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一种基于移动Ad hoc网络的安全路由策略

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计算机应用研究 2005年第10期22卷 139-141页

作者：蒋毅史浩山西北工业大学电子信息学院陕西西安710072

移动Ad hoc网是一种新兴的无线移动自组织网络,其路由安全机制与传统网络的路由安全机制有很大差异。在分析Ad hoc网络的特点和局限性的基础上,从各网络节点易受攻击、俘获,各网络节点之间不可信赖的角度出发,引入了可信任第三方的信任... 详细信息

移动Ad hoc网是一种新兴的无线移动自组织网络,其路由安全机制与传统网络的路由安全机制有很大差异。在分析Ad hoc网络的特点和局限性的基础上,从各网络节点易受攻击、俘获,各网络节点之间不可信赖的角度出发,引入了可信任第三方的信任分散策略,提出了一种新的移动Ad hoc网络的安全路由策略,解决了节点之间身份的分布式认证,为节点之间的通信提供了极为安全的路由策略。

关键词：移动Ad hoc网络门限方案分布式认证安全路由

Origin of the Novel Magnetoresistance Oscillation of the Two-Dimensional Electron Gas in Al_(x)Ga_(l-x)N/GaN Heterostructures

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Chinese Physics Letters 2001年第12期18卷 1641-1643页

作者： ZHENG Ze-Wei SHEN Bo jiang Chun-Ping ZHANG Rong shi yi ZHENG You-Dou ZHENG Guo-Zhen GUO Shao-Ling CHU Jun-hao National Laboratory of Solid State Microstructures and Department of Physics Nanjing UniversityNanjing 210093 National Laboratory for Infrared Physics Shanghai Institute of Technical PhysicsChinese Academy of SciencesShanghai 200083

In the magnetotransport measurements of the two-dimensional electron gas (2DEG) in modulation-doped Al_(0.22)Ga_(0.7)sN/C heterostructures, a new magnetoresistance oscillation of the 2DEG is observed at low magnetic fields when the Al_(0.22)Ga_(0.7)sN layer on GaN is partially relaxed. It is thought that the misfit dislocations induced by the partially relaxed Al_(0.22)Ga_(0.7)sN layer modulate the distribution of the piezoelectric polarization-induced charges at the Al0.22Ga0.7sN/GaN heterointerface, and thus produce a strong modulation potential at the heterointerface. The strong modulation potential results in the novel magnetoresistance oscillation of the 2DEG at low magnetic fields.

关键词： N/Ga polarization relaxed

Metformin accelerates bone fracture healing by promoting type H vessel formation through inhibition of YAP1/TAZ expression

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Bone Research 2023年第3期11卷 625-637页

作者： Zhe Ruan hao yin Teng-Fei Wan Zhi-Rou Lin Shu-shan Zhao Hai-Tao Long Cheng Long Zhao-Hui Li Yu-Qi Liu hao Luo Liang Cheng Can Chen Min Zeng Zhang-Yuan Lin Rui-Bo Zhao Chun-Yuan Chen Zhen-Xing Wang Zheng-Zhao Liu Jia Cao yi-yi Wang Ling Jin yi-Wei Liu Guo-Qiang Zhu Jing-Tao Zou jiang-shan Gong yi Luo yin Hu Yong Zhu Hui Xie Department of Orthopedics Xiangya HospitalCentral South UniversityChangshaHunan 410008China Movement System Injury and Repair Research Center Xiangya HospitalCentral South UniversityChangshaHunan 410008China Hunan Key Laboratory of Angmedicine ChangshaHunan 410008China Angmedicine Research Center of Central South University ChangshaHunan 410008China The First Affiliated Hospital Department of Metabolism and EndocrinologyHengyang Medical SchoolUniversity of South ChinaHengyangHunan 421001China National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangshaHunan 410008China

