检索结果-南通市图书馆

Defence Technology（防务技术） 2021年第4期17卷 1471-1485页

作者： Teng Chen yi-wen hu Cai Zhang Zhao-jian Gao School of Material and Chemical Engineering Xuzhou University of TechnologyXuzhouJiangsuPR China Xi’an Modern Chemistry Research Institute Xi’anShaanxiPR China Xuzhou University of Technology XuzhouJiangsuPR China

As a main oxidizer in solid composite propellants,ammonium perchlorate(AP)plays an important role because its thermal decomposition behavior has a direct influence on the characteristic of solid composite *** improve the performance of solid composite propellant,it is necessary to take measures to modify the thermal decomposition behavior of *** recent years,transition metal oxides and carbon-supported transition metal oxides have drawn considerable attention due to their extraordinary catalytic *** this review,we highlight strategies to enhance the thermal decomposition of AP by tuning morphology,varying the types of metal ion,and coupling with carbon *** enhanced catalytic performance can be ascribed to synergistic effect,increased surface area,more exposed active sites,and accelerated electron transportation and so *** mechanism of AP decomposition mixed with catalyst has also been briefly ***,a conclusive outlook and possible research directions are suggested to address challenges such as lacking practical application in actual formulation of solid composite propellant and batch manufacturing.

关键词： Transition metal oxides Carbon-supported transition metal oxides Catalyst Ammonium perchlorate Thermal decomposition

Effect of electromagnetic parameters on melt flow and heat transfer of AZ80 Mg alloy during differential phase electromagnetic DC casting based on numerical simulation

在线全文

学校读者我要写书评

暂无评论

China Foundry 2022年第3期19卷 191-200页

作者： Yong-hui Jia Cheng-lu hu Qi-chi Le wen-yi hu Key Laboratory of Electromagnetic Processing of Materials Ministry of EducationNortheastern UniversityShenyang 110819China Longyan University College of Chemistry and Materials ScienceLongyan 364012FujianChina

Based on multi-physical field coupling numerical simulation method,magnetic field distribution,melt flow,and heat transfer behavior of aΦ300 mm AZ80 alloy billet during differential phase electromagnetic DC casting(DP-EMC)with different electromagnetic parameters were *** results demonstrate that the increase in current intensity only changes the magnitude but does not change the Lorentz force's distribution *** maximum value of the Lorentz force increases linearly followed by an increase in current *** the frequency increases,the Lorentz force's r component remains constant,and the z component decreases *** change in current intensity correlates with the melt oscillation and convection intensity positively,as well as the liquid sump temperature *** does not mean that the higher the electric current,the better the metallurgical quality of the billet.A lower frequency is beneficial to generate a more significant melt flow and velocity fluctuation,which is helpful to create a more uniform temperature *** DP-EMC parameters for aΦ300 mm AZ80 Mg alloy are 10-20 Hz frequency and 80-100 A current intensity.

关键词： heat transfer melt flow differential phase electromagnetic field DC casting Mg alloy

Optomechanical sensing with on-chip microcavities

在线全文

学校读者我要写书评

暂无评论

Frontiers of physics 2013年第5期8卷 475-490页

作者： yi-wen hu Yun-Feng Xiao Yong-Chun Liu Qihuang Gong State Key Laboratory for Artificial Microstructure and Mesoscopic Physics School of Physics Peking University Beijing 100871 China

The coupling between optical and mechanical degrees of freedom has been of broad interest for a long time. However, it is only until recently, with the rapid development of optical mierocavity research, that we are able to manipulate and utilize this coupling process. When a high Q microeavity couples to a mechanical resonator, they can consolidate into an optomeehanieal system. Benefitting from the unique characteristics offered by optomeehanical coupling, this hybrid system has become a promising platform for ultrasensitive sensors to detect displacement, mass, force and acceleration. In this review, we introduce the basic physical concepts of cavity optomechanies, and describe some of the most typical experimental cavity optomechanical systems for sensing applications. Finally, we discuss the noise arising from various sources and show the potentiality of optomechanical sensing towards quantum-noise-limited detection.

