检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

公路边坡GFS生态防护基材力学与水稳特性

地球科学与环境学报 2024年第4期46卷 544-556页

作者：许飞王耿尹晓晴包含曹占强葛亚军敖新林郑涵北京首创环境科技有限公司北京100028 长安大学公路学院陕西西安710064 长安大学水利与环境学院陕西西安710054

裸露边坡在降雨和坡面径流作用下易发生冲蚀和垮塌,对坡面防护基材的力学和水稳特性提出了更高要求。在引入瓜尔豆胶、木纤维以及保水剂等功能材料的基础上,通过开展直剪试验、崩解试验、渗透试验、植生试验以及边坡模型冲刷试验,对比... 详细信息

裸露边坡在降雨和坡面径流作用下易发生冲蚀和垮塌,对坡面防护基材的力学和水稳特性提出了更高要求。在引入瓜尔豆胶、木纤维以及保水剂等功能材料的基础上,通过开展直剪试验、崩解试验、渗透试验、植生试验以及边坡模型冲刷试验,对比分析不同配比条件下瓜尔豆胶-纤维改性土新型生态防护基材(GFS)的力学强度和水稳能力,并采用响应面法与微观试验探究不同添加材料对基材性能的影响程度。结果表明:①功能材料均存在最优掺量使其对基材力学强度和水稳能力的强化效果达到最佳,最优掺量分别为瓜尔豆胶1.0%,木纤维1.5%,保水剂0.1%;②瓜尔豆胶和木纤维增强基材的抗剪强度,保水剂改善基材的水土保持能力,基材抗剪强度随瓜尔豆胶和木纤维掺量的增加先增大后减小;③功能材料的合理配置大幅度提升了基材的水稳能力,瓜尔豆胶配合适量的木纤维显著抑制了基材的崩解,保水剂增加了基材的有效含水量,降低了其饱和渗透系数;④功能材料对基材黏聚力、抗崩解能力以及渗透性能的影响程度表现为瓜尔豆胶最大,其次是木纤维,保水剂影响程度相对最小。

关键词：生态防护生态基材力学强度水稳性能响应面法生态功能电镜扫描核磁共振

A Novel Mutation of Filamin A Gene in a Chinese Family with Periventricular Nodular Heterotopia

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2016年第18期129卷 2262-2263页

作者： Wei-Dong Zhou Cheng-Hao Liu xiao-Min yin Qing-Yu Zeng Department of Neurology China Meitan General Hospital Beijing 100028 China Department of Neurology Graduate School North China University of Science and Technology Tangshan Hebei 063015 China Department of Radiology China Meitan General Hospital Beijing 100028 China

To the Editor： Periventricular nodular heterotopias （PNHs） represent a malformation of cortical development caused by an improper neuronal migration during forebrain formation, There is a wide spectrum of anatomical and clinical presentations of PNH, ranging from asymptomatic small unilateral or bilateral nodules to extensive agglomerates of heterotopia lining the lateral ventricles with epilepsy and intellectual disabilities. The mutations in X-linked gene, filamin A （FLNA） gene, were identified in approximately 100% of familial PNHs and 25% of sporadic cases Here, we reported a novel frameshift mutation of FLNA gene in a Chinese family with PNH.

关键词： Novel Mutation Filamin Gene

太子神悦胶囊治疗轻中度抑郁症的疗效和安全性

在线全文

学校读者我要写书评

暂无评论

中国新药杂志 2024年第8期33卷 792-797页

作者：徐保彦刘远新殷晓莉赵靖平伍海姗张克让肖卫东侯冬芬刘盈李成功李乐华中南大学湘雅二医院精神卫生研究所长沙410011 河北省精神卫生中心保定071000 新疆维吾尔自治区中医医院乌鲁木齐830000 辽宁中医药大学附属第二医院沈阳110034 山西医科大学第一医院太原030000 武汉大学人民医院武汉430060 天津中医药大学第二附属医院天津300150 中国医科大学附属第一医院沈阳110000 新疆华春生物药业股份有限公司乌鲁木齐830000

