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呼吸机检测仪校准装置的研发

计量与测试技术 2024年第2期51卷 112-113,116页

作者：梅杰尹毓才解卓丽杨易航浙江省计量科学研究院(浙江省声学振动精密测量技术研究重点实验室)

近年来,呼吸机检测仪已逐渐随呼吸机的使用量不断增加而增加,由于我国目前对其校准的方式比较复杂,因此,为提供有效的量值溯源,需有效地研制出一台多参数集成的呼吸机检测仪校准装置。本文研制了一套呼吸机检测仪校准装置,保证了量值准... 详细信息

近年来,呼吸机检测仪已逐渐随呼吸机的使用量不断增加而增加,由于我国目前对其校准的方式比较复杂,因此,为提供有效的量值溯源,需有效地研制出一台多参数集成的呼吸机检测仪校准装置。本文研制了一套呼吸机检测仪校准装置,保证了量值准确可靠,可实现医院对其质量的有效监测与质量控制,从而保证治疗效果。

关键词：呼吸机检测仪校准规范多参数校准装置

Facile semisynthesis of histone H3 enables nucleosome probes for investigation of histone H_(3)K79 modifications

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Chinese Chemical Letters 2024年第10期35卷 321-324页

作者： Kun Zou yihang Xiao jinyu yang Mingxuan Wu Department of Chemistry Zhejiang UniversityHangzhou 310027China Department of Chemistry School of ScienceWestlake UniversityHangzhou 310030China Institute of Natural Sciences Westlake Institute for Advanced StudyHangzhou 310024China

Histone H3K79 modifications are essential to regulate chromatin structure and gene transcription,but understanding of the molecular mechanisms is *** H3K79 is at globular domain,short histone peptide cannot mimic H3K79 in ***,reconstituted nucleosome-based chemical tools are ideally used to investigate H3K79 *** consequence,H3K79-modified histone H3 with additional chemical handles are required,but such synthesis is challenging and *** we report a facile semisynthesis method that enables multifunctional histone H3 readily available.H3K79-containing fragment is short for straight peptide synthesis that was later ligated to recombinant expressed H3 fragments for full-length product in large *** a result,nucleosomes with H3K79 modifications as well as photo-reactive group and affinity tag were obtained to investigate potential binding *** believe this method that enhances synthetic accessibility of nucleosome probes will accelerate understanding of the underexplored H3K79 modifications.

关键词： Histone H3K79 modifications Methylation Succinylation Semisynthesis Nucleosome probes

High-performance Ta-doped Li_(7)La_(3)Zr_(2)O_(12) garnet oxides with AlN additive

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Journal of Advanced Ceramics 2022年第10期11卷 1530-1541页

作者： Chang ZHANG Xiangchen HU Zhiwei NIE Cong WU Nan ZHENG Shaojie CHEN yihang yang Ran WEI Jiameng YU Nan yang Yi YU Wei LIU School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210China Shanghai Key Laboratory of High-resolution Electron Microscopy ShanghaiTech UniversityShanghai 201210China

Garnet-type oxide is one of the most promising solid-state electrolytes(SSEs)for solid-state lithium-metal batteries(SSLMBs).However,the Li dendrite formation in garnet oxides obstructs the further development of the SSLMBs ***,we report a high-performance garnet oxide by using AlN as a sintering additive and Li as an anode interface *** with high thermal conductivity can promote the sintering activity of the garnet oxides,resulting in larger particle size and higher relative ***,Li3N with high ionic conductivity formed at grain boundaries and interface can also improve Li-ion transport *** a result,the garnet oxide electrolytes with AlN show enhanced thermal conductivity,improved ionic conductivity,reduced electronic conductivity,and increased critical current density(CCD),compared with the counterpart using Al_(2)O_(3) sintering *** addition,Li symmetric cells and Li|LiFePO_(4)(Li|LFP)half cells using the garnet electrolyte with the AlN additive exhibit good electrochemical *** work provides a simple and effective strategy for high-performance SSEs.

