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Progress of environmental research in China from 2000 to 2019: Case studies of JES and ES&T

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Journal of Environmental Sciences 2022年第6期34卷 139-141页

作者： Rongrong Lei ying xing Wenbin Liu Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China Institutes of Science and Development Chinese Academy of SciencesBeijing 100190China Hangzhou Institute For Advanced Study UCASHangzhou 310024China

China’s tremendous economic and cultural progress since the initiation of the reforms and opening up process has been accompanied by the steady expansion of its scientific research *** selected Journal of Environmental Sciences and Environmental Science&Technology(hereinafter referred to as JES and ES&T,respectively)as two representative journals for assessing the progress and impact of research in the field of environmental science in China.

关键词： reforms tremendous assessing

Synthesis and characterization of miktoarm star copolymer of styrene and butadiene using multifunctional macromolecular initiator

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Chinese Chemical Letters 2009年第9期20卷 1131-1135页

作者： Hai Yan Zhang xing ying Zhang Key Laboratory on Preparation and Processing of Novel Polymer Materials Beijing University of Chemical Technology Beijing 100029 China

A new kind of multifunctional macromolecular initiator with Sn-C bonds and polydiene arms was synthesized by living anionic polymerization. At first, polydiene-stannum chloride （PD-SnCl3） was prepared by the reaction of n-butyl-Li （n-BuLi）, stannic chloride （SnCl4） and diene. Then PD-SnCl3 was used to react with the dilithium initiator to prepare the multifunctional organic macromolecular initiators. The result suggested that the initiators had a remarkable yield by GPC, nearly 90%. By using these multifunctional macromolecular initiators, styrene and butadiene were effectively polymefized via anionic polymerization, which gave birth to novel miktoarm star copolymers. The relative molecular weight and polydispersity index, microstructure contents, copolymerization components, glass transition temperature （Tg） and morphology of the miktoarm star copolymers were investigated by GPC-UV, ~H NMR, DSC and TEM, respectively. 2009 xing ying Zhang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： Mnitifunctional macromolecular initiator Miktoarm star copolymer Styrene Butadiene Isoprene Anionic polymerization

Effect and mechanism of β-L-D4A on DNA polymerase α

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World Journal of Gastroenterology 2007年第46期13卷 6243-6248页

作者： Yan Li Ju-Sheng Lin ying-Hui Zhang Xiao-Yan Wang ying Chang xing-xing He Institute of Liver Diseases Tongji MedicalCollege Huazhong University of Science and Technology 1095Jiefang Street Wuhan 430030 Hubei Province China

AIM： To investigate the safety of β-L-D4A on DNA polymerase α.METHODS： Ion exchange chromatography was used to separate DNA polymerase cc from crude extract of human Hela cells. Detailed kinetic parameters were determined for β-L-D4A against DNA polymeraseα . RESULTS： DNA polymerase was purified with 4% yield and 31000 units/mg specific activity. The Michaelis constant （Km = 3.22 i^mol/L）, 50% inhibition concentration （IC50 = 178.49 μmol/L） and inhibition constant （Ki = 126 mol/L） of β-L-D4A were determined by kinetic analysis. CONCLUSION： β-L-D4A is a more safe nucleoside for hepatitis B virus （HBV） infection with a lower host toxicity.

关键词： Nucleoside β-L-D4A DNA polymeraseα Kinetic study Side effect Hepatitis B virus

Multi-objective test case prioritization based on multi-population cooperative particle swarm optimization

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The Journal of China Universities of Posts and Telecommunications 2020年第1期27卷 38-50页

作者： Wang Hongman Li Jinzhong xing ying Zhou Xiaoguang Institute of Network Technology Beijing University of Posts and TelecommunicationsBeijing 100876China School of Automation Beijing University of Posts and TelecommunicationsBeijing 100876China Information Networks Engineering Research Center Ministry of EducationBeijing 100876China