关键词： optical microcavities mechanical resonators cavity optomechanics optical sensing,integrated photonics

Time course analysis of sensory axon regeneration in vivo by directly tracing regenerating axons

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2020年第6期15卷 1160-1165页

作者： Yan Gao yi-wen hu Run-Shan Duan Shu-Guang Yang Feng-Quan Zhou Rui-ying Wang Guilin Medical University GuilinGuangxi Zhuang Autonomous RegionChina Department of Orthopedic Surgery Affiliated Hospital of Guilin Medical UniversityGuilinGuangxi Zhuang Autonomous RegionChina Department of Orthopedics Henan Provincial People’s HospitalPeople’s Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina Department of Orthopedic Surgery Johns Hopkins University School of MedicineBaltimoreMDUSA

Most current studies quantify axon regeneration by immunostaining regeneration-associated proteins,representing indirect measurement of axon lengths from both sensory neurons in the dorsal root ganglia and motor neurons in the spinal *** recently developed method of in vivo electroporation of plasmid DNA encoding for enhanced green fluorescent protein into adult sensory neurons in the dorsal root ganglia provides a way to directly and specifically measure regenerating sensory axon lengths in whole-mount nerves.A mouse model of sciatic nerve compression was established by squeezing the sciatic nerve with *** DNA carrying enhanced green fluorescent protein was transfected by ipsilateral dorsal root ganglion electroporation 2 or 3 days before *** distribution of dorsal root or sciatic nerve was observed by confocal *** 12 and 18 hours,and 1,2,3,4,5,and 6 days of injury,lengths of regenerated axons after sciatic nerve compression were measured using green fluorescence ***-related protein caspase-3 expression in dorsal root ganglia was determined by western blot *** found that in vivo electroporation did not affect caspase-3 expression in dorsal root *** root ganglia and sciatic nerves were successfully removed and subjected to a rapid tissue clearing *** soma in dorsal root ganglia expressing enhanced green fluorescent protein or fluorescent dye-labeled microRNAs were imaged after tissue *** results facilitate direct time course analysis of peripheral nerve axon *** study was approved by the Institutional Animal Care and Use Committee of Guilin Medical University,China(approval ***201503010)on March 7,2014.

关键词： axon regeneration cell apoptosis dorsal root ganglion in vivo electroporation micro RNAs peripheral nervous system sciatic nerve tissue clearing

Lipoprotein(a)variability is associated with mean follow-up Creactive protein in patients with coronary artery disease following percutaneous coronary intervention

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第35期10卷 12909-12919页

作者： Si-Si Zhang wen-yi hu yi-Jing Li Juan Yu Shang Sang Zakareya M Alsalman Da-Qi Xie Department of Cardiology Ningbo Ninth HospitalNingbo 315300Zhejiang ProvinceChina

BACKGROUND Increased lipoprotein(a)[lp(a)]has proinflammatory effects,which increase the risk of coronary artery ***,the association between lp(a)variability and follow-up C-reactive protein(CRP)level in patients undergoing percutaneous coronary intervention(PCI)has not been *** To explore the association between lp(a)variability and mean CRP levels within the 1st year *** Results of lp(a)and CRP measurements from at least three follow-up visits of patients who had received PCI were retrospectively *** deviation(SD),coefficient of variation(CV),and variability independent of the mean(VIM)are presented for the variability for lp(a)and linear regression analysis was conducted to correlate lp(a)variability and mean follow-up CRP *** relationship of lp(a)variability and inflammation status was analyzed by restricted cubic spline ***,exploratory analysis was performed to test the consistency of results in different *** A total of 2712 patients were *** with higher variability of lp(a)had a higher level of mean follow-up CRP(P<0.001).lp(a)variability was positively correlated with the mean follow-up CRP(SD:β=0.023,P<0.001;CV:β=0.929,P<0.001;VIM:β=1.648,P<0.001)by multivariable linear regression *** analysis showed that the positive association remained consistent in most *** Lp(a)variability correlated with mean follow-up CRP level and high variability could be considered an independent risk factor for increased post-PCI CRP level.

关键词： Lipoprotein(a) Variability C-reactive protein Coronary artery disease Percutaneous coronary intervention

Reliability of pressure cuff induced transient limb ischemia in conscious rabbits

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2014年第11期127卷 2138-2142页

作者： Zhang Nanrong Zheng Wanjun wen yi hu Qiongyu Jin Sanqing Department of Anesthesia Sixth Affiliated Hospital Sun Yat-sen University Guangzhou Guangdong 510655 China

Background The protective effects of transient limb ischemia （TLI） induced by several cycles of intermittent pressure cuff inflation and deflation for a period have been widely investigated,however the reliability of this protocol has not been clearly *** study aimed to investigate the reliability of pressure cuff induced TLI in conscious *** Eight New Zealand rabbits were subjected to TLI without *** consisted of 3 cycles of ischemia and reperfusion induced by inflating the cuff placed on the left lower limb to 200 mmHg for 5 minutes followed by deflating the cuff for 5 *** color,pulse oxygen saturation （SpO2）,pulse rate （PR）,plethysmogram waveform （Pleth）,and ultrasound detection of the blood flow in the extremity distal to the ischemic segment were observed to confirm ischemia and reperfusion during *** frequency of severe limb movement during TLI was also recorded to assess the amenability of this protocol in conscious *** The skin color of the extremity distal to the ischemic segment changed from bright red to dark purple after inflating the cuff to 200 mmHg,and returned to normal after cuff ***,PR and SpO2 disappeared during ischemia and restored during reperfusion in the *** flow of the left posterior tibial artery was completely blocked by a pressure of 200 mmHg during ischemia,and recovered immediately after cuff *** frequency of severe limb movement in supine position was higher than that in prone position （P〈0.05）,but there was no severe limb movement that could result in disturbance to ischemia when the rabbits were placed in prone *** Pressure cuff inflating to 200 mmHg for 5 minutes and deflating for 5 minutes is a reliable regimen to induce TLI in conscious rabbits.

