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卵巢储备功能减退针灸诊疗专家共识

湖南中医药大学学报 2024年第4期44卷 612-616页

作者：卵巢储备功能减退针灸诊疗专家共识小组石文英刘小娟不详湖南中医药大学第一附属医院

卵巢储备功能减退(diminished ovarian reserve,DOR)是严重影响女性生殖健康及生育能力的一类妇科疾病,以卵母细胞数量减少和质量下降为主要特征。针灸治疗DOR有一定的优势,近年来,针灸诊疗DOR的整体水平在不断提升,体现在对疾病的认识... 详细信息

卵巢储备功能减退(diminished ovarian reserve,DOR)是严重影响女性生殖健康及生育能力的一类妇科疾病,以卵母细胞数量减少和质量下降为主要特征。针灸治疗DOR有一定的优势,近年来,针灸诊疗DOR的整体水平在不断提升,体现在对疾病的认识不断深入、中医辨病辨证不断优化、针灸治疗方法多样化以及治疗时机精准化等方面。因此,集结针灸及妇科领域专家,以德尔菲问卷调查的形式,基于专家的临床诊疗经验,对针灸干预DOR患者的方案进行调查和整理,制定DOR针灸诊疗共识,以进一步提高DOR的临床疗效,推广针灸应用。

关键词：卵巢储备功能减退针灸诊疗共识治疗方案德尔菲问卷调查

Studies on the Relationship between Urokinase Plasminogen Activator(uPA)and Human Sperm Motility

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Journal of Huazhong University of Science and Technology(Medical Sciences) 1997年第4期17卷 213-217页

作者：黄勋彬夏文家熊承良肖敦振沈继云周洁玲 Center of reproductive Medicine Tongji Medical University Wuhan

To clarify the role of urokinase plasminogen activator(uPA) in the mechanisms of regulating sperm motility and the ability of fertilizing, we investigated the quantities and activities of uPA in human seminal Plasma and on the membrane of *** were harvested from 22 infertile patients with asthenospermia and 20 healthy fertile men according to WHO standards. To quantify the membrane-bound uPA in the samples, polyclonal antibodies against human urokinase were employed by means of a sandwich ELISA. The uPA activities in seminal plasma and on the surface of spermatozoa were determined using Agarose-Fibrine-Plate method and the experiment of immunological identification with polyclonal antibodies against urokinase. In lysates of spermatozoa, significantly lower levels of uPA(23. 1±7.35 mu/106 cells ) and uPA activity (5.13±3.85 mu/106 cells) were found in patient group as compared to healthy fertile men exhibiting normospermia (29. 89±9. 40 mu/105 cells and 10. 17±6. 18 mu/106 cells). In seminal plasma, uPA activity in patient group (2134±1581. 3 IU/L)was also found significantly lower than that of normal group (3365±1859. 5 IU/L). Positive correlations were observed between sperm motility and uPA quantities (r=0. 48, P＜0. 005), as well as with uPA activities (r= 0. 45,P＜0. 005).Thus, it is inferred that membrane associated uPA on human spermatozoa may be related directly to sperm motility and fertility.

关键词： urokinase plasminogen activator sperm motility asthenospermia

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辅助生殖领域拮抗剂方案标准化应用专家共识

中华生殖与避孕杂志 2022年第2期42卷 109-116页

作者：中国女医师协会生殖医学专业委员会专家共识编写组李蓉甄秀梅杨蕊不详北京大学第三医院

随着辅助生殖技术的飞速发展,寻求高效与安全并重的促排卵方案是辅助生殖医生的不断追求。目前,拮抗剂方案因其诸多优势而受到临床医生的青睐。为促进拮抗剂方案的标准化应用,本共识全面综述了拮抗剂方案使用节点,讨论和解决在拮抗剂的... 详细信息

随着辅助生殖技术的飞速发展,寻求高效与安全并重的促排卵方案是辅助生殖医生的不断追求。目前,拮抗剂方案因其诸多优势而受到临床医生的青睐。为促进拮抗剂方案的标准化应用,本共识全面综述了拮抗剂方案使用节点,讨论和解决在拮抗剂的应用上存在的主要问题,为临床医师拮抗剂方案的应用提供指导和建议。

