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深冷处理对Al_(1.2)CrFe_(2)Ni_(2)高熵合金组织和性能的影响

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铸造 2024年第4期73卷 469-475页

作者：谢思晨张伟齐浩李广龙李荣德曲迎东沈阳工业大学材料科学与工程学院辽宁沈阳110870 辽宁省高校轻金属材料与工程重点试验室辽宁沈阳110870

采用非自耗真空电弧熔炼炉制备了Al_(1.2)CrFe_(2)Ni_(2)高熵合金,利用液氮对其进行了不同时间的深冷处理,分析了深冷处理时间对该合金微观组织和性能的影响。结果表明:随着深冷处理时间的延长,Al_(1.2)CrFe_(2)Ni_(2)高熵合金的晶粒尺... 详细信息

采用非自耗真空电弧熔炼炉制备了Al_(1.2)CrFe_(2)Ni_(2)高熵合金,利用液氮对其进行了不同时间的深冷处理,分析了深冷处理时间对该合金微观组织和性能的影响。结果表明:随着深冷处理时间的延长,Al_(1.2)CrFe_(2)Ni_(2)高熵合金的晶粒尺寸先减小后增大,合金晶界处析出B2纳米相,其体积分数呈现先增加后减小的趋势。深冷处理对Al_(1.2)CrFe_(2)Ni_(2)高熵合金具有细晶强化和沉淀强化的作用。当深冷时间为24 h时,合金的硬度、压缩屈服强度和摩擦磨损性能均达到最大值,其硬度和屈服强度分别为HV 607.5和1 259.9 MPa,相比于铸态合金分别提升了18.7%和5.2%,其平均摩擦系数由铸态合金的0.89减小至0.66。

关键词：高熵合金深冷处理压缩性能维氏硬度摩擦磨损性能

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中高能重离子束全径迹辐照材料和细胞的实验装置设计及效应分析

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广东化工 2024年第7期51卷 1-3,16页

作者：李兴林曲颖孙曙光天津科技大学天津300457 中国科学院近代物理研究所甘肃兰州730000 安徽思母塘生物技术发展有限公司安徽马鞍山243000

中高能重离子束注入生物材料的径迹显著深于生物靶,且不同径迹点上的剂量分布、理化效应等又大不相同,所以,同一靶点通常不可能接受所有理化因子的作用(即全径迹辐照)。本实验设计思路:基于CR-39核径迹探测手段,在纯水介质中验证全径迹... 详细信息

中高能重离子束注入生物材料的径迹显著深于生物靶,且不同径迹点上的剂量分布、理化效应等又大不相同,所以,同一靶点通常不可能接受所有理化因子的作用(即全径迹辐照)。本实验设计思路:基于CR-39核径迹探测手段,在纯水介质中验证全径迹辐照综合效应特征;通过沿径迹上连续逆向移动靶材料或细胞培养液,以探究全径迹的辐照效应。最后,与对照组相比较,揭示重离子束全径迹的辐照效应及其潜在的分子改性、细胞改良和发酵工程等方面的应用价值。

关键词：重离子束全径迹辐照材料细胞装置设计效应分析

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电容去离子技术去除水中硝酸盐的研究进展

工业水处理 2024年第7期44卷 29-37页

作者：房金峰曲莹赵玉博刘汝鹏张震齐震樊浩宇朱炜臣山东建筑大学市政与环境工程学院山东济南250101 济南水务集团有限公司山东济南250013 山东建筑大学资源与环境创新研究院山东济南250101

电容去离子技术(Capacitive deionization,CDI)是一种新兴的电化学硝酸盐脱除技术,具有结构和操作简单、成本低、能耗低、对环境友好等优点,但存在吸附容量不足、选择性较差、脱盐能力有限等问题。针对CDI存在的问题,国内外学者在CDI装... 详细信息

