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A comparative study of the anti-fatigue activity of extracts from different parts of Cistanche tubulosa(Schenk)Wight Author links open overlay panel

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Journal of Traditional Chinese Medical Sciences 2024年第2期11卷 222-231页

作者： Jianteng Dong Junjun Li yizhou liu Lingwen Cui Xiangning liu Gang Wang Qixin Wang David N.Criddle Pengfei Tu Chun Li School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing102488China Modern Research Center for Traditional Chinese Medicine School of Chinese Materia MedicaBeijing University of Chinese MedicineBeijing102488China Institute of Chinese Materia Medica China Academy of Chinese Medical SciencesBeijing100700China Department of Molecular&Clinical Cancer Medicine Institute of SystemsMolecular&Integrative BiologyUniversity of LiverpoolLiverpoolL693BXUK Peking University School of Pharmaceutical Sciences Beijing100191China

Objective To evaluate the anti-fatigue effects of different extracts from Cistanche tubulosa(Schenk)Wight(***,Rou Cong Rong),focusing on central and exercise-induced fatigue in *** study investigated the pharmacological effects of the total oligosaccharides,polysaccharides,and phenylethanoid glycosides(CPhGs)extracted from *** Models of sleep deprivation and forced swimming fatigue were established to simulate central and exercise-induced *** mice were treated with different extracts of ***,and their effects were assessed using behavioral tests to measure exercise capacity,learning,and memory *** analyses were performed to evaluate the changes in serum and brain neurotransmitter levels,liver and muscle glycogen storage,and various fatigue-related *** This study found that treatment with *** extract improved exercise capacity,learning,and memory in *** oligosaccharides from *** enhanced adrenocorticotropic hormone,cholinesterase,and thyroid-stimulating hormone levels,reduced cortisol levels in central fatigue models,and ameliorated biochemical markers of exercise-induced fatigue,including lowering lactic acid,blood urea nitrogen,and malondialdehyde *** the tested extracts,the total oligosaccharides showed the most comprehensive anti-fatigue *** The anti-fatigue effects of ***,particularly those of its total oligosaccharides,are pronounced in both central and exercise-induced *** effects are mediated by the regulation of neurotransmitter levels,enhancement of glycogen storage,and improvement of antioxidant enzyme activity,suggesting potential therapeutic benefits in fatigue-related conditions.

关键词： Cistanche tubulosa Anti-fatigue Central fatigue Exercise fatigue Oligosaccharides

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社会信息加工视角下网络舆情群体智慧涌现机理

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情报杂志 2024年第10期43卷 116-126页

作者：刘毅洲黄微吉林大学商学与管理学院长春130022

[研究目的]厘清网络舆情群体智慧涌现机理可洞察复杂舆情场内的信息价值,为网络舆情的知识管理提供理论依据。[研究方法]在群体智慧涌现的性态刻画基础上,基于社会信息加工理论构建机理集成模型,包括认知触发机理、协同标注机理、观点... 详细信息

[研究目的]厘清网络舆情群体智慧涌现机理可洞察复杂舆情场内的信息价值,为网络舆情的知识管理提供理论依据。[研究方法]在群体智慧涌现的性态刻画基础上,基于社会信息加工理论构建机理集成模型,包括认知触发机理、协同标注机理、观点交互对抗机理、时效控制机理、平台响应机理,并讨论子机理间的作用关系,通过实证分析证明机理研究的合理性。[研究结论]网络舆情群体智慧涌现具有复杂非线性系统特征,知识实体符合幂律分布规律。网络群体在舆情观点发散阶段的知识密度较高,在舆情观点聚合阶段群体智慧涌现并不明显,观点分散造成的信息异质环境并不是激发群体智慧的充要条件。

关键词：网络舆情群体智慧涌现机理性态刻画知识实体非线性涌现社会信息加工理论

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Triplex-structure based DNA circuits with ultra-low leakage and high signal-to-noise ratio

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Chinese Chemical Letters 2024年第1期35卷 465-470页

作者： Huan liu Zhihao Ming Yuanpeng Zhang Qidong Xia Hao Hu Ruijie liu Yuheng Liao yizhou liu Xiao liu Xiaoping Zhang Longjie Li Shaogang Wang Xianjin Xiao Institute of Reproductive Health Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department and Institute of Urology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department and Institute of Urology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China School of Life Science and Technology Wuhan Polytechnic UniversityWuhan 430030China Department of Laboratory Medicine Tongji hospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

DNA circuits are powerful tools in various applications such as logical computation,molecular diagnosis and synthetic *** is a major problem in constructing complex DNA *** directly affects the output signal and harms the circuit’s performance *** the traditional DNA circuits,the gate complex is a duplex *** are insufficient energy barriers to prevent spontaneous detachment of strands,resulting in a leak ***,we have developed triplex-structure based DNA circuit with ultra-low leakage and high signal-to-noise ratio(SNR).The triplex structure improves the stability in the absence of *** the same time,the driving force of the strand displacement cascades reduces the influence of the triplex structure on the desired *** SNR of the DNA circuit was increased to 695,while the desired reaction rate remained 90%of the conventional translator *** triplex-structure mediated leakage prevention strategy was further tested at different temperatures and in DNA translator and seesaw *** also constructed modular basic logic gates with a high efficiency and low *** this basis,we further constructed triplex-structure based tertiary DNA logic circuits,and the SNR reached 295,which,to the best of our knowledge,was among the highest of the *** believe that our scheme provides a novel,valid,and general tool for reducing leakages,and we anticipate that it will be widely adopted in DNA nanotechnology.

