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Postpartum quality of life and mental health in women with heart disease:Integrated clinical communication and treatment

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World Journal of Psychiatry 2024年第1期14卷 63-75页

作者： Jia-Lin Liu Qi Wang dong-ying Qu Department of Obstetrics and Gynecology China Medical UniversityShenyang 110122Liaoning ProvinceChina Department of Psychiatry General Hospital of Northern Theater CommandShenyang 110016Liaoning ProvinceChina Department of Obstetrics and Gynecology General Hospital of Northern Theater CommandShenyang 110016Liaoning ProvinceChina

BACKGROUND Postpartum quality of life(QoL)in women with heart disease has been *** To improve clinical communication and treatment,we integrated medical data and subjective characteristics to study postpartum QoL *** The study assessed QoL 6 wk after birth using the 12-Item Short-Form Health *** Edinburgh Postnatal Depression Scale,Cardiac Anxiety Questionnaire,European Heart Failure Self-Care Behavior Scale,and a self-designed questionnaire based on earlier research were also used to assess patient *** data were *** models were created using multiple linear *** This retrospective study examined postpartum QoL in 105 cardiac *** QoL scores were lower(90.69±13.82)than those of women without heart disease,with physical component scores(41.09±9.91)lower than mental component scores(49.60±14.87).Postpartum depression(33.3%),moderate anxiety(37.14%),pregnancy concerns(57.14%),offspring heart problems(57.14%),and life expectancy worries(48.6%)were all *** previous cardiac surgery,multiparity,higher sadness and cardiac anxiety,and fear of unfavorable pregnancy outcomes were strongly related to lower QoL(R^(2)=0.525).CONCLUSION Postpartum QoL is linked to physical and mental health in women with heart *** study emphasizes the need for healthcare workers to recognize the unique characteristics of these women while developing and implementing comprehensive management approaches during their maternity care.

关键词： Heart disease Pregnancy Postpartum Quality of life Mental health

Polysaccharides from Chinese herbal medicine:a review on the hepatoprotective and molecular mechanism

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Chinese Journal of Natural Medicines 2024年第1期22卷 4-14页

作者： LI Jifeng GUO Haolin dong ying YUAN Shuo WEI Xiaotong ZHANG Yuxin dong Lu WANG Fei BAI Ting YANG Yong Dalian Key Laboratory of Chronic Disease Research Center Dalian UniversityDalian 116622China Key Laboratory of Natural Medicines of the Changbai Mountain Ministry of EducationCollege of PharmacyYanbian UniversityYanji 133002China

Polysaccharides,predominantly extracted from traditional Chinese medicinal herbs such as Lycium barbarum,Angelica sinensis,Astragalus membranaceus,Dendrobium officinale,Ganoderma lucidum,and Poria cocos,represent principal bioactive constituents extensively utilized in Chinese *** compounds have demonstrated significant anti-inflammatory capabilities,especially anti-liver injury activities,while exhibiting minimal adverse *** review summarized recent studies to elucidate the hepatoprotective efficacy and underlying molecular mechanisms of these herbal *** underscored the role of these polysaccharides in regulating hepatic function,enhancing immunological responses,and improving antioxidant capacities,thus contributing to the attenuation of hepatocyte apoptosis and liver *** of molecular pathways in these studies revealed the intricate and indispensable functions of traditional Chinese herbal polysaccharides in liver injury ***,this review provides a thorough examination of the hepatoprotective attributes and molecular mechanisms of these medicinal polysaccharides,thereby offering valuable insights for the advancement of polysaccharide-based therapeutic research and their potential clinical applications in liver disease treatment.

