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Homonyms Discovery in Folksonomy Based on User Community Analysis

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Journal of Electronic Science and Technology 2016年第3期14卷 275-280页

作者： shi-Min shan yi Cui ying-hao He School of Software Dalian University of TechnologyDalian 116024China the school of management dalian university of technologyDalian 116024China

to the capability of reflecting social perception on semantic of resources, folksonomy has been proposed to improve the social learning for education and scholar researching. However, its actual impact is significantly influenced by the semantic ambiguity problem of tags. So, in this paper, we proposed a novel way of detecting homonyms, one of the main sources of tag＇s semantic ambiguity problem, in noisy folksonomies. The study is based on two hypotheses： 1） Users having different interests tend to have different understanding of the same tag. 2） Users having similar interest tend to have common understanding of the same tag. Therefore, we firstly discover user communities according to users＇ interests. Then, tag contexts are discovered in subsets of folksonomy on the basis of user communities. The experimental results show that our method is effective and outperform the method finding tag contexts using all tags in folksonomy with overlapping clustering algorithm especially when various users having different interests are contained by the folksonomyo

关键词： Community detection Folksonomy semantic ambiguity homonym.

Direct Transformation of Arenols Based on C—O Activation

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Chinese Journal of Chemistry 2020年第8期38卷 855-863页

作者： Feng Liu hao-jun jiang yi Zhou Zhang-jie shi School of Perfume and Aroma Technology Shanghai Institute of Technology100 Haiquan RdShanghai 201418China Department of Chemistry Fudan University2005 Honghu RdShanghai 200438China

Contents *** 8562.C—O Activation via the in-situ Formed Intermediate 8562.1.C—C bond formation 8562.2.C—X bond formation 8573.C—O Activation via Dearomatization-Condensation-Rearomatization Process *** catalyzed C—O cleavage of phenols,dearomatization-condensation-rearomatization process in a gas phase ***-condensation-rearomatization process in a liquid phase *** *** C—O Activation of Phenol Salts *** C—O Activation of Phenol *** and Perspective *** Transition-metal-catalyzed cross-coupling reactions of aryl electrophiles with organic or organometallic reagents emerged as one of the most powerful tools for constructing aromatic compounds.[1]In the early days,the most popular electrophiles werearyl halides because of their high reactivity and availability.

关键词： catalyzed Phenol Transformation

Evaluation of PSA-age volume score in predicting prostate cancer in Chinese population

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Asian Journal of Andrology 2018年第4期20卷 324-329页

作者： yi-Shuo Wu Xiao-Bo Wu Ning Zhang Guang-Liang jiang Yang Yu shi-Jun Tong hao-Wen jiang shan-Hua Mao Rong Na Qiang Ding Department of Urology Huashan Hospital Fudan University Shanghai 200040 China Urology Research Center Fudan University Shanghai 200040 China Department of Urology Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200025 China

This study was performed to evaluate prostate-specific antigen-age volume （PSA-AV） scores in predicting prostate cancer （PCa） in a Chinese biopsy population. A total of 2355 men who underwent initial prostate biopsy from January 2006 to November 2015 in Huashan Hospital were recruited in the current study. The PSA-AV scores were calculated and assessed together with PSA and PSA density （PSAD） retrospectively. Among 2133 patients included in the analysis, 947 （44.4%） were diagnosed with PCa. The mean age, PSA, and positive rates of digital rectal examination result and transrectal ultrasound result were statistically higher in men diagnosed with PCa （all P 〈 0.05）. The values of area under the receiver operating characteristic curves （AUCs） of PSAD and PSA-AV were 0.864 and 0.851, respectively, in predicting PCa in the entire population, both performed better than PSA （AUC = 0.805; P 〈 0.05）. The superiority of PSAD and PSA-AV was more obvious in subgroup with PSA ranging from 2.0 ng ml^-1 to 20.0 ng ml^-1. A PSA-AV score of 400 had a sensitivity and specificity of 93.7% and 40.0%, respectively. In conclusion, the PSA-AV score performed equally with PSAD and was better than PSA in predicting PCa. This indicated that PSA-AV score could be a useful tool for predicting PCa in Chinese population.

