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Formation of hierarchical Co-decorated Mo_(2)C hollow spheres for enhanced hydrogen evolution

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Rare Metals 2021年第10期40卷 2785-2792页

作者： yi-Zhong Wang yi-ming ding Cai-Hong Zhang Bo-Wen Xue Nian-Wu Li Le Yu State Key Lab of Organic-Inorganic Composites Beijing University of Chemical TechnologyBeijing 100029China

Water electrolysis has been regarded as a promising technology to produce clean hydrogen fuel with high purity. However, large-scale water electrolysis has been greatly hindered due to the lack of non-noble metal catalysts with high catalytic performance. Benefitting from unique hollow structures with large surface area and adjustable chemical compositions, hollow design plays an important role in improving the electrocatalytic performance for hydrogen evolution reaction(HER). Herein, we report an effective multi-step strategy to prepare hierarchical Co-decorated Mo_(2)C hollow spheres(CMCHSs) as electrocatalyst for HER. To be specific, the preparation process involves a metal-chelated polymerization and a subsequent surface modulation process. Owing to the unique hollow structure and incorporation of Co species,the as-prepared CMCHSs demonstrate largely enhanced HER performance with a low overpotential of 139 mV at the current density of 10 m A·cm^(-2) and good cycling durability in acid. The present research work highlights a new feasible strategy for the design of HER electrocatalyst via hollow designs and surface engineering.

关键词： Mo_(2)C Hollow design Surface modulation Hydrogen evolution reaction

Authors’Reply:Pre-operative imaging of the supraclavicular artery island flap plays a vital role in the flap design

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Chinese Medical Journal 2021年第16期134卷 2015-2016页

作者： Jing Zhou yi-ming ding Meng-Jiao Zhou Yun-Xun Kuang Ting-Yao Ma Xiao-Hong Chen Department of Otolaryngology Head and Neck Surgery Beijing Tongren HospitalCapital Medical UniversityBeijing 100005China.

Thank you very much for reviewing the case report carefully and proposing meaningful comments on evaluating angiosome of the supraclavicular *** view of your opinions and based on our clinical experience,we hereby rep... 详细信息

关键词： operative island supra

Two New r-process-enhanced Stars with [Fe/H] >-0.6 dex from the LAMOST-MRS Survey

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Research in Astronomy and Astrophysics 2022年第7期22卷 109-117页

作者： Xiao-Jin Xie Jian-Rong Shi Tian-Lu Chen Hong-Liang Yan Tian-yi Chen Kai-Ke Pan Chun-Qian Li Shuai Liu Qi Gao Tai-Sheng Yan ming-yi ding Department of Physics College of ScienceTibet UniversityLhasa 850000China Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China Apache Point Observatory SunspotNew Mexico 88349USA Astronomy Department New Mexico State UniversityLas CrucesNew Mexico 88003USA

We report the discovery of two r-process-enhanced stars with [Fe/H]>-0.6 dex selected from the Large Sky Area Multi-Object Fiber Spectroscopic Telescope(LAMOST) *** candidate stars have been selected from the LAMOST medium-resolution(R~ 7500) spectroscopic survey,and the follo wed-up high signal-to-noise ratio and high-resolution(R~31,500) spectra are obtained with the ARC Echelle Spectrograph mounted on the3.5 m telescope at the Apache Point Observatory,which allow us for the determination of stellar atmospheric parameters and abundances of 20 *** these three r-process-enhanced candidate stars,TYC 1710-933-1 and TYC 2858-372-1 have [Eu/Fe] higher than 0.3 dex and [Ba/Eu] lower than 0.0 dex,thus,can be identified as new r-process-enhanced *** 2858-372-1 shows similar r+s-process pattern to the *** 1710-933-1 presents enhancement of the r-process elements of Nd and *** work indicates that the enrichment mechanisms of the heavy neutron-capture elements are complicated for metal-rich stars.

