检索结果-南通市图书馆

Cyclosporin A protects Balb/c mice from liver damage induced by superantigen SEB and D-GaIN

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 1999年第3期5卷 209-212页

作者： yin, t tong, SQ Xie, YC Lu, DY Shanghai Second Med Univ Fac Med Lab Sci Ruijin Hosp Shanghai 200025 Peoples R China Shanghai Second Med Univ Dept Microbiol Shanghai 200025 Peoples R China Shanghai Second Med Univ Dept Internal Med Ruijin Hosp Shanghai 200025 Peoples R China

AIM to investigate the pathogenic effect ofSEB and D-GalN on liver and the protection ofcyclosporin A, the relationship between hepaticapoptosis and necrosis and the possiblemechanism of acute hepatic *** After staphylococcal enterotoxin B(SEB ) mixed with D--galactosamine (D-GaiN )were injected intraperitoneally into Balb/c miceand those previously treated with cyclosporin A,blood samples were collected and livers wereisolated at 2, 6, 12 and 24 h. Patterns othepatocellular death were studiedmorphologically and biochemically, circulatingcytokines (tNF-a, IFN--y ) and mice mortalitywithin 24h was ***’LtS the SEB could induce the typicalapoptotic changes of hepatocytes, the D-GaiNcould induce hepatocytes apoptosis anddegeneration at the same time, and the micehaving received the SEB + D-GaiN injectionsdeveloped apoptosis at 2 and 6 h, but after 12 hhepatocytes were characterized by severein jury, whereas all the examinations in thecyclosporin A treated mice were *** Hepatic cell apoptosis might berelated to necrosis, and massive hepatocyteapoptosis is likely the initiating step of acutehepatic necrosis in mice. the effects induced bySEB and D--GaiN on hepatocytes might bemediated by t cells, and could be prevented bycyclosporin A.

关键词： SEB CSA Cyclosporin A protects Balb/c mice from liver damage induced by superantigen SEB and D-GaIN

targeting EGFR and sonic hedgehog pathways for locally advanced eyelid and periocular carcinomas

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2014年第9期2卷 432-438页

作者： Vivian t yin Helen Merritt Bita Esmaeli Orbital Oncology and Ophthalmic Plastic Surgery Program Department of Plastic Surgery The University of Texas MD Anderson Cancer Center Department of Ophthalmology and Visual Science The University of Texas Medical School

For patients with metastatic or locally advanced eyelid and periocular carcinoma not amenable to surgical excision, targeted therapies have shown efficacy with better tolerability compared to cytotoxic chemotherapy. Overexpression of epithelial growth factor receptor was found in squamous cell carcinomas. Vismodegib targets the mutation in the hedgehog pathway identified in basal cell carcinoma and basal cell nevus syndrome. targeted therapies provide a novel and potentially effective treatment alternative for patients with eyelid carcinoma not amendable for surgery, including those with metastatic, locally advanced disease, advanced age, and significant comorbidities. High cost, need for long-term treatment, and toxicity are relative limitations.

关键词： Vismodegib Periocular basal cell carcinoma Sonic hedgehog Epithelial growth factor receptor inhibition Periocular squamous cell carcinoma

StRUCtURE IMPROVEMENt AND tEMPERAtURE FIELD SIMULAtION OF PREPARING NANOPOWDER BY EVAPORAtION-CONDENSAtION MEtHOD

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Metallurgica Sinica(English Letters) 2008年第3期21卷 178-182页

作者： J.S. Bao Y. yin t.G. Liu Z.Y. Yang School of Mechanical and Electrical Engineering China University of Mining and Technology Xuzhou221116 China

A new apparatus, with a segregable conical water cooling condenser, which is heated by an electric arc using the evaporation-condensation method to prepare carbon-coated nanopowder, has been developed by the authors. Numerical simulation of the temperature field is done by the ANSYS software, and temperature in the reaction vessel is measured with the help of an experiment, to verify the simulation result. Influence of the temperature field in the reaction vessel, on the process of preparing nanopowder is then discussed simply. It is shown that the segregable conical water cooling condenser and carbon-coated surface process can be used to prepare steady carbon-coated metal nanopowder, at a lower cost and higher yield rate than the traditional structure. Simulation of the temperature field in the apparatus shows that the arc heating method can form a temperature field in the apparatus, which is quite favorable for nanopowder formation. Experiments show that the rational parameters using this apparatus, with the arc heating method to prepare carbon-coated nanopowder are electricity 60-100 A and arc length 5-8 mm.