关键词： solid-state lithium-metal battery(SSLMB) garnet oxide thermal conductivity electronic conductivity critical current density(CCD)

轨道交通接触网停电作业接触式验电器仿真研究

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电力电容器与无功补偿 2024年第3期45卷 150-158页

作者：刘家杨一航符冠雄刘斌马明超中铁电气化局集团西安电气化工程有限公司西安710000 西安理工大学电气工程学院西安710054

在轨道交通中,接触式验电器用于接触网停电作业中检测接触网是否停电,以确保作业地线的正确操作和检修工作安全进行。接触电极作为接触式验电器的重要组成部分,直接影响验电信号的采集。为研究接触式验电器的接触电极结构对验电结果的影... 详细信息

在轨道交通中,接触式验电器用于接触网停电作业中检测接触网是否停电,以确保作业地线的正确操作和检修工作安全进行。接触电极作为接触式验电器的重要组成部分,直接影响验电信号的采集。为研究接触式验电器的接触电极结构对验电结果的影响,以GSY-II型27.5 k V交流验电器和ZGD型1 500 V直流验电器为例,分析了其工作原理,并仿真研究了接触电极形状和长度的改变对验电结果的影响。仿真结果表明:对于交流验电器,改变接触电极形状为圆钩型和V型,内部电路的感应信号电压分别变化了3.1%和2.3%,该变化对验电结果影响较小;增加接触电极长度会提高感应信号电压,从而提高验电灵敏度。对于直流验电器,其接触电极形状和长度改变后,内部电路的信号电压保持不变,因此接触电极的形状和长度不影响验电结果。仿真结果为设计和优化验电器结构提供了参考依据。

关键词：接触网停电作业接触式验电器接触电极信号电压

涎腺分泌性癌临床病理特征分析并文献复习(附4例)

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现代肿瘤医学 2024年第8期32卷 1435-1439页

作者：暴欣然徐晓艳马萍杨一航孟汀芳内蒙古医科大学基础医学院内蒙古呼和浩特010000 内蒙古医科大学基础医学院病理教研室内蒙古呼和浩特010000 内蒙古医科大学附属医院口腔科内蒙古呼和浩特010000

目的:研究并探讨涎腺分泌性癌(secretory carcinoma,SC)的临床病理特征、免疫表型、鉴别诊断、治疗及预后。方法:对4例涎腺分泌性癌进行HE染色和免疫组化染色,收集分析4例涎腺分泌性癌的临床资料并复习相关文献。结果:4例肿瘤均发生在腮... 详细信息

目的:研究并探讨涎腺分泌性癌(secretory carcinoma,SC)的临床病理特征、免疫表型、鉴别诊断、治疗及预后。方法:对4例涎腺分泌性癌进行HE染色和免疫组化染色,收集分析4例涎腺分泌性癌的临床资料并复习相关文献。结果:4例肿瘤均发生在腮腺,患者年龄为30岁~55岁,中位年龄为40岁;肿瘤直径为0.5 cm~3.0 cm;肿瘤组织均界限清楚,2例大部分切面灰白实性,质地中等;1例切面实性,灰粉灰黄相杂,质软易碎;1例呈囊实性改变,实性区质软灰粉色。镜下观察,肿瘤细胞排列成多种结构,可呈微囊、大囊及腺管内乳头状排列。肿瘤细胞界限不清,胞浆丰富,呈嗜酸性或空泡状,具有圆形或卵圆形的细胞核,核仁明显,核分裂象及坏死少见。4例肿瘤细胞CK5/6、p63均为阴性表达,肿瘤细胞均弥漫强表达S100、Mammaglobin,弥漫表达CKAE1/AE3、CK7、CK8、Vimentin,大部分肿瘤区域DOG1表达缺失,仅在少数瘤巢周或腔缘弱阳性,而Ki67增殖指数约10%。结论:发生于涎腺的分泌性癌类似于乳腺的分泌性癌,是一种少见的低度恶性肿瘤,由于其典型的形态学特征,并结合免疫组化结果即可做出诊断。ETV6-NTRK3基因检测可辅助诊断,治疗以手术切除为主辅以放化疗,预后较好。

关键词：涎腺分泌性癌病理学特征

Recent progress about transmission electron microscopy characterizations on lithium-ion batteries

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Journal of Energy Chemistry 2024年第8期95卷 39-56,I0002页

作者： yihang Liu Qiuyun Li Ziqiang Wang Institute of Materials Research Shenzhen International Graduate SchoolTsinghua UniversityShenzhen 518000GuangdongChina

With the rapid development of portable electronics,new energy vehicles,and smart grids,ion batteries are becoming one of the most widely used energy storage devices,while the safety concern of ion batteries has always been an urgent problem to be *** develop a safety-guaranteed battery,the characterization of the internal structure is indispensable,where electron microscopy plays a crucial *** on this,this paper summarizes the application of transmission electron microscopy(TEM)in battery safety,further concludes and analyzes the aspects of dendrite growth and solid electrolyte interface(SEI)formation that affect the safety of ion batteries,and emphasizes the importance of electron microscopy in battery safety research and the potential of these techniques to promote the future development of this *** advanced electron microscopy techniques and their prospects are also discussed.

