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Nuclear Science and Techniques 2023年第12期34卷 229-241页

作者： Zhi‑Wei Zong Mao‑Song Cheng ying‑chi yu Zhi‑Min Dai Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China University of chinese Academy of Sciences Beijing 100049China

The complex structure and strong heterogeneity of advanced nuclear reactor systems pose challenges for high-fidelity neutron-shielding calculations. Unstructured meshes exhibit strong geometric adaptability and can overcome the deficiencies of conventionally structured meshes in complex geometry modeling. A multithreaded parallel upwind sweep algorithm for S_(N) transport was proposed to achieve a more accurate geometric description and improve the computational efficiency. The spatial variables were discretized using the standard discontinuous Galerkin finite-element method. The angular flux transmission between neighboring meshes was handled using an upwind scheme. In addition, a combination of a mesh transport sweep and angular iterations was realized using a multithreaded parallel technique. The algorithm was implemented in the 2D/3D S_(N) transport code ThorSNIPE, and numerical evaluations were conducted using three typical benchmark problems:IAEA, Kobayashi-3i, and VENUS-3. These numerical results indicate that the multithreaded parallel upwind sweep algorithm can achieve high computational efficiency. ThorSNIPE, with a multithreaded parallel upwind sweep algorithm, has good reliability, stability, and high efficiency, making it suitable for complex shielding calculations.

关键词： Shielding calculation Discrete ordinates method Discontinuous Galerkin finite element method Unstructured meshes

Mesenchymal-epithelial transition factor amplification correlates with adverse pathological features and poor clinical outcome in colorectal cancer

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World Journal of Gastrointestinal Surgery 2024年第5期16卷 1395-1406页

作者： Qiu-Xiao yu Ping-ying Fu chi Zhang Li Li Wen-Ting Huang Department of Pathology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital&Shenzhen HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeShenzhen 518116Guangdong ProvinceChina

BACKGROUND Colorectal cancer(CRC)is the third most common cancer and the second most common cause of cancer-related mortality ***-epithelial transition factor(MET)gene participates in multiple tumor biology and shows clinical potential for pharmacological manipulation in tumor *** amplification has been reported in CRC,but data are very *** pathological values of MET in CRC may provide new therapeutic and genetic screening options in future clinical *** To determine the pathological significance of MET amplification in CRC and to propose a feasible screening *** A number of 205 newly diagnosed CRC patients undergoing surgical resection without any preoperative therapy at Shenzhen Cancer Hospital of chinese Academy of Medical Sciences were *** patients were without RAS/RAF mutation or microsatellite *** amplification and c-MET protein expression were analyzed using fluorescence in situ hybridization(FISH)and immunohistochemistry(IHC),*** between MET aberration and pathological features were detected using the chi-squared *** free survival(PFS)during the two-year follow-up was detected using the Kaplan-Meier method and log rank *** results of MET FISH and IHC were com pared using one-way *** Polysomy-induced MET amplification was observed in 14.4%of cases,and focal MET amplification was not ***-induced MET amplification was associated with a higher frequency of lymph node metastasis(LNM)(P<0.001)and higher tumor budding grade(P=0.02).In the survival analysis,significant difference was detected between patients with amplified-and non-amplified MET in a two-year follow-up after the first diagnosis(P=0.001).C-MET scores of 0,1+,2+,and 3+were observed in 1.4%,24.9%,54.7%,and 19.0%of tumors,respectively.C-MET overexpression correlated with higher frequency of LNM(P=0.002),but no significant difference of PFS was dete

关键词： Colorectal cancer MET Amplification Pathological features Prognosis Fluorescence in situ hybridization

Association of plasma vitamin A level with type 2 diabetes mellitus:a community aging population-based cross-sectional study

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Food Science and Human Wellness 2024年第4期13卷 2079-2089页

作者： Pengfei Li Jingjing Xu yujie Guo Xiaojun Ma Shaobo Zhou chi Zhang Huiyan yu ying Wang Xixiang Wang Linhong yuan School of Public Health Beijing Key Laboratory of Environmental ToxicologyChina-British Joint Laboratory of Nutrition Prevention and Control of Chronic DiseasesCapital Medical UniversityBeijing 100069China School of Science Faculty of Engineering and ScienceUniversity of GreenwichChatham ME44TBUK School of Biological Sciences University of Nebraska-LincolnNE 68588-0660USA Suzhou Hospital Affiliated Hospital of Medical SchoolNanjing UniversitySuzhou 215153China