关键词： transient limb ischemia reliability pressure cuff pulse oxygen saturation vascular ultrasound

Tissue-targeting lead generation and optimization from random and directed screening of technetium-99m labeled tripeptide complex libraries in vivo

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2006年第17期119卷 1435-1443页

作者： ZENG Jun LIU Ci-yi XIE wen-hui hu Si-long JIN Mu-xiu Department of Nuclear Medicine Shanghai Chest HospitalShanghai Jiao-Tong University 241 Hui-hai Road Shanghai200030 China

Background Screening libraries against a molecular target in vitro are idealized models that cannot reflect the real state in vivo where biomolecules coexist and interact. C-terminal amide tripeptides labelled with Technetium-99m can provide a unique noninvasive approach to trace a large number of compounds in vivo. Methods The C-terminal amide tripeptide libraries were synthesized on Rink Amide-MBHA resin using iterative and pooling protocol. Technetium （V） oxo core [TcO^3＋] was bound to each tripeptide via 4 deprotonated nitrogen atoms to form a library of 8000 ^99mTc tripeptoid complexes. The radiocombinatorial screening （RCS） in vivo was carried out on SD rats and A549 tumour bearing mice. Results Signals of tissue distribution and metabolism of libraries were recorded by counting or imaging and tissue targeting leads identified by both random and directed RCS. Among them, ^99mTc RPA, ^99mTc VIG and ^99mTC RES had specific tissue targeting in kidney, liver and tumour respectively. The percent injected dose per gram tissue of ^99mTc labelled leads in their target tissue was highly structure dependent. Because the nontarget tissue binding and the metabolism of ^99mTc tripeptoid sublibraries were simultaneously monitored successfully by RCS, the interference of background activity was limited to the lowest level. Optimization of renal function agent from the labelled libraries was carried out by directed screening. ^99mTc DSG was finally identified the most promising agent for renal function studies. Conclusions RCS in vivo is a powerful tool for the discovery of tissue targeting drugs. The potential screening bias is probably the major limitation of labelled libraries.

关键词： 99mTc labeled tripeptide libraries in vivo random screening directed screening

Wave effect of gravitational waves intersected with a microlens field Ⅱ:An adaptive hierarchical tree algorithm and population study

在线全文

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 241-254页

作者： Xikai Shan Guoliang Li Xuechun Chen wen Zhao Bin hu Shude Mao Department of Astronomy Tsinghua University Purple Mountain Observatory Chinese Academy of Sciences Institute for Frontier in Astronomy and Astrophysics Beijing Normal University School of Physics and Astronomy Beijing Normal University School of Astronomy and Space Science University of Science and Technology of China CAS Key Laboratory for Researches in Galaxies and Cosmology Department of Astronomy University of Science and Technology of ChinaChinese Academy of Sciences

The gravitational lensing wave effect generated by a microlensing field embedded in a lens galaxy is an inevitable phenomenon in strong lensed gravitational waves （SLGWs）.This effect presents both challenges and opportunities for the detection and application of ***,investigating this wave effect requires computing a complete diffraction integral over each microlens in the *** is extremely time-consuming due to the large number of microlenses （10～3-10～6）.Therefore,simply adding all the microlenses is ***,the complexity of the time delay surface makes the lens plane resolution a crucial factor in controlling numerical *** this paper,we propose a trapezoid approximation-based adaptive hierarchical tree algorithm to meet the challenges of calculation speed and *** find that this algorithm accelerates the calculation by four orders of magnitude compared to the simple adding method and is one order of magnitude faster than the fixed hierarchical tree algorithm proposed for electromagnetic *** importantly,our algorithm ensures controllable numerical errors,increasing confidence in the *** with our previous work （***.66,239511,2023）,this paper addresses all numerical issues,including integral convergence,precision,and computational time1).Finally,we conducted a population study on the microlensing wave effect of SLGWs using this algorithm and found that the microlensing wave effect cannot be ignored,especially for Type II SLGWs （from saddle position of the time delay surface） due to their intrinsic geometric structures and their typical intersection with a denser microlensing ***,more than 33%（11%） of SLGWs have a mismatch larger than 1%（3%） compared to the unlensed ***,we found that the mismatch between signal pairs in a doubly imaged GW is generally larger than 10-3,and 61%（25%） of signal pairs have a mismatch larger than 1%（3%）.Therefo

