检索结果-南通市图书馆

Liver transplantation for liver failure in kidney transplantation recipients with hepatitis B virus infection

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2021年第1期20卷 94-98页

作者： Peng-Peng Zhang Xing-Guo She Ke Cheng Hong Liu ying Niu ying-zi ming Transplantation Center Third Xiangya HospitalCentral South UniversityChangsha 410013China Engineering&Technology Research Center for Transplantation Medicine of National Ministry of Health Changsha 410013China

To the Editor:Worldwide,approximately 400 million patients have chronic hepatitis B virus(HBV)infection[1].Because of the high incidence of HBV in China,the incidence of HBV infection in uremia and kidney transplantation(KTx)patients is 2.5%and 2.7%,respectively[2].Since the first successful organ transplant conducted between twins in 1954,refined surgical techniques,improved immunosuppressive protocols,and improved perioperative management of transplant patients have resulted in improved patient and graft survivals following K Tx[3].However,the K Tx community is now challenged with liver failure due to the increased risk of HBV viral activation and replication induced by immunosuppressive *** et al.[4]highlighted that KTx recipients with HBV infection had lower 5-year survival(61%)than patients on dialysis(85%).Although these KTx recipients were treated with regular anti-HBV therapy,the incidence of liver failure was increased in KTx patients with HBV ***,isolated liver transplantation(LTx),sequential liver and kidney transplantation(SLKT),and combined liver and kidney transplantation(CLKT)are the optimal treatments for patients with liver failure and hepatorenal syndrome[5].However,the outcomes of KTx recipients following isolated LTx,SLKT or CLKT for HBV-associated liver failure remain to be ***,we report our experience in ten HBV-positive KTx recipients with liver failure undergoing LTx.

关键词： infection kidney liver

Severe and delayed immune-mediated hemolysis post-liver transplantation

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2017年第6期16卷 665-668页

作者： Quan Zhuang Hong Liu Ke Cheng ying Niu Xing-Guo She ying-zi ming Transplantation Center of the Third Xiangya Hospital Central South University Changsha 410013 China

To the Editor:Hemolysis,which is caused by a variety of immune and non-immune mechanisms,is a well-recognized complication of solid organ transplantation.;Hemolysis post-liver transplantation can be induced by drug,in... 详细信息

关键词： RBC Severe and delayed immune-mediated hemolysis post-liver transplantation PLS DCD EBV

Detecting chimerism contributes to diagnosis of graft versus host disease after orthotopic liver transplantation

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2018年第4期17卷 363-366页

作者： Bo Peng Hong Liu Quan Zhuang Ke Cheng ying-zi ming Transplantation Center of the Third Xiangya Hospital Central South UniversityChangsha 410013China Engineering Technology Research Center for Transplantation Medicine of National Ministry of Health Changsha 410013China

To the Editor:Graft versus host disease(GVHD)occurs when the immunocompetent cells from the donor mount an immune response against the tissues of the host[1].It is commonly seen in the patients who received hematopoie... 详细信息

关键词： OLT POD

Orthotopic liver transplantation from a donor with Schistosoma japonicum

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2017年第3期16卷 326-328页

作者： Bo Peng Xing-Guo She Ke Cheng Hong Liu ying Niu ying-zi ming The Transplantation Center of the Third Xiangya Hospital Central South University Changsha 410013 China Engineering & Technology Research Center for Transplantation Medicine of National Ministry of Health Changsha 410013 China

To the Editor：Despite of the rapid increase of donation after cardiac death （DCD） in China, the shortage of organs continues to be a major problem. Every organ procured is so valuable that it should never be discarded easily, especially a liver that could save a patient＇s life in an emergency. This leads to the use of grafts from donors with unrecognized Here and unusual diseases, including schistosomiasis. we reported a case of orthotopic liver transplantation （OLT） from a donor with Schistosorna japonicurn to a patient with end-stage cirrhosis due to HBV infection.

