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Journal of Iron and Steel Research International 2024年第8期31卷 2031-2040页

作者： Ting Dai De-yu Gu Yu-wen Qiu wei Guo Hui Ding yi-wei sun School of Materials Science and Engineering Jiangsu Key Laboratory of Advanced Metallic MaterialsSoutheast UniversityNanjing 211189JiangsuChina

The effect of spatial temperature gradient on the microstructural evolution of a 308L stainless steel during the directed energy deposition(DED)process was experimentally investigated.A novel cooling system was designed and incorporated to a DED system in order to control the temperature gradient along the deposition direction during *** deposition,the workpiece was placed on a lifting platform,and as the deposition process proceeded,the platform and workpiece were gradually lowered into cooling water so that the temperature gradient along the deposition direction could be controlled and maintained stable during the deposition *** microstructure characterization results indicated that a deposition strategy with higher G and G/R values(where G is temperature gradient and R is solidification rate)produced finer cellular grains that were better aligned with the deposition direction,while a deposition strategy with lower G and G/R values produced columnar grains with larger primary arm spacing and less aligned with the deposition direction.

关键词： Additive manufacturing Directed energy deposition Stainless steel Microstructure Temperature gradient

Performance of AC-LGAD strip sensors designed for the DarkSHINE experiment

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Nuclear Science and Techniques 2024年第11期35卷 152-163页

作者： Kang Liu Meng-Zhao Li Jun-Hua Zhang wei-yi sun Yun-Yun Fan Zhi-Jun Liang Yu-Feng Wang Mei Zhao Kun Liu Tsung‑Dao Lee Institute Shanghai Jiao Tong UniversityShanghai 201210China Key Laboratory for Particle Astrophysics and Cosmology(MOE) Shanghai Key Laboratory for Particle Physics and Cosmology(SKLPPC)Shanghai 200240China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China Institute of Nuclear and Particle Physics School of Physics and AstronomyShanghai Jiao Tong UniversityShanghai 200240China

The DarkSHINE experiment proposes a novel approach to single-electron-on-fixed-target exploration that focuses on the search for dark photons through their invisible decay into dark matter *** to this initiative is an advanced tracking detector designed to achieve exceptional sensitivity in the detection of light dark matter *** study evaluates the performance of several prototype AC-coupled low-gain avalanche diode(AC-LGAD)strip sensors specifically developed for the DarkSHINE tracking *** electrical properties of the sensors from two batches of wafers with different n^(+)doses are thoroughly *** and temporal resolutions are measured using an infrared laser *** spatial resolutions range from 6.5 to 8.2μm and from 8.8 to 12.3μm for the sensors from two distinct dose batches,each with a 100μm pitch ***,the sensors demonstrate time resolutions of 8.3 and 11.4 ps,underscoring the potential of AC-LGAD technology in enhancing the performance of the DarkSHINE tracking detector.

关键词： The DarkSHINE experiment Silicon-strip detector AC-LGAD sensor Spatial resolution Timing resolution

Laser ultrasonic testing for near-surface defects inspection of 316L stainless steel fabricated by laser powder bed fusion

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China Foundry 2021年第4期18卷 360-368页

作者： Ting Dai Xiao-jian Jia Jun Zhang Jin-feng Wu yi-wei sun Shu-xian Yuan Guan-bing Ma Xiao-jing Xiong Hui Ding School of Materials Science and Engineering Southeast UniversityNanjing 211189China School of Power and Mechanical Engineering Wuhan UniversityWuhan 430072China CGN Inspection Technology Co. Ltd.Suzhou 215100JiangsuChina Monash(Suzhou)Engineering Technology Co. Ltd.Suzhou 215123JiangsuChina

The laser powder bed fusion(L-PBF)method of additive manufacturing(AM)is increasingly used in various industrial manufacturing fields due to its high material utilization and design freedom of ***,the parts produced by L-PBF usually contain such defects as crack and porosity because of the technological characteristics of L-PBF,which affect the quality of the *** ultrasonic testing(LUT)is a potential technology for on-line testing of the L-PBF *** is a non-contact and non-destructive approach based on signals from abundant waveforms with a wide *** this study,a method of LUT for on-line inspection of L-PBF process was proposed,and a system of LUT was established approaching the actual environment of on-line detection to evaluate the method applicability for defects detection of L-PBF *** detection results of near-surface defects in L-PBF 316L stainless steel parts show that the crack-type defects with a sub-millimeter level within 0.5 mm depth can be identified,and accordingly,the positions and dimensions information can be *** results were verified by X-ray computed tomography,which indicates that the present method exhibits great potential for on-line inspection of AM processes.

