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Empirical Changes in the Prevalence of Overweight and Obesity among Chinese Students from 1985 to 2010 and Corresponding Preventive Strategies

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Biomedical and Environmental Sciences 2013年第1期26卷 1-12页

作者： JI cheng ye CHEN Tian Jiao Working Group on Obesity in China (WGOC) Institute of Child and Adolescent Health School of Public Health Peking University Health Science CenterBeijing 100191 China Institute of Child and Adolescent Health School of Public Health Peking UniversityHealth Science Center Beijing 100191 China' 3. WGOC.' Working Group on Obesity in China International LifeSciences Institute Focal Point in China WGOC: Working Group on Obesity in China International LifeSciences Institute Focal Point in China

Objective To determine the extent of the obesity epidemic in school‐aged Chinese children in 2010 and track the increasing trend in different socioeconomic regions over the preceding 25 years. Strategies for preventing childhood obesity are suggested. Methods We used a dataset provided by the Chinese National Survey on Students’ Constitution and Health from 1985‐2010. Subjects were 7‐18‐year‐old students randomly selected from urban and rural areas in 30 provinces. Eight subgroups were created according to region and socioeconomic status. Results Increased rates of the epidemic （overweight and obesity combined） were greatest in large coastal cities‐32.6% and 19.1% among males and females, respectively. These rates has neared that of developed countries. Similar increases were found in all other regions, including the once poverty‐stricken rural west. The epidemic in most of the rural areas began after 2000, but has spread swiftly over the last decade. In 2010, it was estimated that 9.9% of Chinese school‐aged children and adolescents were overweight and that an additional 5.1% were obese, representing an estimated 30.43 million individuals. Conclusion The prognosis for China＇s childhood‐obesity epidemic is dire. To prevent childhood obesity, we suggest several strategies, including reasonable dietary intake, increase physical activity, a change in sedentary lifestyles and corresponding behavioral modifications.

关键词： Obesity Chinese school‐aged children Prevalence Temporal changes Socioeconomic status

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Using Lyapunov function to design optimal controller for AQM routers

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第1期8卷 113-118页

作者： ZHANG Peng ye cheng-qing MA Xue-ying CHEN Yan-hua LI Xin School of Computer Science and Technology Zhejiang University Hangzhou 310027 China

It was shown that active queue management schemes implemented in the routers of communication networks sup-porting transmission control protocol (TCP) flows can be modelled as a feedback control system. In this paper based on Lyapunov function we developed an optimal controller to improve active queue management (AQM) router’s stability and response time, which are often in conflict with each other in system performance. Ns-2 simulations showed that optimal controller outperforms PI controller significantly.

关键词： TCP flows Active queue management (AQM) Lyapunov function Optimal controls

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Late Miocene wood flora associated with the Yuanmou hominoid fauna from Yunnan, southwestern China and its palaeoenvironmental implication

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Journal of Palaeogeography 2014年第3期3卷 323-330页

作者： ye-Ming cheng Yu-Fei Wang cheng-Sen Li The Geological Museum of China State Key Laboratory of Systematic and Evolutionary Botany Institute of Botany Chinese Academy of Sciences

The Upper Miocene Xiaohe Formation of the Yuanmou Basin in Yunnan Pro- vince, southwestern China, is famous for its hominoid fauna and is important for studying the Late Cenozoic human and mammal evolution. Abundant fossil wood was found associated with this fauna, which provided important evidence for palaeoenvironmental reconstruction of the basin. Among the fossil wood, two different taxa have been identified namely, Quercoxylon sp. （Fagaceae） and Pterocarya sp. （Juglandaceae）. Based on the habitats of their Nearest Living Relatives （NRLs）, it is suggested that upland subtropical evergreen broad-leaved forest dominated by QuercuslLithocarpus was common around the basin, while a lowland deciduous broad-leaved forest dominated by Pterocarya was present on the river bank of the basin during the Late Miocene.