Due to increasing morbidity worldwide,fractures are becoming an emerging public health *** study aimed to investigate the effect of metformin on the healing of osteoporotic as well as normal *** H vessels have recently been identified as a bone-specific vascular subtype that supports ***,we show that metformin accelerated fracture healing in both osteoporotic and normal ***,metformin promoted angiogenesis in vitro under hypoxia as well as type H vessel formation throughout fracture ***,metformin increased the expression of HIF-1α,an important positive regulator of type H vessel formation,by inhibiting the expression of YAP1/TAZ in calluses and hypoxia-cultured human microvascular endothelial cells(HMECs).The results of HIF-1αor YAP1/TAZ interference in hypoxia-cultured HMECs using si RNA further suggested that the enhancement of HIF-1αand its target genes by metformin is primarily through YAP1/TAZ ***,overexpression of YAP1/TAZ partially counteracted the effect of metformin in promoting type H vessel-induced angiogenesis-osteogenesis coupling during fracture *** summary,our findings suggest that metformin has the potential to be a therapeutic agent for fractures by promoting type H vessel formation through YAP1/TAZ inhibition.

关键词： YAP1 healing fracture

The Huashan risk calculators performed better in prediction of prostate cancer in Chinese population： a training study followed by a validation study

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Asian Journal of Andrology 2016年第6期18卷 925-929页

作者： yi-Shuo Wu Ning Zhang Sheng-Hua Liu Jian-Feng Xu shi-Jun Tong Ye-Hua Cai Li-Min Zhang Pei-De Bai Meng-Bo HU hao-Wen jiang Rong Na Qiang Ding ying-hao Sun Department of Urology Huashan Hospital Fudan University Shanghai China Urology Research Center Fudan University Shanghai China Department of Ultrasonic Huashan Hospital Fudan University Shanghai China NorthShore University HeatthSystem Evanston IL USA Department of Urology Changhai Hospital The Second Military Medical University Shanghai China

The performances of the Prostate Cancer Prevention Trial （PCPT） risk calculator and other risk calculators for prostate cancer （PCa） prediction in Chinese populations were poorly understood. We performed this study to build risk calculators （Huashan risk calculators） based on Chinese population and validated the performance of prostate-specific antigen （PSA）, PCPT risk calculator, and Huashan risk calculators in a validation cohort. We built Huashan risk calculators based on data from 1059 men who underwent initial prostate biopsy from January 2006 to December 2010 in a training cohort. Then, we validated the performance of PSA, PCPT risk calculator, and Huashan risk calculators in an observational validation study from January 2011 to December 2014. All necessary clinical information were collected before the biopsy. The results showed that Huashan risk calculators 1 and 2 outperformed the PCPT risk calculator for predicting PCa in both entire training cohort and stratified population （with PSA from 2.0 ng ml^-1 to 20.0 ng ml^-1）. In the validation study, Huashan risk calculator 1 still outperformed the PCPT risk calculator in the entire validation cohort （0.849 vs 0.779 in area under the receiver operating characteristic curve [AUC]） and stratified population. A considerable reduction of unnecessary biopsies （approximately 30%） was also observed when the Huashan risk calculators were used. Thus, we believe that the Huashan risk calculators （especially Huashan risk calculator 1） may have added value for predicting PCa in Chinese population. However, these results still needed further evaluation in larger populations.

关键词： biopsy China prostate cancer prostate-specific antigen risk calculator

Validating the accuracy of a multifunctional smartwatch sphygmomanometer to monitor blood pressure

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Journal of Geriatric Cardiology 2022年第11期19卷 843-852页

作者： Li yi Zhong-Hua LV Shun-ying HU Yu-Qi LIU Jia-Bing YAN Hui Zhang Hong-Bao LI Qin CHEN Yue-Yang LI Yu-Fan jiang hao ZHOU Mu-Ding LI Run-Du CHEN Xiao-Long LI shan-shan ZHOU Yun-Dai CHEN Department of Cardiology the First Medical CentreChinese PLA General HospitalBeijingChina Department of Cardiology the Sixth Medical CentreChinese PLA General HospitalBeijingChina Medical School of Chinese PLA BeijingChina Huawei Device Co. Ltd.ShenzhenChina

