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Risk factors and prognostic value of acute severe lower gastrointestinal bleeding in Crohn’s disease

World Journal of Gastroenterology 2021年第19期27卷 2353-2365页

作者： Jiyoung Yoon Dae Sung kim ye-jee kim Jin Wook Lee Seung Wook Hong Ha Won Hwang Sung Wook Hwang Sang Hyoung Park Dong-Hoon Yang Byong Duk ye Jeong-Sik Byeon Seung-Jae Myung Suk-Kyun Yang Department of Gastroenterology Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea Department of Clinical Epidemiology and Biostatistics Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea

BACKGROUND Acute severe lower gastrointestinal bleeding(LGIB)is an uncommon but challenging complication of Crohn’s disease(CD).AIM To identify the predictors of acute severe LGIB and to evaluate the impact of acute severe LGIB on the subsequent clinical course in CD *** A retrospective inception cohort study was conducted in 75 CD patients with acute severe LGIB and 1359 CD patients without acute severe LGIB who were diagnosed between February 1991 and November 2019 at Asan Medical Center,a tertiary university hospital in *** analysis with Cox proportional hazard regression was performed to identify the risk factors for acute severe LGIB.A matched analysis using 72 patients with bleeding and 267 matched patients without within the cohort was also conducted to investigate whether acute severe LGIB is a predictor of clinical outcomes of *** Multivariable Cox regression analysis revealed that early use of thiopurines[hazard ratio(HR):0.23,95%confidence interval(CI):0.12-0.48;Pyears;P=0.012).However,if hospitalizations due to bleeding episodes were excluded from the analysis,the hospitalization rate was not significantly different between the bleeding group and the matched nonbleeding group(14.5/100 vs 13.2/100 patient-years;P=0.631).CONCLUSION Early use of thiopurines may reduce the risk of acute severe *** of acute severe LGIB may not have a significant prognostic value in patients with CD.

关键词： Gastrointestinal hemorrhage Lower gastrointestinal tract Crohn’s disease Risk factors Cohort studies Clinical course

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Mechanical characteristics of fused cast basalt tube encased in steel pipe for protecting steel surface

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中国有色金属学会会刊：英文版 2009年第4期19卷 935-940页

作者： jee-Seok WANG Jong-Do kim Hee-Jong YOON Division of Mechanical and Information Engineering Korea Maritime University Division of Marine System Engineering Korea Maritime University Department of Research and Development Dongdo Basalt Industry Co.Ltd

Because of the various excellent characteristics of cast basalt materials,such as,anti-corrosion,anti-wearing,good hardness,high chemical stability,of which steel may not possess,the steel-basalt composite pipes are used in severe environments for compensating the defects of *** limit of bending moment with which steel-basalt composite pipe may safely endure was calculated and the limit curvature of the composite pipe in the safe range was *** application temperature of steel-basalt pipe was examined due to a different coefficient among basalt,mortar and mild steel.

关键词：玄武岩钢管表面保护机械特性包裹熔铸化学稳定性复合管

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Single-atom Pd catalyst anchored on Zr-based metal-organic polyhedra for Suzuki-Miyaura cross coupling reactions in aqueous media

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Nano Research 2021年第2期14卷 486-492页

作者： Seongsoo kim Seohyeon jee Kyung Min Choi Dong-Sik Shin Division of Chemical and Bioengineering Kangwon National UniversityGangwon-do 24341Republic of Korea Department of Chemical and Biological Engineering Sookmyung Womens University100 Cheongpa-ro 47-gilYongsan-guSeoul 04310Republic of Korea

The challenge for single-atom catalysts in various C-C cross coupling reaction exists in the development of solid supporting *** has been desired tofind a supporting material designed in molecular level to anchor a single-atom catalyst and provide high degree of dispersion and substrate access in aqueous ***,we prepared discrete cages of metal-organic polyhedra anchoring single Pd atom(MOP-BPY(Pd))and successfully performed a Suzuki-Miyaura cross coupling reaction with various substrates in aqueous *** was revealed that each tetrahedral cage of MOP-BPY(Pd)has 4.5 Pd atoms on average and retained its high degree of dispersion up to 3 months in *** coupling efficiencies of the Suzuki-Miyaura cross coupling reaction exhibited more than 90.0%for various substrates we have tested in the aqueous media,which is superior to those of the molecular Pd complex and metal-organic framework(MOF)anchoring Pd ***,MOP-BPY(Pd)was successfully recovered and recycled without performance degradation.