电容去离子技术(Capacitive deionization,CDI)是一种新兴的电化学硝酸盐脱除技术,具有结构和操作简单、成本低、能耗低、对环境友好等优点,但存在吸附容量不足、选择性较差、脱盐能力有限等问题。针对CDI存在的问题,国内外学者在CDI装置结构优化及电极材料改性方面进行了深入研究。介绍了CDI装置在膜电容去离子技术(MCDI)、流动电极电容去离子技术(FCDI)、电容-电催化耦合技术等结构优化方面的研究进展。电极材料改性研究进展主要从树脂类涂覆、表面改性、金属氧化物/氢氧化物掺杂、结构调控等方面进行了介绍。通过CDI装置结构优化和电极材料改性,提高了电容去离子技术去除硝酸盐的性能,扩大了其去除硝酸盐的适用范围,使得电容去离子技术在去除硝酸盐方面有十分广阔的应用前景。最后针对提高选择性与去除率、提高电极吸附容量、增强电极可持续利用性、实际应用等方面提出相应建议,以期为CDI的进一步发展提供参考。

关键词：电容去离子技术电极改性结构优化硝酸盐

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高血压患者体质类型与认知障碍相关性研究

山东中医杂志 2024年第6期43卷 590-597页

作者：曲颖钟霞吕顺新焦华琛山东中医药大学山东济南250355 山东中医药大学附属医院山东济南250011

目的:探讨高血压伴认知障碍(CI)患者的体质分布情况及CI的影响因素。方法:纳入3799例高血压患者,分为CI组和无认知障碍(NCI)组,记录两组患者一般资料(年龄、性别、文化程度、婚姻状态、工作类型、烟酒史等)、实验室指标(空腹血糖、血脂... 详细信息

目的:探讨高血压伴认知障碍(CI)患者的体质分布情况及CI的影响因素。方法:纳入3799例高血压患者,分为CI组和无认知障碍(NCI)组,记录两组患者一般资料(年龄、性别、文化程度、婚姻状态、工作类型、烟酒史等)、实验室指标(空腹血糖、血脂、血肌酐等)水平、量表[简易智力状态检查量表(MMSE)、匹兹堡睡眠质量指数量表(PSQI)、中医体质类型量表]评分等信息。以体质类型为主要监测指标,分析高血压伴CI患者体质类型分布状况。结果:3799例高血压患者中有506例(13.32%)被纳入CI组。CI组患者年龄、年龄大于60岁人群比例、女性比例、文化程度在初中以下人群比例、工作类型以体力劳动为主人群比例、3级高血压人群比例、有睡眠障碍人群比例、高血压病程、血肌酐水平显著高于NCI组(P<0.05);汉族人群比例、吸烟人群比例、饮酒人群比例、体质量指数(BMI)及甘油三酯、胆固醇、低密度脂蛋白(LDL)水平低于NCI组(P<0.05)。CI组气虚质患者人数最多,NCI组平和质患者人数最多。偏颇质高血压患者的定向、记忆、计算、回忆、命名、阅读、执行、书写认知功能比平和质高血压患者更差(P<0.05)。Logistic回归分析显示,体质类型是CI发病的影响因素,气虚质、气郁质与CI发生相关。年龄大于60岁、文化程度低、汉族以外的其他民族、存在睡眠障碍、LDL水平低与CI发生有关。结论:不同中医体质的高血压患者CI发病倾向不同,气虚质、气郁质与CI发生相关,此类体质者应从“体病相关”理论出发,采取相应预防措施。

关键词：高血压认知障碍体质体病相关气虚质气郁质 Logistic回归分析

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Frequency‐to‐spectrum mapping GAN for semisupervised hyperspectral anomaly detection

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CAAI Transactions on Intelligence Technology 2023年第4期8卷 1258-1273页

作者： Degang Wang Lianru Gao ying qu Xu Sun Wenzhi Liao Key Laboratory of Computational Optical Imaging Technology Aerospace Information Research InstituteChinese Academy of SciencesBeijingChina College of Resources and Environment University of Chinese Academy of SciencesBeijingChina Faculty of Geographical Science Beijing Normal UniversityBeijingChina Flanders Make LommelBelgium Ghent University GhentBelgium