关键词： age China prostate cancer prostate-specific antigen volume

Tuning composite solid-state electrolyte interface to improve the electrochemical performance of lithium-oxygen battery

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Green Energy & Environment 2023年第4期8卷 1195-1204页

作者： hao Ouyang shan Min Jin yi Xiaoyu Liu Fanghua Ning Jiaqian Qin Yong jiang Bing Zhao Jiujun Zhang School of Environmental and Chemical Engineering Shanghai UniversityShanghai200444China Institute for Sustainable Energy/College of Sciences Shanghai UniversityShanghai200444China Center of Excellence in Responsive Wearable Materials Metallurgy and Materials Science Research InstituteChulalongkorn UniversityBangkok10330Thailand

Thin and flexible composite solid-state electrolyte(SSE) is considered to be a prospective candidate for lithium-oxygen(Li-O_(2)) batteries with the aim to address the problems of unsatisfied safety, terrible durability as well as inferior electrochemical performance. Herein, in order to improve the safety and durability, a succinonitrile(SN) modified composite SSE is proposed. In this SSE, SN is introduced for eliminating the boundary between ceramic particles, increasing the amorphous region of polymer and ensuring fast ionic transport. Subsequently, the symmetric battery based on the proposed SSE achieves a long cycle life of 3000 h. Moreover, the elaborate cathode interface through the SN participation effectively reduces the barriers to the combination between lithium ions and electrons, facilitating the corresponding electrochemical *** a result, the solid-state Li-O_(2)battery based on this SSE and tuned cathode interface achieves improved electrochemical performance including large specific capacity over 12,000 m Ah g^(-1), enhanced rate capacity as well as stable cycle life of 54 cycles at room temperature. This ingenious design provides a new orientation for the evolution of solid-state Li-O_(2)batteries.

关键词： Solid-state Li-O_(2)battery Composite electrolyte Cathode interface Room temperature Succinonitrile

Revolutionizing stem cell research:unbiased insights through single-cell sequencing

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BIOCELL 2024年第11期48卷 1531-1542页

作者： hao WU NA HUO SITUO WANG ZIWEI LIU yi jiang QUAN shi Institute of Stomatology First Medical CenterChinese PLA General HospitalBeijing100853China

Stem cells have shown great application potential in wound repair,tissue regeneration,and disease ***,a full understanding of stem cells and their related regulatory mechanisms in disease treatment is conducive to improving the therapeutic effect of stem ***,thus far,there are still many unsolved mysteries in theﬁeld of stem cells due to technical limitations,which hinder the in-depth exploration of stem cells and their wide clinical ***-cell sequencing(SCS)has provided very powerful and unbiased insights into cell gene expression proﬁles at the single-cell level,bringing exciting results to the stem cellﬁ*** present,SCS has been widely applied in theﬁeld of stem cells,covering various aspects,including lineage tracing the development of stem cells,identifying new stem cell types,exploring cellular heterogeneity,and identifying internal functional *** this paper,we focus on the latest research progress and discuss the application of SCS technology in stem cells.

关键词： Stem cell Single-cell sequencing Cellular heterogeneity Subpopulations Functional analysis Lineage-tracing

Rietveld refinement,microstructure,mechanical properties and oxidation characteristics of Fe-28Mn-xAl-1C(x=10 and 12 wt.%)low-density steels

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Journal of Iron and Steel Research International 2017年第12期24卷 1190-1198页

作者： Zhen-yi Huang A-long Hou Yue-shan jiang Ping Wang Qi shi Qing-yu Hou Xiang-hua Liu School of Metallurgical Engineering Anhui University of TechnologyMa'anshan 243002AnhuiChina Key Laboratory of Metallurgical Emission Reduction&Resources Recycling Ministry of EducationAnhui University of TechnologyMaranshan 243002AnhuiChina Industrial&Commercial College Anhui University of TechnologyMa'anshan 243002AnhuiChina State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110819LiaoningChina