关键词： fossil wood Quercoxylon Pterocarya palaeovegetation Late Miocene,Yuanmou Basin

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Efficacy of early lifestyle intervention on metabolic syndrome

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Journal of Geriatric Cardiology 2010年第1期7卷 14-20页

作者： Gui-Lan Zhang Gang Guo ye-Ping cheng Health Examination Center Xiaogan Hospital Affiliated to the Huazhong University of Science ＆ TechnologyXiaogan 432100 China Department of Physical Education Xiaogan College Xiaogan 432100. China

Objective Intensive lifestyle intervention significantly reduces the progression to diabetes in high-risk individuals. This study aimed to investigate the efficacy of early lifestyle intervention on high-risk groups of metabolic syndrome. Methods In a two-arm randomized controlled 1-year trial, we compared the effectiveness of a general recommendation-based program of lifestyle intervention carded out by wained professionals versus standard unstructured information given by physicians at reducing the prevalence of multiple metabolic and inflammatory abnormalities in 306 adults aged 45-64 years in Xiaogan city, China. Results At baseline, clinical/ anthropometric/laboratory and lifestyle characteristics of the intervention （n= 153 ） and control （n= 153） groups were not significantly different. The former significantly reduced total/saturated fat intake and increased polyunsaturated fat/fiber intake and exercise level compared to the controls. Weight, waist circumference, high-sensitivity C-reactive protein, and most of the metabolic syndrome components decreased in the intervention group and increased in the controls after 12 months. Lifestyle intervention significantly reduced metabolic syndrome （OR=0.28; 95% CI 0.18-0.44）, with a 31% （95% C121-41） absolute risk reduction, corresponding to 3.2 （95% CI, 2-5） patients needing to be treated to prevent 1 case after 12 months. The intervention significantly reduced the prevalence of central obesity （OR=0.33; 95% CI, 0.20-0.56）, and hypertriglyceridemia （OR=0.48; 95% CI, 0.31-0.75） and the incidence of diabetes （OR=0.23; 95% CI, 0.06-0.85）. Conclusions A lifestyle intervention based on general recommendations was effective in reducing multiple metabolic/inflammatory abnormalities. The usual care by clinical physicians was ineffective at modifying progressive metabolic deterioration in high-risk individuals （J Geriatr Cardio12010; 7：10-16）.

关键词： lifestyle intervention metabolic syndrome diabetes dyslipidemia

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Study on Preparation and Properties of Polyether Polytriazole Elastomers

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Chinese Journal of Polymer Science 2015年第4期33卷 597-606页

作者：翟进贤 Zheng-yang Qu ye-cheng Zou Xiao-yan Guo Rong-jie Yang School of Materials Beijing Institute of Technology

To explore the application of click chemistry in the field of elastomer materials, propargyl-terminated ethylene oxide-tetrahydrofuran copolymer （PTP（E-co-T）） was prepared from hydroxyl-terminated ethylene oxide-tetrahydrofuran copolymer （P（E-co-T）） by end-etherisation modification. FTIR and ^13C-NMR results indicate that P（E-co-T）-terminated hydroxyl was etherified thoroughly, yielding the target product PTP（E-co-T）, and the content of terminated alkynyl of PTP（E-co-T） was evaluated to be 0.428 mmol.g^-l. Using a polyazide compound as a cross-linker, polytriazole elastomers with various functional molar ratio （R） values were prepared from PTP（E-co-T） by virtue of the CuAAC reaction. Mechanical property tests indicate that with the increase in R, the modulus E and stress Orb of the polytriazole elastomers first increase and subsequently decrease, whereas the strain first decreases and later increases. The mechanical properties of the polytriazole elastomers show a parabolic dependence on the R value. Near the stoichiometric ratio, E and Orb show maxima and the strain εb shows a minimum. Swelling tests demonstrate that the apparent molecular weight of polytriazole elastomer strands also first decreases and subsequently increases. At the stoichiometric ratio, the network structure possesses strands with a minimum apparent molecular weight and a maximum apparent density. Dynamic mechanical analysis reveals that the polytriazole elastomers presented damping peaks at approximately -64℃, corresponding to the glass transition of copolyether strands, and the elastomer exhibited the lowest dissipation factor tanδ at the stoichiometric ratio. Thermal analysis suggests that the weight-loss process of the polytriazole elastomer is characteristic of one-step decomposition, and the elastomer begins to decompose from polyether strands, not triazole groups.

关键词： Click chemistry Polytriazole Elastomers PTP(E-co-T).