关键词： Leakage DNA strand displacement cascades Triplex DNA circuits Molecular programming

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An Automated,Highly Selective Reaction Monitoring Instrument Using Molecular Rotational Resonance Spectroscopy

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Precision Chemistry 2024年第2期2卷 57-62页

作者： Ann Adele Byars Khushi R.Kompally Emily Mechnick Reilly E.Sonstrom Alexander Mikhonin Justin L.Neill Ruth Boetzel James MacGregor Courtney Talicska Jian Li yizhou liu BrightSpec Inc.CharlottesvilleVirginia 22903United States Pfizer R&D UK Limited Sandwich CT139NJUnited Kingdom Analytical Research and Development Pfizer Research and DevelopmentGrotonConnecticut 06340United States

Online monitoring of chemical reactions by using analytical chemistry tools is a powerful way to maximize control over these *** this paper,we demonstrate the use of molecular rotational resonance,an emerging and extraordinarily selective spectroscopic technique,to perform automated reaction monitoring *** interface using a six-port valve with a calibrated sample loop,coupled to a temperature controlled inlet for analyte volatilization,was developed and *** reactions were chosen for initial characterization:an amine-aldehyde condensation reaction to form an imine product and an isotopic exchange reaction of aβ-ketoester with keto-enol *** spectrometer was able to provide kinetic information about the reaction and determine reaction *** the future,this system can be extended to detect and quantify impurities and characterize reaction selectivity,in addition to the reaction progress.

关键词： molecular rotational resonance spectroscopy reaction monitoring reaction kinetics isotopes process analytical technology

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早期腔隙性脑梗死CT和MRI检查的诊断效能分析

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世界复合医学 2024年第5期10卷 149-152页

作者：刘沂洲临沂老年医院有限公司影像科山东临沂276000

目的探讨CT检查和磁共振成像(magnetic resonance imaging,MRI)检查对早期腔隙性脑梗死的诊断效能。方法选取2020年2月—2023年2月临沂老年医院有限公司收治的40例疑似早期腔隙性脑梗死患者为研究对象。所有研究对象均接受CT和MRI检... 详细信息

目的探讨CT检查和磁共振成像(magnetic resonance imaging,MRI)检查对早期腔隙性脑梗死的诊断效能。方法选取2020年2月—2023年2月临沂老年医院有限公司收治的40例疑似早期腔隙性脑梗死患者为研究对象。所有研究对象均接受CT和MRI检查。以病理诊断为金标准,对CT及MRI的诊断效能、病灶大小检出情况、病灶位置检查情况进行统计分析,并计算诊断符合率。结果病理诊断确诊阳性患者25例,阴性患者15例。MRI各诊断效能值均高于CT,差异有统计学意义(P均5 mm的诊断符合率为98.67%(74/75)高于CT的17.86%(5/28)、33.33%(25/75),差异有统计学意义(χ^(2)=31.865、71.331,P均<0.05)。CT诊断顶叶、额叶、脑干以及基底节病灶的符合率低于MRI,差异有统计学意义(P均<0.05)。结论对早期腔隙性脑梗死,相比CT,MRI能够更清晰显示病灶信息,提高病灶检出率,避免微小病灶遗漏。

关键词：早期腔隙性脑梗死 CT MRI 临床影像学表现

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二维范德华磁体的拓扑自旋结构的研究进展

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Science Bulletin 2024年第11期69卷 1612-1616页

作者：许洪军刘艺舟 Giovanni Finocchio Kang LWang 于国强 Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsUniversity of Chinese Academy of SciencesChinese Academy of SciencesBeijing 100190China RIKEN Center for Emergent Matter Science(CEMS) Wako 351-0198Japan Department of Mathematical and Computer Sciences Physical Sciences and Earth SciencesUniversity of MessinaMessina 98166Italy Department of Electrical Engineering University of CaliforniaLos Angeles CA 90095USA

The importance of topological spin textures(TSTs), such as skyrmions, merons, hopfions, etc., is due to their static and dynamic properties [1]. They carry a topological number that characterizes the homotopy group Π_(n)(S^(2))(n ∈ Z) and classifies maps from S^(n) to S^(2)(e.g., the skyrmion winding number corresponds to Π_(2)(S^(2))).

