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Multi-surrogate framework with an adaptive selection mechanism for production optimization

Petroleum Science 2024年第1期21卷 366-383页

作者： Jia-Lin Wang Li-Ming Zhang Kai Zhang Jian Wang Jian-ping Zhou Wen-Feng Peng Fa-Liang Yin Chao Zhong Xia Yan pi-Yang Liu Hua-Qing Zhang Yong-Fei Yang Hai Sun School of Petroleum Engineering China University of Petroleum(East China)Qingdao266580ShandongChina Qingdao University of Technology Qingdao266580ShandongChina College of Science China University of PetroleumQingdao266580ShandongChina Zepu Oil and Gas Development Department PetroChina Tarim Oilfield CompanyKorla841000XinjiangChina Hainan Branch of CNOOC Ltd Haikou70311HainanChina

Data-driven surrogate models that assist with efficient evolutionary algorithms to find the optimal development scheme have been widely used to solve reservoir production optimization ***,existing research suggests that the effectiveness of a surrogate model can vary depending on the complexity of the design problem.A surrogate model that has demonstrated success in one scenario may not perform as well in *** the absence of prior knowledge,finding a promising surrogate model that performs well for an unknown reservoir is ***,the optimization process often relies on a single evolutionary algorithm,which can yield varying results across different *** address these limitations,this paper introduces a novel approach called the multi-surrogate framework with an adaptive selection mechanism(MSFASM)to tackle production optimization *** consists of two *** the first stage,a reduced-dimensional broad learning system(BLS)is used to adaptively select the evolutionary algorithm with the best performance during the current optimization *** the second stage,the multi-objective algorithm,non-dominated sorting genetic algorithm II(NSGA-II),is used as an optimizer to find a set of Pareto solutions with good performance on multiple surrogate models.A novel optimal point criterion is utilized in this stage to select the Pareto solutions,thereby obtaining the desired development schemes without increasing the computational load of the numerical *** two stages are combined using sequential transfer *** the two most important perspectives of an evolutionary algorithm and a surrogate model,the proposed method improves adaptability to optimization problems of various reservoir *** verify the effectiveness of the proposed method,four 100-dimensional benchmark functions and two reservoir models are tested,and the results are compared with those obtained by six other surrogate-model-based *** res

关键词： Production optimization Multi-surrogate models Multi-evolutionary algorithms Dimension reduction Broad learning system

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Endoscopic-ultrasound-guided biliary drainage with placement of electrocautery-enhanced lumen-apposing metal stent for palliation of malignant biliary obstruction:Updated meta-analysis

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World Journal of Gastrointestinal Surgery 2024年第3期16卷 907-920页

作者： Zu-Xiang Peng Fang-Fang Chen Wen Tang Xu Zeng Hong-Juan Du Ru-Xian pi Hong-Ming Liu Xiao-Xiao Lu Department of Hepatobiliary Surgery Daping HospitalArmy Medical UniversityChongqing 400042China Department of Oncology Chongqing General HospitalChongqing UniversityChongqing 401147China Department of Gastroenterology and Hepatobiliary Surgery People’s Hospital of Fenggang CountyGuizhou 564200Guizhou ProvinceChina Hepatobiliary and Pancreatic Tumor Center Chongqing University Cancer HospitalChongqing 400030China

BACKGROUND Endoscopic ultrasound-guided biliary drainage using electrocautery-enhanced(ECE)delivery of lumen-apposing metal stent(LAMS)is gradually being re-cognized as a viable palliative technique for malignant biliary obstruction after endoscopic retrograde cholangiopancreatography(ERCP)***,most of the studies that have assessed its efficacy and safety were small and *** meta-analyses of six or fewer studies that were published 2 years ago were therefore underpowered to yield convincing *** To update the efficacy and safety of ECE-LAMS for treatment of biliary ob-struction after ERCP *** We searched PubMed,EMBASE,and Scopus databases from the inception of the ECE technique to May 13,*** outcome measure was pooled technical success rate,and secondary outcomes were pooled rates of clinical success,re-intervention,and adverse ***-analysis was performed using a random-effects model following Freeman-Tukey double-arcsine transformation in R soft-ware(version 4.1.3).RESULTS Fourteen eligible studies involving 620 participants were ultimately *** pooled rate of technical success was 96.7%,and clinical success was 91.0%.Adverse events were reported in 17.5%of *** reinter-vention rate was 7.3%.Subgroup analyses showed results were generally *** ECE-LAMS has favorable success with acceptable adverse events in relieving biliary obstruction when ERCP is *** consistency of results across most subgroups suggested that this is a generalizable approach.