关键词： from on is Orthotopic liver transplantation from a donor with Schistosoma japonicum with of

Hepatic veins anatomy and piggy-back liver transplantation

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2012年第4期11卷 429-433页

作者： ying-zi ming,ying Niu,ming-Jie Shao,Xing-Guo She and Qi-Fa Ye Research Center of Chinese Health Ministry on Transplantation Medicine Engineering and Technology,The Third Xiangya Hospital,Central South University,Changsha 410013,China Research Center of Chinese Health Ministry on Transplantation Medicine Engineering and Technology The Third Xiangya Hospital Central South University Changsha 410013 China

BACKGROUND:The piggy-back caval anastomosis technique is widely used in orthotopic liver transplantation although it carries an increased risk of complications,including outflow obstruction and Budd-Chiari *** aim of this study is to clarify the anatomy and variations of hepatic veins(HVs) draining into the inferior vena cava(IVC),and to classify the surgical techniques of piggy-back liver transplantation(PBLT) based on the anatomy of HVs which can reduce the occurrence of ***:PBLT was performed in 248 consecutive cases at our hospital from January 2004 to August *** anatomy of recipients’ HVs was determined when removing the native diseased *** anatomy of HVs and short HVs draining into the IVC were *** data were collected and ***:We classified anatomic variations of HVs in the 248 livers into five types according to the way of drainage into the IVC:type I(trunk type of left and middle HVs),142(57.3%) patients;type II(trunk type of right and middle HVs),54(21.8%);type III(trunk type of left,middle and right HVs),14(5.6%);type IV(non-trunk type of left,middle and right HVs),of which,type IVa,16(6.5%),in the same horizontal plane;type IVb,18(7.3%),in different horizontal planes;and type V(segment type),4(1.6%).The patients whose HVs anatomy belonged to types I,II and III underwent classical piggy-back liver *** IVa patients had classical PBLT via HV venoplasty prior to piggy-back anastomosis,while type IVb patients and type V patients could only have modified ***:This study demonstrates that HVs can be classified according to the anatomy of their drainage into the IVC and we can use this classification to choose the best operative approach to PBLT.

关键词： hepatic vein classification piggy-back liver transplantation

The gut microbiome modulate response to immunotherapy in cancer

在线全文

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2025年第2期68卷 381-396页

作者： Shan-Shan Jiang zi-Ran Kang ying-Xuan Chen Jing-Yuan Fang Division of Gastroenterologyand Hepatology Shanghai Instituteof Digestive DiseaseNHC KeyLaboratoryof Digestive DiseasesState KeyLaboratoryfor Oncogenesand Related GenesRenji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200001China

Gut microbiota have been reported to play an important role in the occurrence and development of malignant ***,clinical studies have identified specific gut microbiota and its metabolites associated with efficacy of immunotherapy in multiple types of *** investigations have elucidated that gut microbiota modulate the antitumor immunity and affect the efficacy of cancer *** microbiota and its metabolites may favorably remodel the tumor microenvironment by engaging innate and/or adaptive immune *** how the gut microbiome interacts with cancer immunotherapy opens new avenues for improving treatment *** microbial transplants,probiotics,dietary interventions,and other strategies targeting the microbiota have shown promise in preclinical studies to enhance the *** clinical trials are evaluating these *** review presents the recent advancements in understanding the dynamic interplay among the host immunity,the microbiome,and cancer immunotherapy,as well as strategies for modulating the microbiome,with a view to translating into clinical applications.

关键词： cancer immunotherapy gut microbiota intratumoral microbiota microbiota-derived metabolites innate and adaptive immunity

Deciphering fungal metabolon coupling tandem inverse-electrondemand Diels-Alder reaction and semipinacol rearrangement for the biosynthesis of spiro polycyclic alkaloids

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2025年第1期68卷 288-296页

作者： Shuai Liu Wen-Qiang Xu ying-Tong Di Man-Cheng Tang Ding-Kang Chen ming-ming Cao Yao-Wen Chang Hong-Yu Tang Chun-Mao Yuan Jun-Bo Yang Zhi-Li Zuo Han Guo zi-Fei Xu ying Zeng Yun-Dong Wu Xiao-Jiang Hao Key Laboratory of Phytochemistry and Natural Medicines(Chinese Academy of Sciences) Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China Lab of Computational Chemistry and Drug Design State Key Laboratory of Chemical OncogenomicsPeking University Shenzhen Graduate SchoolShenzhen 518055China Shenzhen Bay Laboratory Shenzhen 518055China University of Chinese Academy of Sciences Beijing 100049China State Key Laboratory of Microbial Metabolism School of Life Sciences&BiotechnologyShanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical UniversityGuiyang 550014China Molecular Biology Experimental Center Germplasm Bank of Wild Species in Southwest ChinaKunming Institute of BotanyChinese Academy of SciencesKunming 650201China Yunnan Key Laboratory for Wild Plant Resources Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China Research Unit of Chemical Biology of Natural Anti-Virus Products Chinese Academy of Medical SciencesBeijing 100730China