关键词：自旋结构 topological homotopy

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考虑碳排放配额和碳交易的新能源电力系统日前优化调度

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电网与清洁能源 2024年第1期40卷 130-136页

作者：魏伟叶利方毅汪应春刘奕舟国网湖北省电力有限公司营销服务中心(计量中心) 湖北武汉443080 三峡大学电气与新能源学院湖北宜昌443002

在电力系统碳交易市场化的背景下,研究一种科学、有效的碳排放额度分配策略,具有重要的理论和实际意义。该文在新能源大规模接入的现状下,考虑限制排放主体的碳排放量,并在排放主体间建立碳交易模型,提出一种考虑碳排放配额和碳交易的... 详细信息

在电力系统碳交易市场化的背景下,研究一种科学、有效的碳排放额度分配策略,具有重要的理论和实际意义。该文在新能源大规模接入的现状下,考虑限制排放主体的碳排放量,并在排放主体间建立碳交易模型,提出一种考虑碳排放配额和碳交易的日前优化调度方法。分别构建火电和风电碳交易费用的模型,提出一种基于熵值法的碳排放额度分配策略,对区域电网基准线排放因子的权重进行重新分配;考虑到因风电接入而造成常规火电机组产生的额外碳排放量,在碳交易价格预测的基础上,计算不同类型机组的碳交易费用;以调度时段内系统总费用最小为优化目标,构建考虑碳排放交易的日前优化调度模型,并求解该模型。仿真结果验证了所提方法的正确性和有效性。

关键词：碳交易日前优化调度碳排放配额分配熵值法

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Berry phase and topological effects of phonons

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National Science Review 2018年第3期5卷 314-316页

作者： yizhou liu Yong Xu Wenhui Duan State Key Laboratory of Low Dimensional Quantum Physics Department of Physics Tsinghua University Collaborative Innovation Center of Quantum Matter RIKEN Center for Emergent Matter Science (CEMS) Institute for Advanced Study Tsinghua University

Phonons as collective excitations of lattice vibrations are the main heat carriers in *** effort has been devoted to the investigation of phonons and related properties,giving rise to an intriguing field of phononics,which is of great importance to many practical applications,including heat dissipation,thermal barrier coating,thermoelectrics and thermal control devices[1].Meanwhile,research into topology-related physics,awarded the 2016 Nobel Prize in Physics,has led to discoveries of various exotic quantum states of matter,including the quantum(anomalous/spin)Hall

关键词： Berry phase and topological effects of phonons TRS

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Three-Dimensional Topological States of Phonons with Tunable Pseudospin Physics

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Research 2019年第1期2019卷 753-760页

作者： yizhou liu Yong Xu Wenhui Duan State Key Laboratory of Low Dimensional Quantum Physics Department of PhysicsTsinghua UniversityBeijing 100084China Collaborative Innovation Center of Quantum Matter Beijing 100084China RIKEN Center for Emergent Matter Science(CEMS) WakoSaitama 351-0198Japan Institute for Advanced Study Tsinghua UniversityBeijing 100084China

Efcient control of phonons is crucial to energy-information technology,but limited by the lacking of tunable degrees of freedom like charge or *** we suggest to utilize crystalline symmetry-protected pseudospins as new quantum degrees of freedom to manipulate ***,we reveal a duality between phonon pseudospins and electron spins by presenting Kramerslike degeneracy and pseudospin counterparts of spin-orbit coupling,which lays the foundation for“pseudospin phononics”.Furthermore,we report two types of three-dimensional phononic topological insulators,which give topologically protected,gapless surface states with linear and quadratic band degeneracies,*** topological surface states display unconventional phonon transport behaviors attributed to the unique pseudospin-momentum locking,which are useful for phononic circuits,transistors,antennas,*** emerging pseudospin physics ofers new opportunities to develop future phononics.

关键词： topological protected phonon

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数字化转型背景下企业绿色创新绩效组态分析--基于TOE框架的fsQCA研究

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物流科技 2024年第2期47卷 1-6页

作者：刘一舟陈立梅南京邮电大学江苏南京210003

绿色创新作为企业高质量发展的关键选择,在不同的数字化转型模式下呈现出不同的绿色创新绩效。文章以中国A股医药制造企业为研究对象,基于TOE框架选取技术、组织和环境三个维度以及6个具有代表性的前因条件,采用模糊集定性比较分析方法... 详细信息

绿色创新作为企业高质量发展的关键选择,在不同的数字化转型模式下呈现出不同的绿色创新绩效。文章以中国A股医药制造企业为研究对象,基于TOE框架选取技术、组织和环境三个维度以及6个具有代表性的前因条件,采用模糊集定性比较分析方法,从组态视角探讨了不同数字化转型条件下企业获得高绿色创新绩效的条件组合。研究发现,高绿色创新绩效可归纳为雄狮型(数字技术应用驱动型)和群狼型(数字转型战略-数字合作环境共同驱动型)两种模式;数字技术应用与数字技术人才两个条件变量之间存在替代效应。企业应充分认识到不同条件组态的殊途同归效应,主动适应所在地的数字环境条件,注重数字组织与数字环境的适配,从而有效开展绿色创新活动。

关键词：医药制造企业高绿色创新绩效 TOE框架模糊集定性比较分析方法

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