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Journal of Iron and Steel Research International 2024年第8期31卷 1900-1913页

作者： jin-wen Song Wen Yan Zhe Chen ying Liu Shao-song Hong The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan 430081HubeiChina National-provincial Joint Engineering Research Center of High Temperature Materials and Lining Technology Wuhan University of Science and TechnologyWuhan 430081HubeiChina Jiangsu Sheng Nai New Materials Co. Ltd.Taizhou 225503JiangsuChina

The effect of nano-carbon black content(O,8 and 12 wt.%)on the wettability of molten steel on Al_(2)O_(3)-C substrates was investigated by the sessile drop wetting method at 1500℃ under argon *** the beginning of the wetting experiment,the contact angle decreased with the increase in nano-carbon black *** the wetting experiment progressed,FeAl_(2)0_(4) layer and sheet Al_(2)O_(3) layer were found at the interface between the molten steel and the Al_(2)O_(3)-C substrates with O and 8 wt.% nano-carbon black content,and the contact angle deceased with *** the content of nano-carbon black was 12 wt.%,a large number of nano-Al_(2)O_(3) whiskers were observed,which made the contact angle between the molten steel and Al_(2)O_(3)-C substrate become *** on the scanning electron microscope and energy dispersive spectrometry results,the formation mechanism of FeAl2O4 layer and Al_(2)O_(3) layer and the interfacial reaction mechanism were proposed.

关键词： Contact angle Nano-carbon black Al_(2)O_(3)-C substrate Molten steel Interfacial reaction

Improvement of mechanical properties and investigation of strengthening mechanisms on the Ti_(3)AlC_(2) ceramic with nanosized WC addition

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Journal of Advanced Ceramics 2024年第6期13卷 861-876页

作者： Yi Zhong ying Liu Qinkai Jiang Na jin Zifeng Lin jinwen Ye School of Materials Science&Engineering Sichuan UniversityChengdu 610065China Yibin R&D Park Yibin Industrial Technology Research InstituteSichuan UniversityYibin 644005China

Ti_(3)AlC_(2) (TAC) has great potential for use as an ablation material in aerospace applications due to its great oxidation/ablation resistance, but its high-temperature strength and thermal shock resistance still have much room for simultaneous improvement under fast temperature variation conditions. Herein, we used Ti_(3)AlC_(2) and WC powders as raw materials and successfully fabricated textured (Ti,W)_(3)AlC_(2) ceramic with small amounts of TiC and Al_(2)O_(3), and room temperature mechanical properties such as flexural strength (1146±46.9 MPa), fracture toughness (11.78±0.44 MPa·m^(1/2)), and hardness (5.81±0.11 GPa) at 5 wt% WC addition were achieved. The high-temperature strength of the ceramic was significantly improved, and better thermal shock resistance from 298 to 1173 K was simultaneously acquired together with the regulation of the elastic modulus, thermal conductivity, and thermal expansion coefficient, providing (Ti,W)_(3)AlC_(2) with more possibilities for fast-temperature variation applications. Strengthening and toughening mechanisms were proposed. Scanning transmission electron microscopy high-angle annular dark-field imaging (STEM-HADDF) showed that W randomly replaced the Ti1 and Ti2 sites of Ti_(3)AlC_(2), providing a good reference for establishing crystal models, and further density functional theory (DFT) calculations based on these models indicated a higher fracture energy of (Ti,W)_(3)AlC_(2) along different crystal planes, providing superior resistance to transgranular fracture;a lower mismatch degree of (Ti,W)_(3)AlC_(2)/Al_(2)O_(3) resulted in stronger interface bonding, resulting in greater resistance to intergranular fracture as well as more balanced stress distributions at different interfaces.

关键词： mechanical properties solid solution MAX phase transmission electron microscopy(TEM) ceramic atomic structure

Characterization of Electrical Tree Degradation of Epoxy Resin under Thermal and Temperature Stresses by Photoelastic Effect

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Chinese Journal of Electrical Engineering 2024年第1期10卷 12-20页

作者： Hein Htet Aung Yuhuai Wang jin Li ying Zhang Tatsuo Takada School of Electrical and Information Engineering Tianjin UniversityTianjin 300072China Department of Power Generation and Transformation Engineering Baoding Technical College of Electric PowerBaoding 071051China Measurement and Electric Machine Control Laboratory Tokyo City UniversityTokyo 158-8557Japan

Epoxy resin is widely used in the support,insulation,and packaging components of electrical equipment owing to their excellent insulation,thermal,and mechanical ***,epoxy-resin insulation often suffers from thermal and mechanical stresses under extreme environmental conditions and a compact design,which can induce electrical tree degradation and insulation failure in electrical *** this study,the photoelastic method is employed to investigate the thermal-mechanical coupling stress dependence of the electrical treeing behavior of epoxy *** electrical tree growth morphology and stress distribution were observed using the photoelastic *** correlation between the tree length and overall accumulated damage with an increase in mechanical stress is *** results show that compressive stress retards the growth of electrical trees along the electric field,while tensile stress has accelerating *** proves that the presence of thermal stress can induce more severe accumulated damage.

