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目的评价雷公藤多苷联合糖皮质激素治疗免疫球蛋白A(Ig A)肾病的临床疗效和安全性。方法 120例Ig A肾病患者随机分为试验组58例和对照组62例,对照组口服醋酸泼尼松片0.5 mg·kg-1,qd和氯沙坦钾50 mg·d-1,qd,试验组在对照组的基础上口服雷公藤多苷片1 mg·kg-1,tid,2组患者疗程均为3个月。观察2组的临床疗效、肾功能指标及不良反应发生率。结果试验组和对照组总有效率分别为89.7%和74.2%,试验组显著高于对照组(P0.05)。结论雷公藤多苷联合糖皮质激素治疗Ig A肾病较单用糖皮质激素疗效更为明显,且不增加不良反应发生率。

关键词：雷公藤多苷糖皮质激素免疫球蛋白A肾病不良反应

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Differences of Band Gap Characteristics of Square and Triangular Lattice Photonic Crystals in Terahertz Range

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Journal of Electronic Science and Technology of China 2009年第3期7卷 268-271页

作者： Jie Zha Zhi-Yong Zhong Huai-Wu Zhang Qi-ye Wen Yuan-xun Li School of Microelectronics and Solid-State Electronics University of Electronic Science and Technology of China Chengdu 610054 China

Band gap characteristics of the photonic crystals in terahertz range with square lattice and triangular lattice of GaAs cylinders are comparatively studied by means of plane wave method （PWM）. The influence of the radius on the band gap width is analyzed and the critical values where the band gap appears are put forward. The results show that the maximum band gap width of photonic crystal with triangular lattice of GaAs cylinders is much wider than that of photonic crystal with square lattice. The research provides a theoretic basis for the development of terahertz （THz） devices.

关键词： Band gap structure critical value expansion method photonic crystals plane wave GaAs terahertz waves

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Postoperative hemorrhage during the acute phase after direct or combined revascularization for moyamoya disease: risk factors, prognosis and literature review

Postoperative hemorrhage during the acute phase after direct...

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第十四届中国医师协会神经外科医师年会

作者： Yu Chen Li Ma Junlin Lu Xiaolin Chen xun ye Rong Wang Yuanli Zhao Department of Neurosurgery Beijing Tiantan HospitalCapital Medical University

Postoperative hemorrhage during the acute phase is rarely observed after the revascularization surgery for moyamoya disease（MMD） but have severe complications. Its risk factors and outcomes are still unclear. The aim of this study was to investigate the predictors of postoperative hemorrhage during the acute phase in MMD and examine the outcomes of the hemorrhage. Methods: The authors reviewed the preoperative clinical characteristics and radiographic features of 465 consecutive MMD cases（518 procedures） who underwent direct or combined bypass surgery in our institution between 2009 and 2015. Patients with postoperative intracerebral hemorrhage（ICH） or ICH + intraventricular hemorrhage（IVH） during the acute phase were screened, then the incidence, hemorrhage locations and risk factors of these patients were analyzed. Short-term and long-term outcomes（modified Rankin Scale [mRS]） for these patients were also collected. Outcomes were compared between patients who had postoperative ICH and those without postoperative ICH, using propensity-score analysis to reduce the between-group differences in the baseline characteristics. Results: Postoperative hemorrhage occurred in 11 cases from the 518 procedures（2.1%;mean age, 39.82±8.8 years;ICH=9, IVH=2）. 8 cases（72.7%） occurred hemorrhage in the first 24 hours after the operation. In the ICH group, most of the hemorrhage sites（77.8%） were located beneath the anastomosed area, and the mean hematoma volume was 16.98±22.45 ml（range 3-57 ml）. 1 case from the ICH group required hematoma evacuation. For the adult patients（463 procedures, 89.4%）, preoperative hypertension（P=0.005）, computed tomography perfusion（CTP） stage＞Ⅲ（P=0.043） and posterior circulation involvement（P=0.027） were significantly associated with postoperative ICH. No significant differences were detected between the postoperative ICH group and the no-hemorrhage group in postoperative neurofunctional status at discharge（P=0.569） and at the last follow-up（P=1.000）. T

关键词： Moyamoya disease Postoperative hemorrhage Cerebral hyperperfusion syndrome Direct revascularization

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Study on DNA Cytosine Methylation of Cotton (Gossypium hirsutum L.) Genome and Its Implication for Salt Tolerance