目的:评价太子神悦胶囊治疗轻中度抑郁症的疗效和安全性。方法:将研究对象随机分为试验组、阳性药组和安慰剂组,疗程为8周。以治疗终点的汉密尔顿抑郁17项(Hamilton Depression Scale-17 items,HAMD-17)量表减分值作为主要疗效评价指标... 详细信息

目的:评价太子神悦胶囊治疗轻中度抑郁症的疗效和安全性。方法:将研究对象随机分为试验组、阳性药组和安慰剂组,疗程为8周。以治疗终点的汉密尔顿抑郁17项(Hamilton Depression Scale-17 items,HAMD-17)量表减分值作为主要疗效评价指标,在基线、给药后1,2,4,8周末进行评价;安全性评价指标包括实验室检查、心电图检查、生命体征及不良事件发生率。结果:纳入符合标准的抑郁症患者601例。治疗终点3组间减分值比较差异有统计学意义(P0.05),尚不能认为试验组优于阳性药组。治疗期不良事件发生率分别为9.27%,15.97%,10.83%,组间差异无统计学意义(P>0.05)。结论:太子神悦胶囊治疗轻中度抑郁症安全有效。

关键词：轻中度抑郁症太子神悦胶囊中医药疗法安全性

腹膜恶性肿瘤从三焦癌毒辨治的理论依据与临床应用

在线全文

学校读者我要写书评

暂无评论

中医肿瘤学杂志 2024年第1期6卷 78-83页

作者：殷晓聆石齐杜美璐侯风刚上海中医药大学附属市中医医院上海200071

腹膜恶性肿瘤包括原发性腹膜癌和继发性腹膜恶性肿瘤,既往对其认识较少,随着外科肿瘤减灭术和腹腔热灌注化疗的兴起,腹膜恶性肿瘤的理念逐渐被接受,相关研究日益增多。结合历代古籍和临床经验,针对腹膜恶性肿瘤的特点,本文提出三焦为其... 详细信息

腹膜恶性肿瘤包括原发性腹膜癌和继发性腹膜恶性肿瘤,既往对其认识较少,随着外科肿瘤减灭术和腹腔热灌注化疗的兴起,腹膜恶性肿瘤的理念逐渐被接受,相关研究日益增多。结合历代古籍和临床经验,针对腹膜恶性肿瘤的特点,本文提出三焦为其病位,正虚癌毒为其病因,癌毒内结、三焦运化不畅为其病机;从三焦癌毒立法进行辨证论治,其治则为以攻毒为第一要素,以三焦为本,调达整体,并列举临床验案以资参考。

关键词：腹膜恶性肿瘤三焦癌毒辨证论治

Smart Gait:A Gait Optimization Framework for Hexapod Robots

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Mechanical Engineering 2024年第1期37卷 146-159页

作者： Yunpeng yin Feng Gao Qiao Sun Yue Zhao Yuguang xiao State Key Laboratory of Mechanical System and Vibration School of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240China Lenovo Corporation ShanghaiChina AI Institute School of Electronic Information and Electrical EngineeringShanghai Jiao Tong UniversityShanghai 200240China

The current gait planning for legged robots is mostly based on human presets,which cannot match the flexible characteristics of natural *** paper proposes a gait optimization framework for hexapod robots called Smart *** Gait contains three modules:swing leg trajectory optimization,gait period&duty optimization,and gait sequence *** full dynamics of a single leg,and the centroid dynamics of the overall robot are considered in the respective *** Smart Gait not only helps the robot to decrease the energy consumption when in locomotion,mostly,it enables the hexapod robot to determine its gait pattern transitions based on its current state,instead of repeating the formalistic clock-set step *** Smart Gait framework allows the hexapod robot to behave nimbly as a living animal when in 3D movements for the first *** Smart Gait framework combines offline and online optimizations without any fussy data-driven training procedures,and it can run efficiently on board in real-time after *** experiments are carried out on the hexapod robot *** results show that the energy consumption is reduced by 15.9%when in *** gait patterns can be generated spontaneously both in regular and challenge environments,and when facing external interferences.