Recent studies indicated that vitamin A(VA)might be involved in the pathology of type 2 diabetes mellitus(T2DM).This cross-sectional study was conducted to explore the association between circulating VA level and T2DM.A total of 1818 subjects aged 50 years old and above were recruited from the *** logistic regression and restricted cubic spline(RCS)were applied to analyze the association of plasma VA level with the risk of *** VA and lipid-adjusted VA levels of T2DM patients were significantly higher than that of non-T2DM subjects(P<0.05).The ratios of plasma VA/total cholesterol(TC),VA/high-density lipoprotein cholesterol(HDL-c)and VA/low-density lipoprotein cholesterol(LDL-c)were positively associated with the risk of T2DM in the aging population(P<0.05).Compared with the Q1 level,subjects with Q2 to Q3 levels of plasma VA/triglyceride(TG)have decreased risk of T2DM(odds ratio(OR)Q2=0.68,P_(Q2)=0.021;ORQ3=0.59,P_(Q3)<0.01).Our results indicated that the imbalance of circulating lipids and VA might affect the relationship between VA and *** middle and aging subjects with higher ratios of plasma VA/TC,VA/HDL-c,and VA/LDL-c displayed increased risk for T2DM,but the moderate ratio of VA/TG might protect against risk of T2DM.

关键词： Type 2 diabetes mellitus Vitamin A Lipid Nutrition Disease prevention

Recent advances on bismuth oxyhalides for photocatalytic CO_(2)reduction

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Journal of Environmental Sciences 2024年第6期140卷 183-203页

作者： Liangpang Xu Jimmy C.yu ying Wang Department of Chemistry The Chinese University of Hong KongShatinNew TerritoriesHong Kong 999077China

Photocatalytic conversion of CO_(2)into fuels such as CO,CH_(4),and CH_(3)OH,is a promising approach for achieving carbon *** oxyhalides(BiOX,where X=Cl,Br,and I)are appropriate photocatalysts for this purpose due to the merits of visible-light-active,efficient charge separation,and easy-to-modify crystal structure and surface *** practical applications,multiple strategies have been proposed to develop high-efficiency BiOX-based *** review summarizes the development of different approaches to prepare BiOX-based photocatalysts for efficient CO_(2)*** the review,the fundamentals of photocatalytic CO_(2)reduction are ***,several widely used modification methods for BiOX photocatalysts are systematacially discussed,including heterojunction construction,introducing oxygen vacancies(OVs),Bi-enrichment,heteroatom-doping,and morphology ***,the challenges and prospects in the design of future BiOX-based photocatalysis for efficient CO_(2)reduction are examined.

关键词： Bismuth oxyhalides Photocatalysis CO_(2)reduction Modification methods

Surface modification by ligand growth strategy for dense copper bismuth film as photocathode to enhance hydrogen production activity

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Frontiers in Energy 2024年第1期18卷 89-100页

作者： Zhouzhou WANG Qingwei WU Jieming WANG ying yu Institute of Nanoscience and Nanotechnology College of Physical Science and TechnologyCentral China Normal UniversityWuhan 430079China

Hydrogen production from photoelectrochemical(PEC)water splitting has been regarded as a promising way to utilize renewable and endless solar ***,semiconductor film grown on photoelectrode suffers from numerous challenges,leading to the poor PEC ***,a straightforward sol-gel method with the ligand-induced growth strategy was employed to obtain dense and homogeneous copper bismuthate photocathodes for PEC hydrogen evolution *** various characterizations,it was found that the nucleation and surface growth of CuBi_(2)O_(4)layer induced by 2-methoxyethanol ligand(2-CuBi_(2)O_(4))demonstrated a decent crystallinity and coverage,as well as a large grain size and a low oxygen vacancy concentration,leading to the good ability of light absorption and carrier ***,under simulated sunlight irradiation(AM1.5G,100 mW/cm^(2)),the 2-CuBi_(2)O_(4)photocathode achieved an enhanced photocurrent density of−1.34 mA·cm^(−2)at 0.4 V versus the reversible hydrogen electrode and a promising applied bias photon-to-current efficiency of 0.586%.This surface modification by ligand growth strategy will shed light on the future design of advanced photoelectrodes for PEC water splitting.

