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A Smart Wearable Ring Device for Sensing Hand Tremor of Parkinson’s Patients

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Computer Modeling in Engineering & Sciences 2021年第3期126卷 1217-1238页

作者： Haixia Yang yixian shen Wei Zhuang Chunming Gao Dong Dai Weigong Zhang School of Instrument Science and Engineering Southeast UniversityNanjing210096China School of Computer and Software Nanjing University of Information Science and TechnologyNanjing210044China School of Engineering and Technology University of WashingtonTacoma98402USA School of Cyber Science and Engineering Southeast UniversityNanjing210096China

Parkinson’s disease(PD)is a very common neurodegenerative disease that occurs mostly in the *** are many main clinical manifestations of PD,such as tremor,bradykinesia,muscle rigidity,*** on the current research on PD,the accurate and convenient detection of early symptoms is the key to detect *** the development of microelectronic and sensor technology,it is much easier to measure the barely noticeable tremor in just one hand for the early detection of Parkinson’s *** this paper,we present a smart wearable device for detecting hand tremor,in which MPU6050(MIDI Processing Unit)consisting of a 3-axis gyroscope and a 3-axis accelerometer is used to collect acceleration and angular velocity of *** analyzing the time of specific finger movements,we successfully recognized the tremor signals with high ***,with Bluetooth 4.0(Bluetooth Low Energy,BLE)and networking terminal ability,tremor data can be transferred to a monitoring device in real time with extremely lowenergy *** experimental results have shown that the proposed device(smart ring)is convenient for long-term tremor detection which is vital for early detection and treatment for Parkinson’s disease.

关键词： Parkinson’s disease tremor detection IMU sensor MPU6050 BLE

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网站制度对消费者信任影响的实证研究

管理学报 2012年第5期9卷 715-722页

作者：赵学锋陈传红申义贤华中科技大学管理学院河南省电力公司信阳供电公司

在制度信任相关研究的基础上,为了探究网站制度如何影响消费者对电子商务网站和卖家的信任,构建了一个以网站制度为控制手段促进消费者信任的研究模型,并提出了相关假设。通过问卷调查收集数据并进行了数据分析,研究结果表明,反馈机制... 详细信息

在制度信任相关研究的基础上,为了探究网站制度如何影响消费者对电子商务网站和卖家的信任,构建了一个以网站制度为控制手段促进消费者信任的研究模型,并提出了相关假设。通过问卷调查收集数据并进行了数据分析,研究结果表明,反馈机制、交易安全、服务承诺显著影响网站信任,在线服务对网站信任影响不显著;同时网站制度通过网站信任对卖家信任产生间接影响;网站信任直接影响卖家的信任,网站信任和卖家信任都对购买意愿有正向影响。

关键词：制度信任网站信任卖家信任网站制度

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适于物流配送车辆导航路径规划的路网阻抗确定方法研究

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交通科技 2008年第1期18卷 94-97页

作者：温惠英沈毅贤华南理工大学交通学院广州510640

路径规划是物流配送车辆导航系统的核心功能之一。路网阻抗是路径规划的基础。由于物流配送涉及多方面利益,因此确定路网阻抗需综合考虑各种道路与非道路的影响因素。文中就各影响因素的特点对其进行量化和量纲一的量化处理,利用层次分... 详细信息

路径规划是物流配送车辆导航系统的核心功能之一。路网阻抗是路径规划的基础。由于物流配送涉及多方面利益,因此确定路网阻抗需综合考虑各种道路与非道路的影响因素。文中就各影响因素的特点对其进行量化和量纲一的量化处理,利用层次分析法计算各影响因素组合权重,得出路网阻抗,为物流配送导航路径规划提供依据。

关键词：物流配送车辆导航路网阻抗层次分析法

单相变压器参数测定中试验表计不同接入方式的影响

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河南科技学院学报（自然科学版） 2013年第5期41卷 48-52页

作者：申一先方赞峰北京交通大学电气工程学院北京100044

根据单相变压器空载试验、短路试验与试验表计的特点,从理论上分析了电压表、电流表和功率表的相对位置对试验结果的影响,并依据分析结果设计3种不同接法的试验电路,然后利用简化的电路模型推导出3种不同试验电路所测试验数据的准确性,... 详细信息

根据单相变压器空载试验、短路试验与试验表计的特点,从理论上分析了电压表、电流表和功率表的相对位置对试验结果的影响,并依据分析结果设计3种不同接法的试验电路,然后利用简化的电路模型推导出3种不同试验电路所测试验数据的准确性,最后通过试验数据的验证,得出单相变压器空载试验和短路试验表计的正确接法.

