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Numerical investigation of the failure mechanism of cubic concrete specimens in SHPB tests

Defence Technology（防务技术） 2022年第1期18卷 1-11页

作者： Mei Li Hong hao Jian Cui yi-fei hao Labomtory of Coast Civil Structure Safety of Ministry of Education Tianjin UniversityTiarjin300072China chool of Civil Engineering.Tianin University Tianjin300072China entre for Infrastructural Monitoring and Protection School of Civil and Mechanical Engineering Curtin UniversityPerth Western Australia6845Australia

Cylindrical specimens are commonly used in Split Hopkinson pressure bar(SHPB)tests to study the uniaxial dynamic properties of concrete-like *** recent years,true tri-axial SHPB equipment has also been developed or is under development to investigate the material dynamic properties under tri-axial impact *** such tests,cubic specimens are *** is well understood that static material strength obtained from cylinder and cube specimens are *** factors are obtained and adopted in some guidelines to convert the material streng th obtained from the two types of *** uniaxial impact tests have also demonstrated that the failure mode and the strain rate effect of cubic specimens are very different from that of cylindrical ***,the mechanical background of these findings is *** an extension of the previous laboratory study,this study performs numerical SHPB tests of cubic and cylindrical concrete specimens subjected to uniaxial impact load with the validated numerical *** stress states of cubic specimens in relation to its failure mode under different strain rates is analyzed and compared with cylindrical *** detailed analyses of the numerical simulation results show that the lateral inertial confinement of the cylindrical specimen is higher than that of the cubic specimen under the same strain *** cubic specimen,the corners aremore severely damaged because of the lower lateral confinement and the occurrence of the tensile radial stress which is not observed in cylindrical *** results explain why the dynamic material strengths obtained from the two types of specimens are different and are strain rate *** on the simulation results,an empirical formula of conversion factor as a function of strain rate is proposed,which supplements the traditional conversion factor for quasi-static material *** can be used for transforming the dynamic compressive strength from

关键词： Concrete Lateral inertial confinement Shape effet Dynamic failure mechanism Strain rate

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Activation of adult endogenous neurogenesis by a hyaluronic acid collagen gel containing basic fibroblast growth factor promotes remodeling and functional recovery of the injured cerebral cortex

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Neural Regeneration Research 2025年第10期20卷 2923-2937页

作者： Yan Li Peng hao Hongmei Duan fei hao Wen Zhao Yudan Gao Zhaoyang Yang Kwok-Fai So Xiaoguang Li Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina China Rehabilitation Science Institute China Rehabilitation Research CenterBeijing Key Laboratory of Neural Injury and RehabilitationBeijingChina Center of Neural Injury and Repair Beijing Institute for Brain DisordersBeijingChina Beijing Key Laboratory for Biomaterials and Neural Regeneration School of Engineering MedicineBeihang UniversityBeijingChina Guangdong-HongKong-Macao Institute of CNS Regeneration Ministry of Education CNS Regeneration Collaborative Joint LaboratoryJinan UniversityGuangzhouGuangdong ProvinceChina Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory) GuangzhouGuangdong ProvinceChina Department of Ophthalmology and State Key Laboratory of Brain and Cognitive Sciences The University of Hong KongHong Kong Special Administration RegionChina Center for Brain Science and Brain-Inspired Intelligence Guangdong-HongKong-Macao Greater Bay AreaGuangzhouGuangdong ProvinceChina Co-innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Biomedical Engineering School of Biological Science and Medical EngineeringBeihang UniversityBeijingChina

The presence of endogenous neural stem/progenitor cells in the adult mammalian brain suggests that the central nervous system can be repaired and regenerated after ***,whether it is possible to stimulate neurogenesis and reconstruct cortical layers II to VI in non-neurogenic regions,such as the cortex,remains *** this study,we implanted a hyaluronic acid collagen gel loaded with basic fibroblast growth factor into the motor cortex immediately following traumatic *** findings reveal that this gel effectively stimulated the proliferation and migration of endogenous neural stem/progenitor cells,as well as their differentiation into mature and functionally integrated ***,these new neurons reconstructed the architecture of cortical layers II to VI,integrated into the existing neural circuitry,and ultimately led to improved brain *** findings offer novel insight into potential clinical treatments for traumatic cerebral cortex injuries.