关键词： copper bismuthate photocathode ligand growth strategy dense film PEC

Artificial Intelligence and Network Pharmacology Reveal the Medication Rules of Professor Wang yu-ying in the Treatment of Climacteric Syndrome

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World Journal of Traditional chinese Medicine 2024年第2期10卷 180-190页

作者： Meng-yuan Hu Tian-Xing Yi Qi-Rui Liu Xin-yu Zhang Ai-Ping Chen yu-ying Wang Yi Lu School of Traditional chinese Medicine Beijing University of Chinese MedicineBeijingChina

Objective: The objective of this study was to explore the medication rules and academic ideas of Professor Wang yu-ying in the treatment of climacteric syndrome(CLS) and to predict new prescriptions. Materials and Methods: The characteristics of frequency, clustering, four properties, and five flavors were analyzed, and new prescriptions were predicted through an artificial intelligence(AI)-based method. The potential pathways of new prescriptions were explored through network pharmacology-based analysis. Results: The top 16 medicinals used by Professor Wang yu-ying in the treatment of CLS included Danggui, Longgu, Muli, Fuling, Chuanxiong, Gancao, Xiangfu, and Tusizi. The AI method was applied to predict the basic prescription for treating CLS: Danggui 15 g, Duanlonggu 30 g, Duanmuli 30 g, Fuling 28 g, Chuanxiong 10 g, Gancao 6 g, Xiangfu 12 g, Tusizi 14 g, etc., Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses showed that the pathogenesis of CLS might be related to the estrogen pathway, involving typical steroid responses. Conclusions: This study summarized Professor Wang's medication experience in the treatment of CLS based on the data mining of clinical diagnoses and treatment cases. The AI method was used to predict the new prescription of CLS treatment, which was found to be reasonable by network pharmacology studies on its multi-target and multi-pathway mechanisms.

关键词： Artificial intelligence climacteric syndrome medication rules network pharmacology Professor Wang yu-ying

Multi-physical fields distribution in billet during helical electromagnetic stirring:A numerical simulation research

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china Foundry 2024年第1期21卷 51-59页

作者： Dong Pan Qing-tao Guo Kai-lun Zhang Fu-zhi yu yu-ying Li yu-bao Xiao State Key Laboratory of Metal Materials for Marine Equipment and Application Anshan 114009LiaoningChina Ansteel Beijing Research Institute Co. Ltd.Beijing 102200China

Electromagnetic stirring is one of the widely applied techniques to modify the quality of casting *** from conventional rotate stirring,the helical stirring is more professional in assisting multi-dimensional flow of molten metal and eliminating solidification *** this study,the single-winding helical stirring(SWHS)was introduced,offering advantages such as smaller volume and lower electromagnetic shielding compared to traditional helical stirring *** a comprehensive numerical simulation,the stirring parameters of SWHS were adjusted to yoke inclination angle of 43°and frequency of 12 *** higher electromagnetic force and flow velocity in drawing direction,as well as the lower temperature gradient induced by the SWHS,are positive factors for homogeneous solidification of *** experimental results on Al-8%Si alloy and 0.4%C-1.1%Mn steel demonstrate that compared to rotate stirring,the SWHS process can induce better billet quality and is more effective in accelerating the equiaxed expansion and reducing element *** SWHS process can enhance the equiaxed ratio of the billet by 58.3%and reduce segregation degree of carbon element by 10.97%.Consequently,SWHS holds great promise as a potential approach for improving the quality of continuous casting billets.

关键词： billet electromagnetic stirring helical solidification element segregation numerical simulation

Evolution of Biofilm and Its Effect on Microstructure of Mortar Surfaces in Simulated Seawater

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Journal of Wuhan University of Technology(Materials Science) 2024年第1期39卷 234-243页

作者：荣辉 yu Chenglong 张颖 School of Materials Science and Engineering Tianjin Chengjian UniversityTianjin 300384China Tianjin Key Laboratory of Building Green Functional Materials Tianjin Chengjian UniversityTianjin 300384China

To explore the role of biofilm formation on the corrosion of marine concrete structures, we investigated the attachment of biofilm on mortar surfaces in simulated seawater and the influence of biofilm on the microstructure of mortar surfaces. The results show that the evolution of biofilm on mortar surfaces in simulated seawater is closely related to the corrosion suffered by the mortar, and the process of biofilm attachment and shedding is continuous and cyclical. It is found that the specimens in the absence of biofilm attachment are more severely eroded internally by the corrosive medium in simulated seawater than those in the presence of biofilm attachment. For the specimens without biofilm attachment, after 60 days, gypsum forms,and after 120 days, the number of pores in the mortar is reduced. In contrast, for the specimens in the presence of biofilm attachment, gypsum could only be detected after 90 days, and fewer pores are filled. Therefore, the formation of biofilm could delay the invasion of the corrosive medium into the interior of mortar during the evolution of biofilm on mortar surfaces, mitigating the corrosion of mortars in seawater.