关键词： Biliary obstruction Biliary drainage Electrocautery-enhanced lumen-apposing metal stents Endoscopic ultrasound Endoscopic retrograde cholangiopancreatography failure

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合理设计安全仪表功能回路的冗余架构

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炼油技术与工程 2024年第1期54卷 27-30,45页

作者：皮宇中石化广州工程有限公司广东省广州市510620

安全仪表功能(SIF)回路的冗余架构应满足安全和误停车率的要求。结合安全完整性等级(SIL)验证工作的经验,对影响SIF冗余架构设计的标准及各种规定的强制约束和影响SIF回路冗余架构设计的因素,如:安全失效因子、平均失效率及误停车率、... 详细信息

安全仪表功能(SIF)回路的冗余架构应满足安全和误停车率的要求。结合安全完整性等级(SIL)验证工作的经验,对影响SIF冗余架构设计的标准及各种规定的强制约束和影响SIF回路冗余架构设计的因素,如:安全失效因子、平均失效率及误停车率、共因失效及检验测试时间间隔、仪表测量及制造原理、仪表故障模式对架构降级的约束等,进行了工程分析,给出了合理的冗余架构设计原则。合理的冗余架构设计,应当兼顾SIF回路中的各个部件,并非冗余仪表越多越好,也并非越少越好,在经济条件允许的前提下,合理性是在满足安全及减少误停车率之间平衡的结果。

关键词：安全仪表功能冗余架构安全失效因子平均失效率误停车率共因失效检验测试时间间隔仪表故障模式

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DNA Methylation Variation Is Identified in Monozygotic Twins Discordant for Congenital Heart Diseases

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Congenital Heart Disease 2024年第2期19卷 247-256页

作者： Shuliang Xia Huikang Tao Shixin Su Xinxin Chen Li Ma Jianru Li Bei Gao Xumei Liu Lei pi Jinqing Feng Fengxiang Li Jia Li Zhiwei Zhang Guangdong Provincial People’s Hospital Southern Medical UniversityGuangzhou510100China Department of Cardiovascular Surgery Guangzhou Women and Children’s Medical CenterGuangzhou Medical UniversityGuangdong Provincial Clinical Research Center for Child HealthGuangzhou510623China Department of Pediatric Cardiology Guangdong Cardiovascular InstituteGuangdong Provincial Key Laboratory of South China Structural Heart DiseaseGuangzhou510100China Clinical Physiology Laboratory Institute of PediatricsGuangzhou Women and Children’s Medical CenterGuangzhou Medical UniversityGuangdong Provincial Key Laboratory of Research in Structural Birth Defect DiseaseGuangzhou510623China Department of Echocardiogram Guangzhou Women and Children’s Medical CenterGuangzhou Medical UniversityGuangdong Provincial Clinical Research Center for Child HealthGuangzhou510623China Department of Pediatrics Washington University School of MedicineSt.LouisMO63130USA Clinical Biological Resource Bank of Guangzhou Women and Children’s Medical Center Guangzhou Medical UniversityGuangzhou510623China

Aims:Multiple genes and environmental factors are known to be involved in congenital heart disease(CHD),but epigenetic variation has received little ***(MZ)twins with CHD provide a unique model for exploring this *** order to investigate the potential role of Deoxyribonucleic Acid(DNA)methyla-tion in CHD pathogenesis,the present study examined DNA methylation variation in MZ twins discordant for CHD,especially ventricular septal defect(VSD).Methods and Results:Using genome-wide DNA methylation profiles,we identified 4004 differentially methylated regions(DMRs)in 18 MZ twin pairs discordant for CHD,and 2826 genes were *** Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)analysis revealed a list of CHD-associated *** further investigate the role of DNA methylation in VSD,data from 7 pairs of MZ twins with VSD were *** identified 1614 DMRs corresponding to 1443 genes associated with arrhythmogenic right ventricular cardiomyopathy,cyclic guanosine monopho-sphate-protein kinase G(cGMP-PKG)signaling pathway by KEGG analysis,and cell-cell adhesion,calcium ion transmembrane transport by GO analysis.A proportion of DMR-associated genes were involved in calcium signaling *** methylation changes of calcium signaling genes might be related to VSD ***:CHD is associated with differential DNA methylation in MZ *** may be etiologically linked to DNA methylation,and methylation of calcium signaling genes may be involved in the development of VSD.