关键词： adult endogenous neurogenesis basic fibroblast growth factor-hyaluronic acid collagen gel cortical remodeling functional recovery migration motor cortex injury neural circuits neural stem cells newborn neurons proliferation

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Crystallization Modulation and Holistic Passivation Enables Efficient Two‑Terminal Perovskite/CuIn(Ga)Se_(2)Tandem Solar Cells

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Nano-Micro Letters 2025年第1期17卷 205-215页

作者： Cong Geng Kuanxiang Zhang Changhua Wang Chung Hsien Wu Jiwen Jiang fei Long Liyuan Han Qifeng Han yi‑Bing Cheng Yong Peng State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070People’s Republic of China Triumph Photovoltaic Materials Co. Ltd.No.1001 Yannan AvenueHigh‑Tech Development DistrictBengbuAnhui 233000People’s Republic of China College of Materials Science and Engineering Guilin University of TechnologyGuilin 541004People’s Republic of China State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Two-terminal(2-T)perovskite(PVK)/CuIn(Ga)Se_(2)(CIGS)tandem solar cells(TSCs)have been considered as an ideal tandem cell because of their best bandgap matching regarding to Shockley–Queisser(S–Q)***,the nature of the irregular rough morphology of commercial CIGS prevents people from improving tandem device *** this paper,D-homoserine lactone hydrochloride is proven to improve coverage of PVK materials on irregular rough CIGS surfaces and also passivate bulk defects by modulating the growth of PVK *** addition,the minority carriers near the PVK/C60 interface and the incompletely passivated trap states caused interface recombination.A surface reconstruction with 2-thiopheneethylammonium iodide and N,N-dimethylformamide assisted passivates the defect sites located at the surface and grain ***,LiF is used to create this field effect,repelling hole carriers away from the PVK and C60 interface and thus reducing *** a result,a 2-T PVK/CIGS tandem yielded a power conversion efficiency of 24.6%(0.16 cm^(2)),one of the highest results for 2-T PVK/CIGS TSCs to our *** validation underscores the potential of our methodology in achieving superior performance in PVK/CIGS tandem solar cells.

关键词： PVK/CIGS TSCs Irregular rough surfaces Modulating the growth PVK/C60 interface recombination

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木浆源甾醇对高脂高胆固醇仓鼠胆固醇代谢基因表达的影响

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营养学报 2018年第1期40卷 53-58页

作者：杨胜楠李祥王慧孙振欧王轶菲王浩天津科技大学食品营养与安全重点实验室天津300457 盐城师范学院海洋与生物工程学院盐城224051

目的研究木浆源甾醇对高脂高胆固醇仓鼠肝脏中胆固醇代谢基因表达的影响。方法测定空白组、高脂组、实验组仓鼠的质量、脏器重量、血清中总胆固醇(total cholesterol,TC)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL... 详细信息

目的研究木浆源甾醇对高脂高胆固醇仓鼠肝脏中胆固醇代谢基因表达的影响。方法测定空白组、高脂组、实验组仓鼠的质量、脏器重量、血清中总胆固醇(total cholesterol,TC)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)、甘油三酯(triglyceride,TG)水平。检测肝脏中胆固醇代谢相关调控基因m RNA表达水平及肝脏胆固醇含量和粪便固醇排泄量。结果木浆源甾醇可以极显著降低TC、TG、和Non HDL-C水平(P<0.01),同时极显著降低肝脏中胆固醇含量和肝脏重量(P<0.01),显著增加粪中固醇排泄量(P<0.05)。实验组肝脏中SREBP2、CYP7A1、HMG-Co A-R和LDL-R m RNA表达水平显著上调(P<0.05)。给予木浆源甾醇后可以改变肠道菌群多样性,增加有益菌减少有害菌数量。结论木浆源甾醇可能通过调控肝脏中胆固醇代谢相关基因的表达,抑制胆固醇的合成吸收并增加固醇的排泄,同时丰富肠道微生物多样性,增加有益菌数量,协同作用调控机体胆固醇的代谢。

