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Cerium oxide nanoparticles-mediated cascade catalytic chemo-photo tumor combination therapy

Nano Research 2022年第1期15卷 333-345页

作者： Zitao Hu yin ding State Key Laboratory of Analytical Chemistry for Life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210093China

ROS-based tumor therapy based on nanocatalytic medicine has recently been proposed for its ***,a safe and highly efficient strategy towards getting high enough ROS to kill the hypoxic cancer cells is still a great ***,we report a simple pH/H_()20_(2)-activatable,O_(2)-evolving,and ROS regulating doxorubicin(DOX)and indocyanine green(ICG)co-loading PEGylated polyaniline(PANI)coated CeOx@polyacrylic acid(PAA)nanoclusters for highly selective and optimized cancer combination *** can selectively and greatly enhance intracellular O_(2) and ROS levels in tumor region,which depends on two-step catalytic properties of nanoceria(Ce^(4+)/Ce^(3+)=3.46,neutral surface charge,mostly localize into the cytoplasm,pH 7.4-6.5,catalase-like catalytic agents convert to Ce^(4+)/Ce^(3+)=0.58,negative surface charge,mostly localize into the lysosomes,pH 5-4,oxidase-like catalytic agents,triggered by near infrared(NIA)laser irradiation).Furthermore,the protective effect of polyethylene glycol(PEG),PANI,and PAA ensure that the nanoceria can only play the role of catalase under the irradiation of NIR light arrived at the tumor ***,loading of nanoceria and ICG onto PANI greatly enhanced photo thermal effect of nanoparticles.(NPs),which is useful for killing cancer cells by relieving hypoxia and promoting cross-membrane drug *** further enhance photodynamic therapy and chemotherapy *** chemo-photo combination therapies fantastically inhibited tumor growth and prevented tumor recurrence in vivo,suggesting a smart nanotheranostic system to achieve more precise and effective therapies in O_(2)-deprived tumor tissue.

关键词： nanocatalytic medicine photodynamic therapy hypoxia cerium oxide@polyaniline combination therapy

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Iterative subspace matching pursuit for joint sparse recovery

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The Journal of China Universities of Posts and Telecommunications 2023年第2期30卷 26-35页

作者： Shu Feng Zhang Linghua ding yin School of Communications and Information Engineering Nanjing University of Posts and TelecommunicationsNanjing 210003China

Joint sparse recovery(JSR)in compressed sensing(CS)is to simultaneously recover multiple jointly sparse vectors from their incomplete measurements that are conducted based on a common sensing *** this study,the focus is placed on the rank defective case where the number of measurements is limited or the signals are significantly correlated with each ***,an iterative atom refinement process is adopted to estimate part of the atoms of the support ***,the above atoms along with the measurements are used to estimate the remaining *** estimation criteria for atoms are based on the principle of minimum subspace *** numerical experiments were performed in noiseless and noisy scenarios,and results reveal that iterative subspace matching pursuit(ISMP)outperforms other existing algorithms for JSR.

关键词： joint sparse recovery(JSR) multiple measurement vector(MMV) support set estimation compressed sensing(CS)

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Seed Dynamics in Relation to Gaps in a Tropical Montane Rainforest of Hainan Island,South China:(Ⅰ)Seed Rain

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Journal of Integrative Plant Biology 2007年第11期49卷 1565-1572页

作者： Run-Guo Zang Wei-yin Zhang Yi ding Kay Laboratory of Forest Ecology and Environment the State Forestry Administration Institute of Forest Ecology Environment and Protection Chinese Academy of Forastry Beijing 100091 China

Seed dynamics is an important part of stand dynamics in forest ecosystems. In this paper, 26 gaps were randomly selected to study the influence of gaps on the spatial and temporal patterns of seed rains in a tropical montane rainforest of Hainan Island, South China. Three zones for each gap, including outside gap zone （Non-gap）, transitional gap zone （EG-CG）, and central gap zone （CG）, were designed, and fourseed traps （each lm x lm in size） were placed in each zone. Seed rains were collected by these traps every 10 days from June 2001 to May 2002. Seed rain varied greatly with season and generally exhibited a pattern of unimodal change during the study period： seed abundance and species richness were both greater in the wet season than in the dry season. Gaps significantly influenced the temporal patterns of both species richness and density of seed rains. Gaps had no significant influences on the spatial distribution patterns of seed rain species richness, but significantly affected the spatial distribution pattern of seed rain densities. Among the three different zones of gaps, the outside gap zone generally received more seeds inputs than the two other gap zones.