关键词： gravitational lensing diffractional integral algorithm gravitational wave

Repetitive transcranial magnetic stimulation in Alzheimer’s disease:effects on neural and synaptic rehabilitation

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第2期20卷 326-342页

作者： yi Ji Chaoyi Yang Xuerui Pang yibing Yan Yue Wu Zhi Geng wenjie hu Panpan hu Xingqi Wu Kai Wang Department of Neurology The First Affiliated Hospital of Anhui Medical UniversityHefeiAnhui ProvinceChina Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders HefeiAnhui ProvinceChina Collaborative Innovation Center of Neuropsychiatric Disorders and Mental Health HefeiAnhui ProvinceChina Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefeiAnhui ProvinceChina Department of Psychology and Sleep Medicine The Second Affiliated Hospital of Anhui Medical UniversityHefeiAnhui ProvinceChina

Alzheimer’s disease is a neurodegenerative disease resulting from deficits in synaptic transmission and *** Alzheimer’s disease brain tends to be hyperexcitable and hypersynchronized,thereby causing neurodegeneration and ultimately disrupting the operational abilities in daily life,leaving patients *** transcranial magnetic stimulation is a cost-effective,neuro-modulatory technique used for multiple neurological *** the past two decades,it has been widely used to predict cognitive decline;identify pathophysiological markers;promote neuroplasticity;and assess brain excitability,plasticity,and *** has also been applied to patients with dementia,because it can yield facilitatory effects on cognition and promote brain recovery after a neurological ***,its therapeutic effectiveness at the molecular and synaptic levels has not been elucidated because of a limited number of *** study aimed to characterize the neurobiological changes following repetitive transcranial magnetic stimulation treatment,evaluate its effects on synaptic plasticity,and identify the associated *** review essentially focuses on changes in the pathology,amyloidogenesis,and clearance pathways,given that amyloid deposition is a major hypothesis in the pathogenesis of Alzheimer’s *** mechanisms associated with repetitive transcranial magnetic stimulation procedures and different pathways mediating gene transcription,which are closely related to the neural regeneration process,are also ***,we discuss the outcomes of animal studies in which neuroplasticity is modulated and assessed at the structural and functional levels by using repetitive transcranial magnetic stimulation,with the aim to highlight future directions for better clinical translations.

关键词： Alzheimer’s disease amyloid deposition apoptotic mechanisms biomarker neural regeneration neurodegeneration repetitive transcranial magnetic stimulation synaptic plasticity

Porous Organic Cage‑Based Quasi‑Solid‑State Electrolyte with Cavity‑Induced Anion‑Trapping Effect for Long‑Life Lithium Metal Batteries

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第2期17卷 376-386页

作者： Wei-Min Qin Zhongliang Li wen‑Xia Su Jia‑Min hu Hanqin Zou Zhixuan Wu Zhiqin Ruan Yue‑Peng Cai Kang Li Qifeng Zheng School of Chemistry South China Normal UniversityGuangzhou 510006People’s Republic of China Key Laboratory of Functional Metal‑Organic Compounds of hunan Province College of Chemistry and Material ScienceHengyang Normal UniversityHengyang 421008People’s Republic of China Guangzhou Key Laboratory of Energy Conversion and Energy Storage Materials Guangzhou 510006People’s Republic of China

Porous organic cages(POCs)with permanent porosity and excellent host–guest property hold great potentials in regulating ion transport behavior,yet their feasibility as solid-state electrolytes has never been testified in a practical ***,we design and fabricate a quasi-solid-state electrolyte(QSSE)based on a POC to enable the stable operation of Li-metal batteries(LMBs).Benefiting from the ordered channels and cavity-induced anion-trapping effect of POC,the resulting POC-based QSSE exhibits a high Li+transference number of 0.67 and a high ionic conductivity of 1.25×10^(−4) S cm^(−1) with a low activation energy of 0.17 *** allow for homogeneous Li deposition and highly reversible Li plating/stripping for over 2000 *** a proof of concept,the LMB assembled with POC-based QSSE demonstrates extremely stable cycling performance with 85%capacity retention after 1000 ***,our work demonstrates the practical applicability of POC as SSEs for LMBs and could be extended to other energy-storage systems,such as Na and K batteries.

关键词： Porous organic cage Cavity-induced anion-trapping Quasi-solid-state electrolyte Homogeneous Li+flux Lithium metal battery