关键词： additive manufacturing 316L stainless steel on-line inspection laser ultrasonic testing non-destructive testing

Mechanism of yinchenhao decoction in the treatment of jaundice based on network pharmacology

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Drug Combination Therapy 2020年第4期2卷 171-184页

作者： Nan Zhang Shu-ying Zhang wei-yi sun Department of General Surgery First Affiliated Hospital of Henan University of Chinese MedicineZhengzhouChina Hexing Town Health Center Suiping CountyZhumadian CityChina

Objective:This study aimed to examine the mechanism of classic ancient prescription of Chinese medicine yinchenhao decoction in treating jaundice based on network ***:An oral bioavailability of≥30%,a drug likeness of≥0.18,and literature studies were used to screen for yinchen(Artemisiae scopariae herba),Zhizi(Gardeniae fructus),Dahuang(Rhei radix et rhizome)in the Chinese Medicine System Pharmacology Database and Analysis *** active ingredient was introduced into the PubChem database to collect drug component targets and import into the Uniprot database for gene *** target gene of yinchen(Artemisiae scopariae herba)was screened via Human Gene Database(GeneCards).Then,use the Cytoscape 3.7.2 software was used for network visualization analysis,and the R3.6.1 software was used for gene ontology functional and Kyoto Encyclopedia of Genes and Genomes pathway enrichment ***:We collected a total of 47 active constituents of classic ancient prescription of Chinese medicine yinchenhao decoction,of which 17 were related to jaundice;189,9 targets of jaundice were screened,of which 41 were interdigitated with the targets of classic ancient prescription of Chinese medicine yinchenhao *** ontology functional enrichment analysis revealed 111 biological processes,14 cellular components,and 28 molecular functions,and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis showed 34 Kyoto Encyclopedia of Genes and Genomes pathways including hepatocellular carcinoma,PI3K-Akt signaling pathway,HIF-1 signaling pathway,prolactin signaling pathway,and non-alcoholic fatty liver ***:Based on the network pharmacology,the analysis of jaundice and classic ancient prescription of Chinese medicine yinchenhao decoction provides a novel idea and direction for the study of classic ancient prescription of Chinese medicine yinchenhao decoction in the treatment of jaundice.

关键词： Classic ancient prescription of Chinese medicine yinchenhao decoction Network pharmacology Jaundice Mechanism of action

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压力下铁砷基化合物的超导电性研究

物理学报 2017年第3期66卷 172-185页

作者：衣玮吴奇孙力玲中国科学院物理研究所北京100190 中国科学院大学北京100190

随着高压实验设备与技术的不断发展,压力作为对物质状态调控的独立变量在凝聚态物理研究中得到了越来越广泛的应用.高压研究对发现新材料、新现象、新规律及对其形成机理的理解和对相关理论的验证起到了不可替代的重要作用,近年来在对... 详细信息

随着高压实验设备与技术的不断发展,压力作为对物质状态调控的独立变量在凝聚态物理研究中得到了越来越广泛的应用.高压研究对发现新材料、新现象、新规律及对其形成机理的理解和对相关理论的验证起到了不可替代的重要作用,近年来在对铁基超导体超导电性的高压研究中取得的诸多重要研究进展充分说明了这一点.本文简要介绍了在压力下铁砷基超导体中呈现出的一些有趣的物理现象及其所反映出的物理内涵,例如,压力下对1111体系超导电性的研究在指导常压下用小离子半径元素替代获得最高超导转变温度的铁砷基超导体和推测铁砷基超导体超导转变温度上限等方面起到了重要作用;压力可抑制122体系母相的磁有序进而诱发超导电性,并揭示出Eu-122体系中Eu离子插层的磁有序与FeAs层超导电性的关系;在新型铁砷基超导体Ca_(0.73)La_(0.27)FeAs_2中发现的压致双临界点现象等.希望本文能对读者了解铁砷基超导体的高压研究进展情况有所帮助.

