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Effectiveness of simulation-based learning regarding management of post-COVID complications in terms of knowledge,clinical decision-making ability,and self-efficacy among nursing students:A quasi-experimental study

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Journal of Acute Disease 2023年第3期12卷 96-101页

作者： Thakur Malvika Eenu Kumar yogesh Sarin Jyoti Nitesh Kumawat Shatrughan Pareek Department of Medical Surgical Nursing College of NursingMaharishi Markandeshwar(Deemed to be University)MullanaAmbalaIndia Department of Community Health Nursing College of NursingMaharishi Markandeshwar(Deemed to be University)MullanaAmbalaIndia College of Nursing Maharishi Markandeshwar(Deemed to be University)MullanaAmbalaIndia AIIMS JodhpurRajasthanIndia Indian Railway Health Services BikanerRajasthanIndia

Objective:To assess the effectiveness of simulation-based learning regarding the management of post-COVID complications in terms of knowledge,clinical decision-making ability,and self-efficacy among nursing ***:This was a quasi-experimental study conducted among 1152nd-year nursing *** participants were selected by a simple random sampling *** participants were divided into an experimental(n=56)and a comparison group(n=59)by a random table *** were analyzed using descriptive and inferential statistics with SPSS version ***:There were significant differences in mean post-test knowledge scores(P=0.03)and mean post-test self-efficacy scores(P=0.001)between the experimental and the comparison groups while the difference in mean post-test clinical decision-making ability scores between the two groups was non-significant(P=0.07).A positive correlation was found between knowledge and clinical decision-making ability in pre-test(P=0.03)and in post-test(P<0.001)and a non-significant correlation was found between pre-test knowledge and self-efficacy score(P=0.52)among the experimental ***:Simulation-based learning regarding the management of post-COVID complications is effective among nursing *** labs should be established in health care settings where simulation training can be provided for updating the knowledge,clinical decision-making ability,and self-efficacy of nursing personnel during program installment and continuous nursing education.

关键词： Simulation Knowledge Clinical decision making ability Self-efficacy Post-COVID complications

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A novel sub 20 nm single gate tunnel field effect transistor with intrinsic channel for ultra low power applications

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Journal of Semiconductors 2016年第5期37卷 30-34页

作者： Pranav Kumar Asthana yogesh Goswami Bahniman Ghosh Department of Electrical Engineering Indian Institute of Technology Kanpur Microelectronics Research Center University of Texas at Austin

We propose a nanoscale single gate ultra thin body intrinsic channel tunnel field effect transistor using the charge plasma concept for ultra low power applications. The characteristics of TFETs （having low leakage） are improved by junctionless TFETs through blending advantages of Junctionless FETs （with high on current）. We further improved the characteristics, simultaneously simplifying the structure at a very low power rating using an InAs channel. We found that the proposed device structure has reduced short channel effects and parasitics and provides high speed operation even at a very low supply voltage with low leakage. Simulations resulted in Iovv of - 9 × 10-16A/um, IoN of ,-20uA/um, ION/IoFF of--2× 1010, threshold voltage of 0.057 V, subthreshold slope of 7 mV/dec and DIBL of 86 mV/V for PolyGate/HfO2/InAs TFET at a temperature of 300 K, gate length of 20 nm, oxide thickness of 2 nm, film thickness of 10 nm, low-k spacer thickness of 10 nm and VDD of 0.2 V.

关键词： band-to-band tunneling (BTBT) tunnel field effect transistor (TFET) junctionless tunnel field effecttransistor (JLTFET) ION/IOFF ratio low power

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Partial genomic organization of ribosomal protein S7 gene from malaria vector Anopheles stephensi

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Insect Science 2007年第2期14卷 101-106页

作者： RAJNIKANT DIXIT SARITA DIXIT UPAL ROY yogesh S.SHOUCHE SURENDRA GAKHAR Department of Biosciences Maharshi Dayanand University RohtakPune University Campus Pune India National Centre for Cell Science Pune University Campus Pune India

In this study, we describe the partial genomic organization of ribosomal protein S7 gene isolated from the mosquito Anopheles stephensi. Initially a 558 bp partial cDNA sequence was amplified as precursor mRNA sequence containing 223 bp long intron. 5＇ and 3＇ end sequences were recovered using end specific rapid amplification of cDNA ends （RACE） polymerase chain reaction. The full-length cDNA sequence was 914 nucleotide long with an open reading frame capable of encoding 192 amino acid long protein with calculated molecular mass of 22174 Da and a pI point of 9.94. Protein homology search revealed 〉75% identity to other insect＇s S7 ribosomal proteins. Analysis of sequence alignment revealed several highly conserved domains, one of which is related to nuclear localization signal （NLS） region of human rpS7. Interestingly, intron nucleotide sequence comparison with A. gambiae showed a lesser degree of conservation as compared to coding and untranslated regions. Like this, early studies on the genomic organization and cDNA/ Expressed sequence tag analysis （EST） could help in genome annotation ofA. stephensi, and would be likely to be sequenced in the future.