关键词： Polysaccharides Hepatoprotective Chinese herbal medicine Mechanism

Charge qubits based on ultra-thin topological insulator films

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Frontiers of physics 2024年第3期19卷 71-81页

作者： Kexin Zhang Hugo V.Lepage ying dong Crispin H.W.Barnes Research Center for Quantum Sensing Intelligent Perception Research InstituteZhejiang LabHangzhou 311121China Cavendish Laboratory Department of PhysicsUniversity of CambridgeCambridge CB30HEUnited Kingdom

We study how to use the surface states in a Bi2Se3 topological insulator ultra-thin film that are affected by finite size effects for the purpose of quantum *** demonstrate that:(i)surface states under the finite size effect can effectively form a two-level system where their energy levels lie in between the bulk energy gap and a logic qubit can be constructed,(ii)the qubit can be initialized and manipulated using electric pulses of simple forms,(iii)two-qubit entanglement is achieved through a√SWAP operation when the two qubits are in a parallel setup,and(iv)alternatively,a Floquet state can be exploited to construct a qubit and two Floquet qubits can be entangled through a Controlled-NOT *** Floquet qubit offers robustness to background noise since there is always an oscillating electric field applied,and the single qubit operations are controlled by amplitude modulation of the oscillating field,which is convenient experimentally.

关键词： topological insulator quantum computing nanodevices

Nano-scale Reinforcements and Properties of Al-Si-Cu Alloy Processed by High-Pressure Torsion

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Journal of Wuhan University of Technology(Materials Science) 2024年第5期39卷 1253-1259页

作者： dong ying WU Siyuan HE Ziyang LIANG Chen CHENG Feng HE Zuwei QIAN Chenhao School of Mechanical Engineering Jiangnan UniversityWuxi 214122China Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment and Technology Wuxi 214122China School of International Studies Renmin University of ChinaBeijing 100872China School of Engineering University of LiverpoolLiverpool L693GHUnited Kingdom

To improve the comprehensive mechanical properties of Al-Si-Cu alloy,it was treated by a high-pressure torsion process,and the effect of the deformation degree on the microstructure and properties of the Al-Si-Cu alloy was *** results show that the reinforcements(β-Si andθ-CuAl_(2)phases)of the Al-Si-Cu alloy are dispersed in theα-Al matrix phase with finer phase size after the *** processed samples exhibit grain sizes in the submicron or even nanometer range,which effectively improves the mechanical properties of the *** hardness and strength of the deformed alloy are both significantly raised to 268 HV and 390.04 MPa by 10 turns HPT process,and the fracture morphology shows that the material gradually transits from brittle to plastic before and after *** elements interdiffusion at the interface between the phases has also been effectively *** addition,it is found that the severe plastic deformation at room temperature induces a ternary eutectic reaction,resulting in the formation of ternary Al+Si+CuAl_(2)eutectic.

关键词： Al-Si-Cu alloy high-pressure torsion nano-scale reinforcements ternary eutectic

Mice with type I interferon signaling deficiency are prone to epilepsy upon HSV-1 infection

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Virologica Sinica 2024年第2期39卷 251-263页

作者： Wei Yang Chong-Yang Tang dong-ying Fan Yi-Song Wang Pei-Gang Wang Jing An Guo-Ming Luan Beijing Key Laboratory of Epilepsy Sanbo Brain HospitalCapital Medical UniversityBeijing100093China Beijing Institute for Brain Disorders Capital Medical UniversityBeijing100093China Department of Neurosurgery Epilepsy CenterSanbo Brain HospitalCapital Medical UniversityBeijing100093China Department of Microbiology School of Basic Medical SciencesCapital Medical UniversityBeijing100069China Chinese Institute for Brain Research Beijing102206China

Viral encephalitis continues to be a significant public health *** our previous study,we discovered a lower expression of antiviral factors,such as IFN-β,STING and IFI16,in the brain tissues of patients with Rasmussen's encephalitis(RE),a rare chronic neurological disorder often occurred in children,characterized by unihemispheric brain ***,a higher cumulative viral score of human herpes viruses(HHVs)was also found to have a significant positive correlation with the unihemispheric atrophy in *** I IFNs(IFN-I)signaling is essential for innate anti-infection response by binding to IFN-α/βreceptor(IFNAR).In this study,we infected WT mice and IFNAR-deficient A6 mice with herpes simplex virus 1(HSV-1)via periocular injection to investigate the relationship between IFN-I signaling and HHVs-induced brain *** all mice exhibited typical viral encephalitis lesions in their brains,HSV-induced epilepsy was only observed in A6 *** gene expression matrix,functional enrichment analysis and protein-protein interaction network revealed four gene models that were positively related with HSV-induced ***,ten key genes with the highest scores were *** together,these findings indicate that intact IFN-I signaling can effectively limit HHVs induced neural symptoms and brain lesions,thereby confirming the positive correlation between IFN-I signaling repression and brain atrophy in RE and other HHVs encephalitis.