关键词： Epoxy resin electrical tree degradation thermal stress mechanical stress photoelastic effects

Implantable Electrochemical Microsensors for In Vivo Monitoring of Animal Physiological Information

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Nano-Micro Letters 2024年第3期16卷 183-211页

作者： jin Zhou Shenghan Zhou Peidi Fan Xunjia Li Yibin ying Jianfeng Ping Yuxiang Pan Laboratory of Agricultural Information Intelligent Sensing College of Biosystems Engineering and Food ScienceZhejiang UniversityHangzhou 310058People’s Republic of China ZJU-Hangzhou Global Scientific and Technological Innovation Center Zhejiang UniversityHangzhou 311200People’s Republic of China

In vivo monitoring of animal physiological information plays a crucial role in promptly alerting humans to potential diseases in animals and aiding in the exploration of mechanisms underlying human ***,implantable electrochemical microsensors have emerged as a prominent area of *** microsensors not only fulfill the technical requirements for monitoring animal physiological information but also offer an ideal platform for *** have been extensively studied for their ability to monitor animal physiological information in a minimally invasive manner,characterized by their bloodless,painless features,and exceptional *** development of implantable electrochemical microsensors for in vivo monitoring of animal physiological information has witnessed significant scientific and technological advancements through dedicated *** review commenced with a comprehensive discussion of the construction of microsensors,including the materials utilized and the methods employed for *** this,we proceeded to explore the various implantation technologies employed for electrochemical *** addition,a comprehensive overview was provided of the various applications of implantable electrochemical microsensors,specifically in the monitoring of diseases and the investigation of disease ***,a concise conclusion was conducted on the recent advancements and significant obstacles pertaining to the practical implementation of implantable electrochemical microsensors.

关键词： Electrochemical microsensors Implantable sensors In vivo monitoring Animal physiological information

Dynamic access task scheduling of LEO constellation based on space-based distributed computing

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Journal of Systems Engineering and Electronics 2024年第4期35卷 842-854页

作者： LIU Wei jin Yifeng ZHANG Lei GAO Zihe TAO ying Institute of Telecommunication and Navigation Satellites China Academy of Space TechnologyBeijing 100094China Innovation Center of Satellite Communication System China National Space AdministrationBeijing 100094China

A dynamic multi-beam resource allocation algorithm for large low Earth orbit(LEO)constellation based on on-board distributed computing is proposed in this *** allocation is a combinatorial optimization process under a series of complex constraints,which is important for enhancing the matching between resources and requirements.A complex algorithm is not available because that the LEO on-board resources is *** proposed genetic algorithm(GA)based on two-dimen-sional individual model and uncorrelated single paternal inheri-tance method is designed to support distributed computation to enhance the feasibility of on-board application.A distributed system composed of eight embedded devices is built to verify the algorithm.A typical scenario is built in the system to evalu-ate the resource allocation process,algorithm mathematical model,trigger strategy,and distributed computation *** to the simulation and measurement results,the proposed algorithm can provide an allocation result for more than 1500 tasks in 14 s and the success rate is more than 91%in a typical *** response time is decreased by 40%com-pared with the conditional GA.

关键词： beam resource allocation distributed computing low Earth obbit(LEO)constellation spacecraft access task scheduling

Transcriptome-based analysis of key signaling pathways affecting the formation of primordial germ cell in chickens

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Journal of Integrative Agriculture 2024年第5期23卷 1644-1657页

作者： ying Ding Qiong Zhi Qisheng Zuo Kai jin Wei Han Bichun Li Key Laboratory of Animal Genetics Breeding and Molecular Design of Jiangsu ProvinceCollege of Animal Science and TechnologyYangzhou UniversityYangzhou 225009China Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China Yangzhou UniversityYangzhou225009China Poultry Research Institute Chinese Academy of Agricultural Sciences/Jiangsu Institute of Poultry ScienceYangzhou 225009China