Test case prioritization(TCP) technique is an efficient approach to improve regression testing activities. With the continuous improvement of industrial testing requirements, traditional single-objective TCP is limited greatly, and multi-objective test case prioritization(MOTCP) technique becomes one of the hot topics in the field of software testing in recent years. Considering the problems of traditional genetic algorithm(GA) and swarm intelligence algorithm in solving MOTCP problems, such as falling into local optimum quickly and weak stability of the algorithm, a MOTCP algorithm based on multi-population cooperative particle swarm optimization(MPPSO) was proposed in this paper. Empirical studies were conducted to study the influence of iteration times on the proposed MOTCP algorithm, and compare the performances of MOTCP based on single-population particle swarm optimization(PSO) and MOTCP based on non-dominated sorting genetic algorithm Ⅱ(NSGA-Ⅱ) with the MOTCP algorithm proposed in this paper. The results of experiments show that the TCP algorithm based on MPPSO has stronger global optimization ability, is not easy to fall into local optimum, and can solve the MOTCP problem better than TCP algorithm based on the single-population PSO and NSGA-Ⅱ.

关键词： regression testing test case prioritization multi-population cooperative particle swarm optimization multi-objective optimization

Reconstructing Equation of State for Dark Energy in Double Complex Symmetric Gravitational Theory

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Communications in Theoretical Physics 2007年第6期47卷 1148-1152页

作者： SHAO ying GUI Yuan-xing WANG Wei Department of Physics Dalian University of Technology Dalian 116023 China

We propose to study the accelerating expansion of the universe in the double complex symmetric gravitational theory （DCSGT）. The universe we live in is taken as the real part of the whole spacetime MC^4（J）, which is double complex. By introducing the spatially flat FRW metric, not only the double Friedmann equations but also the two constraint conditions py = 0 and J^2 = 1 are obtained. Farthermore, using parametric DL（z） ansatz, we reconstruct the ω/（z） and V（Ф） for dark energy from real observational data. We find that in the two cases of J = i, pJ = 0, and J = ε, pJ≠0, the corresponding equations of state ω＇（z） remain close to -1 at present （z = 0） and change from below -1 to above -1. The results illustrate that the whole spacetime, i.e. the double complex spacetime MC^4（J）, may be either ordinary complex （J = i, pJ = 0） or hyperbolic complex （J = ε, pJ≠ 0）. And the fate of the universe would be Big Rip in the future.

关键词： double complex symmetric gravitational theory equation of state dark energy

Two outward potassium current types are expressed during the neural differentiation of neural stem cells

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Neural Regeneration Research 2013年第28期8卷 2656-2665页

作者： Ruiying Bai Guowei Gao ying xing Hong Xue Department of Physiology and Neurobiology Xinxiang Medical University Department of Radiotherapy Center Hospital of Xinxiang Stem Cell Research Center Zhengzhou University Basic Medical Sciences of Henan University of Traditional Chinese Medicine

The electrophysiological properties of potassium ion channels are regarded as a basic index for determining the functional differentiation of neural stem cells. In this study, neural stem cells from the hippocampus of newborn rats were induced to differentiate with neurotrophic growth factor, and the electrophysiological properties of the voltage-gated potassium ion channels were observed. Immunofluorescence staining showed that the rapidly proliferating neural stem cells formed spheres in vitro that expressed high levels of nestin. The differentiated neurons were shown to express neuron-specific enolase. Flow cytometric analysis revealed that the neural stem cells were actively dividing and the percentage of cells in the S ＋ G2/M phase was high. However, the ratio of cells in the S ＋ G2/M phase decreased obviously as differentiation proceeded. Whole-cell patch-clamp re- cordings revealed apparent changes in potassium ion currents as the neurons differentiated. The potassium ion currents consisted of one transient outward potassium ion current and one delayed rectifier potassium ion current, which were blocked by 4-aminopyridine and tetraethylammonium, respectively. The experimental findings indicate that neural stem cells from newborn rat hippo- campus could be cultured and induced to differentiate into functional neurons under defined condi- tions in vitro. The differentiated neurons expressed two types of outward potassium ion cur＇ents similar to those of mature neurons in vivo.