关键词： Electron microscopy characterizations Lithium-ion batteries Dendrites SEI

Capacity Market Mechanism Design,Considering Network Optimization and Energy Transition

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CSEE Journal of Power and Energy Systems 2024年第4期10卷 1676-1687页

作者： Nan Shang yihang Song Xiang Zhang You Lin China Southern Power Grid Co. Ltd.Guangzhou 510663China Southern Methodist University Junkins 3086251 Airline Road DallasTX 75205US

The coordination of enrgy transition,fixed cost recovery,and sufficient generation supply leads to a new challenge for a traditional capacity market ***,in order to better match network expansion at the same time,it is crucial to redesign the capacity market mechanism considering system *** this paper,a novel capacity market mechanism is proposed considering spot market operations,network expansion,and energy transition,which can minimize the total cost of capacity investment,network expansion,and generation operations,while satisfying the energy transition constraints and topology ***,the capacity market mechanism co-ordinated with spot market operations is illustrated,in which the energy transition and network constraints are ***,a bi-level optimization model is established where the trade organizers minimize the total cost of both investment and operations,subject to the spot power market simultaneously minimizing the local dispatching *** numerical results of a test system show that more economical capacity portfolios can be obtained by constructing reasonable transmission lines,thereby obtaining a more optimal market cost.A detailed multi-scenario simulation is further analyzed to verify the effectiveness of the proposed market mechanism.

关键词： Capacity market energy transition network expansion spot market operation

基于改进的AlexNet模型的家用负载电弧检测

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传感技术学报 2023年第12期36卷 1928-1934页

作者：李斌杨亦航辽宁工程技术大学电气与控制工程学院辽宁葫芦岛125105

传统的电弧检测方法依赖人工设定阈值,存在误判的可能性,以及检测成功率不高等问题,提出了一种基于改进Alexnet深度学习卷积模型的电弧故障检测方法;该方法使用Adam算法代替SDG算法作为优化算法,加快模型的收敛速度,引入批量归一化算法... 详细信息

传统的电弧检测方法依赖人工设定阈值,存在误判的可能性,以及检测成功率不高等问题,提出了一种基于改进Alexnet深度学习卷积模型的电弧故障检测方法;该方法使用Adam算法代替SDG算法作为优化算法,加快模型的收敛速度,引入批量归一化算法,对数据进行归一化处理,改变卷积核的大小,减少网络参数数目。采用短时傅里叶变换(STFT)提取正常和故障时的电流信号时频信息,构建电流信号的时频图作为改进模型的输入,通过该改进的Alexnet模型实现电弧故障的检测。经过验证,该改进的模型电弧故障识别准确率能达到98%,并优于其他比较方法。

关键词：电弧故障检测时频图 Alexnet Adam 批量归一化

Bioactive Hydrogels with Pro-coagulation Effect for Hemostasis

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Chinese Journal of Chemistry 2024年第1期42卷 87-103,I0004页

作者： Quanshi Guo yihang Ding Lisha Yu Zongrui Tong Zhengwei Mao MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhouZhejiang 310058China Department of Hepatobiliary and Pancreatic Surgery The Second Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhouZhejiang 310009China Key Laboratory of Precision Diagnosis and Treatment for Hepatobiliary and Pancreatic Tumor of Zhejiang Province HangzhouZhejiang 310009China

Hemostatic hydrogels are widely applied for wound management of damaged tissues,traumatic wounds,and surgical *** hydrogels composed of bioactive components,including fibrin and thrombin,showed great promise in the clinic due to their good pro-coagulation *** the expanding knowledge of cascade reaction of blood coagulation and emerging bioactive substances,massive bioactive hydrogels consisting of peptides,hemocoagulase,polyphosphate(polyP),etc.,have been developed as effective hemostatic *** on the coagulation process and mechanism,we summarize the role of reported bioactive hydrogels in hemostasis in this *** conclude the key points in the coagulation process,including activation of coagulation factors,fibrinogen polymerization,etc.,then discuss how to design bioactive hydrogels to accelerate coagulation targeted to these ***,we conclude the progress and propose a perspective of bioactive hydrogels with a pro-coagulation effect for hemostasis.

关键词： Hemostasis Biological activity Biomaterials Enzyme catalysis Composites