关键词： stars:abundances stars:chemically peculiar stars:fundamental parameters

Diagnostic Significance of Intraoperative Ultrasound Contrast in Evaluating the Resection Degree of Brain Glioma By Transmission Electron Microscopic Examination

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Chinese Medical Journal 2015年第2期128卷 186-190页

作者： Shu-Qing Yu Ji-Sheng Wang Si-Yuan Chen Xiang-ming Liu Yan Li yi-ming ding Xiao-Ya Li yi-Lin Sun Hui Chen Department of Neurosurgery Beijing Tiantan Hospital Capital Medical University Beijing 100050 China Department of Ultrasound Beijing Tiantan Hospital Capital Medical University Beijing 100050 China Department of Electronic Microscopy Beijing Tiantan Hospital Capital Medical University Beijing 100050 China Department of Statistics Beijing Tiantan Hospital Capital Medical University Beijing 100050 China

Background：Contrast-enhanced ultrasound is a dynamic and continuous modality providing real-time view of vascularization and flow distribution patterns of different organs and *** order to evaluate the diagnostic significance of intraoperative contrast-enhanced ultrasound in assessing the resection degree of brain glioma by transmission electron microscopic （TEM） examination,it is important to have specific knowledge about contrast-enhanced ***：Ultrasound contrast was applied in operations of 120 cases of brain glioma,to evaluate the degree of tumor *** tissues were obtained the suspicious residual tumors surrounding the tumor *** sensitivity and specificity of the residual tumors were determined by the intraoperative ultrasound contrast according to TEM examination ***：There were 44 cases of low-grade gliomas and 76 cases of high-grade *** hundred and sixty biopsy tissues were *** sensitivity of intraoperative ultrasound contrast in diagnosing the residual tumor was 62.2%,while the specificity degree of it was 92.8%.The consistency coefficient of the ultrasound contrast diagnosis and TEM examination results was 0.584 （Kappa =0.584）,which was between 0.4 and 0.6,therefore it was of medium ***：Intraoperative ultrasound contrast was of a high sensitivity and specificity in evaluating the excision degree of *** consistency of the residual tumor rate detected,respectively,by ultrasound contrast and TEM examination was of medium *** application of intraoperative ultrasound contrast can improve the resection rate of brain glioma.

关键词： Brain Gliona Intra-sutgery Transmissionelectron Microscopic Resection Degree: UltrasoundContrast

Application of bilateral supraclavicular artery island flaps in the repair of hypopharyngeal and cervical skin defects:a case report

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Chinese Medical Journal 2020年第11期133卷 1380-1382页

To the Editor:In advanced head and neck malignancies,especially in patients who relapse after comprehensive treatment such as a history of neck surgery or radiotherapy,tumors can simultaneously invade both the mucosa and *** of penetrating defects formed after tumor resection must achieve the following goals:(1)Reconstruction of the digestive tract to restore swallowing function.(2)Provide soft tissue for repair of important structures in the neck,that is,to re-build the skin of the *** used bilateral supraclavicular artery island flaps to repair a large area of skin with mucosal defects in the neck of a patient with advanced laryngeal malignancy after surgery,and with satisfactory post-operative results.

关键词： surgery island supra

Clinical significance and influencing factors of linked color imaging technique in real-time diagnosis of active Helicobacter pylori infection

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Chinese Medical Journal 2019年第20期132卷 2395-2401页

作者： Li Wang Xiang-Chun Lin Hai-Long Li Xue-Song Yang Lei Zhang Xin Li Peng Bai Yan Wang Xue Fan yi-ming ding ding Department of Gastroenterology Peking University International HospitalBeijing 102206China