关键词：生殖技术,辅助受精,体外单精子显微注射,卵胞质内促排卵促性腺激素释放激素拮抗剂

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前列腺癌规范化标本取材及病理诊断共识

中华病理学杂志 2016年第10期45卷 676-680页

作者：中华医学会病理学分会泌尿男性生殖系统疾病病理专家组中华医学会病理学分会泌尿男性生殖系统疾病病理专家组

前列腺癌是一组发生于前列腺内的恶性上皮性肿瘤的统称，位居男性最常见恶性肿瘤的第二位，根据我国近年来的癌症统计数据，前列腺癌的发病率逐年递增。

关键词：前列腺癌病理诊断恶性上皮性肿瘤取材标本前列腺内恶性肿瘤统计数据

ACTION OF BSNXD AND DHEA IN PREVENTING AND CURING POSTMENOPAUSAL OSTEOPOROSIS

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ACTION OF BSNXD AND DHEA IN PREVENTING AND CURING POSTMENOPA...

关于筛查合格供精志愿者的标准更新的中国专家共识

The 5th International Conference on reproductive Endocrinology

作者： Wang Yu-dong Li Da-jin Zhu Ying Laboratory for reproductive Immunology Hospital and Institute of Obstetrics & Gynecology Shanghai Medical College Fudan University Shanghai China.

＜正＞Objectives:To investigate the effect of Bu-shen-ning-xin （补肾宁心） decoction （BSNXD） and dehydroepiandrosterone （DHEA） on postmenopausal osteoporosis （PMOP）. Methods:Female BALB/c mice （8～9 months age） were divided randomly into six groups containing ten mice per *** of group 1 were left intact and served as a normal control group （NC group）, mice of group 2 were operated without lesion of ovarian （Sham operation group）.Mice of groups 3～6 were ovariectomized and,after a 7-day delay to allow for producing osteoporosis,were afforded with

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中国计划生育和妇产科 2021年第9期13卷 7-10,15页

作者：中国妇幼保健协会辅助生殖技术监测与评估专业委员会精子库与生殖男科学组专家共识工作组张欣宗朱文兵黄川周文珺罗雪峰刘谦不详广东省生殖医院广东广州516000 中信湘雅生殖与遗传专科医院湖南长沙410000

本共识聚焦供精志愿者检查标准,由中国妇幼保健协会辅助生殖技术监测与评估专业委员会精子库与生殖男科学组发起,组织了国内人类精子库领域的专家成立专家共识工作组后反复讨论撰写,内容涉及供精志愿者检查的各方面,包括供精志愿者年龄... 详细信息

本共识聚焦供精志愿者检查标准,由中国妇幼保健协会辅助生殖技术监测与评估专业委员会精子库与生殖男科学组发起,组织了国内人类精子库领域的专家成立专家共识工作组后反复讨论撰写,内容涉及供精志愿者检查的各方面,包括供精志愿者年龄、精液参数、精子形态率的选择,供精志愿者体检标准的补充,供精志愿者检查结果标准解读3个内容和9个点.

关键词：人类精子库供精志愿者基本标准专家共识

Timing of IUI Treatment after hCG Administration 1-48h Affecting Pregnancy Rate

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Journal of Reproduction and Contraception 2008年第3期19卷 147-151页

作者： Fan YANG Hui JIN Li-ping ZHU Kun-ming LI Jian-zhi YANG Zhi-qin CHEN Xiao-ming TENG Hui-fen CHEN Yu WANG Zu-mei SHI reproductive Center First Maternity and Infant Health Hospital Shanghai Tongji University Shanghai 200040 China Shanghai Women＇ health Institute Shanghai 200040 China

Objective To compare the different time of administration of hCG affecting pregnancy rate of IUI. Methods A total of 189 infertile couples underwent 331 cycles of lUI with husband＇s sperm. They were separated into 3 groups according to the time of hCG administration in IUI： hCG 1-23 h （group A）; hCG 24-36 h （group B）; hCG 37-48 h （group C）. Results There were no statistical differences among 3 groups. None of the other relative factors, such as the female age, the different methods of ovulation and the cause of infertility, showed differences in pregnancy rate among 3 groups. Conclusion IUI can be performed any time after administration of hCG （1-48 h）.