关键词：单相变压器参数测定接入方式空载试验短路试验

基于Granger模型的交通投资建设与经济发展的关系研究

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武汉理工大学学报（交通科学与工程版） 2009年第4期33卷 699-702页

作者：张志峰温惠英沈毅贤广东省公路工程质量监测站广州510500 华南理工大学土木与交通学院广州510640

交通基础设施建设是交通运输发展的重要支撑和保障.要正确制定交通基础设施建设的投资策略,必须明确交通基础设施建设与经济发展的关系,但目前两者的关系仍缺乏确切论证.在统计分析的基础上,通过采用Granger因果关系检验模型,检验了我... 详细信息

交通基础设施建设是交通运输发展的重要支撑和保障.要正确制定交通基础设施建设的投资策略,必须明确交通基础设施建设与经济发展的关系,但目前两者的关系仍缺乏确切论证.在统计分析的基础上,通过采用Granger因果关系检验模型,检验了我国的五种运输方式的交通基础设施建设和经济发展之间的因果关系,得到各交通运输方式的基础设施建设对经济发展的影响程度.

关键词： Granger因果关系模型交通投资交通设施建设经济发展协整关系检验

Traditional Chinese Medicine syndrome analysis on oxaliplatin-induced peripheral neuropathy and clinical efficacy of Bushen Yiqi formula(补肾益气方):a prospective randomized controlled study

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Journal of Traditional Chinese Medicine 2023年第6期43卷 1234-1242页

作者： PAN Longci QI Chunhui shen Xubo HUANG yixian YANG Xinrong SUN Xianjun Department of Tradition Chinese Medicine Qingpu Branch of Zhongshan HospitalFudan UniversityShanghai 201700China Department of Oncology Shanghai Qingpu District Hospital of Traditional Chinese Medicine(the Clinical Base of The Institutes of Integrative MedicineFudan University)Shanghai 201799China Department of Oncology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China Department of Integrative Medicine Huashan HospitalFudan UniversityShanghai 200040China

OBJECTIVES:To analyze the distribution characteristics of Traditional Chinese Medicine(TCM)syndromes in patients with oxaliplatin-induced peripheral neuropathy(OIPN)and observe the clinical efficacy of Bushen Yiqi formula(补肾益气方,BSYQF)in treating patients with ***:A total of 89 patients with OIPN were enrolled in this *** TCM syndrome characteristics were investigated by frequency analysis methodology after collecting and analyzing the TCM syndrome elements of the patients with the OIPN TCM syndrome element ***,62 cases of cold-dampness obstruction syndrome and kidney-Qi deficiency and cold syndrome were selected and randomly divided into the control group(n=31)and the treatment group(n=31).The patients in the treatment group were treated with modified BSYQF,while those in the control group were treated with mecobalamin tablets for 3 *** Levi sensory neurotoxicity score and the neuro-electrophysiological changes were observed before and after the treatment in both ***:The distribution of TCM syndrome types in 89 patients with OIPN were in order of kidney-Qi deficiency and cold syndrome(44 cases),cold-dampness obstruction syndrome(18 cases),Yin deficiency of liver and kidney syndrome(11 cases),blood stasis obstruction syndrome(7 cases),and dampness-heat obstruction syndrome(5 cases).Improvement in Levi sensory neurotoxicity score:After 3-week treatment,the total effective rate in the treatment group was higher than that in the control group(P<0.05).The subgroup analysis showed that the total effective rate in the treatment group of patients with kidney-Qi deficiency and cold syndrome was higher than that in the control group before and after treatment(P<0.05).Improvement in nerve conduction velocity:The sensory nerve conduction velocity of bilateral ulnar nerves improved in the control group after treatment compared with that before treatment(P<0.05).The sensory and motor nerve conduction velocities of the bilateral ulnar and