Bone morphogenetic protein 4(BMP4)can induce the formation of chicken primordial germ cells(PGCs)in vitro;however,its regulatory mechanism in poultry remains *** study aimed to use RNA-seq to analyze PGCs in chicken embryos and iPGCs induced by BMP4 in vitro,clarify the internal regulatory factors of PGCs,analyze the mechanism of the formation of PGCs,and lay a theoretical foundation for the further optimization of PGCs induction *** stem cells(ESCs),PGCs and iPGCs induced by BMP4 in vitro were *** transcriptional maps of the three cell types were studied using *** results showed 6,142 genes differentially expressed between PGCs and iPGCs,of which 2,728 were upregulated in iPGCs and 3,414 were downregulated in *** to that in ESCs,BMP4 was significantly upregulated in PGCs and *** results showed that both the TGF-βand Wnt signaling pathways were activated during the formation of PGCs in vitro and in vivo,and the activation was more significant during iPGCs induced by *** expression of Nodal,an inhibitory factor of TGF-βsignaling,was significantly decreased in PGCs and iPGCs,but was not expressed in iPGCs,which further supports our ***,the Lysosome and PI3K-AKT signaling pathways were significantly enriched in PGCs and iPGCs,***,transmission electron microscopy(TEM)results showed that the number of autolysosomes was significantly higher after the addition of BMP4,which is consistent with the KEGG ***,the number of PGCs was significantly reduced after ATG14 was interfered in vivo and in *** conclusion,this study screened out the key signaling pathways during the formation of PGCs,aiming to provide help for enriching the mechanism network regulating PGCs formation in chicken and laying a theoretical foundation for further improving the efficiency of inducing PGCs in vitro.

关键词： RNA-seq BMP4 PGCs ATG14 chicken

Effective integration of highly-efficient focusing apodized grating and quantum dots on a solid substrate for scalable quantum photonic circuits

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Science China(Physics,Mechanics & Astronomy) 2024年第9期67卷 99-107页

作者： Beimeng Yao Rongbin Su Shunfa Liu Changkun Song ying Yu jin Liu Xuehua Wang State Key Laboratory of Optoelectronic Materials and Technologies School of PhysicsSun Yat-sen UniversityGuangzhou 510275China State Key Laboratory of Optoelectronic Materials and Technologies School of Electronics and Information TechnologySun Yat-sen UniversityGuangzhou 510275China

Recent advancements in quantum photonic circuits have significantly influenced the field of quantum information *** pursuit of an integrated quantum photonic circuit that offers an active,stable platform for large-scale integration and high processing efficiency remains a key *** grating coupler,as a crucial element for an efficient transformation output interface in the integrated quantum photonic circuits,presents significant potential for practical ***,we demonstrate the integration block of a highly efficient shallow-etched focusing apodized grating coupler with indium arsenide(InAs)quantum dots(QDs)in gallium arsenide(GaAs)on a SiO2substrate for active quantum photonic *** designed grating couplers possess a high efficiency over 90% in the broadband(900-930 nm)from the circuit to free space,and a nearly-perfect match with the fiber ***,the efficiency to free space reaches 81.8%,and the match degree with the fiber mode is high up to 92.1%.The proposed integration block offers the potential for large-scale integration of active quantum photonic circuits due to its stable solid substrate and highly performant output for quantum measurements.

关键词： quantum dot grating coupler wafer bonding quantum photonic circuit

CALTM:A Context-Aware Long-Term Time-Series Forecasting Model

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Computer Modeling in Engineering & Sciences 2024年第4期139卷 873-891页

作者： Canghong jin Jiapeng Chen Shuyu Wu Hao Wu Shuoping Wang jing ying School of Computer and Computing Science Hangzhou City UniversityHangzhou310015China School of Computer Science and Engineering Macao University of Science and TechnologyMacao999078China College of Computer Science and Technology Zhejiang UniversityHangzhou310058China

Time series data plays a crucial role in intelligent transportation *** flow forecasting represents a precise estimation of future traffic flow within a specific region and time *** approaches,including sequence periodic,regression,and deep learning models,have shown promising results in short-term series ***,forecasting scenarios specifically focused on holiday traffic flow present unique challenges,such as distinct traffic patterns during vacations and the increased demand for long-term ***,the effectiveness of existing methods diminishes in such ***,we propose a novel longterm forecasting model based on scene matching and embedding fusion representation to forecast long-term holiday traffic *** model comprises three components:the similar scene matching module,responsible for extracting Similar Scene Features;the long-short term representation fusion module,which integrates scenario embeddings;and a simple fully connected layer at the head for making the final *** results on real datasets demonstrate that our model outperforms other methods,particularly in medium and long-term forecasting scenarios.