关键词： infertility artificial insemination oligospermia

Evaluation of Adiponectin, Resistin, IL-6, TNF-α in Obese and Non-obese Women with Polycystic Ovary Syndrome

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Journal of Reproduction and Contraception 2012年第4期23卷 237-244页

作者： Yu-xia WANG Wei-jie ZHU Department of Obstetrics and Gynecology the First Affiliated Hospital Jinan University Institute of reproductive Immunology Jinan University

Objective To evaluate possible clinical effects of adiponectin, resistin, 1L-6, and TNF-a in obese and non-obese patients with polycystic ovary syndrome （PCOS）. Methods Seventy selected PCOS patients were recruited for this study, and were divided into two groups based on their body mass index （BM1）： 35 obese （BM1 25 kg/m2, group A）, 35 non-obese （BMI〈25 kg/me, group B）. In addition, 35 healthy non-obese women （BMI〈25 kg/m2） were enrolled as the control （group C）. Serum levels of FSH, LH, T, glucose, insulin, adiponectin, resistin, 1L-6, TNF-a. were detected, and compared the differences of them among three groups. Results Blood glucose levels among three groups had no difference （P〉0.05）. Blood insulin level was significantly greater in group A than in group B or group C （P〈0.05）, and a significant difference existed between group B and group C （P〈0. 05）. The ratio of glucose/insulin was significantly higher in group A than in group B or group C （P〈0.05）, and the ratio in group B was significantly higher than that in group C （P〈0.05）. Adiponectin level was significantly lower and resistin level was significantly higher in group A than in group B or group C （P〈0.05）. IL-6 level in group C was significantly lower than that in group A or group B （P〈0.05）, and significant difference was found between group A and group B （P〈0.05）. TNF-a level was a slight high in group B, whereas there was no statistical difference among three groups （P〉0.05）. Conclusion Disturbances of some metabolic and inflammatory adipokines could involve the pathogenesis of PCOS in both obese and non-obese women. Low-grade chronic inflammation might have negative effects on the development of PCOS in non- obese women.

关键词： polycystic ovary syndrome (PCOS) adipokines obesity

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无精子症诊疗中国专家共识

中华生殖与避孕杂志 2021年第7期41卷 573-585页

作者：中国医师协会生殖医学专业委员会生殖男科学组无精子症诊疗中国专家共识编写组熊承良李铮洪锴潘峰安庚陈向锋李朋刘贵华陆金春尹太郎张欢不详华中科技大学同济医学院上海交通大学附属第一人民医院北京大学第三医院华中科技大学同济医学院附属协和医院广州医科大学附属第三医院上海交通大学医学院附属仁济医院中山大学附属第六医院东南大学附属中大医院武汉大学人民医院中信湘雅遗传与生殖专科医院

无精子症是男性不育症中最严重的一种情况。为进一步规范无精子症的诊疗过程,由中国医师协会生殖医学专业委员会生殖男科学组发起,组织无精子症领域的专家成立编写小组,基于临床实践和已发表文献共同讨论和制定此共识。共识涉及梗阻性... 详细信息

无精子症是男性不育症中最严重的一种情况。为进一步规范无精子症的诊疗过程,由中国医师协会生殖医学专业委员会生殖男科学组发起,组织无精子症领域的专家成立编写小组,基于临床实践和已发表文献共同讨论和制定此共识。共识涉及梗阻性无精子症、非梗阻性无精子症的诊断与治疗策略,以及无精子症的遗传学咨询、与其他病因相关联的无精子症、辅助生殖技术、生育力保存和健康管理等方面内容,旨在为从事生殖医学、男科学专业医务人员提供专家咨询建议和诊疗参考。

关键词：无精子症梗阻性无精子症非梗阻性无精子症生殖技术,辅助专家共识