关键词： Anopheles malaria mosquito ribosomal protein vector

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Improved performance of naringenin herbosomes over naringenin in streptozotocin- induced diabetic rats: In vitro and in vivo evaluation

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Asian Pacific Journal of Tropical Biomedicine 2021年第9期11卷 385-393页

作者： Ruthvika Joshi Ankit P.Laddha yogesh A.Kulkarni Sarika Wairkar Shobhaben Pratapbhai Patel School of Pharmacy&Technology Management SVKM's NMIMSV.L.Mehta RoadVile Parle(W)Mumbai.Maharashtra-400056India

Objective:To prepare naringenin herbosome and evaluate its antidiabetic ***:Herbosomes were prepared by the solvent evaporation *** vitro parameters like particle size,polydispersity index,zeta potential,and entrapment efficiency were estimated and in vitro diffusion study was *** in vivo studies were also performed in streptozotocin-induced diabetic male Sprague Dawley rats to evaluate blood glucose,total cholesterol,triglyceride,blood urea nitrogen,total protein,albumin level,aspartate aminotransferase,and alanine aminotransferase ***:The optimized herbosome batch showed a particle size of 564.4 nm,a polydispersity index of 0.412,and zeta potential of−39.3 *** percentage entrapment of this formulation was 84.04%,with complete drug release within 8 *** of diabetic rats with naringenin herbosomes for 28 d significantly reduced the elevated level of plasma glucose as compared to plain *** biochemical parameters,the treatment showed a significant decrease in total cholesterol,triglyceride,and blood urea nitrogen;while elevated levels of aspartate aminotransferase and alanine aminotransferase were returned to *** naringenin and herbosome formulation at high dose increased the total protein whereas albumin level significantly increased in naringenin herbosomes at the highest dose but not in the pure naringenin treatment ***:Naringenin herbosomes could improve the metabolic profile of diabetic rats,indicating enhanced antidiabetic activity of herbosome formulation.

关键词： Naringenin Herbosomes Blood glucose level Biochemical parameters Antidiabetic activity

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Machine learning and evolutionary prediction of superhard BC-N compounds

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npj Computational Materials 2021年第1期7卷 1034-1041页

作者： Wei-Chih Chen Joanna N.Schmidt Da Yan yogesh K.Vohra Cheng-Chien Chen Department of Physics University of Alabama at BirminghamBirminghamALUSA Department of Computer Science University of Alabama at BirminghamBirminghamALUSA

We build random forests models to predict elastic properties and mechanical hardness of a compound,using only its chemical formula as *** model training uses over 10,000 target compounds and 60 features based on stoichiometric attributes,elemental properties,orbital occupations,and ionic bonding *** the models,we construct triangular graphs for B-C-N compounds to map out their bulk and shear moduli,as well as hardness *** graphs indicate that a 1:1 B-N ratio can lead to various superhard *** also validate the machine learning results by evolutionary structure prediction and density functional *** study shows that BC_(10)N,B_(4)C_(5)N_(3),and B_(2)C_(3)N exhibit dynamically stable phases with hardness values>40 GPa,which are superhard materials that potentially could be synthesized by low-temperature plasma methods.

关键词： prediction moduli occupation

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The incidence of sporadic viral hepatitis in North India:a preliminary study

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Hepatobiliary & Pancreatic Diseases International 2007年第6期6卷 596-599页

作者： Subrat Kumar Radha Kanta Ratho yogesh Kumar Chawla Anuradha Chakraborti Department of Virology Department of Hepatology Department of Experimental Medicine and Biotechnology

BACKGROUND: Viral hepatitis is one of the major causes of mortality and morbidity in developing countries. Hepatitis E virus (HEV) among the major etiological agents is responsible for both sporadic and epidemic outbreaks. The epidemic outbreak is water-borne whereas the sporadic outbreak is possibly through contact. Various diagnostic tools at times fail to pinpoint the cause of viral hepatitis. This study was carried out to evaluate the utility of ELISA and nRT-PCR (nested reverse transcriptase polymerase chain reaction) for the diagnosis of sporadic and acute viral hepatitis (AVH) caused by HEV in an endemic situation in North India. METHODS: Serum samples were collected from all the affected and suspected persons and subjected to serological detection of HAV IgM, HBsAg, HCV antibody and HEV IgM. The samples that were positive for HEV IgM were further processed for the detection of HEV RNA by nRT-PCR. RESULTS: A total of 843 samples were collected from 685 patients with AVH, 70 patients with fulminant hepatic failure (FHF), 53 patients with chronic liver disease (CLD), 11 patients with antituberculosis therapy (ATT)-induced jaundice, and 24 pregnant women. The percentage of positivity for anti-HEV IgM was 58.3% in the pregnant women, 41.4% in the paients with FHF, 38.6% in the patients with AVH, 9.4% in the patients with CLD and 18.2% in the patients with ATT induced jaundice. 9.4% of HBsAg carriers were positive for anti-HEV IgM. Males outnumbered females (62.8% vs. 37.1%). Furthermore, the rates of fulminant and acute outbreaks of hepatitis with HEV RNA positivity were 41.4% and 9.4%, respectively. CONCLUSION: Serological and molecular analysis should be combined for the diagnosis of viral infections, especially in endemic areas.

