Lu Jianzhong Hu yong Cao Chengjun Li Department of Spine Surgery and Orthopedics Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Key Laboratory of Organ Injury Aging and Regenerative Medicine of Hunan ProvinceChangshaHunan ProvinceChina National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Department of Sports Medicine Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina

Spinal cord injury typically causes corticospinal tract disruption. Although the disrupted corticospinal tract can self-regenerate to a certain degree, the underlying mechanism of this process is still unclear. N6-methyladenosine(m^(6)A) modifications are the most common form of epigenetic regulation at the RNA level and play an essential role in biological processes. However, whether m^(6)A modifications participate in corticospinal tract regeneration after spinal cord injury remains unknown. We found that expression of methyltransferase 14 protein(METTL14) in the locomotor cortex was high after spinal cord injury and accompanied by elevated m^(6)A levels. Knockdown of Mettl14 in the locomotor cortex was not favorable for corticospinal tract regeneration and neurological recovery after spinal cord injury. Through bioinformatics analysis and methylated RNA immunoprecipitation-quantitative polymerase chain reaction, we found that METTL14 regulated Trib2 expression in an m^(6)A-regulated manner, thereby activating the mitogen-activated protein kinase pathway and promoting corticospinal tract regeneration. Finally, we administered syringin, a stabilizer of METTL14, using molecular docking. Results confirmed that syringin can promote corticospinal tract regeneration and facilitate neurological recovery by stabilizing METTL14. Findings from this study reveal that m^(6)A modification is involved in the regulation of corticospinal tract regeneration after spinal cord injury.

关键词： corticospinal tract remodeling epigenetic regulations locomotor cortex m^(6)A modification methyltransferase 14 protein(METTL14) mitogen-activated protein kinase neural regeneration spinal cord injury syringin TRIB2

Treatment with epigenetic factors of 5-aza-deoxycytidine and TSA sensitize neurotoxic effects of neurotoxins on doparminergic neurons

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Treatment with epigenetic factors of 5-aza-deoxycytidine and...

Increased circulating of myeloid-derived suppressor cells in myelodysplastic syndrome

中国神经科学学会第四次会员代表大会暨第七届全国学术会议

作者： yong wang,jin HU,Xiao-Min wang Key Laboratory for Neurodegenerative Disease,Ministry of Education of China Department of Physiology,Capital Medical University,Beijing 100069,China

Parkinson’s disease(PD) is a progressive neurodegenerative disease related to age,which primarily results from the death of dopaminergic neurons in the substantia *** evidences have approved epigenetic factors play important roles in the aging and disorder of human being and animals.5-aza-deoxycytidine(5-aza-dC) as DNA methylation inhibitor and trichostatin A(TSA) as histone acetylation inhibitor were used to induce status alteration of DNA methylation and histone acetylation in *** our studies,SH-SY5Y cells(human),N27 cells(rat) and MN9D(mouse) were used as dopaminergic cell models that we treated with 5-aza-dC or *** results showed that treatment with 5-aza-dC or TSA led to decreased cell viability and apoptosis in dopaminergic *** of 5-aza-dC and typical neurotoxins in PD, ***,6-OHDA or rotenone,resulted in stronger damages in dopaminergic cells than either of *** results suggested that epigenetics might play roles in in pathogenesis of Parkinson’s disease through association with cell death of dopaminergic neurons.

关键词： Parkinson’s disease epigenetic doparminergic neuron sensitize neurotoxins

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Chinese Medical Journal 2013年第13期126卷 2582-2584页

作者： JIANG Hui-juan FU Rong wang Hua-quan LI Li-juan QU Wen LIANG yong wang Guo-jin wang Xiao-ming WU Yu-hong LIU Hong SONG Jia GUAN jing X1NG Li-min RUAN Er-bao SHAO Zong-hong Department of Hematology General Hospital of Tianjin Medical University Tianjin 300052 China

Myelodysplastic syndrome （MDS） is a group of clonal .hematopoietic stem cell disorders, characterizedby varying degrees ot peripheral cytopema caused by ineffective dysplasia of the myeloid lineages. MDS also has a high risk of progression to acute myeloid leukemia. But the role of immune abnormalities in the pathogenesis of MDS is still not clear. Myeloid-derived suppressor cells （MDSCs） constitute a heterogeneous population of immature cells derived from the bone marrow. In the recent years, MDSCs were reported to play an important role in suppressing lymphocytes in tumor-bearing animal models and cancer patients. This could be one of the mechanisms on tumor immune evasion, which aggravates the development and growth of tumors. In a mice model, MDSCs are characterized by co- expression of GR1 and CDllb. In humans, the phenotype of MDSCs was accepted as Lin- HLA-DR- CD33＋.l In the present study, we investigated the level of circulating MDSCs （Lin- HLA-DR- CD33＋） in patients with MDS and evaluated the association between MDSCs and malignancy in MDS. METHODS Patients Thirty-five patients with MDS （24 men and 11 women, median age 59 years （age range 21-83）, including refractory anemia （n=3）; refractory anemia with ringed sideroblasts （n=3）; refractory cytopenia with multilineage dysplasia （n=9）; refractory anemia with excess blast-I （n=4）; refractory anemia with excess blast-II （n=16））, and without other systemic diseases, were enrolled in the present study. All the patients underwent diagnosis in the Department of Hematology, General Hospital of Tianjin Medical University from March 2011 to April 2012, according to the diagnostic criteria of MDS proposed between 2007 and 2008. After treatment for three months, 14 MDS patients were investigated again for their MDSCs changes. Twenty normal healthy individuals were selected as controls （9 men and 11 women, median age 34 years （age range 26-82））. The study was approved by the Ethics Committee of Tianjin Medical Universit

关键词： myeloid-derived suppressor cells myelodysplastic syndrome CD34+ cells