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Agricultural Sciences in China 2010年第6期9卷 783-791页

作者： ZHAO Yun-lei,YU Shu-xun,ye Wu-wei,WANG Hong-mei,WANG Jun-juan and FANG Bao-xing Cotton Research Institute,Chinese Academy of Agricultural Sciences (CAAS)/Key Laboratory of Cotton Genetic Improvement,Ministry of Agriculture,Anyang 455000,P.R.China Cotton Research Institute Chinese Academy of Agricultural Sciences (CAAS)/Key Laboratory of Cotton Genetic Improvement Ministry of Agriculture Anyang 455000 P.R.China

To study the relations between DNA methylation and abiotic stress responses in cotton （Gossypium hirsutum L.）,the methylation-sensitive amplified polymorphism （MSAP） method was used to investigate the differences in methylation level and the change of cytosine methylation patterns under salt （NaCl） stress in two different salt-tolerant cotton *** results showed that the number of the cytosine methylation of CCGG sites in high salt-tolerant cotton line was less than that in low salt-tolerant *** salt stress,extensive cytosine methylation alterations including hypermethylation and demethylation as well as the potential conversion of methylation types occurred in the salt-treated cotton line compared with the corresponding ***,salt stress-induced demethylation loci that occurred in high salt- tolerant cotton line were greater than those in low salt-tolerant cotton line,however,salt stress-induced hypermethylation loci in the high salt-tolerant cotton line were less than those in low salttolerant cotton *** suggested that the demethylation positively contributed to salt tolerance and the hypermethylation had negative effect on salt tolerance in cotton.

关键词： cotton DNA methylation salt stress MSAP methylation polymorphism

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维普期刊数据库

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Cerebral ischemia at early postoperative period of direct revascularization for moyamoya disease: a case report and literature review

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Neuroimmunology and Neuroinflammation 2017年第3期4卷 46-53页

作者： Xiao-Lin Chen Li Ma Yu Chen Jun-Lin Lu xun ye Rong Wang Yuan-Li Zhao Department of Neurosurgery Beijing Tiantan HospitalCapital Medical UniversityBeijing100050China China National Clinical Research Center for Neurological Diseases Beijing100050China Department of Neurosurgery Peking University International HospitalPeking University Health Science CenterBeijing102206China Center of Stroke Beijing Institute for Brain DisordersBeijing100050China Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease Beijing100050China

Hypoperfusion and hyperperfusion could be causes of early postoperative complications that lead to neurological deterioration in patients with moyamoya diseases (MMD) after superficial temporal artery (STA) and middle cerebral artery (MCA) anastomosis. Here, the authors described a case of child-onset bilateral MMD that manifested transient cerebral ischemia in the contralateral hemisphere after left STA-MCA bypass in young adulthood. A new onset of cerebral ischemia in the contralateral hemisphere and transient neurological deterioration suggested the fragile hemodynamics of MMD during early perioperative period. Serial evaluation of postoperative cerebral hemodynamics and perfusion might facilitate targeted management in patients with unstable or advanced MMD.

关键词： Moyamoya disease cerebral revascularization transient neurological events perioperative management

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突发公共卫生事件社会共治路径构建--以公私权力冲突为视角

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北京行政学院学报 2020年第3期 37-45页

作者：胡业勋王彦博中共四川省委党校法学教研部四川成都610000

新型冠状病毒肺炎疫情诱发的社会风险对国家治理现代化提出了全新挑战,社会共治作为公私权力合理配置下的多元主体共同治理方式,是防控突发公共卫生事件的重要方式。在突发公共卫生事件中,权力性质差异、外界状态刺激、特殊场域加剧等... 详细信息

新型冠状病毒肺炎疫情诱发的社会风险对国家治理现代化提出了全新挑战,社会共治作为公私权力合理配置下的多元主体共同治理方式,是防控突发公共卫生事件的重要方式。在突发公共卫生事件中,权力性质差异、外界状态刺激、特殊场域加剧等诸多因素共同作用,致使权力平衡被打破,进而呈现出公权力异化、私权力无序以及衔接错位等多种权力冲突的现实样态。构筑突发事件中社会共治的路径,需立足于权力冲突的内在机理,着眼于权力平衡要素,从机理更新、模式创新、结构延展以及导向过渡四个维度加以探索。

关键词：社会共治突发公共卫生事件权力平衡

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