关键词：高压超导电性铁砷基超导体

Pregnancy Outcomes of In Vitro Fertilization with or without Ovarian Hyperstimulation Syndrome： A Retrospective Cohort Study in Chinese Patients

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Chinese Medical Journal 2015年第23期128卷 3167-3172页

作者： Xuan Jiang Cheng-Yan Deng Zheng-yi sun wei-Lin Chen Han-Bi Wang Yuan-Zheng Zhou Li Jin Department of Obstetrics and Gynecology Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College Beijing 100730 China

Background： The effect of ovarian hyperstimulation syndrome （OH SS） on pregnancy outcomes of in vitro fertilization （IVF） patients is still ambiguous. Tbis study aimed to analyze pregnancy outcomes of IVF with or without OHSS in Chinese patients. Methods： A retrospective cohort study was undertaken to compare pregnancy outcomes between 190 women with OHSS and 197 women without OHSS. We examined the rates of clinical pregnancy, multiple pregnancies, miscarriage, live birth, preterm deliver）,, preterm birth before 34 weeks＇ gestation, cesarean delivery, low birth weight （LBW）, and small-for-gestational age （SGA） between the two groups. Odds ratios （ORs） and 95% confidence intervals （Cls） of measure of clinical pregnancy were also analyzed. Results： The clinical pregnancy rate of OHSS patients was significantly higher than that of non-OHSS patients （91.8% vs. 43.5%, P 〈 0.001）. After controlling for drug protocol and causes of infertility, the adjusted ORs of moderate OHSS and severe/critical OHSS for clinical pregnancy were 4.65 （95% CI, 1.86-11.61 ） and 5.83 （95% CI, 3.45-9.86）, respectively. There were no significant differences in rates of muhiple pregnancy （4.0% vs. 3.7%） and miscarriage （16.1% vs. 17.5%） between the two groups. With regard to ongoing clinical pregnancy, we also found no significant differences in the rates of live birth （82.1% vs. 78.8%）, preterm delivery （20.9% vs. 17.5%）, preterm birth before 34 weeks＇ gestation （8.6% vs. 7.9%）, cesarean delivery （84.9% vs. 66.3%）, LBW （30.2% vs. 23.5%）, and SGA （21.9% vs. 17.6%） between the two groups. Conclusion： OHSS, which occurs in the luteal phase or early pregnancy in IVF patients and represents abnormal transient hemodynamics, does not exert any obviously adverse effect on the subsequent pregnancy.

关键词： In Vitro Fertilization Miscarriage Ovarian Hyperstimulation Syndrome Pregnancy Outcome Pregnancy Rate

甘草泻心汤联合美沙拉嗪对溃疡性结肠炎患者血清炎症因子和T淋巴细胞水平的影响

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世界华人消化杂志 2018年第32期26卷 1879-1885页

作者：孙译维张良上海市第七人民医院全科医学科上海市200137 上海市第一人民医院消化内科上海市200137

目的探讨甘草泻心汤联合美沙拉嗪治疗溃疡性结肠炎(ulcerativecolitis,UC)患者的临床效果观察及对血清炎症因子和T淋巴细胞水平的影响.方法选取2015-03/2017-03在上海市第七人民医院治疗的94例活动期UC患者,依据住院顺序随机分为观察组... 详细信息

目的探讨甘草泻心汤联合美沙拉嗪治疗溃疡性结肠炎(ulcerativecolitis,UC)患者的临床效果观察及对血清炎症因子和T淋巴细胞水平的影响.方法选取2015-03/2017-03在上海市第七人民医院治疗的94例活动期UC患者,依据住院顺序随机分为观察组和对照组,每组47例,对照组仅予以美沙拉嗪肠溶片口服治疗,观察组在对照组的基础上联合甘草泻心汤治疗,两组患者疗程均为6 wk,评估两组患者的临床治疗效果,观察比较治疗前后血清IL-6、IL-10、IL-17及TNF-α和外周血T淋巴细胞亚群CD4+、CD8+和CD4+/CD8+等水平的变化,并比较两组患者的生活质量情况.结果治疗6 wk后,观察组患者的临床总有效率及Mayo评分均显著高于对照组(P 0.05),但观察组患者外周血CD8+的水平较对照显著升高,CD4+/CD8+较对照组显著降低,差异具有统计学意义(P <0.05),治疗后观察组IBDQ各项评分与总评分显著高于对照组(P<0.05).结论甘草泻心汤联合美沙拉嗪治疗UC患者的临床效果较好,能够有效减轻机体炎症反应,并合理调节机体免疫功能,进而明显改善UC患者的临床症状,控制疾病活动,提高患者生活质量.