关键词：木浆源甾醇胆固醇基因表达肠道菌群

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High-dose dexamethasone regulates microglial polarization via the GR/JAK1/STAT3 signaling pathway after traumatic brain injury

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Neural Regeneration Research 2025年第9期20卷 2611-2623页

作者： Mengshi Yang Miao Bai Yuan Zhuang Shenghua Lu Qianqian Ge hao Li Yu Deng Hongbin Wu Xiaojian Xu fei Niu Xinlong Dong Bin Zhang Baiyun Liu Beijing Tiantan Hospital Capital Medical UniversityBeijingChina Department of Neurology The First Hospital of Tsinghua UniversityBeijingChina Department of Neurotrauma and Beijing Key Laboratory of Central Nervous System Injury Beijing Neurosurgical InstituteCapital Medical UniversityBeijingChina Department of Critical Care Medicine Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Center for Nerve Injury and Repair Beijing Institute of Brain DisordersChina National Clinical Research Center for Neurological DiseasesBeijingChina

Although microglial polarization and neuroinflammation are crucial cellular responses after traumatic brain injury,the fundamental regulatory and functional mechanisms remain insufficiently *** potent anti-inflammato ry agents,the use of glucoco rticoids in traumatic brain injury is still controversial,and their regulatory effects on microglial polarization are not yet *** the present study,we sought to determine whether exacerbation of traumatic brain injury caused by high-dose dexamethasone is related to its regulatory effects on microglial polarization and its mechanisms of *** vitro cultured BV2 cells and primary microglia and a controlled cortical impact mouse model were used to investigate the effects of dexamethasone on microglial ***,dexamethasone,RU486(a glucocorticoid receptor antagonist),and ruxolitinib(a Janus kinase 1 antagonist)were ***-sequencing data obtained from a C57BL/6 mouse model of traumatic brain injury were used to identify potential targets of *** Morris water maze,quantitative reverse transcription-polymerase chain reaction,western blotting,immunofluorescence and confocal microscopy analysis,and TUNEL,Nissl,and Golgi staining were performed to investigate our ***-throughput sequencing results showed that arginase 1,a marker of M2 microglia,was significantly downregulated in the dexamethasone group compared with the traumatic brain injury group at3 days post-traumatic brain *** dexamethasone inhibited M1 and M2 microglia,with a more pronounced inhibitory effect on M2microglia in vitro and in *** receptor plays an indispensable role in microglial polarization after dexamethasone treatment following traumatic brain ***,glucocorticoid receptor activation increased the number of apoptotic cells and neuronal death,and also decreased the density of dendritic spines.A possible downstream receptor signaling mechanism is th

关键词： apoptosis BV2 microglia dexamethasone glucocorticoid receptor glucocorticoids innate immune system microglial polarization neuroinflammation primary microglia traumatic brain injury

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Low-Temperature Fabrication of Stable Black-Phase CsPbI₃ Perovskite Flexible Photodetectors Toward Wearable Health Monitoring

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NANO-MICRO LETTERS 2025年第1期17卷 1-14页

作者： Zhao, yingjie Sun, yicheng Pei, Chaoxin yin, Xing Li, Xinyi hao, yi Zhang, Mengru Yuan, Meng Zhou, Jinglin Chen, Yu Song, Yanlin Zhengzhou Univ Coll Chem Zhengzhou 450001 Peoples R China Zhengzhou Univ Pingyuan Lab Zhengzhou 450001 Peoples R China Chinese Acad Sci Inst Chem Key Lab Green Printing Beijing 100190 Peoples R China Chinese Acad Sci Tech Inst Phys & Chem Key Lab Bioinspired Mat & Interfacial Sci Beijing 100190 Peoples R China Chinese Acad Sci Inst High Energy Phys Beijing 100049 Peoples R China