关键词： oxaliplatin peripheral nervous system diseases syndrome and complex nerve conduction velocity Bushen Yiqi formula

Biochar-Induced Priming Effects in Young and Old Poplar Plantation Soils

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Phyton-International Journal of Experimental Botany 2020年第1期89卷 13-26页

作者： Weiwei Lu Yirui Zhang yixian Yao Yuying Wu Han Y.H.Chen Hailin Zhang Jia Yu Caiqin shen Qi Liu Honghua Ruan College of Biology and the Environment Co-Innovation Center for Sustainable Forestry in Southern ChinaNanjing Forestry UniversityNanjing210037China Faculty of Natural Resources Management Lakehead UniversityThunder BayONP7B 5E1Canada Department of Plant and Soil Sciences Oklahoma State UniversityStillwaterOK74078USA Advanced Analysis and Testing Center Nanjing Forestry UniversityNanjing210037China State Owned Forest Farm of Dongtai Dongtai224200China College of Forestry Nanjing Forestry UniversityNanjing210037China

The priming effect(PE)induced by biochar provides a basis for evaluating its carbon(C)sequestration potential in soils.A 60 days’laboratory incubation was conducted,which involved the amendment of biochar(1%of soil mass)produced from rice straw at 300℃(B300)and 500℃(B500)to young(Y)and old(O)poplar plantation soils,with the aim of studying the responses of biochar-induced PEs to poplar plantation *** incubation included six treatments:Y+CK(control),Y+B300,Y+B500,O+CK,O+B300,and O+*** dioxide(CO_(2))emissions were significantly increased(p<0.05)in the B300 amended soils,while it was decreased in the B500 amended soils compared to the *** primed CO_(2) emissions were 2.35 times higher in the Y+B300 than the O+B300 treatments,which was measured to be 18.6 and 5.56 mg C·kg^(-1) with relative PEs of 12.4%and 3.35%,***,there was little difference between the primed CO_(2) emissions in Y+B500 and O+B500 treatments,which were measured to be-24.9 and-29.6 mg·C·kg^(-1) with relative PEs of-16.6%and-17.8%,*** organic carbon(DOC)was significantly lower in the young poplar plantation soil than that in the old poplar plantation soil regardless of biochar amendment throughout the incubation,indicating greater C-limit of soil microorganisms in the young poplar plantation *** ^(13)C isotope tracing,neither B300 nor B500 decreased native soil-derived DOC,which indicated that the negative B500-induced PEs were not due to a reduction in the availability of native soil-derived *** conclusion,the response of biochar-induced PEs to poplar plantation age depends on biochar types while soil available C indirectly affects biochar-induced *** studies should focus on how the interactive effects between soil C availability and microbial community impacts biochar-induced PEs.

关键词： Biochar dissolved organic carbon pyrolysis temperature poplar plantation age priming effect

Atherosclerosis-related biomarker PABPC1 predicts pan-cancer events

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Stroke & Vascular Neurology 2024年第2期9卷 108-125,I0001-I0005页

作者： Miao Lin Liubing Hu Si shen Jiyue Liu Yanyan Liu yixian Xu Honglin Chen Kazuo Sugimoto Jianshuang Li Ikuo Kamitsukasa Takaki Hiwasa Hao Wang Anding Xu Stroke Center The First Affiliated HospitalJinan UniversityGuangzhouChina Department of Anesthesiology The First Affiliated HospitalJinan UniversityGuangzhouChina The Biomedical Translational Research Institute Faculty of Medical ScienceJinan UniversityGuangzhouChina Department of Radiology Medical Imaging CenterThe First Affiliated HospitalJinan UniversityGuangzhouChina Department of Biochemistry and Genetics Graduate School of MedicineChiba UniversityChibaJapan Department of Neurology Dongzhimen HospitalBeijing University of Chinese MedicineBeijingChina Department of Neurology Chiba Rosai HospitalChibaJapan Department of Neurology Chibaken Saiseikai Narashino HospitalChibaJapan Department of Neurological Surgery Graduate School of MedicineChiba UniversityChibaJapan