关键词： IFN-I signaling Human herpes viruses(HHVs) Rasmussen's encephalitis(RE)

Durable ruthenium oxide catalysts for water oxidation reaction

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Science China Chemistry 2024年

作者： Jixiang Jiao Ding Chen Hongyu Zhao ying dong Shichun Mu State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology

Water electrolysis is an important way for high-purity hydrogen production. However, the oxygen evolution reaction（OER）, as a key reaction, has a high energy barrier, and the associated catalyst is prone to failure. Therefore, efficient and stable OER catalysts are urgently required. Compared with commercial iridium oxide（IrO2）, ruthenium oxide（RuO2） has a lower price and higher catalytic activity for OER due to its location at the near-top of the volcano plot, but has lower structural stability. Thus, an in-depth understanding of the failure mechanism of RuO2is conducive to the reaction pathway design and structural modulation for obtaining higher stable RuO2catalysts. Here, we discuss recent advances in the enhancement of the stability of RuO2catalysts. First, we analyze in depth the three failure modes of RuO2, including the oxidation of Ru, the lattice oxygen evolution,and the catalyst exfoliation during the OER process. Second, to improve the durability of RuO2catalysts, five modification strategies, comprising defective engineering, strain engineering, phase engineering, interface engineering and microenvironmental engineering, are summarized, and corresponding enhancement mechanisms are also discussed. Finally, the challenges and possible solutions for further breakthroughs of RuO2catalysts are proposed, and the future research trends and prospects of RuO2catalysts are also envisioned. Undoubtedly, this work will contribute to the understanding and design of highly stable OER catalysts and beyond.

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Efficient micrometer-scale thick-film perovskite solar cells with superior stability

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Rare Metals 2024年第4期43卷 1647-1657页

作者： Jian-Fei Hu Gang Chen Shun-Zhang Yu Yue-Xin Lin Kai-Yu Wang Zong-Wei Li Guo-dong Zhang Teng-Fei Pan Ya-Jing Li Ming-Jie Li ying-dong Xia Yi-Fan Lv Yong-Hua Chen Key Laboratory of Flexible Electronics(KLoFE)and Institute of Advanced Materials(IAM) School of Flexible Electronics(Future Technologies)Nanjing Tech University(NanjingTech)Nanjing211816China Department of Applied Physics The Hong Kong Polytechnic UniversityHong Kong999077China Shenzhen Research Institute The Hong Kong Polytechnic UniversityShenzhen518057China Optics Valley Laboratory Hubei430074China

It is essential to enhance the thickness of the absorber layer for perovskite solar cells(PSCs)to improve device performance and reduce industry ***,thick perovskite films(>1μm)are difficult to be fabricated by employing traditional solvents,such as N,N-dimethylformamide(DMF),dimethyl sulfoxide(DMSO).Besides,it is a challenge to fabricate thick-film perovskite owing to the deteriorated surface morphology and serious defect ***,a simple method was reported to deposit uniform pinhole-free perovskite films with a thickness of more than 2μm utilizing the methylamine acetate(MAAc)ionic liquid as the *** with methylammonium chloride(MACl)as an additive,thick-film perovskite with~2μm in grain size and few grain boundaries(GBs)was prepared,which dramatically improved the perovskite crystal quality and enhanced carrier transport *** final PSCs exhibited a power conversion efficiency(PCE)of 20.16%.The device showed improved stability with 95%of its initial efficiency in a nitrogen environment over 5000 *** work provides an alternative strategy to produce extremely efficient and stable thick-film *** can be believed that this device has great potential in the application of large areas and laminated PSCs.

