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A Critical Review on Traditional Herbal Drugs: An Emerging Alternative Drug for Diabetes

International Journal of Organic Chemistry 2013年第1期3卷 1-22页

作者： Krishna Bihari Pandeya Indra Prasad Tripathi Mahendra Kumar Mishra Neelesh Dwivedi yogesh Pardhi Arti Kamal Priyanka Gupta Nupa Dwivedi Chinmayi Mishra Faculty of Science & Environment Mahatma Gandhi Chitrakoot Gramoday Vishwavidyalaya Chitrakoot India Reseach Assistant Tropical Forest Research Institute (TFRI) Jabalpur India Research Scholar Mahatma Gandhi Chitrakoot Vishwavidyalaya Chitrakoot India Vice-Chancellor Mahatma Gandhi Chitrakoot Vishwavidyalaya Chitrakoot India

Diabetes is a chronic metabolic disease reaching an epidemic proportion in many parts of the world. By the year 2025 it is expected that 333 million people of the world will have diabetes as their main ailment. As today, India assumes the position of the diabetic capital of the world with the highest percentage of its population suffering from diabetes. It is pathetic to mention that in proportion to its people suffering from diabetes, this country has very weak spending power for treatment because of wide spread poverty. Therefore, this review is aimed at opening up new vistas in realizing the therapeutic potential of Ayurveda in treatment of diabetes and other chronic diseases. All drugs which we have discussed in this review have a significant role in therapy of diabetes mellitus.

关键词： Diabetes Mellitus Metabolic Disease Ayurveda Hyperglycemia Synthetic Drugs Herbal Drugs Metallo Therapy Oral Hypoglycemic Drugs

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Removal of Malathion from Aqueous Solutions and Waste Water Using Fly Ash

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Journal of Water Resource and Protection 2010年第4期2卷 322-330页

作者： Vinay K. Singh Ravi S. Singh Prem N. Tiwari Jai K. Singh Fethiye Gode yogesh C. Sharma 不详

Fly ash, obtained from a thermal power plant, Anpara, Sonebhadra, India has been used as an effective ad-sorbent for the removal of malathion from aqueous solutions. The time required to attain equilibrium was found to increase from 40 to 60 minutes as the initial malathion concentration increases from 1 to 10 mg/L. The optimum pH value for adsorption was 4.50. The removal of malathion increased by increasing the tem-perature indicating endothermic nature of removal process. The fly ash exhibited first order rate kinetics and followed both Langmuir and Freundlich isotherm models. Endothermic nature of adsorption process was further supported from increasing values of Langmuir and Freundlich constants with increase in temperature. The adsorbent can be used as an economical product for the removal of malathion from wastewater also. A comparison of the adsorption capacity of fly ash with other adsorbents shows that fly ash can be used for the removal of malathion from aqueous solutions.

关键词： Adsorption Wastewater Removal Fly Ash Malathion

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打造未来的供应链

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石油石化物资采购 2012年第2期 76-77页

作者：樊晓武 yogesh Malik Alex Niemeyer Brian Ruwadi 不详麦肯锡克利夫兰分公司迈阿密分公司

实现这一目标就意味着，摒弃现今整体供应链的模式而支持分裂的供应链，消解复杂性，并利用制造的网络化防备不确定性。

关键词：供应链不确定性复杂性

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打造未来的供应链(二)

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石油石化物资采购 2012年第3期 80-81页

作者：樊晓武(译) yogesh Malik Alex Niemeyer Brian Ruwadi 不详麦肯锡克利夫兰分公司迈阿密分公司

把一个供应链分解成若干子供应链，这种做法使得公司减少了复杂性，优化了管理，因为经营资产可以被集中到企业最有能力处理的任务上。

关键词：供应链复杂性企业资产

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用于集成电路仿真和设计的FinFET建模

用于集成电路仿真和设计的FinFET建模

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作者： (印)尤盖希·辛格·楚罕(yogesh Singh Chauhan)[等]

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中国西南部Pilophorus属(石蕊科)的分类学研究(英文)

中国西南部Pilophorus属(石蕊科)的分类学研究(英文)

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2010全国地衣与苔藓系统学研讨会

作者：王新宇 yogesh Joshi Soon-Ok Oh Jae Seoun Hur 王立松 Korean Lichen Research Institute Sunchon National UniversitySunchon 540-742Korea Key Laboratory of Biodiversity and Biogeography Kunming Institute of BotanyChinese Academy of SciencesHeilongtanKunming

A comprehensive analysis of the genus Pilophorus from China was performed in this *** species of Pilophorus were recognized from *** them,*** and P. fruticusus are described as two new *** is characterized by the extremely short podetia(<1mm) and scattered primary thallus,*** is characterized by the umbellately branched podetia and globose *** rest four species include all the species reported in China *** result suggests that several characters are important in the taxonomy of this genus:sorediate or not,podetia branched or not,shape of the apothecia and the primary thallus. Description of each species was presented with morphological and chemical characters.A key to the genus was also presented.