Background:Determining the Helicobacter pylori (H. pylori) infection state during the gastroscopic process is important but still challenging. The linked color imaging (LCI) technique might emphasize the mucosal color change after H. pylori infection, which might help the diagnosis. In the present study, we aimed to compare the LCI technique with traditional white light imaging (WLI) endoscopy for diagnosing active H. pylori ***:We collected and analyzed gastroscopic images from 103 patients in our hospital from November 2017 to March 2018, including both LCI and WLI modes. All images were randomly disordered and independently evaluated by four endoscopists who were blinded to the H. pylori status of patients. In addition, the H. pylori state was determined by both rapid urease test and pathology staining. The sensitivity, specificity, positive prediction value (PPV), and negative prediction value (NPV) were calculated for the detection of H. pylori infection. Moreover, the kappa value and interclass correlation coefficient (ICC) were used to evaluate the inter-observer variety by SPSS 24.0 ***:Of the 103 enrolled patients, 27 of them were positive for H. pylori infection, while the 76 patients were negative. In total, 388 endoscopic images were selected, including 197 WLI and 191 LCI. The accuracy rate for H. pylori evaluation in the corpus LCI group was significantly higher than other groups (81.2% vs. 64.3%-76.5%, χ2 = 34.852, P < 0.001). Moreover, the corpus LCI group had the optimal diagnostic power with the sensitivity of 85.41% (95% confidence interval [CI]: 76.40%-91.51%), the specificity of 79.71% (95% CI: 74.38%-84.19%), the PPV of 59.42% (95% CI: 50.72%-67.59%), and the NPV of 94.02% (95% CI: 89.95%-96.56%), respectively. The kappa values between different endoscopists were higher with LCI than with WLI (0.433-0.554 vs. 0.331-0.554). Consistently, the ICC value was also higher with LCI than with WLI (0.501 [95% CI: 0.429-0.574]

关键词： Helicobacter pylori Image enhancement technique Linked color imaging Real-time diagnosis

PI3K/AKT signaling and neuroprotection in ischemic stroke:molecular mechanisms and therapeutic perspectives

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Neural Regeneration Research 2025年第10期20卷 2758-2775页

作者： Tianlong Liu Xiaolin Li Xiaowei Zhou Wei Chen Aidong Wen Minna Liu yi ding Department of Pharmacy Xijing HospitalFourth Military Medical UniversityXi’anShaanxi ProvinceChina Department of Pharmacy The 940 Hospital of Joint Logistics Support Forces of Chinese PLALanzhouGansu ProvinceChina Department of Pharmacy The 944 Hospital of Joint Logistics Support Forces of Chinese PLAJiuquanGansu ProvinceChina Department of Nephrology The 940 Hospital of Joint Logistics Support Forces of Chinese PLALanzhouGansu ProvinceChina

It has been reported that the PI3K/AKT signaling pathway plays a key role in the pathogenesis of ischemic *** a result,the development of drugs targeting the PI3K/AKT signaling pathway has attracted increasing attention from *** article reviews the pathological mechanisms and advancements in research related to the signaling pathways in ischemic stroke,with a focus on the PI3K/AKT signaling *** key findings include the following:(1)The complex pathological mechanisms of ischemic stroke can be categorized into five major types:excitatory amino acid toxicity,Ca^(2+)overload,inflammatory response,oxidative stress,and apoptosis.(2)The PI3K/AKT-mediated signaling pathway is closely associated with the occurrence and progression of ischemic stroke,which primarily involves the NF-κB,NRF2,BCL-2,mTOR,and endothelial NOS signaling pathways.(3)Natural products,including flavonoids,quinones,alkaloids,phenylpropanoids,phenols,terpenoids,and iridoids,show great potential as candidate substances for the development of innovative anti-stroke medications.(4)Recently,novel therapeutic techniques,such as electroacupuncture and mesenchymal stem cell therapy,have demonstrated the potential to improve stroke outcomes by activating the PI3K/AKT signaling pathway,providing new possibilities for the treatment and rehabilitation of patients with ischemic *** investigations should focus on the direct regulatory mechanisms of drugs targeting the PI3K/AKT signaling pathway and their clinical translation to develop innovative treatment strategies for ischemic stroke.

关键词： apoptosis autophagy inflammation ischemic stroke neuroprotection oxidative stress pathogenesis phosphatidylinositol 3-kinase protein kinase B therapeutics