关键词： Perovskite solar cells Thick-film Stability Ionic liquid

Narrowband blue emitter based on fused nitrogen/carbonyl combination with external quantum efficiency approaching 30%

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Science China Chemistry 2024年第1期67卷 351-359页

作者： Long Chen Jia-Heng Cai You-Jun Yu Yang-Kun Qu Sheng-Yi Yang Sheng-Nan Zou Rui-Hong Liu dong-ying Zhou Liang-Sheng Liao Zuo-Quan Jiang Institute of Functional Nano&Soft Materials(FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials&DevicesSoochow UniversitySuzhou 215123China Macao Institute of Materials Science and Engineering Macao University of Science and TechnologyMacao 999078China

Multi-resonance thermally activated delayed fluorescence(MR-TADF)emitters can enable narrowband emission with high color purity and electroluminescence ***/carbonyl(N/C=O)system is receiving increasing attention while the nitrogen/boron(N/B)system has been widely *** decoration is an effective approach for N/B type MR-TADF system but always leads to broadening and red-shifting of the emission band in N/C=O MR-TADF *** attribute these unfavorable phenomena to the formation of intramolecular charge transfer between the MR-core and peripheral *** address this issue,we have developed a new strategy by decorating DMQAO(a fused N/C=O MR-core)with a triazine acceptor and a neutral terphenyl group to construct MTDMQAO and MBDMQAO,*** introduction of the triazine acceptor not only realizes efficient narrowband emission in MTDMQAO,but also accelerates the reverse intersystem crossing process through enhanced spin-orbital *** a result,MTDMQAO exhibits a significantly higher external quantum efficiency of 29.4%compared to the referent emitters,validating the rationality of our derivation *** study highlights the potential of the N/C=O system for MR-TADF emitters and provides important insights for understanding the difference between N/B and N/C=O systems.

关键词： carbonyl group narrowband acceptor decoration thermally activated delayed fluorescence OLEDs

Chemical Constituents and Pharmacological Properties of Frankincense:Implications for Anticancer Therapy

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Chinese Journal of Integrative Medicine 2024年第8期30卷 759-767页

作者： WU Yong-rong XIONG Wei dong ying-jing CHEN Xin ZHONG Yuan-yuan HE Xin-ling WANG Yu-jia LIN Qun-fang TIAN Xue-fei ZHOU Qing College of Traditional Chinese Medicine Hunan University of Chinese MedicineChangsha410208China Department of Andrology the First Hospital of Hunan University of Chinese MedicineChangsha41007China College of Medicine Hunan University of Chinese MedicineChangsha410208China College of Traditional Chinese and Western Medicine Hunan University of Chinese MedicineChangsha410208China Hunan Provincial Key Laboratory of Traditional Chinese Medicine Prescription and Transformation Changsha410208China Hunan Sexual and Reproductive Health Clinical Medical Research Center of Traditional Chinese Medicine Changsha410021China

The discovery of novel antitumor agents derived from natural plants is a principal objective of anticancer drug ***,a widely recognized natural antitumor medicine,has undergone a systematic review encompassing its species,chemical constituents,and diverse pharmacological activities and *** different species of frankincense include Boswellia serrata,Somali frankincense,Boswellia frereana,and Boswellia *** frankincense extracts and compounds exhibit antitumor,anti-inflammatory,and hepatoprotective properties and antioxidation,memory enhancement,and immunological regulation *** also have comprehensive effects on regulating *** and its principal chemical constituents have demonstrated promising chemoprophylactic and therapeutic abilities against *** review provides a systematic summary of the mechanism of action underlying the antitumor effects of frankincense and its major constituents,thus laying the foundations for developing effective tumor-combating targets.

关键词： frankincense species chemical constituents anticancer therapy Chinesemedicine