关键词： Gait optimization Swing trajectory optimization Legged robot Hexapod robot

Association between availability of glucose-lowering drugs in primary health institutions and diabetes patients’medication adherence:a cross-sectional study in Shandong Province,China

在线全文

学校读者我要写书评

暂无评论

Global Health Journal 2021年第2期5卷 83-89页

作者： Jiansen Yao Haipeng Wang Di Shao Jia yin xiaolei Guo xiao yin Qiang Sun Center for Health Management and Policy Research School of Public HealthCheeloo College of MedicineShandong UniversityNo.44Wenhua West RoadLixia DistrictJinan 250012China Institute for Hospital Management Tsinghua UniversityUniversity Town of ShenzhenNanshan DistrictShenzhen 518055China Key Laboratory of Health Economics and Policy Research National Health Committee of the People’s Republic of ChinaNo.44Wenhua West RoadLixia DistrictJinan 250012China Shandong Center for Disease Control and Prevention No.16992Jingshi RoadLixia DistrictJinan 250014China Shandong University Affiliated Jinan Central Hospital No.105Jiefang RoadLixia DistrictJinan 250013China

Background:Primary health care system is a critical component of diabetes care and *** article aimed to analyze the availability of glucose-lowering drugs in primary health institutions(PHIs)in China,and to explore the relationship between availability of glucose-lowering drugs and medication adherence among type 2 diabetes mellitus(T2DM)***:This cross-sectional study conducted in Shandong Province,eastern China(hereafter referred to as Shandong),between August and December *** total,2520 community-managed T2DM patients were selected from 68 PHIs in Shandong,including 62 village-level and 6 township-level *** self-developed questionnaire was used to survey the availability of glucose-lowering drugs in ***’medication adherence was assessed by four self-reported questions,and was classified as either adherent or *** statistics was used to analyze the availability of glucose-lowering drugs in PHIs and the medication adherence among the T2DM *** logistic regression models were used to explore the relationship between the availability of glucose-lowering drugs in PHIs and patients’medication ***:A total of 1866 T2DM patients prescribed with at least one glucose-lowering drug were included in *** them,58.5%patients followed their antidiabetic treatment *** village-level PHIs,the patient’s adherence rate was lower than in township-level PHIs(55.9%vs.61.1%,P<0.05).Among the 68 PHIs,average(2.53±0.97)glucose-lowering products(generic names)were available,which in village-level PHIs were less than in township-level PHIs(2.47 vs.3.17,P<0.05).And the number of available glucose-lowering products in PHIs was associated with the adherence of T2DM ***:Poor availability of glucose-lowering products was found in PHIs in *** availability of glucose-lowering products in PHIs was positively associated with patients’medication adherence,and could be enha

关键词： Diabetes mellitus Primary health institutions Medication adherence Shandong China

Tripartition of Arbitrary Single-Qubit Information via a Class of Asymmetric Four-Qubit W State

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2009年第10期52卷 606-610页

作者： yin xiao-Feng LIU Yi-Min SHI Shi-Wei ZHANG Wen ZHANG Zhan-Jun School of Physics ＆ Material Science Anhui University Hefei 230039 China Department of Physics Shaoguan University Shaoguan 512005 China Key Laboratory of Optoelectronic Information Acquisition ＆ Manipulation of Ministry of Education School of Physics Material Science Anhui University Hefei 230039 China

A four-party scheme is put forward for a sender to partition arbitrary single-qubit information among three receivers by utilizing a class of asymmetric four-qubit W state as quantum channels. In the scheme the sender＇s quantum information can be recovered by the three receivers if and only if they collaborate together. Specifically, they collaborate to perform first two different 2-qubit collective unitary operations and then a single-qubit unitary operation. The scheme is symmetric and （3, 3）-threshold with regard to the reconstruction, for any receiver can be assigned to conclusively recover the quantum information with the other two＇s assistances.