BACKGROUND Hypertension is the most modifiable factor associated with cardiovascular events and *** conventional blood pressure(BP) meter method is simple but is limited in terms of real-time monitoring abnormal ***,the development of a multifunction smartwatch(HUAWEI WATCH D) sphygmomanometer could significantly improve integrated BP *** We enrolled 361 subjects from Chinese PL A General Hospital,Beijing,China to validate the accuracy of the smartwatch versatile sphygmomanometer using ISO 81060-2:*** and ambulatory BP accuracy of the smartwatch were compared with gold standard clinical sphygmomanometers using ISO 81060-2:2018 guidelines,the accuracy of 24 h systolic blood pressure(SBP) circadian rhythm monitoring,and diurnal high SBP alert for this smartwatch were assessed using a confusion matrix ***,we analyzed online users of different ages for *** Eighty-five subjects underwent resting BP measurements;the mean resting BP differences between two devices were-0.683±6.203 mmHg(SBP)(P=0.723) and 1.628±5.028 mmHg(diastolic blood pressure,DBP)(P=0.183).In 35 subjects’ ambulatory BP measurements,the mean differences of ambulatory BP were-1.943±5.475 mmHg(SBP)(P=0.923) and 3.195±5.862 mmHg(DBP)(P=0.065).All data complied with ISO 81060-2:2018 guidelines(mean ≤±5 mmHg and standard deviation ≤±8 mmHg) with no significant *** predictive values(PPV) of resting SBP and DBP were 0.635 and 0.671,*** PPV of ambulatory SBP and DBP were ***,24 h SBP circadian rhythm monitoring was performed in 107 subjects:accuracy=0.850,specificity=0.864,precision/PPV=0.833,sensitivity=0.833,and F1-measure(F1)=*** accuracy,specificity,precision,sensitivity,and F1 values in 85 subjects undergoing diurnal high SBP alerting were 0.858,0.876,0.706,0.809,and 0.754,*** When compared with the gold standard clinical sphygmomanometer,smartwatch results were cons

关键词： specificity smart dating

Investigation of natural contamination layer growth on optical substrates

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Chinese Physics C 2018年第11期42卷 107-119页

作者： Li jiang Qiu-shi Huang Igor V.Kozhevnikov yi-Yun Yao jiang-Tao Feng Yu-Fei Feng Bin Ma Hong-Fei Jiao Hong Chen Zhong Zhang Zhan-shan Wang Key Laboratory of Advanced Micro-Structured Materials MOE Institute of Precision Optical Engineering School of Physics Science and Engineering Tongji University Shanghai 200092 China Shubnikov Institute of Crystallography of Federal Scientific Research Centre "Crystallography and Photonics" of the Russian Academy of Sciences Leninskiy pr. 59 Moscow 119333 Russia

The surface contamination layer on mirrors can cause significant degradation of the optical performance, which is widely observed in applications, particularly in the fabrication of X-ray focusing telescopes. In this paper, we study the natural contamination layer arising from adsorption precipitation of hydrocarbons or other organic and water molecules in the absence of any external factor. Temporal evolution of the layer formed on super-smooth fused silica, borosilicate glass, and silicon substrates is studied by X-ray reflectometry, atomic force microscopy, and transmission electron microscopy for a one-year period after surface cleaning. The general characteristics of adhesion layer growth are established and discussed. The reconstructed dielectric constant profiles demonstrate that an increase in the adhesion layer thickness, deposited mass and density over time obeys power laws with extremely small exponents. Therefore, the adhesion layer growth is rapid immediately after surface cleaning, with a - 1 nm thick layer formed within the first day on all three substrates studied, while the layer density is low （- 1 g/cm^3）. The layer growth on the fused silica and silicon substrates became very slow in the succeeding days, with only a 1.4-1.5 nm thick layer and 1.2-1.3 g/cm^3 density after one year of storage in air. At the same time, the adhesion layer growth on the glass substrate showed unexpected acceleration about two months after cleaning, so that the layer thickness reached - 2.2 nm after one year of storage. The reason for this effect, which is connected with leaching of the glass, is discussed briefly.

关键词： X-ray telescope surface contamination surface dynamics X-ray reflectometry inverse problem

Corrosion behavior of electrodeposited Ni with normal and bimodal grain size distribution

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Transactions of Nonferrous Metals Society of China 2019年第2期29卷 424-436页

作者： Feng YANG Xiao-feng ZHANG Hong YANG yi-nong LIU shi-jie hao Li-shan CUI State Key Laboratory of Heavy Oil Processing China University of Petroleum-BeijingBeijing 102249China Beijing Key Laboratory of Failure Corrosion and Protection of Oil/Gas Facility MaterialsChina University of Petroleum-BeijingBeijing 102249China