Background Atherosclerosis(AS)and tumours are the leading causes of death worldwide and share common risk factors,detection methods and molecular ***,searching for serum markers shared by AS and tumours is beneficial to the early diagnosis of *** The sera of 23 patients with AS-related transient ischaemic attack were screened by serological identification of antigens through recombinant cDNA expression cloning(SEREX),and cDNA clones were *** function enrichment analysis was performed on cDNA clones to identify their biological pathways and determine whether they were related to AS or ***,gene–gene and protein–protein interactions were performed and AS-associated markers would be *** expression of AS biomarkers in human normal organs and pan-cancer tumour tissues were ***,immune infiltration level and tumour mutation burden of various immune cells were *** curves analysis could show the expression of AS markers in *** AS-related sera were screened by SEREX,and 83 cDNA clones with high homology were *** functional enrichment analysis,it was found that their functions were closely related to AS and tumour *** multiple biological information interaction screening and the external cohort validating,poly(A)binding protein cytoplasmic 1(PABPC1)was found to be a potential AS *** assess whether PABPC1 was related to pan-cancer,its expression in different tumour pathological stages and ages was *** AS-associated proteins were closely related to cancer immune infiltration,we investigated and found that PABPC1 had the same role in ***,analysis of Kaplan-Meier survival curves revealed that high PABPC1 expression in pan-cancer was associated with high risk of *** Through the findings of SEREX and bioinformatics pan-cancer analysis,we concluded that PABPC1 might serve as a potential biomarker for the

关键词： diagnosis cancer organs

Orthogroup and phylotranscriptomic analyses identify transcription factors involved in the plant cold response:Acase study of Arabidopsis BBX29

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Plant Communications 2023年第6期4卷 148-162页

作者： Shuo Wang Yirong shen Deyin Deng Liangyu Guo yixian Zhang Yuqi Nie Yunfei Du Xijuan Zhao Xiaoxue Ye Jianqin Huang Huahong Huang Jian-Kang Zhu Wenwu Wu State Key Laboratory of Subtropical Silviculture Zhejiang A&F UniversityLin’an 311300HangzhouChina Institute of Tropical Biosciences and Biotechnology Chinese Academy of Tropical Agricultural SciencesHaikou 571101China Institute of Advanced Biotechnology and School of Life Sciences Southern University of Science and TechnologyShenzhen 518055China Center for Advanced Bioindustry Technologies Chinese Academy of Agricultural SciencesBeijing 100081China

C-repeat binding factors(CBFs)are well-known transcription factors(TFs)that regulate plant cold *** sequencing(RNA-seq)data from diverse plant species provide opportunities to identify other TFs involved in the cold ***,this task is challenging because gene gain and loss has led to an intertwined community of co-orthologs and in-paralogs between and within *** orthogroup(closely related homologs)analysis,we identified 10,549 orthogroups in five representative eudicots.A phylotranscriptomic analysis of cold-treated seedlings from eudicots identified 35 high-confidence conserved cold-responsive transcription factor orthogroups(CoCoFos).These 35 CoCoFos included the well-known cold-responsive regulators CBFs,HSFC1,ZAT6/10,and CZF1 among *** used Arabidopsis BBX29 for experimental *** and genetic analyses showed that cold-induction of BBX29 is CBF-and abscisic acid-independent,and BBX29 is a negative regulator of cold *** RNA-seq and Cleavage Under Targets and Tagmentation followed by sequencing analyses revealed that BBX29 represses a set of cold-induced TFs(ZAT12,PRR9,RVE1,MYB96,etc.).Altogether,our analysis yielded a library of eudicot CoCoFos and demonstrated that BBX29 is a negative regulator of cold tolerance in Arabidopsis.

关键词： phylogenomics phylotranscriptomics orthogroup cold acclimation BBX29 CBF-independent pathway