关键词： forest regeneration gap dynamics Hainan Island seed dispersal seed rain supply-side process tropical montane rain forest.

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Image interpretation: mining the visible and syntactic correlation of annotated words

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2009年第12期10卷 1759-1768页

作者： ding-yin XIA Fei WU Wen-hao LIU Han-wang ZHANG Scool of Computer Science and Technology Zhejiang University Hangzhou 310027 China

Automatic web image annotation is a practical and effective way for both web image retrieval and image understanding. However, current annotation techniques make no further investigation of the statement-level syntactic correlation among the annotated words, therefore making it very difficult to render natural language interpretation for images such as "pandas eat bamboo". In this paper, we propose an approach to interpret image semantics through mining the visible and textual information hidden in images. This approach mainly consists of two parts: first the annotated words of target images are ranked according to two factors, namely the visual correlation and the pairwise co-occurrence; then the statement-level syntactic correlation among annotated words is explored and natural language interpretation for the target image is obtained. Experiments conducted on real-world web images show the effectiveness of the proposed approach.

关键词： Web image annotation Visibility Pairwise co-occurrence Natural language interpretation

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Leaky Modes in Ag Nanowire over Substrate Configuration

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Chinese Physics Letters 2017年第9期34卷 58-61页

作者： yin-Xing ding Lu-Lu Wang Li Yu State Key Laboratory of Information Photonics and Optical Communications Beijing University of Posts and Telecommunications Belting 100876 School of Science Beijing University of Posts and Telecommunications Beijing 100876

By launching surface plasmons propagating along the Ag nanowire deposited on a substrate, we clearly observe three leaky modes using the Fourier imaging method. The effective refractive indexes, propagation lengths and electric field distributions of the modes are investigated, which indicate that the energy of the mode with a lowest effective refractive index is mainly distributed in the air, while for the other two modes, it is mainly distributed in the substrate and in the gap between the Ag nanowire and the substrate. These modes enable such a configuration to be used as a multichannel waveguide or highly directional optical antenna, which is of fundamental importance for optical device miniaturizations and photonic circuit integrations.

关键词： Surface plasmons

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Babinet-Inverted Optical Nanoantenna Analogue of Electromagnetically Induced Transparency

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Chinese Physics Letters 2018年第1期35卷 41-45页

作者： yin-Xing ding Lu-Lu Wang Li Yu State Key Laboratory of Information Photonics and Optical Communications Beijing University of Posts and TelecommunicationsBeijing 100876 School of Science Beijing University of Posts and TelecommunicationsBeijing 100876

A Babinet-inverted optical nanoantenna analogue of electromagnetically induced transparency based on the coupling between two magnetic dipole antennas and a magnetic octupole antenna in a Au film waveguide is *** results indicate that a pronounced elimination occurs in the radiating spectrum due to the coupling-induced radiation suppression.A two-oscillator electromagnetically induced transparency model is used to describe the *** coupling coefficient between the magnetic dipole antennas and the magnetic octupole antenna is calculated using the model and is found to decline exponentially with the increase of the distance between *** an antenna can be directly integrated with optical waveguides or transmission lines,thus is of fundamental significance for the applications in nano-optics,such as the optical device miniaturizations and photonic circuit integrations.

关键词： Light transmission

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Visualization analysis of research frontiers and trends in nerve regeneration and osseoperception in the repair of tooth loss

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Neural Regeneration Research 2014年第22期9卷 2013-2018页

作者： Xiaoge Zhang Tian Tang Zhihe Zhao Leilei Zheng yin ding State Key Laboratory of Military Stomatology Department of OrthodonticsSchool of Stomatologythe Fourth Military Medical University State Key Laboratory of Oral Diseases Department of OrthodonticsWest China Hospital of StomatologySichuan University Department of Orthodontics the Affiliated Hospital of StomatologyChongqing Medical University

This study analyzed 85 articles indexed by the Web of Science concerning nerve regeneration and osseoperception during tooth loss repair. Using the Web of Science database and Citespace Ⅲ software, a document co-citation network map was drawn by document co-citation analysis and word frequency analysis methods. Combined with emergent node secondary literature retrieval, subject headings with apparent changing word frequency trends were retrieved so as to identify research frontiers and development trends. Research frontiers and hotspots for neuronal calcium sensor protein were quantitatively explored to forecast future research developments in nerve regeneration and osseoperception during repair of tooth loss.