关键词： Traffic volume forecasting scene matching multi module fusion

Organic Integration of Traditional Chinese and Western Medicines—Future of Clinical Practice Guidelines of Integrated Traditional Chinese and Western Medicines

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Chinese Journal of Integrative Medicine 2024年第4期30卷 359-365页

作者： XIE ying-lan HAN Fei jin ying-hui DING Yan-bing GUO jing JI Dong-xiao ZHANG Teng CHENXiao-min SHANG Hong-cai Department of Traditional Chinese Medicine Encephalopathy Hubei Provincial Hospital of Traditional Chinese MedicineWuhan(430074)China Department of Traditional Chinese Medicine Encephalopathy Hubei Province Traditional Chinese Medicine Research InstituteWuhan(430074)China Xuanwu Hospital of Traditional Chinese Medicine Beijing(100000)China Center for Evidence-Based and Translational Medicine Zhongnan Hospital of Wuhan UniversityWuhan(430074)China College of Acupuncture and Massage College of Health and RehabilitationNanjing University of Chinese MedicineNanjing(210023)China Department of Ophthalmology Huaihe Hospital of Henan UniversityKaifengHenan Province(475000)China Ministry of Education and Beijing Key Laboratory of Internal Medicine of Traditional Chinese Medicine Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine/Ministry of Education and Beijing Key Laboratory of Internal Medicine of Traditional Chinese MedicineBeijing(100700)China

The transformation and implementation of clinical practice guidelines for integrated traditional Chinese medicine(TCM)and Western medicine(WM)is crucial to the adoption of medical science and technological findings and is an important way for TCM to be made available to the ***,clinical practice guidelines(CPGs)of TCM and WM integration in recent years was analyzed to clarify the current situation and problems in the existing guidelines according to the following four perspectives:(1)perspective of TCM and WM integration in guidelines,(2)diagnosis Using integrated TCM and WM,(3)integration of TCM and WM treatment,(4)promoting TCM and WM ***,the information and quality evaluation of CPGs for integrated Chinese and Western medicine in 2020–2022 were analyzed to explore the degree and methods of integration of Chinese and Western medicine *** last this study aimed to lay a foundation for the further establishment of Chinese characteristic,repeatable,and calculable clinical practice guidelines of TCM and WM integration.

关键词： clinical practice guidelines integrated traditional Chinese and Western medicine organic integration

Anti-epileptic and Neuroprotective Effects of Ultra-low Dose NADPH Oxidase Inhibitor Dextromethorphan on Kainic Acid-induced Chronic Temporal Lobe Epilepsy in Rats

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Neuroscience Bulletin 2024年第5期40卷 577-593页

作者： jing-jing Yang ying-Xin Liu Yan-Fang Wang Bi-ying Ge ying Wang Qing-Shan Wang Sheng Li Jian-Jie Zhang Ling-Ling jin Jau-Shyong Hong Sheng-Ming Yin Jie Zhao College of Basic Medical Sciences Dalian Medical UniversityDalian116044China Department of Neurology The First Affiliated Hospital of Dalian Medical UniversityDalian116011China National and Local Joint Engineering Research Center for Drug Research and Development of Neurodegenerative Diseases Dalian116044China School of Public Health Dalian Medical UniversityDalian116044China Neurobiology Laboratory National Institute of Environmental Health SciencesNational Institutes of HealthResearch Triangle ParkDurhamNC27709USA

Neuroinflammation mediated by microglia and oxidative stress play pivotal roles in the development of chronic temporal lobe epilepsy(TLE).We postulated that kainic acid(KA)-Induced status epilepticus triggers microglia-dependent inflammation,leading to neuronal damage,a lowered seizure threshold,and the emergence of spontaneous recurrent seizures(SRS).Extensive evidence from our laboratory suggests that dextromethorphan(DM),even in ultra-low doses,has anti-inflammatory and neuroprotective effects in many animal models of neurodegenerative *** results showed that administration of DM(10 ng/kg per day;subcutaneously via osmotic minipump for 4 weeks)significantly mitigated the residual effects of KA,including the frequency of SRS and seizure *** addition,DM-treated rats showed improved cognitive function and reduced hippocampal neuronal *** found suppressed microglial activation-mediated neuroinflammation and decreased expression of hippocampal gp91^(phox) and p47^(phox) proteins in KA-induced chronic TLE ***,even after discontinuation of DM treatment,ultra-low doses of DM continued to confer long-term anti-seizure and neuroprotective effects,which were attributed to the inhibition of microglial NADPH oxidase 2 as revealed by mechanistic studies.

关键词： Temporal lobe epilepsy Dextromethorphan NADPH oxidase Ultra-low dose