关键词： biofilm attachment mortar sulfur-oxidizing bacteria gypsum simulated seawater microstructure

SGT-Net: A Transformer-Based Stratified Graph Convolutional Network for 3D Point Cloud Semantic Segmentation

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Computers, Materials & Continua 2024年第6期79卷 4471-4489页

作者： Suyi Liu Jianning chi Chengdong Wu Fang Xu Xiaosheng yu Faculty of Robot Science and Engineering Northeastern UniversityShenyang110167China State Key Laboratory of Robotics Shenyang Institute of AutomationChinese Academy of SciencesShenyang110016China Institutes for Robotics and Intelligent Manufacturing Chinese Academy of SciencesShenyang110169China SIASUN Robot&Automation Co. Ltd.Shenyang110169China

In recent years,semantic segmentation on 3D point cloud data has attracted much *** 2D images where pixels distribute regularly in the image domain,3D point clouds in non-Euclidean space are irregular and inherently ***,it is very difficult to extract long-range contexts and effectively aggregate local features for semantic segmentation in 3D point cloud *** current methods either focus on local feature aggregation or long-range context dependency,but fail to directly establish a global-local feature extractor to complete the point cloud semantic segmentation *** this paper,we propose a Transformer-based stratified graph convolutional network(SGT-Net),which enlarges the effective receptive field and builds direct long-range ***,we first propose a novel dense-sparse sampling strategy that provides dense local vertices and sparse long-distance vertices for subsequent graph convolutional network(GCN).Secondly,we propose a multi-key self-attention mechanism based on the Transformer to further weight augmentation for crucial neighboring relationships and enlarge the effective receptive *** addition,to further improve the efficiency of the network,we propose a similarity measurement module to determine whether the neighborhood near the center point is *** demonstrate the validity and superiority of our method on the S3DIS and ShapeNet *** ablation experiments and segmentation visualization,we verify that the SGT model can improve the performance of the point cloud semantic segmentation.

关键词： 3D point cloud semantic segmentation long-range contexts global-local feature graph convolutional network dense-sparse sampling strategy

Classification of Sailboat Tell Tail Based on Deep Learning

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Journal of Ocean University of china 2024年第3期23卷 710-720页

作者： CHANG Xiaofeng yu Jintao GAO ying DING Hongchen LIU yulong yu Huaming Department of Physical Education Ocean University of ChinaQingdao 266100China College of Big Data Qingdao University of Science and TechnologyQingdao 266061China College of Oceanic and Atmospheric Sciences Ocean University of ChinaQingdao 266100China

The tell tail is usually placed on the triangular sail to display the running state of the air flow on the sail *** is of great significance to make accurate judgement on the drift of the tell tail of the sailboat during sailing for the best sailing *** it is difficult for sailors to keep an eye for a long time on the tell sail for accurate judging its changes,affected by strong sunlight and visual *** this case,we adopt computer vision technology in hope of helping the sailors judge the changes of the tell tail in ease with *** paper proposes for the first time a method to classify sailboat tell tails based on deep learning and an expert guidance system,supported by a sailboat tell tail classification data set on the expert guidance system of interpreting the tell tails states in different sea wind conditions,including the feature extraction *** the expression capabilities that vary with the computational features in different visual tasks,the paper focuses on five tell tail computing features,which are recoded by an automatic encoder and classified by a SVM *** experimental samples were randomly divided into five groups,and four groups were selected from each group as the training set to train the *** remaining one group was used as the test set for *** highest resolution value of the ResNet network was 80.26%.To achieve better operational results on the basis of deep computing features obtained through the ResNet network in the *** method can be used to assist the sailors in making better judgement about the tell tail changes during sailing.

关键词： tell tail sailboat classification deep learning