The quantitative relationship between microstructure and properties of austenitic Fe-28Mn-xAl-1C（x=10 and 12 wt.%）low-density steels was evaluated using Rietveld method to refine X-ray diffraction（XRD）*** results showed that a typical three-phase austenitic steel was obtained in the forged Mn28Al10（***-28Mn-10Al-1C）steel,which included about 92.85 wt.% γ-Fe（Mn,Al,C）（austenite）,5.28 wt.%（Fe,Mn）_3AlC_（0.5）（κ-carbide）,and 1.87 wt.% α-Fe（Al,Mn）（ferrite）.For the forged Mn28Al12（***-28Mn-12Al-1C）steel,nevertheless,only about 76.64 wt.% austenite,9.63 wt.%κ-carbide,9.14 wt.%ferrite and 4.59 wt.% Fe_3Al（DO_3）could be ***κ-carbide and DO_3 were mainly distributed in austenite grains and at the interface between austenite and ferrite,*** forged Mn28Al10 steel had a better combination of strength,ductility and specific strength as compared with the forged Mn28Al12 *** ductility of the forged Mn28Al12 steel was far lower than that of the forged Mn28Al10 *** oxidation kinetics of Mn28Al10 steel oxidized at 1323 Kfor 5-25 h had two-stage linear rate laws,and the oxidation rate of the second stage was faster than that of the first *** the oxidation kinetics of Mn28Al12 steel under this condition also had two-stage linear rate laws,the oxidation rate of the second stage was slower than that of the first *** the oxidation temperature increased to 1373K,the oxidation kinetics of the two steels at 5-25 hhad only onestage linear rate law,and the oxidation rates of the two steels were far faster than those at 1323K for5-25 *** oxidation resistance of Mn28Al12 steel was much better than that of Mn28Al10 *** layer formed between the austenite matrix and the oxidation layer of the two Fe-Mn-Al-C steels oxidized at high temperature.

关键词： Low-density steel Rietveld method Microstructure Mechanical property Oxidation characteristics

Interactions of acetylcholinesterase with salvianolic acid B and rosmarinic acid from Salvia miltiorhiza water extract investigated by NMR relaxation rate

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Chinese Chemical Letters 2008年第6期19卷 747-751页

作者： GuoWei yin yi Ming Li Wei Wei shan hao jiang Da Yuan Zhu Wei Hong Du Department of Chemistry Renmin University of China 59 Zhong Guan Cun Street Beijing 100872 China School of Pharmacy Shanghai University of Traditional Chinese Medicine 1200 Cailun Road Shanghai 201203 China State Key Laboratory for Drug Research Shanghai Institute of Materia Medica Shanghai Institutes for Biological Sciences Chinese Academy of Sciences 555 Zuchongzhi Road Shanghai 201203 China

In order to understand whether the ameliorating effect on old ages memory disorder by the root of Salvia miltiorhiza is related to the acetylcholinesterase （ACHE） inhibition, two main ingredients, salvianolic acid B （1） and rosmarinic acid （2）, which were isolated from S. miltiorhiza water extract, were investigated in vitro by NMR relaxation rate in this work. The results showed that the proton selective relaxation rates and the molecular rotational correlation time of proton pairs for compounds 1 and 2 increased significantly by adding of AChE in mixing solution. The study reveals that the two compounds might bind to the enzyme and have ACHE inhibitory effect, which could contribute to the ameliorating effect at some extent on old ages memory disorder.