关键词： viral hepatitis fulminant liver failure pregnancy

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Ecological variables influencing the diversity and distribution of macrolichens colonizing Quercus leucotrichophora in Uttarakhand forest

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Journal of Mountain Science 2018年第2期15卷 307-318页

作者： Shashi UPADHYAY Arun K.JUGRAN yogesh JOSHI Renu SUYAL Ranbeer S.RAWAL Lichenology laboratory S.S.J.Campus Kumaun University Biodiversity Conservation & Management Ecosystem Services and Climate Change Group G.B.Pant National Institute of Himalayan Environment and Sustainable Development G.B.Pant National Institute of Himalayan Environment and Sustainable Development Garhwal Unit

Ecological variables play a significant role in determining the diversity and distribution of any living organism on earth. Lichens are not exceptional and are quite sensitive in comparison to other organisms; hence the present study focuses on the impact of ecological variables on the diversity and distribution of epiphytic macrolichens colonizing Quercus leucotrichophora across eight different sites(50 m × 50 m) in Thal Ke Dhar forest, Kumaun Himalaya, Uttarakhand, India. For sampling of macrolichens, 200 trees(25 trees from each site) of *** were selected from each site and five quadrats of 5 cm × 10 cm(1000 quadrats in totality) were drawn at the tree trunk. From all the sampled trees, a total of 54 species of epiphytic macrolichens belonging to 18 genera and five families were recorded. Various ecological variables, namely altitude, aspect, slope, diameter at breast height(DBH), and lopping percent(partial cutting of the twigs as disturbance), were also analyzed to investigate their influence on macrolichen species composition and distribution pattern in the study area. For the determination of relationships between these variables, statistical analysis, namely Pearson's Correlation Coefficient, Polynomial regression analysis and Principal Component Analysis(PCA)were performed. Out of all variables, lopping was significantly correlated to species richness of epiphytic macrolichens(0.712~*, p<0.05) and it was confirmed by Pearson's Correlation *** of having high anthropogenic pressure or impact through lopping, the maximum number of macrolichen species was recorded at elevation 2267 meter above sea level(m asl). The present study revealed that besides other ecological variables,lopping practices can act as a key parameter incontrolling the diversity and distribution not only of epiphytic macrolichens but also of other life forms such as bryophytes, pteridophytes, insects, birds *** can be either negatively or positively correla

关键词：分发模式殖民地生态森林附生植物关联系数统计分析主要部件

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All-optical active THz metasurfaces for ultrafast polarization switching and dynamic beam splitting

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Light(Science & Applications) 2018年第1期7卷 766-774页

作者： Longqing Cong yogesh Kumar Srivastava Huifang Zhang Xueqian Zhang Jiaguang Han Ranjan Singh Division of Physics and Applied Physics School of Physical and Mathematical SciencesNanyang Technological University21 Nanyang LinkSingapore 637371Singapore Centre for Disruptive Photonic Technologies The Photonics InstituteNanyang Technological University50 Nanyang AvenueSingapore 639798Singapore Center for Terahertz Waves and College of Precision Instrument and Optoelectronics Engineering Key Laboratory of Optoelectronic Information TechnologyMinistry of EducationTianjin University300072 TianjinPeople’s Republic of China

Miniaturized ultrafast switchable optical components with an extremely compact size and a high-speed response will be the core of next-generation all-optical devices instead of traditional integrated circuits,which are approaching the bottleneck of Moore’s *** have emerged as fascinating subwavelength flat optical components and devices for light focusing and holography ***,these devices exhibit a severe limitation due to their natural passive *** we introduce an active hybrid metasurface integrated with patterned semiconductor inclusions for all-optical active control of terahertz *** modulation of polarization states and the beam splitting ratio are experimentally demonstrated on a time scale of 667 *** scheme of hybrid metasurfaces could also be extended to the design of various free-space all-optical active devices,such as varifocal planar lenses,switchable vector beam generators,and components for holography in ultrafast imaging,display,and high-fidelity terahertz wireless communication systems.