关键词： nerve regeneration tooth nerve injury peripheral nerve injury nerve repair osseoperception neuroprotection scientific map Web of Science Citespace neural regeneration

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Effect of carbon species on the reduction and melting behavior of boron-bearing iron concentrate/carbon composite pellets

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International Journal of Minerals,Metallurgy and Materials 2013年第6期20卷 522-528页

作者： Guang Wang yin-gui ding Jing-song Wang Xue-feng She Qing-guo Xue State Key Laboratory of Advanced Metallurgy University of Science and Technology Beijing

Iron nugget and boron-rich slag can be obtained in a short time through high-temperature reduction of boron- bearing iron concentrate by carbonaceous material, both of which are agglomerated together as a carbon composite pellet. This is a novel flow sheet for the comprehensive utilization of boron-bearing iron concentrate to produce a new kind of man-made boron ore. The effect of reducing agent species （i.e., carbon species） on the reduction and melting process of the composite pellet was investigated at a laboratory scale in the present work. The results show that, the reduction rate of the composite pellet increases from bituminite, anthracite, to coke at temperatures ranging from 950 to 1300~C. Reduction temperature has an important effect on the microstructure of reduced pellets. Carbon species also affects the behavior of reduced metallic iron particles. The anthracite-bearing composite pellet melts faster than the bituminite- bearing composite pellet, and the coke-bearing composite pellet cannot melt due to the high fusion point of coke ash. With anthracite as the reducing agent, the recovery rates of iron and boron are 96.5% and 95.7%, respectively. This work can help us get a further understanding of the new process mechanism.

关键词： iron ore pellets iron ore reduction boron bituminite anthracite coke

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Reduction Characteristics and Kinetics of Bayanobo Complex Iron Ore Carbon Bearing Pellets

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Journal of Iron and Steel Research International 2013年第5期20卷 28-33页

作者： ding yin-gui WANG Jing-song SHE Xue-feng WANG Guang XUE Qing-guo State Key Laboratory of Advanced Metallurgy University of Science and Technology Beijing

The kinetics of isothermal reduction of the carbon bearing pellets, which were mainly composed of Bayanobo complex iron ore and pulverized coal, was investigated by thermogravimetry at the temperature of 1 273-1 673 K. The effects of xC/xO and the atmospheres on the extent of reduction also were investigated. The results indicate that the fractional reaction increased proportionally with temperature increasing and heating temperature is the significant influence factor to the reaction of carbon bearing pellets. The optimum xC/xO is 1.2 and the effect of atmosphere on the reduction of iron oxides is almost negligible. The results can be interpreted that the reaction was initially controlled by a mixed controlled mechanism of carbon gasification and interface chemical reaction, and in the later stage, interface chemical reaction became the rate-controlling step. Apparent activation energy values of reduction at different levels of fractional reaction were calculated. Before F （fraction of reaction）=0.5, the apparent activation energy ranges from 66.39 to 75.64 kJ/mol, while after F=0.5, the apparent activation energy is 80.98 to 85.37 kJ/mol.

关键词： Bayanobo complex iron ore carbon bearing pellet thermogravimetry apparent activation energy

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Molecular phylogeny of Entomobrya (Collembola: Entomobryidae) from China: Color pattern groups and multiple origins

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Insect Science 2019年第3期26卷 587-597页

作者： yin-Huan ding Dao-Yuan Yu Wei-Bo Guo Jian-Nan Li Feng Zhang Department of Entomology College of Plant Protection Nanjing Agricultural University Nanjing China Department of Ecology College of Resources and Environmental Sciences Nanjing Agricultural University Nanjing China Institute of Environmental Sciences under Ministry of Environmental Protection Nanjing China

Highly diversified colorations among springtails (Collembola) have been widely used for species diagnosis, but their phylogenetic significance is poorly known. We addressed this issue in the largest Entomobryinae genus Entomobrya, which possesses variable color patterns among species. The relationships within the genus and to other genera have also rarely been studied. Based on material mainly from China, we have conducted a multilocus phylogeny and topology tests with likelihood and Bayesian algorithms, and accordingly demonstrated the non-monophyly of Chinese Entomobrya. The division of five clades, including Entomobrya and several related genera, coincided well with five types of colorations, respectively. Further analyses of divergence time and historical biogeography revealed that Chinese Entomobrya originated mainly from Palearctic (northern and western) China in the Paleocene and Eocene. This study highlights the great phylo? genetic values as well as taxonomic uses of coloration in Chinese Entomobrya. Multiple phylogenetic and biogeographic origins of Entomobrya imply its complicated relationships with both scaled and unsealed genera of Entomobryinae.

关键词： coloration Entomobrya Entomobryinae non-monophyly Palearctic origins

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