The corrosion behavior of electrodeposited Ni with normal and bimodal grain size distribution was *** microstructure of samples was researched by SEM,EBSD,TEM and *** corrosion behavior was studied by potentiodynamic tests and electrochemical *** Ni with(100)and(111)textures was prepared by an electrodeposition *** Ni samples with different grain size distributions and twins were then obtained by heat treatment of nanocrystalline Ni at different *** effect of grain size on corrosion behavior of the sample depends on the ability of the environment to *** the case where passive film forms on the sample surface,the corrosion resistance of the sample increases with decreasing grain ***,the corrosion resistance decreases with decreasing grain size when there is no *** corrosion behavior of samples with bimodal grain size distribution obeys the rule of mixture.

关键词： corrosion behavior electrodeposited Ni bimodal grain twin grain size

Performance of the Prostate Health Index in predicting prostate biopsy outcomes among men with a negative digital rectal examination and transrectal ultrasonography

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Asian Journal of Andrology 2016年第4期18卷 633-638页

作者： Guo-Peng Yu Rong Na Ding-Wei Ye Jun Qi Fang Liu Hai-Tao Chen yi-Shuo Wu Gui-Ming Zhang Jie-Lin Sun Yao Zhu Li-Qun Huang shan-Cheng Ren De-Ke jiang S Lilly Zheng hao-Wenjiang ying-hao Sun Qiang Ding Jianfeng Xu Fudan Institute of Urology Huashan Hospital Fudan University Shanghai China Department of Urology Huashan Hospital Fudan University Shanghai China Department of Urology Fudan University Shanghai Cancer Center and Department of Oncology Shanghai Medical College Fudan University Shanghai China Department of Urology Xinhua Hospital School of Medicine Shanghai Jiao Tong University Shanghai China State Key Laboratory of Genetic Engineering School of Life Salience Fudan University Shanghai China Center for Cancer Genomics Wake Forest School of Medicine Winston-Salem North Carolina USA Department of Urology Shanghai Changhai Hospital Second Military Medical University Shanghai China Program for Personalized Cancer Care NorthShore University HealthSystem Evanston IL USA.

The [-2]proPSA （p2PSA） and its derivatives, the p2PSA-to-free PSA ratio （%p2PSA）, and the Prostate Health Index （PHI） have greatly improved discrimination between men with and without prostate cancer （PCa） in prostate biopsies. However, little is known about their performance in cases where a digital rectal examination （DRE） and transrectal ultrasonography （TRUS） are negative. A prospective cohort of 261 consecutive patients in China with negative DRE and TRUS were recruited and underwent prostate biopsies. A serum sample had collected before the biopsy was used to measure various PSA derivatives, including total prostate-specific antigen （tPSA）, free PSA, and p2PSA. For each patient, the free-to-total PSA ratio （%fPSA）, PSA density （PSAD）, p2PSA-to-free PSA ratio （%p2PSA）, and PHI were calculated. Discriminative performance was assessed using the area under the receiver operating characteristic curve （AUC） and the biopsy rate at 91% sensitivity. The AUC scores within the entire cohort with respect to age, tPSA, %fPSA, PSAD, p2PSA, %p2PSA, and PHI were 0.598, 0.751, 0.646, 0.789, 0.814, 0.808, and 0.853, respectively. PHI was the best predictor of prostate biopsy results, especially in patients with a tPSA of 10.1-20 ng ml-1. Compared with other markers, at a sensitivity of 91%, PHI was the most useful for determining which men did not need to undergo biopsy, thereby avoiding unnecessary procedures. The use of PHI could improve the accuracy of PCa detection by predicting prostate biopsy outcomes among men with a negative DRE and TRUS in China.

关键词： [-2]proPSA prostate cancer Prostate Health Index prostate-specific antigen receiver operating curve

一种新的移动Ad hoc网络的安全路由策略

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微电子学与计算机 2005年第4期22卷 30-32,37页

作者：蒋毅史浩山西北工业大学电子信息学院陕西西安710072

本文从各网络节点易受攻击、俘获,各网络节点之间不可信赖的角度出发,引入了可信任第三方的信任分散策略并结合Diffie-Hellman密钥交换算法,提出了一种新的移动Adhoc网络的安全路由策略。

关键词：移动Ad-hoc网络 CA Diffie-Hellman密钥交换算法安全路由