关键词： Congenital heart disease monozygotic twins methylation modification epigenetics

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从《教学通义》白的内在困境看康有为的经学转向

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哲学动态 2024年第4期 34-41页

作者：皮迷迷首都师范大学哲学系

康有为从以《教学通义》为代表的古文经学立场转向以“两考”为标志的今文经学立场,前人多将之归因于廖平的影响和康有为上书清帝失败等外部因素。然而,以《教学通义》中的内在困境为线索,可以看到,此种转变自有其内在动因,即康有为对... 详细信息

康有为从以《教学通义》为代表的古文经学立场转向以“两考”为标志的今文经学立场,前人多将之归因于廖平的影响和康有为上书清帝失败等外部因素。然而,以《教学通义》中的内在困境为线索,可以看到,此种转变自有其内在动因,即康有为对建立一个完整、统一经学体系的诉求。由于廖平的“二变”处理了经学中周公、孔子的矛盾,帮助康有为克服了他在《教学通义》中的理论困境,实现了经学体系的一统。因此,康有为果断接受了廖平“二变”中以古学为刘歆所伪的结论,实现了他的经学转向。

关键词：康有为廖平《教学通义》经学转向

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Ⅰ型神经纤维瘤病诊治进展及展望

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中国修复重建外科杂志 2024年第10期38卷 1166-1170页

作者：刘丕楠首都医科大学附属北京天坛医院神经外科北京100070

Ⅰ型神经纤维瘤病(neurofibromatosis type 1,NF1)是一种由NF1基因突变引起的常染色体显性遗传疾病,以神经纤维瘤为主要疾病特征,同时影响神经、皮肤和骨骼等多个系统,具有复杂的临床表现。自1988年美国国立卫生研究院(NIH)制定诊断标... 详细信息

Ⅰ型神经纤维瘤病(neurofibromatosis type 1,NF1)是一种由NF1基因突变引起的常染色体显性遗传疾病,以神经纤维瘤为主要疾病特征,同时影响神经、皮肤和骨骼等多个系统,具有复杂的临床表现。自1988年美国国立卫生研究院(NIH)制定诊断标准以来,NF1的诊断和治疗取得了显著进展。然而,由于疾病的复杂性和有效治疗方法的欠缺,NF1的诊治仍面临诸多挑战。加强多学科协作,完善并普及疾病的诊治策略,研发更有效的药物和治疗方法是进一步提高NF1疾病治疗水平的关键。

关键词： Ⅰ型神经纤维瘤病多学科诊断治疗临床研究

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Anisotropic etching mechanisms of 4H-SiC:Experimental and first-principles insights

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Journal of Semiconductors 2024年第1期45卷 42-47页

作者： Guang Yang Lingbo Xu Can Cui Xiaodong pi Deren Yang Rong Wang Key Laboratory of Optical Field Manipulation of Zhejiang Province Department of PhysicsZhejiang Sci-Tech UniversityHangzhou 310018China State Key Laboratory of Silicon and Advanced Semiconductor Materials&School of Materials Science and Engineering Zhejiang UniversityHangzhou 310027China Institute of Advanced Semiconductors&Zhejiang Provincial Key Laboratory of Power Semiconductor Materials and Devices HangzhoIun novation CenterZhejiang UniversityHangzhou 311200China

Molten-alkali etching has been widely used to reveal dislocations in 4H silicon carbide(4H-SiC),which has promoted the identification and statistics of dislocation density in 4H-SiC single ***,the etching mechanism of 4H-SiC is limited *** this letter,we reveal the anisotropic etching mechanism of the Si face and C face of 4H-SiC by combining molten-KOH etching,X-ray photoelectron spectroscopy(XPS)and first-principles *** activation energies for the molten-KOH etching of the C face and Si face of 4H-SiC are calculated to be 25.09 and 35.75 kcal/mol,*** molten-KOH etching rate of the C face is higher than the Si *** XPS analysis and first-principles calculations,we find that the molten-KOH etching of 4H-SiC is proceeded by the cycling of the oxidation of 4H-SiC by the dissolved oxygen and the removal of oxides by molten *** faster etching rate of the C face is caused by the fact that the oxides on the C face are unstable,and easier to be removed with molten alkali,rather than the C face being easier to be oxidized.

