检索结果-南通市图书馆

维普期刊数据库博看期刊

在线全文

学校读者我要写书评

暂无评论

环旧新居

现代装饰（家居） 2016年第12期 80-87页

作者： yasemin Arpac Sabahattin Emir Ali Bekman 范嘉苑土耳其Ofist

土耳其Ofisf室内设计工作室近期完成了一个位于伊斯坦布尔的住宅改造项目，房子建于70年代，从露台能眺望美丽的山林及海湾景色，如今被改造成一间富有现代气息的住宅。设计团队在进行空间改造的同时，还将住宅周围的环境、自然、人文... 详细信息

土耳其Ofisf室内设计工作室近期完成了一个位于伊斯坦布尔的住宅改造项目，房子建于70年代，从露台能眺望美丽的山林及海湾景色，如今被改造成一间富有现代气息的住宅。设计团队在进行空间改造的同时，还将住宅周围的环境、自然、人文元素融入设计之中，以此向房子当年的原始设计及细节致敬。

关键词：设计工作室改造项目伊斯坦布尔空间改造住宅土耳其房子室内

维普期刊数据库

Hypoxia and cytokines regulate carbonic anhydrase 9 expression in hepatocellular carcinoma cells in vitro

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Oncology 2012年第6期3卷 82-91页

作者： Feray Kockar Hatice Yildrim Rahsan Ilikci Sagkan Carsten Hagemann yasemin Soysal Jelena Anacker Ahmed Ayad Hamza Dirk Vordermark Michael Flentje Harun M Said Department of Biology Faculty of Art and Science Balikesir University Department of Immunology and Allergy Diseases Gulhane Military Medical Academy Tumorbiology Laboratory Department of Neurosurgery University of Würzburg Faculty of Medicine Department of Medical Genetics Afyon Kocatepe University Department of Obstetrics and Gynaecology University of Würzburg School of Medicine Southern Illinois University Department of Radiation Oncology University-Halle-Wittenberg Department of Radiation Oncology University of Wuerzburg

AIM: To study the expression of carbonic anhydrase(CA) 9 in human hepatocellular carcinoma(HCC) ***: We studied CA9 protein, CA9 m RNA and hypoxia-inducible factor-1 alpha(HIF-1α) protein levels in Hep3 B cells exposed in different parallel approaches. In one of these approaches, HCC cells were exposed to extreme in vitro hypoxia(24 h 0.1% O2) without or with interleukin(IL)-1, IL-6, tumor necrosis factoralpha(TNF-α) and transforming growth factor-beta(TGF-β) stimulation for the same hypoxic exposure time or exposed to normoxic oxygenation conditions without or with cytokine ***: The tumour cell line analysed showed a strong hypoxic CA9 m RNA expression pattern in response to prolonged severe hypoxia with cell-line specific patterns and a marked induction of CA9 protein in response to severe hypoxia. These results were paralleled by the results for HIF-1α protein under identical oxygenation conditions with a similar expression tendency to that displayed during the CA9 protein expression experimental series. Continuous stimulation with the cytokines, IL-1, IL-6, TNF-α and TGF-β, under normoxic conditions significantly increased the carbonic anhydrase 9 expression level at both the protein and m RNA level, almost doubling the CA9 m RNA and CA9 and HIF-1α protein expression levels found under hypoxia. The findings from these experiments indicated that hypoxia is a positive regulator of CA9 expression in HCC, and the four signal transduction pathways, IL-1, IL-6, TNF-α and TGF-β, positively influence CA9 expression under both normoxic and hypoxic ***: These findings may potentially be considered in the design of anti- cancer therapeutic approaches involving hypoxia-induced or cytokine stimulatory effects on expression. In addition, they provideevidence of the stimulatory role of the examined cytokine families resulting in an increase in CA9 expression under different oxygenation conditions in human cancer, especially HCC, and

关键词： Angiogenesis Carbonic anhydrase 9 Hypoxia Hypoxia-inducible factor-1 alpha Oxygen Radiotherapy Transforming growth factor-beta Tumour microenviroment

Increased serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in patients with biopsy-proven nonalcoholic fatty liver disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第26期21卷 8096-8102页