Low-temperature fabrication of black-phase CsPbI3 perovskite films is first demonstrated by using diphenylphosphinic chloride additive under 30-50 degrees C, arising from the steric effect and chloride insertion ***-area high-quality all-inorganic perovskite films with fewer defects enhanced crystallographic orientation, and excellent environmental stability is *** record performances are demonstrated for flexible wearable photodetectors with a responsivity of 42.1 A W-1, a detectivity of 1.3 x 1014 Jones, high-fidelity image, photoplethysmography sensor functions, and high mechanical stability. Flexible wearable optoelectronic devices fabricated from organic-inorganic hybrid perovskites significantly accelerate the development of portable energy, biomedicine, and sensing fields, but their poor thermal stability hinders further applications. Conversely, all-inorganic perovskites possess excellent thermal stability, but black-phase all-inorganic perovskite film usually requires high-temperature annealing steps, which increases energy consumption and is not conducive to the fabrication of flexible wearable devices. In this work, an unprecedented low-temperature fabrication of stable black-phase CsPbI3 perovskite films is demonstrated by the in situ hydrolysis reaction of diphenylphosphinic chloride additive. The released diphenyl phosphate and chloride ions during the hydrolysis reaction significantly lower the phase transition temperature and effectively passivate the defects in the perovskite films, yielding high-performance photodetectors with a responsivity of 42.1 A W-1 and a detectivity of 1.3 x 1014 Jones. Furthermore, high-fidelity image and photoplethysmography sensors are demonstrated based on the fabricated flexible wearable photodetectors. This work provides a new perspective for the low-temperature fabrication of large-area all-inorganic perovskite flexible optoelectronic devices.

关键词： In situ hydrolyzation Low-temperature processing All-inorganic perovskite Flexible photodetectors Health monitoring

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CD64检测在新生儿呼吸道细菌感染早期诊断中的价值

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中国卫生检验杂志 2017年第1期27卷 80-81,84页

作者：胡益飞徐浩吴淋淋金华市中心医院检验科浙江金华321000 金华市人民医院妇产科浙江金华321000

目的探讨应用流式细胞术检测中性粒细胞CD64指数,研究其在新生儿呼吸道细菌感染中的早期诊断作用。方法选自2014年6月-2016年4月本院新生儿科收治住院的71例呼吸道感染患儿,平均日龄为6.8 d,其中细菌感染组(30例)、病毒感染组(26例)、... 详细信息

目的探讨应用流式细胞术检测中性粒细胞CD64指数,研究其在新生儿呼吸道细菌感染中的早期诊断作用。方法选自2014年6月-2016年4月本院新生儿科收治住院的71例呼吸道感染患儿,平均日龄为6.8 d,其中细菌感染组(30例)、病毒感染组(26例)、支原体感染(15例),另选取20例健康体检者作为健康对照组。采用流式细胞术(FCM)检测外周血中CD64指数。CRP测定采用超敏免疫比浊法,白细胞计数采用血常规仪器。结果新生儿细菌感染组CD64指数、WBC和CRP明显高于病毒感染组、支原体感染组和健康对照组,差异均有统计学意义(P<0.01)。ROC曲线计算得出,CD64指数在截断值1.786时,诊断新生儿呼吸道细菌感染的灵敏度为91.4%,特异度为92.5%,优于CRP和WBC。结论 CD64指数具有高灵敏度及特异度的优点,对新生儿呼吸道细菌感染早期诊断具有重要意义。

关键词：流式细胞术 CD64指数新生儿细菌感染 C-反应蛋白

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Clinicopathological differences between patients with schistosomal appendicitis and non schistosomal appendicitis:A retrospectively study of past ten years

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World Journal of Clinical Cases 2025年第2期13卷 24-32页

作者： Xiao-yi Wang Yao hao Zi-Jian Wang Xiu-Liang Xu Jiang-Hua Yang Department of Infectious Diseases The First Affiliated of Wannan Medical CollegeWuhu 241001Anhui ProvinceChina