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Synthesis and biological evaluation of 12-N-p-chlorobenzyl sophoridinol derivatives as a novel family of anticancer agents

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Acta Pharmaceutica Sinica B 2016年第3期6卷 222-228页

作者： Chongwen Bi cheng ye Yinghong Li Wuli Zhao Rongguang Shao Danqing Song Institute of Medicinal Biotechnology Chinese Academy of Medical Science & Peking Union Medical College Tianjin Medical University General Hospital

Taking 12-N-p-chlorobenzyl sophoridinol 2 as a lead, a series of novel sophoridinic derivatives with various 30-substituents at the 11–side chain were synthesized and evaluated for their anticancer activity from sophoridine(1), a natural antitumor medicine. Among them, the sophoridinic ketones 5a–b, alkenes 7a–b and sophoridinic amines 14a–b displayed reasonable antiproliferative activity with IC50 values ranging from 3.8 to 5.4 μmol/L. Especially, compounds 5a and 7b exhibited an equipotency in both adriamycin(AMD)-susceptible and resistant MCF-7 breast carcinoma cells,indicating a different mechanism from AMD. The primary mechanism of action of 5a was to arrest the cell cycle at the G0/G1 phase, consistent with that of parent compound 1. Thus, we consider 12-chlorobenzyl sophoridinic derivatives with a tricyclic scaffold to be a new class of promising antitumor agents with an advantage of inhibiting drug-resistant cancer cells.

关键词： Sophoridinic derivatives Synthesis Structure–activity relationship Anticancer Drug resistance

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A survey of ventilation strategies during cardiopulmonary resuscitation

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World Journal of Emergency Medicine 2019年第4期10卷 222-227页

作者： ye-cheng Liu Yan-meng Qi Hui Zhang Joseph Walline Hua-dong Zhu Department of Emergency Medicine Peking Union Medical College HospitalBeijingChina Accident and Emergency Medicine Academic Unit Prince of Wales HospitalThe Chinese University of Hong KongHong KongChina

BACKGROUND:Many controversies still exist regarding ventilator parameters during cardiopulmonary resuscitation(CPR).This study aimed to investigate the CPR ventilation strategies currently being used among physicians in Chinese tertiary ***:A survey was conducted among the cardiac arrest team physicians of 500 tertiary hospitals in China in August,*** data included physician and hospital information,and preferred ventilation strategy during ***:A total of 438(88%)hospitals completed the survey,including hospitals from all 31 Chinese mainland *** 41.1%of respondents chose delayed or no ventilation during CPR,with delayed ventilations all starting within 12 *** all the respondents who provided ventilation,83.0%chose to strictly follow the 30:2 strategy,while 17.0%chose ventilations concurrently with uninterrupted *** 38.3%respondents chose to intubate after initiating CPR,while 61.7%chose to intubate immediately when resuscitation *** bagvalve-mask ventilation,only 51.4%of respondents delivered a frequency of 10 breaths per *** terms of ventilator settings,the majority of respondents chose volume control(VC)mode(75.2%),tidal volume of 6–7 mL/kg(72.1%),PEEP of 0–5 cmH2O(69.9%),and an FiO2 of 100%(66.9%).However,62.0%of respondents had mistriggers after setting the ventilator,and 51.8%had high pressure ***:There is a great amount of variability in CPR ventilation strategies among cardiac arrest team physicians in Chinese tertiary *** are needed with specific recommendations on ventilation during CPR.

关键词： Cardiopulmonary resuscitation Ventilation strategy Questionnaire survey Cardiac arrest team

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Analysis of Paraquat Intoxication Epidemic (2002-2011) within China

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Biomedical and Environmental Sciences 2013年第6期26卷 509-512页

作者： YIN Yu GUO Xiang ZHANG Shou Lin SUN cheng ye National Institute of Occupational Health and Poison Control Chinese Center for Disease Control and Prevention

Paraquat, is a Bipy herbicide have been widely used in last decade in China. Because of its high human toxicity and mortality characteristics, paraquat has been gained considerable attention in recent years. In order to evaluate the epidemic status of paraquat harm to human health in China, 24 h hotline information about paraquat intoxication consultation from January Ist, 2002 to December 31st, 2011 was collected by experienced practitioners in the Poison Control Center （National Poison Control Center, NPCC）