关键词： polarization optical beam

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Structural,magnetic and dielectric properties of nano-crystalline Ni-doped BiFeO_(3) ceramics formulated by self-propagating high-temperature synthesis

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Journal of Advanced Ceramics 2013年第2期2卷 135-140页

作者： yogesh A.CHAUDHARI Chandrashekhar M.MAHAJAN Prashant P.JAGTAP Subhash T.BENDRE Department of Physics School of Physical SciencesNorth Maharashtra UniversityJalgaon 425001India Department of Engineering Sciences and Humanities(DESH) SRTTC-FOEKamshetPune 410405India Department of Engineering Sciences and Humanities(DESH) Vishwakarma Institute of Technology(VIT)Pune 411037India

Ni-doped BiFeO_(3) powders with the composition BiFe_(1-x)Ni_(x)O_(3)(x=0.05,0.1 and 0.15)were prepared by a self-propagating high-temperature synthesis(SHS),using metal nitrates as oxidizers and glycine as *** X-ray diffraction(XRD)patterns depict that Ni-doped BiFeO_(3) ceramics crystallize in a rhombhohedral *** scanning electron micrographs of Ni-doped BiFeO_(3) ceramics show a dense morphology with interconnected *** is found that,the room-temperature magnetization measurements in Ni-incorporated BiFeO_(3) ceramics give rise to nonzero *** magnetization of Ni-doped BiFeO_(3) ceramics is significantly enhanced when Ni doping concentration reaches to x=0.1 at 5 *** variations of dielectric constant with temperature in BiFe_(0.95)Ni_(0.05)O_(3),BiFe_(0.9)Ni_(0.1)O_(3) and BiFe_(0.85)Ni_(0.15)O_(3) samples exhibit clear dielectric anomalies approximately around 450℃,425℃and 410℃respectively,which correspond to antiferromagnetic to paramagnetic phase transition of the parent compound BiFeO_(3).

关键词： Ni-doped BiFeO_(3) self-propagating high-temperature synthesis(SHS) X-ray diffraction(XRD) magnetic properties dielectric properties

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The use of hydrogel-delivered extracellular vesicles in recovery of motor function in stroke:a testable experimental hypothesis for clinical translation including behavioral and neuroimaging assessment approaches

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Neural Regeneration Research 2021年第4期16卷 605-613页

作者： Magdalini Tsintou Kyriakos Dalamagkas Tara LMoore yogesh Rathi Marek Kubicki Douglas LRosene Nikos Makris Departments of Psychiatry and Neurology Services Center for Neural Systems InvestigationsCenter for Morphometric AnalysisAthinoula A.Martinos Center for Biomedical ImagingMassachusetts General HospitalHarvard Medical SchoolBostonMAUSA Department of Psychiatry Psychiatry Neuroimaging LaboratoryBrigham and Women’s HospitalHarvard Medical SchoolBostonMAUSA University College of London Division of Surgery&Interventional Science Center for Nanotechnology&Regenerative MedicineUniversity College LondonLondonUK Department of Physical Medicine and Rehabilitation The University of Texas Health Science Center at HoustonHoustonTXUSA The Institute for Rehabilitation and Research Memorial Hermann Research Center The Institute for Rehabilitation and Research Memorial Hermann HospitalHoustonTXUSA Department of Anatomy&Neurobiology Boston University School of MedicineBostonMAUSA

Neural tissue engineering,nanotechnology and neuroregeneration are diverse biomedical disciplines that have been working together in recent decades to solve the complex problems linked to central nervous system(CNS)*** is known that the CNS demonstrates a very limited regenerative capacity because of a microenvironment that impedes effective regenerative processes,making development of CNS therapeutics *** the high prevalence of CNS conditions such as stroke that damage the brain and place a severe burden on afflicted individuals and on society,it is of utmost significance to explore the optimum methodologies for finding treatments that could be applied to humans for restoration of function to pre-injury *** vesicles(EVs),also known as exosomes,when derived from mesenchymal stem cells,are one of the most promising approaches that have been attempted thus far,as EVs deliver factors that stimulate recovery by acting at the nanoscale level on intercellular communication while avoiding the risks linked to stem cell *** the same time,advances in tissue engineering and regenerative medicine have offered the potential of using hydrogels as bio-scaffolds in order to provide the stroma required for neural repair to occur,as well as the release of biomolecules facilitating or inducing the reparative *** review introduces a novel experimental hypothesis regarding the benefits that could be offered if EVs were to be combined with biocompatible injectable *** rationale behind this hypothesis is presented,analyzing how a hydrogel might prolong the retention of EVs and maximize the localized benefit to the *** sustained delivery of EVs would be coupled with essential guidance cues and structural support from the hydrogel until neural tissue remodeling and regeneration ***,the importance of including nonhuman primate models in the clinical translation pipeline,as well as the added benefit of m

关键词： cortical injury exosomes extracellular vesicles hydrogels neural tissue engineering neural tissue repair neuroregeneration non-human primates stroke

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