关键词： Evaporation-condensation method Electric arc heating temperature field Condenser structure

Lower Silurian Graptolites from tungtzu

在线全文

学校读者我要写书评

暂无评论

地质学报 1945年 211-219+338页

作者： t.H.yin and A.t.Mu (Geological Survey of China)

with 1 plate the graptolite faunas listed below were collected in 1944 by *** and the senior author from the so-called Chiutienya shale of Chiutienya,Hanchiatien,and *** and Hanchiatien lie within the

关键词： ACI Lower Silurian Graptolites from tungtzu

ACUtE MONOCYtIC LEUKEMIA CASE REPORt WItH AUtOPSY FINDINGS

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中华医学杂志(英文版) 1934年第11期48卷 1113-1125+1181页

作者： JULIA MORGAN yin-t'ANG HSU Departments of Medicine and Pathology Cheeloo University Hospital and School of MedicineTsinanShantungChina

*** is made of a case of acute monocytic leukemia in aChinese *** age of the patient,course of the disease,and the bloodfindings correspond,in the main,with those reported by others in *** in this case are the positive blood culture,thegross hematuria,the exceptionally high monocyte percentage in theperipheral blood with absence of polymorphonuclear neutrophiles,andulceration of the caecum found at *** autopsy showed an extremely generalized infiltration ofmonocytes throughout the organs.

关键词：

Sintering Formation of Low temperature Phase MnBi and Its Disordering in Mechanical Milling

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Materials Science & technology 1996年第5期12卷 335-341页

作者： yin, FX Gu, NJ Shigematsu, t Nakanishi, N KONAN UNIV FAC SCIDEPT CHEMKOBE 658JAPAN

With X-ray diffraction and DSC analysis, it is found that 4 cycles of sintering at 593 K are necessary for the complete production of the low-temperature phase (LtP) MnBi. the c/a of the fabricated LtP MnBi is 1.4286. Metastable phase MnBip formed in primary sintering stage of LtP MnBi has the similar crystal structure and lattice constant with the quenched high-temperature phase (HtP) Mn1.08Bi. the structural differences between MnBip phase and Mn1.08Bi phase are discussed. the LtP MnBi phase is unstable for strong mechanical milling as Bi appears after milling over 7200 s in the present milling condition. Strains caused by the mechanical attrition are difficult to accumulate in the MnBi crystals, and the crystal size of the milled MnBi is only 30 nm before the presence of grains coalescence. the whole milling process can be classified into 3 stages indicated by the structural changes. Based on the structural parameter calculation, the changes of atomic configurations in every stage have been discussed. the existence of Bi equivalent vacancy site is considered to play an important role in the disordering processes of Mn and Bi atoms.

关键词： Binary alloys

在线全文

学校读者我要写书评

暂无评论

条纹扫描干涉法测量齿轮齿面误差

计量学报 1988年第2期 120-123页

作者：郁道银近藤俊明大山永昭本田捷夫辻内顺平

本文根据条纹扫描干涉原理提出了齿轮齿面形状的非接触测量方法,并对实际齿面进行了测量实验,给出了齿面的误差分布。

关键词：齿面扫描干涉

Phase Diagram of a Spin-Orbit Coupled Dipolar Fermi Gas at t=0K

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics Letters 2020年第2期37卷 1-5页

作者： Xue-Jing Feng Lan yin School of Physics Peking UniversityBeijing 100871

We study a homogeneous two-component dipolar Fermi gas with 1D spin-orbit coupling(SOC)at zero temperature and find that the system undergoes a transition from the paramagnetic phase to the ferromagnetic phase under suitable dipolar interaction constantλd,SOC constantλSOC and contact interaction constant *** phase transition can be of either 1st order or 2nd order,depending on the *** the 2nd-order phase transition,the system is partially magnetized in the ferromagnetic *** SOC,the ferromagnetic phase can even exist in the absence of the contact *** increase in dipolar interaction,SOC strength,and contact interaction are all helpful to stabilize the ferromagnetic *** critical dipolar interaction strength at the phase transition can be reduced by the increase in SOC strength or contact *** diagrams of these systems are obtained.

关键词： interaction. state. ferromagnetic

Almost global smooth solutions of the 3D quasilinear Klein-Gordon equations on the product space R^(2)×t

在线全文

学校读者我要写书评

暂无评论

Science China Mathematics 2024年第12期67卷 2713-2752页

作者： Jun Li Fei tao Huicheng yin Department of Mathematics Nanjing UniversityNanjing 210093China School of Mathematical Sciences and Mathematical Institute Nanjing Normal UniversityNanjing 210023China

In this paper,for the 3D quadratic nonlinear Klein-Gordon equation on the product space R^(2)×t,we focus on the lower bound of the lifespan of the smooth solution with slowly decaying initial *** the size of initial data is bounded by ε_(0)>0,it is shown that a smooth solution exists up to the time C_(0)/20 with0 being sufficiently small and e^(c0)/ε_(0)^(2)>0 being some suitable *** that the solution of the corresponding 3D linear homogeneous Klein-Gordon equation on R^(2)×t only admits the optimal time-decay rate(1+t)−1,from which we generally derive the lifespan of the nonlinear Klein-Gordon equation up to e^(c0/ε0)rather than the more precise e^(c0/ε^(2)0) here.

关键词： quasilinear Klein-Gordon equation almost global solution Z-norm Littlewood-Paley decomposition space-time resonance method energy estimate