关键词： four-party scheme tripartition arbitrary single-qubit quantum information asymmetric fourqubit W state

Signal transduction mediated by Bid, a pro-death Bcl-2 family proteins, connects the death receptor and mitochondria apoptosis pathways

在线全文

学校读者我要写书评

暂无评论

Cell Research 2000年第3期10卷 161-167页

作者： yin xiao-MING (Department of Pathology, University of Pittsburgh School of Medicine, 3550 Terrace Street, Pittsburgh, PA 15261, USA) DepartmentofPathology UniversityofPittsburghSchoolofMedicinePA15261USA.xmyin@pitt.edu

Two major apoptosis pathways have been defined in mammalian cells, the Fas/TNF-R1 death receptor pathway and the mitochondria pathway. The Bcl-2 family proteins consist of both anti-apoptosis and pro- apoptosis members that regulate apoptosis, mainly by controlling the release of cytochrome c and other mitochondrial apoptotic events. However, death signals mediated by Fas/TNF-R1 receptors can usually activate caspases directly, bypassing the need for mitochondria and escaping the regulation by Bcl-2 family proteins. Bid is a novel pro-apoptosis Bcl-2 family protein that is activated by caspase 8 in response to Fas/TNF-R1 death receptor signals. Activated Bid is translocated to mitochondria and induces cytochrome c release, which in turn activates downstream caspases. Such a connection between the two apoptosis pathways could be important for induction of apoptosis in certain types of cells and responsible for the pathogenesis of a number of human diseases.

关键词： Apoptosis Bcl-2 family proteins Bid Fas TNF.

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

不同枸杞扦插及水培生根能力比较分析

经济林研究 2024年第1期42卷 140-149页

作者：王嘉栋赵佳慧马西梅杨改儿段淋渊姚文孔尹晓李翔宁夏大学林业与草业学院宁夏银川750021 宁夏大学林木资源高效生产全国重点实验室宁夏银川750021 宁夏大学葡萄酒与园艺学院宁夏银川750021 宁夏农林科学院枸杞科学研究所宁夏银川750002

【目的】通过研究扦插及水培条件下不同品系或品种枸杞的生根能力,筛选出易于繁殖推广的枸杞材料,为枸杞的规模化繁育和高效培育提供科学参考。【方法】以14个不同枸杞品系或品种为材料,分别进行扦插和水培试验,测定扦插及水培后不同枸... 详细信息

【目的】通过研究扦插及水培条件下不同品系或品种枸杞的生根能力,筛选出易于繁殖推广的枸杞材料,为枸杞的规模化繁育和高效培育提供科学参考。【方法】以14个不同枸杞品系或品种为材料,分别进行扦插和水培试验,测定扦插及水培后不同枸杞的生根指标:平均根粗(mm),平均根长(mm),平均生根数,生根率(%)和生根效果指数,进行评价分析。【结果】对不同枸杞品系或品种扦插生根的所有指标进行相关性分析表明,平均生根数与平均根长之间的相关性达到显著水平(P<0.05),生根穗条数与平均根长、生根效果指数与平均生根数之间的相关性达到极显著水平(P<0.01)。主成分分析结果表明,3个主成分的累计贡献率达94.674%,表明3个主成分包含了大部分测定指标信息。根据主成分综合得分,扦插生根能力最好的前3个枸杞材料依次是C1(311.82)、C4(163.64)、C5(139.73)。对不同枸杞水培生根的所有指标进行相关性分析表明,平均根长数与平均根粗之间的相关性达到显著水平(P<0.05),生根效果指数与平均根长数之间的相关性达到极显著水平(P<0.01)。主成分分析结果表明,3个主成分的累计贡献率达到100%,说明3个主成分可以涵盖所有指标100%的信息。根据主成分综合得分,水培生根能力较强的前3个枸杞品系或品种依次是C1(252.143)、C4(218.376)、C3(175.501)。C1、C4这2个枸杞材料的扦插和水培生根能力均较强。【结论】不同品系或品种的枸杞生根能力具有显著差异,C1、C3、C4这3种叶用枸杞无论是在扦插还是水培的栽培方式下生根能力均较强,不同品系或品种的枸杞在扦插和水培的繁育方式下生根能力存在极显著差异,同时叶用枸杞的生根能力明显强于果用枸杞。

关键词：枸杞扦插水培生根率