In the intricate process of natural product biosynthesis,a metabolon can enhance metabolic flux by associating sequential enzymes.A fungal metabolon,comprising of flavin-dependent monooxygenase Spe F and P450 monooxygenase Spe G,is identified in the biosynthesis of spiro polycyclic alkaloids(+)-notoamide B and its diastereomer(+)-versicolamide *** notoamide E as a substance,Spe F/Spe G metabolon can control the stereoselectivity of its 2,3-epoxidation,followed by hydrogen atom ion at C-17 to generate reactive epoxide tau-m A with dienyl iminium ***,(+)-notoamide B and(+)-versicolamide B are produced via tandem nonenzymatic inverse-electron-demand Diels-Alder reaction and semipinacol *** provides the first example of metabolon in the biosynthesis of spiro-prenylated indole alkaloids.

关键词： metabolon Diels-Alder reaction semipinacol rearrangement biosynthesis notoamides spiro polycyclic alkaloids

New classification of gastric polyps:An in-depth analysis and critical evaluation

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第7期31卷 149-155页

作者： Xiao-Hui Liao ying-ming Sun Hong-Bin Chen Department of Gastroenterology The First Hospital of Sanming Affiliated to Fujian Medical UniversityFujian Medical UniversitySanming 365000Fujian ProvinceChina Department of Medical and Radiation Oncology Sanming First HospitalFujian Medical UniversitySanming 365000Fujian ProvinceChina Department of Gastroenterology I Sanming First HospitalFujian Medical UniversitySanming 365000Fujian ProvinceChina

With the widespread use of upper gastrointestinal endoscopy,more and more gastric polyps(GPs)are being *** management strategies often rely on histopathologic examination,which can be time-consuming and may not guide immediate clinical *** paper aims to introduce a novel classification system for GPs based on their potential risk of malignant transformation,categorizing them as"good","bad",and"ugly".A review of the literature and clinical case analysis were conducted to explore the clinical implications,management strategies,and the system's application in endoscopic *** polyps,mainly including fundic gland polyps and inflammatory fibrous polyps,have a low risk of malignancy and typically require minimal or no *** polyps,mainly including hyperplastic polyps and adenomas,pose an intermediate risk of malignancy,necessitating closer monitoring or *** polyps,mainly including type 3 neuroendocrine tumors and early gastric cancer,indicate a high potential for malignancy and require urgent and comprehensive *** new classification system provides a simplified and practical framework for diagnosing and managing GPs,improving diagnostic accuracy,guiding individualized treatment,and promoting advancements in endoscopic *** some challenges,such as the risk of misclassification due to similar endoscopic appearances,this system is essential for the standardized management of *** also lays the foundation for future research into biomarkers and the development of personalized medicine.

关键词： Gastric polyps Classification Fundic gland polyps Inflammatory fibroid polyps Hyperplastic polyps Adenomas Neuroendocrine tumors Early gastric cancer Patient management

Improved reference-frame-independent quantum key distribution with intensity fluctuations

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2025年第2期34卷 48-52页

作者： zi-Qi Chen Hao-Bing Sun ming-Shuo Sun Qin Wang Institute of Quantum Information and Technology Nanjing University of Posts and TelecommunicationsNanjing 210003China Broadband Wireless Communication and Sensor Network Technology Key Laboratory of Ministry of EducationNanjing University of Posts and TelecommunicationsNanjing 210003China

Reference-frame-independent quantum key distribution(RFI-QKD) can avoid real-time calibration operation of reference frames and improve the efficiency of the communication process. However, due to imperfections of optical devices,there will inevitably exist intensity fluctuations in the source side of the QKD system, which will affect the final secure key rate. To reduce the influence of intensity fluctuations, an improved 3-intensity RFI-QKD scheme is proposed in this *** considering statistical fluctuations and implementing global parameter optimization, we conduct corresponding simulation analysis. The results show that our present work can present both higher key rate and a farther transmission distance than the standard method.

关键词： quantum key distribution intensity fluctuations decoy-state method