关键词： AChE inhibitors Salvianolic acid B Rosmarinic acid NMR relaxation rate

MonkeyTrail:A scalable video-based method for tracking macaque movement trajectory in daily living cages

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Zoological Research 2022年第3期43卷 343-351页

作者： Meng-shi Liu Jin-Quan Gao Gu-Yue Hu Guang-Fu hao Tian-Zi jiang Chen Zhang shan Yu Brainnetome Center Institute of AutomationChinese Academy of SciencesBeijing 100190China National Laboratory of Pattern Recognition Institute of AutomationChinese Academy of SciencesBeijing 100190China School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 101408China Technology Management Center SAFE Pharmaceutical Technology Co.Ltd.Beijing 100176China Model R&D Center Beijing Life Biosciences Co.Ltd.Beijing 100176China Key Laboratory for NeuroInformation of Ministry of Education School of Life Science and TechnologyUniversity of Electronic Science and Technology of ChinaChengduSichuan 611731China Department of Neurobiology School of Basic Medical SciencesBeijing Key Laboratory of Neural Regeneration and Repairand Advanced Innovation Center for Human Brain ProtectionCapital Medical UniversityBeijing 100069China Current address:School of Computing National University of SingaporeSingapore 119077Singapore

Behavioral analysis of macaques provides important experimental evidence in the field of *** recent years,video-based automatic animal behavior analysis has received widespread ***,methods capable of extracting and analyzing daily movement trajectories of macaques in their daily living cages remain underdeveloped,with previous approaches usually requiring specific environments to reduce interference from occlusion or environmental ***,we introduce a novel method,called MonkeyTrail,which satisfies the above requirements by frequently generating virtual empty backgrounds and using background subtraction to accurately obtain the foreground of moving *** empty background is generated by combining the frame difference method(FDM)and deep learning-based model(YOLOv5).The entire setup can be operated with low-cost hardware and can be applied to the daily living environments of individually caged *** test MonkeyTrail performance,we labeled a dataset containing>8000 video frames with the bounding boxes of macaques under various conditions as *** showed that the tracking accuracy and stability of MonkeyTrail exceeded that of two deep learningbased methods(YOLOv5 and Single-Shot MultiBox Detector),traditional frame difference method,and na?ve background subtraction *** MonkeyTrail to analyze long-term surveillance video recordings,we successfully assessed changes in animal behavior in terms of movement amount and spatial ***,these findings demonstrate that MonkeyTrail enables low-cost,large-scale daily behavioral analysis of macaques.

关键词： Movement trajectory tracking Video-based behavioral analyses Background subtraction Virtual empty background Occlusion

Intermittent Theta Burst Stimulation Attenuates Cognitive Deficits and Alzheimer’s Disease-Type Pathologies via ISCA1-Mediated Mitochondrial Modulation in APP/PS1 Mice

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Neuroscience Bulletin 2024年第2期40卷 182-200页

作者： Yang Zhu hao Huang Zhi Chen Yong Tao Ling-yi Liao shi-hao Gao Yan-jiang Wang Chang-Yue Gao Department of Rehabilitation Medicine Daping HospitalArmy Medical UniversityChongqing 400042China Department of Neurology and Center for Clinical Neuroscience Daping HospitalArmy Medical UniversityChongqing 400042China Department of Special Medicine Daping HospitalArmy Medical UniversityChongqing 400042China

Intermittent theta burst stimulation(iTBS),a time-saving and cost-effective repetitive transcranial magnetic stimulation regime,has been shown to improve cognition in patients with Alzheimer’s disease(AD).However,the specific mechanism underlying iTBS-induced cognitive enhancement remains *** studies suggested that mitochondrial functions are modulated by magnetic ***,we showed that iTBS upregulates the expression of iron-sulfur cluster assembly 1(ISCA1,an essential regulatory factor for mitochondrial respiration)in the brain of APP/PS1 *** vivo and in vitro studies revealed that iTBS modulates mitochondrial iron-sulfur cluster assembly to facilitate mitochondrial respiration and function,which is required for ***,iTBS rescues cognitive decline and attenuates AD-type pathologies in APP/PS1 *** present study uncovers a novel mechanism by which iTBS modulates mitochondrial respiration and function via ISCA1-mediated iron-sulfur cluster assembly to alleviate cognitive impairments and pathologies in *** provide the mechanistic target of iTBS that warrants its therapeutic potential for AD patients.

关键词： Intermittent theta burst stimulation Alzheimer’s disease Iron-sulfur cluster assembly 1 Mitochondrial dysfunction Neurodegeneration