Most unsupervised or semisupervised hyperspectral anomaly detection(HAD)methods train background reconstruction models in the original spectral ***,due to the noise and spatial resolution limitations,there may be a lack of discrimination between backgrounds and *** makes it easy for the autoencoder to capture the lowlevel features shared between the two,thereby increasing the difficulty of separating anomalies from the backgrounds,which runs counter to the purpose of *** this end,the authors map the original spectrums to the fractional Fourier domain(FrFD)and reformulate it as a mapping task in which restoration errors are employed to distinguish background and *** study proposes a novel frequency‐to‐spectrum mapping generative adversarial network for ***,the depth separable features of backgrounds and anomalies are enhanced in the *** to the semisupervised approach,FTSGAN needs to learn the embedded features of the backgrounds,thus mapping and restoring them from the FrFD to the original spectral *** strategy effectively prevents the model from focussing on the numerical equivalence of input and output,and restricts the ability of FTSGAN to restore *** comparison and analysis of the experiments verify that the proposed method is competitive.

关键词： deep learning generative adversarial network hyperspectral image neural network semisupervised learning

Parallel Integrated Model-Driven and Data-Driven Online Transient Stability Assessment Method for Power System

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Energy Engineering 2023年第11期120卷 2585-2609页

作者： ying Zhang Xiaoqing Han Chao Zhang ying qu Yang Liu Gengwu Zhang Electric Power Research Institute State Grid Shanxi Electric Power Co.Ltd.Taiyuan030000China College of Electrical and Power Engineering Taiyuan University of TechnologyTaiyuan030024China

More and more uncertain factors in power systems and more and more complex operation modes of power systems put forward higher requirements for online transient stability assessment *** traditional modeldriven methods have clear physical mechanisms and reliable evaluation results but the calculation process is time-consuming,while the data-driven methods have the strong fitting ability and fast calculation speed but the evaluation results lack ***,it is a future development trend of transient stability assessment methods to combine these two kinds of *** this paper,the rate of change of the kinetic energy method is used to calculate the transient stability in the model-driven stage,and the support vector machine and extreme learning machine with different internal principles are respectively used to predict the transient stability in the data-driven *** order to quantify the credibility level of the data-driven methods,the credibility index of the output results is *** the switching function controlling whether the rate of change of the kinetic energy method is activated or not is established based on this ***,a newparallel integratedmodel-driven and datadriven online transient stability assessment method is *** accuracy,efficiency,and adaptability of the proposed method are verified by numerical examples.

关键词： Rate of change of kinetic energy support vectormachine extreme learning machine credibility index model-data parallel integration

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46例猫肥厚性心肌病的超声心动图临床分析

畜牧与兽医 2024年第7期56卷 117-123页

作者：瞿颖柳雨桐曹万迪李帅范小丽周振雷南京农业大学动物医学院江苏南京210095

肥厚性心肌病(HCM)是猫最常见的一种心肌病,家猫的发病率约为15%。心脏超声检查是HCM早期诊断最为准确的工具,可直接检测左心室壁是否存在增厚情况,并且提供心脏形态、瓣膜运动状态、心内血流情况等信息。本研究对46例猫HCM案例的超声... 详细信息

肥厚性心肌病(HCM)是猫最常见的一种心肌病,家猫的发病率约为15%。心脏超声检查是HCM早期诊断最为准确的工具,可直接检测左心室壁是否存在增厚情况,并且提供心脏形态、瓣膜运动状态、心内血流情况等信息。本研究对46例猫HCM案例的超声心动参数进行了统计学分析,结果显示:舒张末期左心室后壁厚度(LVPW-d)、舒张末期室间隔厚度(IVS-d)、收缩末期左心室后壁厚度(LVPW-s)、收缩末期室间隔厚度(IVS-s)和左心房/主动脉比值(LA/AO)这5项参数在健康组、亚临床组和发病组之间存在显著差异(P<0.01),各项超声心动参数不受猫的年龄和性别影响;而以LVPW-d、IVS-d、LA/AO这3项参数建立的Logistic回归模型可以准确地对疾病进行诊断和分期。本研究表明,LVPW-d、IVS-d、LA/AO参数对于确诊猫肥厚性心肌病有重要参考价值。

