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生物制剂治疗银屑病患者出现严重感染的风险评估:一项系统性回顾与荟萃分析
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皮肤性病诊疗学杂志 2017年 第3期24卷 224-224页
作者: yiu zz Exton LS Jabbar-Lopez Z Mohd Mustapa MF Samarasekera EJ Burden AD Murphy R Owen CM Parslew R Venning V Ashcroft DM Griffiths CE Smith CH Warren RB 薛如君 张锡宝 Dermatology Centre Salford Royal NHS Foundation Trust The University of Manchester Manchester Academic Health Science Centre Manchester UK Centre for Pharmacoepidemiology and Drug Safety Manchester Pharmacy School The University of Manchester Manchester UK. British Association of Dermatologists London UK. Department of Dermatology Royal Victoria Infirmary Newcastle upon Tyne Hospitals NHS Foundation Trust Newcastle UK. National Clinical Guideline Centre Royal College of Physicians of London London UK. Department of Dermatology Western Infirmary Glasgow UK. Sheffield University Teaching Hospitals and Sheffield Children's Hospitals Sheffield UK. Department of Dermatology East Lancashire Hospitals NHS Trust Royal Blackburn Hospital Blackburn Lancashire UK. Department of Dermatology Royal Liverpool and Broadgreen University Hospitals Trust Liverpool UK. Department of Dermatology Oxford University Hospitals Foundation Trust Oxford UK. Centre for Pharmacoepidemiology and Drug Safety Manchester Pharmacy School The University of Manchester Manchester UK. Dermatology Centre Salford Royal NHS Foundation Trust The University of Manchester Manchester Academic Health Science Centre Manchester UK. St John's Institute of Dermatology Guy's and St. Thomas' NHS Foundation Trust London UK. Electronic address: catherine.smith@kcl.ac.uk. Dermatology Centre Salford Royal NHS Foundation Trust The University of Manchester Manchester Academic Health Science Centre Manchester UK. Electronic address: richard.warren@manchester.ac.uk.
肿瘤坏死因子抑制剂英夫利昔单抗、依那西普和阿达木单抗是目前用于治疗银屑病常用的3种生物制剂,新药优特克单抗是IL-12和IL-23拮抗剂,苏金单抗是IL-17受体拮抗剂。生物制剂通过抑制细胞因子,调控银屑病患者紊乱的免疫系统,从而发... 详细信息
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