BACKGROUND Chronic schistosomiasis causes multiple organ and multiple system diseases,especially the digestive *** eggs are mainly deposited in the stomach,liver and colorectal,but a few eggs are deposited in the appendix and cause *** present,there are few studies on schistosomal *** To explore the differences in epidemiological,clinical and pathological characteristics between schistosomal appendicitis and non-schistosomal appendicitis over the past decade in order to assess the impact of schistosomiasis on *** The differences of general data,clinical data and laboratory examination data of patients with appendicitis from October 2013 to October 2023 were retrospectively *** patients were divided into two groups for *** were 136 patients in schistosomal appendicitis group and 5418 patients in non-schistosomal appendicitis *** Schistosomal appendicitis accounted for 2.45%of all patients with appendicitis,and the annual proportion in the past decade was 2.2%,2.9%,1.8%,1.9%,3.4%,3.1%,1.9%,1.6%,3%,2.6%,*** prevalence of schistosomal appendicitis was middle-aged and elderly males,with an average age of 61.73±15.335 *** main population of non-schistosomal appendicitis was middle-aged men,with an average age of 35.8±24.013 years(P<0.001).The distribution of pathological types of appendicitis was different between the two groups(P<0.001).The incidence of acute suppurative appendicitis in non-schistosomal appendicitis was higher than that in schistosomal appendicitis[odds ratio(OR)=0.504;95%confidence interval(CI):0.349-0.728;P<0.001].The proportion of acute attack of chronic appendicitis in schistosomal appendicitis was higher than that in non-schistosomal appendicitis(OR=2.614;95%CI:1.815-3.763;P<0.001).The proportion of schistosomal appendicitis patients complicated with colorectal cancer was higher than that of nonschistosomal appendicitis patients(OR=5.087;95%CI:1.427-

关键词： Schistosomal appendicitis Schistosomiasis Appendix Colorectal cancer Clinicopathological characteristics

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Small modifications of endo-functionalized cavities lead to large changes in molecular interaction in water

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Science China Chemistry 2025年第1期 369-376页

作者： Song-Meng Wang hao Nian Yan-Fang Wang Li-Shuo Zheng Yu-Tao Zheng yi-Wei Dong Liping Huang Xiaoping Wang Wei Jiang Liu-Pan Yang Department of Chemistry Southern University of Science and Technology School of Chemistry and Pharmaceutical Sciences State Key Laboratory for Chemistry and Molecular Engineering of Medicinal ResourcesGuangxi Normal University School of Pharmaceutical Science Hengyang Medical School University of South China

Studying molecular recognition in aqueous environments is crucial for understanding biological processes. Herein, we present a series of N-doped endo-functionalized anthracene-based cavities by introducing inward-directed pyridine units. The subtle modifications can significantly affect the binding properties of these receptors, which is similar to the mutations in biological systems. Combining theoretical calculations and molecular recognition experiments demonstrated that these “mutations” have an impact on the hydrophobicity and charge distribution of the hosts, consequently significantly influencing molecular *** is crucial for understanding the intricate mechanisms of molecular-level interactions in biological receptors.

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高校基础课程教学质量评价模型的实证研究

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北京邮电大学学报（社会科学版） 2017年第2期19卷 103-110页

作者：张琳魏翼飞闫浩王铁军李鹤北京邮电大学理学院北京100876

基础课教学评价是提升教学质量的重要手段,评价指标的主次地位、不同指标的评价差异是分析评价结果的关键问题。基于北京邮电大学历年基础课程的"网上评教"数据以及独立问卷调查结果数据,借助因子分析方法,得到如下结论:课堂教学是评价... 详细信息

基础课教学评价是提升教学质量的重要手段,评价指标的主次地位、不同指标的评价差异是分析评价结果的关键问题。基于北京邮电大学历年基础课程的"网上评教"数据以及独立问卷调查结果数据,借助因子分析方法,得到如下结论:课堂教学是评价的主要指标,课外教学的地位次之,反映了课堂教学在评价中的主体地位以及当前教育对课外教学的投入偏弱等现象。独立问卷调查结果反映了大学生对"科研与前沿"和"思维训练"等指标充满期待和需求。

关键词：教学质量评价指标基础课程因子分析高校

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