关键词：肥厚型心肌病超声心动参数猫

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Differential amplification method for flow structures analysis of centrifugal pump between design and off-design points

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Journal of Central South University 2017年第6期24卷 1443-1449页

作者： ZHANG He-hui DENG Sheng-xiang qu ying-jie School of Energy Science and Engineering Central South UniversityChangsha 410083China Hunan M&W Energy Saving Tech.Co.Ltd. Changsha 410208China

The three-dimensional internal flow field of centrifugal pump is complex and variable with design parameters and operation conditions. The post-processing technique named differential amplification method was proposed for the comparison study of different flow structures. The full steady flow fields of an industrial centrifugal pump working on-design and off-design points were numerically investigated by solving Reynolds average Navier-Stokes equations together with a shear-stress transport(SST) k-? turbulence model. And the numerically predicted performance curves of the studied pump agree well with test measurement results. Compared with the flow flied on design point under the help of differential amplification method, the disturbance caused by interaction between blade and volute tongue is very obvious and it extends to the diffuser pipe on the working point with 0.8 times rated flux. While on the point with 1.2 times rated flux, the flow distribution in impeller region is roughly even and it flows more to the bottom section of the diffuser pipe. The above method was proved to be good at displaying the subtle secondary flow structure changes with a higher resolution effect relative to single isolated case observation, which helps the optimization decision-making from multiple design cases.

关键词： differential amplification computational fluid dynamics (CFD) flow structure centrifugal pump

Novel matrine derivative MD-1 attenuates hepatic fibrosis by inhibiting EGFR activation of hepatic stellate cells

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Protein & Cell 2016年第9期7卷 662-672页

作者： Yi Feng Hai-yan ying ying qu Xiao-bo Cai Ming-yi Xu Lun-gen Lu Department of Gastroenterology Shanghai General Hospital Nanjing Medical University Shanghai 200080 China

Matrine （MT）, the effective component of Sophora fla- vescens Air, has been shown to have anti-inflammation, immune-suppressive, anti-tumor, and anti-hepatic fibrosis activities. However, the pharmacological effects of MT still need to be strengthened due to its relatively low efficacy and short half-life. In the present study, we report a more effective thio derivative of MT, MD-1, and its inhibitory effects on the activation of hepatic stellate cells （HSCs） in both cell culture and animal models. Cytological experiments showed that MD-1 can inhibit the proliferation of HSC-T6 cells with a half-maximal inhibitory concentration （ICs0） of 62 pmollL. In addition, MD-1 more strongly inhibits the migration of HSC-T6 cells compared to MT and can more effectively induce G0/G1 arrest and apoptosis. Investigating the biological mechanisms underlying anti-hepatic fibrosis in the presence of MD-I, we found that MD-I can bind the epidermal growth factor receptor （EGFR） on the surface of HSC-T6 cells, which can further inhibit the phospho- rylaUon of EGFR and its downstream protein kinase B （Akt）, resulting in decreased expression of cyclin D1 and eventual inhibition of the activation of HSC-T6 cells. Furthermore, in rats with dimethylnitrosamine （DMN）- induced hepatic fibrosis, MD-1 slowed the development and progression of hepatic fibrosis, protecting hepatic parenchymal cells and improving hepatic functions. Therefore, MD-1 is a potential drug for anti-hepatic fibrosis.

关键词： matrine derivative hepatic stellate cellhepatic fibrosis epidermal growth factor receptor signaltransduction pathway