关键词： principles alkali etching

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Effect of fractures on mechanical behavior of sand powder 3D printing rock analogue under triaxial compression

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Journal of Central South University 2024年第8期31卷 2703-2716页

作者： Li, pi-mao Jiang, Li-shuai Wen, Zhi-jie Wu, Chao-lei Yang, Yi-ming Peng, Xiao-han Wu, Quan-sen Wu, Quan-lin State Key Laboratory of Mining Disaster Prevention and Control Shandong University of Science and Technology Qingdao China Mining College Guizhou University Guiyang China School of Engineering Jining University Qufu China

In practical engineering applications, rock mass are often found to be subjected to a triaxial stress state. Concurrently, defects like joints and fractures have a notable impact on the mechanical behavior of rock mass. Such defects are identified as crucial contributors to the failure and instability of the surrounding rock, subsequently impacting the engineering stability. The study aimed to investigate the impact of fracture geometry and confining pressure on the deformation, failure characteristics, and strength of specimens using sand powder 3D printing technology and conventional triaxial compression tests. The results indicate that the number of fractures present considerably influences the peak strength, axial peak strain and elastic modulus of the specimens. Confining pressure is an important factor affecting the failure pattern of the specimen, under which the specimen is more prone to shear failure, but the initiation, expansion and penetration processes of secondary cracks in different fracture specimens are different. This study confirmed the feasibility of using sand powder 3D printing specimens as soft rock analogs for triaxial compression research. The insights from this research are deemed essential for a deeper understanding of the mechanical behavior of fractured surrounding rocks when under triaxial stress state.

关键词： confining pressure fracture geometry mechanical behavior sand powder 3D printing triaxial compression

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城市轨道交通车辆智能运维系统信息安全技术方案

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城市轨道交通研究 2024年第6期27卷 281-285页

作者：皮魏株洲中车时代电气股份有限公司株洲412001

[目的]随着城市轨道交通规模迅猛增长,车辆运维信息化和智能化应用日趋广泛,城市轨道交通车辆智能运维系统的信息安全问题逐渐凸显和亟待解决。[方法]基于城市轨道交通车辆智能运维系统可能面临的软件漏洞、系统性防护缺失、网络传输安... 详细信息

[目的]随着城市轨道交通规模迅猛增长,车辆运维信息化和智能化应用日趋广泛,城市轨道交通车辆智能运维系统的信息安全问题逐渐凸显和亟待解决。[方法]基于城市轨道交通车辆智能运维系统可能面临的软件漏洞、系统性防护缺失、网络传输安全等诸多信息安全风险和问题,参考多项国家和行业的信息安全标准,体系化地提出了安全分区、边界隔离、纵向认证、集中监管的信息安全防护技术方案。通过软件加固、访问控制、安全审计、入侵防范保护设备主机的安全;通过车载、车地、地面各通信网络之间的安全分区、边界隔离、安全传输、鲁棒网络保护网络传输的安全;通过管控保护业务数据的存储、传输、应用、销毁各环节提高其安全性;通过身份认证、会话管理、访问控制、安全审计、入侵防范保护应用平台的安全;通过分权管理和集中管控实现全系统的安全管理中心。[结果及结论]构筑的信息安全防护技术体系具备系统性、统一性、全面性,避免车辆智能运维系统遭受恶意攻击和非法入侵,保护系统安全性,从而实现安全、高效、可靠的城市轨道交通车辆运维。

关键词：城市轨道交通车辆智能运维信息安全

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中国式发展道路的福利效应

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中国经济问题 2024年第1期 121-135页

作者：皮建才张鹏清南京大学经济学院广东外语外贸大学经济贸易学院

本文通过构建包含政治晋升锦标赛机制的多部门动态随机一般均衡模型,以中国特色的垂直结构下国有企业在国民经济中的作用为切入点,研究“有效市场+有为政府”的中国式发展道路的福利效应。我们的研究发现:政治晋升冲击对社会福利的影响... 详细信息

本文通过构建包含政治晋升锦标赛机制的多部门动态随机一般均衡模型,以中国特色的垂直结构下国有企业在国民经济中的作用为切入点,研究“有效市场+有为政府”的中国式发展道路的福利效应。我们的研究发现:政治晋升冲击对社会福利的影响呈U型变化,上下游关联程度冲击会降低社会福利,淡化GDP考核并弱化上下游关联程度则有利于提高社会福利;推进金融改革,降低非国有企业部门的融资约束,可以提升社会福利;但是,如果政府部门退出对国有企业的适当支持,并不能很好发挥“有为政府”的作用,反而有损社会福利。因此,在中国式发展道路中,我们需要充分考虑我国的政治晋升锦标赛和垂直结构所发挥的作用。

关键词：中国式发展道路福利效应政治晋升锦标赛垂直结构

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