关键词： metal-organic polyhedra Suzuki-Miyaura cross coupling reaction structure characterization aqueous phase reaction high-degree of dispersion

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Optimal design of auxiliary-teeth to solve circulation current reduction of permanent magnet linear synchronous motor

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Journal of Central South University 2011年第3期18卷 690-696页

作者： JANG Ki-bong kim jee-hyun AN Ho-jin kim Gyu-tak School of Mechatronics Changwon National University

A discontinuity of magnetic circuits according to the end effect is generated in the permanent magnet linear synchronous motor （PMLSM）. Due to the unbalanced back electro-motive force （EMF） and impedance produced, unbalanced current is generated. The cireulatin8 current, which is caused by a decrease in the thrust, is generated by the unbalanced current. The optimal design of auxiliary-teeth at the end of the mover was carried out to solve the unbalance of phase by using design of experiment （DOE）, and compared with the basic model through finite element analysis （FEA）. As a result, the auxiliary-teeth model compensates for the decrease of thrust caused by the unbalanced phase. Also, this model is proven to reduce the detent force by the vibration and noise of the PMLSM and copper loss caused by the circulating current.

关键词： permanent magnet linear synchronous motor auxiliary-teeth circulation current end effect thrust reduction

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Counter-balancing effects of Si on C partitioning and stacking fault energy of austenite in 10Mn quenching and partitioning steel

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Journal of Materials Science & Technology 2022年第3期98卷 248-257页

作者： Dong Hwi kim jee-Hyun Kang Hojun Gwon Joo Hyun Ryu Sung-Joon kim Graduate Institute for Ferrous Technology Pohang University of Science and TechnologyPohang 37673Republic of Korea School of Materials Science and Engineering Institute of Materials TechnologyYeungnam UniversityGyeongsan 38541Republic of Korea POSCO Technical Research Laboratories POSCOGwangyang 57807Republic of Korea

Silicon is an essential alloying element in quenching and partitioning(Q&P)steels,because it is known to suppress carbide precipitation during partitioning step and promote carbon partitioning to stabilize *** 2 wt%Si was added to 10Mn-2Al-0.2C steel,the size and fraction of the carbides formed during partitioning became smaller than in the Si-free ***,the suppression of carbide formation promoted C partitioning into austenite as ***,austenite stability was always lower with Si under the equivalent partitioning condition because Si effectively decreased the stacking fault energy of *** partitioning progressed,the both yield and tensile strengths of the Si-added steel exceeded that of the Si-free steel with the similar ductility *** was because Si was an effective solid solution strengthener,and the austenite in the Si-added steel exhibited the appropriate stability to gradually transform into martensite throughout the *** resulting strengthening effect compensated for the softening caused by martensite ***,strain hardening rate decreased continuously throughout deformation,which resulted in high tensile strength and ductility.

关键词： Steels Q&P steel Silicon Austenite stability Tensile deformation Stacking fault energy Medium Mn steel

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Imidazole linker‐induced covalent triazine framework-ZIF hybrids for confined hollow carbon super‐heterostructures toward a long‐life supercapacitor

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Carbon Energy 2023年第10期5卷 25-39页

作者： Madagonda MVadiyar Ji‐Young kim jee‐Hwan Bae Kyung‐Wan Nam Department of Energy and Materials Engineering Dongguk UniversitySeoulSouth Korea Advanced Analysis&Data Center Korea Institute of Science and Technology(KIST)SeoulSouth Korea Advanced Energy and Electronic Materials Research Center Dongguk UniversitySeoulSouth Korea

Carbon super-heterostructures with high nitrogen contents from the covalent hybrid precursors of covalent triazine frameworks(CTFs)and zeolitic imidazolic frameworks(ZIFs)are scarcely explored because of CTF's ordered structure and toxic superacid that dissolves or destabilizes the metal *** solve this problem,herein,we report a straightforward two-step pathway for the covalent hybridization of disordered CTF(d–CTF)–ZIF composites via preincorporation of an imidazole(IM)linker into ordered CTFs,followed by the imidazole-site-specific covalent growth of *** carbonization of these synthesized d–CTF−IM−ZIF hybrids results in unique hollow carbon super-heterostructures with ultrahigh nitrogen content(>18.6%),high specific surface area(1663m^(2)g^(−1)),and beneficial trace metal(Co/Zn NPs)contents for promoting the redox *** proof of concept,the obtained carbon super-heterostructure(Co–Zn–NC_(SNH)–800)is used as a positive electrode in an asymmetric supercapacitor,demonstrating a remarkable energy density of 61Wh kg^(−1)and extraordinary cyclic stability of 97%retention after 30,000 cycles at the cell *** presynthetic modifications of CTF and their covalent hybridization with ZIF crystals pave the way toward new design strategies for synthesizing functional porous carbon materials for promising energy applications.