关键词： Pilophorus Lichenized ascomycetes Southwestern China New species

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打造未来的供应链(三)

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石油石化物资采购 2012年第4期 87-87页

作者： yogesh Malik Alex Niemeyer Brian Ruwadi 樊晓武（译）麦肯锡克利夫兰分公司迈阿密分公司《石油石化物资采购》编辑部

如果公司对多供应链进行动态的考察,着眼于整个供应链在各种情况下的弹性能力,就会发现多供应链的优势极具价值。

关键词：供应链企业供销管理成本结构

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Efficacy and Safety of Tinefcon^® Tablets in Subjects with Plaque Psoriasis: An Open Label, Non-Comparative, Multicenter, Phase IV Trial

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Journal of Cosmetics, Dermatological Sciences and Applications 2016年第2期6卷 55-66页

作者： Somesh Sharma Kailash Bhatia Meetesh Agarwal Sandesh Gupta Leelavathi Budamakuntla Sudhakar Grandhi Vinod Titarmare Sushil Pande Ranjan Rawal Aruna Samarth Rizwan Haq Vikrant Saoji D. V. S. Pratap L. M. Kansal D. G. Saple Shatrughan Sahay Parag Kalyani Puneet Goyal Sharmila Patil A. J. Kanwar Bhavesh Swarnakar Sujay Kulkarni Abhijeet Morde Hitesh Khandagale yogesh Dound Nitin Jadhav Sanjeev Hegde Murlidhara Padigaru Ashish C. Suthar Piramal Enterprises Limited Mumbai India Bhatia Skin Center Bima Nagar Indore India Agrawal Path LAB Vijaynagar Indore India Skin & Laser Center Krishna Nagar New Delhi India Diabetes and Shirdi Skin Care Centre Karnataka India Medipoint Hospitals Pvt. Ltd. Pentagon Research Pvt. Ltd. Pune India Skin Care Clinic Nagpur India NKP Salve Institute and Lata Mangeshkar Hospital Nagpur India Department of Dermatology Sheth VS General Hospital Ahmedabad India Sai Skin Care Clinic Hyderabad India Radiance Skin Care Clinic Nagpur India Dr. Vikrant Saoji’s Clinic Ramdaspeth Nagpur India Durgabai Deshmukh Hospital & Research Center Hyderabad India Kansal Cosmetic & Skin Care Clinic Jaipur India Dr. Saple’s Clinic Dadar (East) Mumbai India Sri Skin Care & Laser Clinic Lucknow UP India Ruby Hall Clinic Pune India Renova Skin & Laser Clinic Sector-9 Mansarovar Jaipur India Dr. D. Y. Patil Medical College and Hospital Nerul Navi Mumbai India Department of Dermatology Venerology & Leprology Postgraduate Institute of Medical Education and Research Chandigarh India Swarnakar Superspeciality Centre Indore India Clinical Research and Development Piramal Enterprises Limited Mumbai India

Importance: This post-marketing surveillance study was conducted to evaluate real-world information about the efficacy and safety of oral Tinefcon? tablets (Sphaeranthus indicus based) in plaque psoriasis patients. Materials and Methods: Patients aged at least 18 years and older with clinical diagnosis of plaque psoriasis, were enrolled in this open label, non-comparative, multicenter trial. All eligible subjects received four 700 mg Tinefcon? tablets/day for 12 weeks. The primary outcome measure was percent change in Psoriasis Area Severity Index (PASI) score from baseline to week 12. The secondary outcome measures were Physician Global Assessment (PGA), Nail Psoriasis Severity Index (NAPSI), Psoriatic Arthritis Evaluation and Gene Expression Profiling and Immunohistochemistry. Results: After completion of Tinefcon? treatment at 12 weeks, more than half of subjects (52%) achieved PASI 50 response;PASI 75 response was attained in 68 (23%) subjects and PASI 90 response in 22 (7%) subjects. Five subjects with severe psoriasis achieved PASI 90 without receiving any concomitant medication. Reduction in severity as assessed by PGA was observed in more than half of patients with moderate disease. Histopathological evaluation revealed that epidermal thickness was considerably reduced in 66% of subjects. The expression of inflammatory marker S100A9 protein was(meaningfully reduced in 60% patients with non-significant reduction of Keratin 10 protein expression. Gene expression analysis showed increase down regulation of SERPINB4;PI3 and KRT16 genes after a 12-week treatment period in subjects with higher PASI scores. Conclusion: Oral Tinefcon? tablets showed good efficacy and had a favorable safety profile in plaque psoriasis patients.

关键词： Psoriasis Tinefcon® Tablet Sphaeranthus indicus

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