作者： Oguzhan Ozturk Yasar Colak Ebubekir Senates Yusuf Yilmaz Celal Ulasoglu Levent Doganay Seyma Ozkanli yasemin Musteri Oltulu Ender Coskunpinar Ilyas Tuncer Department of Gastroenterology Goztepe Teaching and Research HospitalIstanbul Medeniyet University Department of Gastroenterology Marmara University School of MedicineIstanbulTurkey Institute of Gastroenterology Marmara University Department of Pathology Goztepe Teaching and Research HospitalIstanbul Medeniyet University Department of Molecular Medicine Institute of Experimental Medicine ResearchIstanbul University

AIM: To analyze the relationship between the serum lectin-like oxidized low-density lipoprotein receptor-1(LOX-1) levels and clinical and histopathological features of biopsy-confirmed nonalcoholic fatty liver disease(NAFLD) ***: Fifty-three consecutive,biopsy-proven NAFLD patients(31 males and 22 females,mean age 42.5 ± 9.6 years) and 26 age- and gender-matched,healthy controls(14 males and 12 females,mean age 39 ± 10.7 years) were *** patientswith NAFLD were consecutive patients who had been admitted to the hepatology outpatient clinic within the last year and had been diagnosed with NAFLD as the result of liver *** healthy controls were individuals who attended the outpatient clinic for routine health control and had no known chronic *** histological evaluation was conducted according t o t he N AF LD ac t ivi ty scoring syst em recommended by The National Institute of Diabetes and Digestive and Kidney Diseases Nonalcoholic Steatohepatitis Clinical Research *** serum LOX-1 levels were measured using an ELISA kit(Life Science ***,Catalog No.E1859Hu) in both patients and healthy controls.A receiver operating characteristic(ROC) curve analysis was used to identify the optimal cutoff value of LOX-1 and thereby distinguish between patients with nonalcoholic steatohepatitis(NASH) and healthy controls.A P-value < 0.05 was considered statistically ***: NAFLD and healthy control groups were similar in terms of age and *** patients consisted of 8 patients with simple steatosis(15%),27 with borderline NASH(51%) and 18 with definitive NASH(34%).Metabolic syndrome was found in 62.2% of the patients with *** mean serum LOX-1 level in biopsy-proven NAFLD patients was 8.49 ± 6.43 ng/m L compared to 4.08 ± 4.32 ng/m L in healthy controls(P = 0.001).The LOX-1 levels were significantly different between controls,simple steatosis and NASH(borderline+definite) cases(4.08 ± 4.32 ng/m L,6.1 ± 6.16 ng/

关键词： Insulin resistance Liver fibrosis Metabolicsyndrome Nonalcoholic fatty liver disease Steatohepatitis

Treatment of Crohn's disease and familial Mediterranean fever by leukopheresis:Single shot for two targets

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第13期21卷 4078-4081页

作者： Mahmut Yuksel Fatih Saygili Orhan Coskun Nuretdin Suna Mustafa Kaplan Ufuk Baris Kuzu Zeki Mesut Yalin Kilic yasemin Ozderin Ozin Ertugrul Kayacetin Department of Gastroenterology Turkiye Yuksek Ihtisas Training and Education HospitalAnkara 06230Turkey

Coexistence of Crohn's disease(CD) and familial Mediterranean fever(FMF) is a rare condition and knowledge about this clinical situation is limited with a few case reports in the literature. The treatment of both diseases depends on their individual therapies. However, it is very hard to deal with this coexistence when CD is refractory to standard therapies. Ongoing activity of CD triggers the clinical attacks of FMF and the symptoms like abdominal pain interfere with both disease presentations which can cause problems about diagnostic and therapeutic approach. The main therapeutic agent for FMF is colchicine and diarrhea is the most common side effect of this drug. This side effect also causes problems about management of these diseases when both of them are clinically active. Here we report probably the first case in the literature with coexisting CD and FMF who was successfully treated by leukopheresis since he was refractory to conventional therapies for CD.

关键词： Crohn’s disease Familial Mediterranean fever Leuko

口服降糖药和胰岛素对眼表治疗的影响(英文)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

国际眼科杂志 2013年第9期13卷 1747-1750页

作者： Burin Kklü akιr yasemin Aslan Katιrcιoglu Nurten nlü Hüseyin stün Remzi Kasιm Sunay Duman Bahcelievler市Orkide大街39/5号土耳其巴勒克埃西尔10050 安卡拉培训和研究医院眼科土耳其安卡拉06600

目的:描述和对比口服降糖药(OAD)和胰岛素治疗2型糖尿病患者眼表的效果。方法:在安卡拉卫生部培训和研究医院就诊的20例40眼口服降糖药患者,20例40眼胰岛素治疗患者,对照组的10例非糖尿病人作为研究对象。对所有患者进行常规眼科检查,Sc... 详细信息