关键词： neural regeneration neural stem cells hippocampus proliferation differentiation neurons patch-clamp electrophysiological properties transient outward potassium ion current delayed rec-tifier potassium ion current inactivation nestin neuron-specific enolase grants-supported paper neuroregeneration

Direct evidence of high temperature superconductivity in one-unit-cell FeSe films on SrTiO_3 substrate by transport and magnetization measurements

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Chinese Physics B 2015年第11期24卷 15-22页

作者：邢颖王健 International Center for Quantum Materials School of Physics Peking University Collaborative Innovation Center of Quantum Matter

Zero resistance and Meissner effect are two crucial experimental evidences of superconductivity in determining a new kind of superconductor, which can be detected by transport and diamagnetic measurements. In this paper, we briefly review the main transport and magnetization results on the one unit cell （1-UC） FeSe films grown on SrTiO3 （STO） substrates from our team in recent years, which identify the high temperature superconductivity in 1-UC FeSe films.

关键词： two-dimensional superconductivity one-unit-cell FeSe transport measurement diamagnetic prop-erty

A multiscale adaptive framework based on convolutional neural network:Application to fluid catalytic cracking product yield prediction

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Petroleum Science 2024年第4期21卷 2849-2869页

作者： Nan Liu Chun-Meng Zhu Meng-Xuan Zhang xing-ying Lan College of Artificial Intelligence China University of Petroleum(Beijing)Beijing102249China State Key Laboratory of Heavy Oil Processing China University of Petroleum(Beijing)Beijing102249China

Since chemical processes are highly non-linear and multiscale,it is vital to deeply mine the multiscale coupling relationships embedded in the massive process data for the prediction and anomaly tracing of crucial process parameters and production *** the integrated method of adaptive signal decomposition combined with time series models could effectively predict process variables,it does have limitations in capturing the high-frequency detail of the operation state when applied to complex chemical *** light of this,a novel Multiscale Multi-radius Multi-step Convolutional Neural Network(Msrt Net)is proposed for mining spatiotemporal multiscale ***,the industrial data from the Fluid Catalytic Cracking(FCC)process decomposition using Complete Ensemble Empirical Mode Decomposition with Adaptive Noise(CEEMDAN)extract the multi-energy scale information of the feature ***,convolution kernels with varying stride and padding structures are established to decouple the long-period operation process information encapsulated within the multi-energy scale ***,a reconciliation network is trained to reconstruct the multiscale prediction results and obtain the final *** Net is initially assessed for its capability to untangle the spatiotemporal multiscale relationships among variables in the Tennessee Eastman Process(TEP).Subsequently,the performance of Msrt Net is evaluated in predicting product yield for a 2.80×10^(6) t/a FCC unit,taking diesel and gasoline yield as *** conclusion,Msrt Net can decouple and effectively extract spatiotemporal multiscale information from chemical process data and achieve a approximately reduction of 30%in prediction error compared to other time-series ***,its robustness and transferability underscore its promising potential for broader applications.

关键词： Fluid catalytic cracking Product yield Data-driven modeling Multiscale prediction Data decomposition Convolution neural network

Increased expression of receptor for advanced glycation end-products worsens focal brain ischemia in diabetic rats

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Neural Regeneration Research 2012年第13期7卷 1000-1005页

作者： ying xing Jinting He Weidong Yu Lingling Hou Jiajun Chen China-Japan Union Hospital Jilin University Changchun 130033 Jilin Province China

A rat model of diabetes mellitus was induced by a high fat diet, followed by focal brain ischemia induced using the thread method after 0.5 month. Immunohistochemistry showed that expression of receptor for advanced glycation end-products was higher in the ischemic cortex of diabetic rats compared with non-diabetic rats with brain ischemia. Western blot assay revealed increased phosphorylated c-Jun N-terminal kinase expression, and unchanged phosphorylated extracellular signal-regulated protein kinase protein expression in the ischemic cortex of diabetic rats compared with non-diabetic rats with brain ischemia. Additionally, phosphorylated p38 mitogen-activated protein kinase protein was not detected in any rats in the two groups. Severity of limb hemiplegia was worse in diabetic rats with brain ischemia compared with ischemia alone rats. The results suggest that increased expression of receptor for advanced glycation end-products can further activate the c-Jun N-terminal kinase pathway in mitogen-activated protein kinase, thereby worsening brain injury associated with focal brain ischemia in diabetic rats.

关键词： receptor for advanced glycation end-products focal brain ischemia diabetes mellitus mitogen-activated protein kinase c-Jun N-terminal kinase signal transduction neural regeneration