关键词： Analysis of Paraquat Intoxication Epidemic

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Total laparoscopic segmental gastrectomy for gastrointestinal stromal tumors: A case report

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World Journal of Clinical Cases 2020年第15期8卷 3365-3371页

作者： Yi-Xing Ren Ming He Peng-cheng ye Shou-Jiang Wei Department of General Surgery and Institute of Hepato-Biliary-Pancreas and Intestinal Disease Affiliated Hospital of North Sichuan Medical CollegeNanchong 637000Sichuan ProvinceChina

BACKGROUND Gastrointestinal stromal tumors are lesions that originate from digestive tract *** laparoscopic techniques,including local resections,wedge resections and partial gastrectomies,have been used ***,there are no reports on laparoscopic segmental gastrectomy for gastrointestinal stromal *** SUMMARY We present our analysis of 17 patients who were admitted to our hospital from January 2014 to December *** tumors were located in the corpus and antrum of the stomach,close to the lesser curvature of the *** tumors originated from the anterior wall in nine cases and from the posterior wall of the stomach in eight *** segmental gastrectomy and end-to-end anastomosis between the proximal and the distal residual stomach were used in all *** mean operative time was 112.4 *** mean length of hospital stay was 4.6 *** operative blood loss was 73.5 *** were no leaks,no postoperative bleeding nor need for *** postoperative follow-up was 35.4 *** Visick grading index showed fewer gastrointestinal symptoms 3 mo after *** patients(11.8%)had reflux esophagitis and *** Laparoscopic segmental gastrectomy may be a new function-preserving gastrectomy that is feasible for treatment of gastrointestinal stromal tumors that grow in the middle third of the stomach and on the lesser stomach curvature.

关键词： Gastrointestinal stromal tumors Laparoscopy Segmental gastrectomy Digestive tract Case report

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Spatiotemporal Distribution and Epidemiological Characteristics of Hospital Admissions for Carbon Monoxide Poisoning in Guangdong,China,2013-2020

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Biomedical and Environmental Sciences 2022年第10期35卷 943-953页

作者： XIAO Bin ZHANG You Miao ZHOU Jing XU cheng Dong HU Wei WEN Wei CHEN Jia Bin SUN cheng ye National Institute for Occupational Health and Poison Control Chinese Center for Disease Control and PreventionBeijing 100050China Guangdong Province Hospital for Occupational Disease Prevention and Treatment Guangdong Provincial Key Laboratory of Occupational Disease Prevention and TreatmentGuangzhou 510300GuangdongChina School of Public Health Sun Yat-sen UniversityGuangzhou 510030GuangdongChina State Key Laboratory of Resources and Environmental Information System Institute of Geographic Science and Natural Resource ResearchChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100101China Commission Affairs Center of Health Commission of Guangdong Province Guangzhou 510060GuangdongChina

Objective This study aimed to determine the spatiotemporal distribution and epidemiological characteristics of hospital admissions for carbon monoxide poisoning(COP)in Guangdong,China,from 2013 to *** Data on age-and sex-specific numbers of hospital admissions due to COP in Guangdong(2013-2020)were *** temperatures were downloaded through the China Meteorological Data Sharing Service *** analyzed temporal trends through time series decomposition and used spatial autocorrelation analysis to detect spatial *** distributed lag nonlinear model was used to quantify the effects of *** There were 48,854 COP admissions over the study *** sex ratio(male to female)was1:*** concentration ratios(M)ranged from *** highest risk occurred in January(season index=3.59).Most cases were concentrated in the northern mountainous areas of Guangdong with high-high *** in the study region showed significant spatial autocorrelation,and the global Moran’s I value of average annual hospital admission rates for COP was 0.447(P<0.05).Low temperatures were associated with high hospital admission rates for COP,with a lag lasting 7 *** a lag of 0 days,the effects of low temperatures[5th(12℃)]on COP were 2.24-3.81,as compared with the reference temperature[median(24℃)].Conclusion COP in Guangdong province showed significant temporal and spatial *** temperature was associated with a high risk of COP,and the influence had a lag lasting 7 days.

关键词： Carbon monoxide poisoning Hospitalization Distributed lag nonlinear model Spatialtemporal model

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