关键词：溃疡性结肠炎甘草泻心汤美沙拉嗪炎症因子 T淋巴细胞

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改性硅藻土脱除燃煤超细颗粒物的研究

工程热物理学报 2017年第8期38卷 1808-1813页

作者：张宇刘小伟徐义书孙伟徐明厚华中科技大学煤燃烧国家重点实验室武汉430074

本文分别采用盐酸和羟基铝溶液对硅藻土进行改性处理,将原硅藻土和两种改性硅藻土作为添加剂与煤粉按质量比3:100均匀混合后,在高温沉降炉1500℃下进行燃烧实验,利用低压撞击器(LPI)取样系统分级收集<10μm的颗粒物,研究超细颗粒物的生... 详细信息

本文分别采用盐酸和羟基铝溶液对硅藻土进行改性处理,将原硅藻土和两种改性硅藻土作为添加剂与煤粉按质量比3:100均匀混合后,在高温沉降炉1500℃下进行燃烧实验,利用低压撞击器(LPI)取样系统分级收集<10μm的颗粒物,研究超细颗粒物的生成特性;此外,将改性硅藻土与醋酸钠混合后在相同条件下燃烧,利用高温取样的方法(避免Na蒸汽物理冷凝),在950°℃下收集燃烧产物,消解后进行ICP-AES测试样品中Na的含量。实验结果表明:原硅藻土、酸改性和羟基铝改性硅藻土减排PM_(0.2)比例分别为:19.76%、28.77%和30.32%;在硅藻土及改性硅藻土与醋酸钠的反应实验中,与原硅藻土原土相比,酸改性和羟基铝改性硅藻土化学吸附Na的能力分别提高3.26%和22.18%;经分析后认为,盐酸改性主要使硅藻土比表面积增加、改善表面结构特性,提高了其物理吸附碱金属Na的能力;而羟基铝则会与硅藻土表面结合形成新的吸附表面,促进了硅藻土与.Na的化学反应,从而有效减少了PM_(0.2)的生成量。

关键词：燃煤 PM0.2 改性硅藻土吸附剂减排

Reducing sympathetic nervous tone in aged rats bettered cardiomyocyte contraction by improving the response of β_2-adrenoceptor

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中国病理生理杂志 2010年第A10期26卷 2044-2045页

作者： Wang ying1,Zhao Zhi2,Hao Yan-ling2,Xu Chuan-ying2,sun yi-wei2,sun Hong2(1Department of Pathophysiology,2Department of Physiology,XuZhou Medical College,Xuzhou221002,China)

The study was to investigate the effect of reducing central sympathetic nervous tone with clonidine on cardiomyocyte contraction,and further to analyze the influence of reducing the central sympathetic nervous tone on response of β1 and β2-AR in aged ventricular ***-Dawley rats were randomly divided into three groups:adult group,aged group and aged group with clonidine.

关键词： sympathetic adrenoceptor contraction cytes shortening antagonist pretreatment reduc evident clearly

Application of the improved dung beetle optimizer,muti-head attention and hybrid deep learning algorithms to groundwater depth prediction in the Ningxia area,China

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 18-23页

作者： Jiarui Cai Bo sun Huijun Wang yi Zheng Siyu Zhou Huixin Li Yanyan Huang Peishu Zong Collaborative Innovation Center on forecast and Evaluation of Meteorological Disasters/Key Laboratory of Meteorological Disaster Ministry of Education/Joint International Research Laboratory of Climate and Environment ChangeNanjing University of Information Science and TechnologyNanjingChina Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) ZhuhaiChina China Meteorological Administration Key Laboratory of Transportation MeteorologyNanjingChina Jiangsu Meteorological Observatory NanjingChina

Due to the lack of accurate data and complex parameterization,the prediction of groundwater depth is a chal-lenge for numerical *** learning can effectively solve this issue and has been proven useful in the prediction of groundwater depth in many *** this study,two new models are applied to the prediction of groundwater depth in the Ningxia area,*** two models combine the improved dung beetle optimizer(DBO)algorithm with two deep learning models:The Multi-head Attention-Convolution Neural Network-Long Short Term Memory networks(MH-CNN-LSTM)and the Multi-head Attention-Convolution Neural Network-Gated Recurrent Unit(MH-CNN-GRU).The models with DBO show better prediction performance,with larger R(correlation coefficient),RPD(residual prediction deviation),and lower RMSE(root-mean-square error).Com-pared with the models with the original DBO,the R and RPD of models with the improved DBO increase by over 1.5%,and the RMSE decreases by over 1.8%,indicating better prediction *** addition,compared with the multiple linear regression model,a traditional statistical model,deep learning models have better prediction performance.

关键词： Groundwater depth Multi-head attention Improved dung beetle optimizer CNN-LSTM CNN-GRU Ningxia