关键词： asymmetric supercapacitor defective covalent triazine frameworks hollow carbon superheterostructures linker defect

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Detecting IoT Botnet in 5G Core Network Using Machine Learning

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Computers, Materials & Continua 2022年第9期72卷 4467-4488页

作者： ye-Eun kim Min-Gyu kim Hwankuk kim Department of Electronics Information and System Engineering Sangmyung UniversityCheonan-siKorea Department of Information Security Engineering Sangmyung UniversityCheonan-siKorea

As Internet of Things(IoT)devices with security issues are connected to 5G mobile networks,the importance of IoT Botnet detection research in mobile network environments is ***,the existing research focused on AI-based IoT Botnet detection research in wired network *** addition,the existing research related to IoT Botnet detection in ML-based mobile network environments have been conducted up to ***,this paper conducts a study on ML-based IoT Botnet traffic detection in the 5G core *** binary and multiclass classification was performed to compare simple normal/malicious detection and normal/threetype IoT Botnet malware *** both classification methods,the IoT Botnet detection performance using only 5GC’s GTP-U packets decreased by at least 22.99%of accuracy compared to detection in wired network *** addition,by conducting a feature importance experiment,the importance of feature study for IoT Botnet detection considering 5GC network characteristics was *** this paper analyzed IoT botnet traffic passing through the 5GC network using ML and presented detection results,think it will be meaningful as a reference for research to link AI-based security to the 5GC network.

关键词： IoT botnet 5G B5G malware machine learning

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Acceleration of aging behavior and improvement of mechanical properties of extruded AZ80 alloy through(10–12) twinning

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Journal of Magnesium and Alloys 2023年第2期11卷 671-683页

作者： Hyun Ji kim ye Jin kim Sung Hyuk Park School of Materials Science and Engineering Kyungpook National UniversityDaegu 41566Republic of Korea

The effects of pre-existing {10–12} extension twins on the precipitation behavior of an extruded AZ80 material during aging and on its mechanical properties after peak aging are investigated. The material containing {10–12} twins-which are formed by compression before aging(twinned material)-has a finer grain size and higher dislocation density than the extruded material. Although the peak hardnesses of the twinned and extruded materials are almost the same, the time to reach the peak hardness is considerably shorter in the former material than in the latter(4 h and 24 h, respectively). In the twinned material, the high dislocation density of the {10–12} twins promotes continuous precipitation, which results in the formation of numerous fine Mg17Al12precipitates within the twins in the early stage of *** formation of these continuous precipitates reduces the driving force for discontinuous precipitation, which consequently suppresses the formation and growth of coarse Mg17Al12precipitates at the grain boundaries. Despite its shorter peak-aging time, the 4 h-peak-aged twinned material shows higher tensile strength and elongation than the 24 h-peak-aged extruded material. These higher mechanical properties of the former material are attributed primarily to the presence of more abundant fine continuous precipitates, which are effective in strengthening the material, and less abundant coarse discontinuous precipitates, which can act as crack initiation sites. These results demonstrate that the introduction of {10–12} twins into wrought Mg–Al-based alloys can accelerate the Mg17Al12precipitation kinetics considerably and improve the strength and ductility of the peak-aged alloys simultaneously.

关键词： AZ80 alloy Twin Aging Precipitation Tensile properties

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Obesity and novel management of inflammatory bowel disease

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World Journal of Gastroenterology 2023年第12期29卷 1779-1794页

作者： jee Hyun kim Chang-Myung Oh Jun Hwan Yoo Department of Gastroenterology CHA Bundang Medical CenterCHA University School of MedicineSeongnam 13496South Korea Department of Biomedical Science and Engineering Gwangju Institute of Science and TechnologyGwangju 62465South Korea Institute of Basic Medical Sciences CHA University School of MedicineSeongnam 13496South Korea

Obesity is prevalent within the inflammatory bowel disease(IBD)population,particularly in newly developed *** epidemiological studies have suggested that 15%-40%of IBD patients are obese,and there is a potential role of obesity in the pathogenesis of *** dysfunction of mesenteric fat worsens the inflammatory course of Crohn’s disease and may induce formation of strictures or ***,obesity may affect the disease course or treatment response of *** the increasing data supporting the pathophysiologic and epidemiologic relationship between obesity and IBD,obesity control is being suggested as a novel management for ***,this review aimed to describe the influence of obesity on the outcomes of IBD treatment and to present the current status of pharmacologic or surgical anti-obesity treatments in IBD patients.

关键词： Obesity Inflammatory bowel disease Crohn’s disease Ulcerative colitis

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Uncontrolled high blood pressure under total intravenous anesthesia with propofol and remifentanil:A case report

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World Journal of Clinical Cases 2022年第26期10卷 9411-9416页

作者： Min Jung Jang jee Hee kim Hae Jeong Jeong Anesthesiology and Pain Medicine National Cancer CenterGoyang 10408South Korea

BACKGROUND Although propofol generally reduces blood pressure,rarely,it causes ***,the mechanism by which propofol increases blood pressure has not been established,and so far,there are only a few reported *** SUMMARY A 46-year-old woman,diagnosed with thyroid cancer,was administered general anesthesia with propofol and remifentanil for a thyroid *** increase in the concentrations of intravenous anesthetics further increased her blood *** blood pressure remained stable when anesthesia was maintained with sevoflurane and remifentanil after the interruption of propofol *** We concluded that propofol administration was the cause of increased blood pressure.

关键词： Anesthesia Intravenous Hypertension Propofol Remifentanil Tachycardia Case report

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