目的:描述和对比口服降糖药(OAD)和胰岛素治疗2型糖尿病患者眼表的效果。方法:在安卡拉卫生部培训和研究医院就诊的20例40眼口服降糖药患者,20例40眼胰岛素治疗患者,对照组的10例非糖尿病人作为研究对象。对所有患者进行常规眼科检查,Schirmer试验,泪膜破裂时间分析和结膜印迹细胞学分析.比较三组的泪液功能参数,杯状细胞密度和鳞状上皮化生等级。记录视网膜病变及眼表疾病之间的关系。结果:口服降糖药患者泪膜破裂时间值明显低于其他组(P<0.05)。三组的杯状细胞密度和鳞状上皮化生等级相近。上皮细胞稍大,呈现更多的多边形的眼的中位数级为1级,并且嗜酸性染色胞浆和杯状细胞数量减少。视网膜病变与眼表疾病不相关。结论:口服降糖药患者的角膜前泪膜稳定性比其他组差。各组的印迹细胞学分析结果相似。

关键词：眼表糖尿病印迹细胞学

维普期刊数据库

在线全文

学校读者我要写书评

暂无评论

开窗畸形之基底动脉并发颅内多发性动脉瘤

实用放射学杂志 2003年第9期19卷 863-864页

作者：李文彬,李明华,H Grady Daniel,Dee H Wu,L.Tytle,Rifat Karatas,yasemin Karatas,William TC Yuh University of Oklahoma Health Sciences Center Department of Radiology University of Oklahoma Health Sciences Center Department of Radiology University of Oklahoma Health Sciences Center 200233 200233 Oklahoma City OK73104 USA Oklahoma City 上海交通大学附属第六人民医院放射科 OK73104 USA Oklahoma City OK73104 USA Oklahoma City OK73104 USA Oklahoma City OK73104 上海交通大学附属第六人民医院放射科 USA Oklahoma City OK73104 USA Department of Radiology University of Oklahoma Health Sciences Center Department of Radiology University of Oklahoma Health Sciences Center Department of Radiology University of Oklahoma Health Sciences Center Department of Radiology

血管开窗畸形，也即血管局部节段性扩张，是一种罕见的先天性动脉变异。据一组尸体解剖的文献报道基底动脉的开窗畸形发生率为1.3%～5.3%；基底动脉开窗畸形的血管造影发生率为0.4%～0.6%。基底动脉开窗畸形并发颅内动脉瘤非常罕见，首... 详细信息

血管开窗畸形，也即血管局部节段性扩张，是一种罕见的先天性动脉变异。据一组尸体解剖的文献报道基底动脉的开窗畸形发生率为1.3%～5.3%；基底动脉开窗畸形的血管造影发生率为0.4%～0.6%。基底动脉开窗畸形并发颅内动脉瘤非常罕见，首例报道是1979年。虽然为一罕见病例，此病便在血管造影，外科手术或尸检中的表现仍有较多作者报道，尤以日本的文献报道最多。Campos等报道基底动脉近端开窗畸形并发动脉瘤的病例最多，为21例。尽管如此，基底动脉开窗畸形并发颅内多发性动脉瘤仍属罕见，本文就此病例的CT和CTA，DSA表现报告如下。

关键词：基底动脉开窗畸形多发动脉瘤颅内

Insight into orthodontic appliance induced pain:Mechanism,duration and management

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Anesthesiology 2016年第1期5卷 28-35页

作者： yasemin Kartal Omur Polat-Ozsoy Department of Orthodontics Baskent UniversityFaculty of Dentistry

Most of the orthodontic patients experience pain during treatment and this significantly influences their attitudes and the approach towards treatment. A number of factors that influence pain response include age, gender, personal pain threshold, mood and stress level of the person, cultural differences and types of orthodontic treatment. Pain is a often overlooked subject by orthodontists, it is nevertheless important to understand the source and mechanism of the pain that occurs during treatment, as well as the methods for managing and controlling this pain. This review attempts to overview the mechanism, duration and current management strategies of orthodontic treatment.

关键词： Orthodontic appliance Pain mechanism Orthodontic treatment Pain Pain management

含有0.8%精氨酸、PVM/MA共聚物、焦磷酸盐和0.05%氟化钠的新型脱敏漱口水的作用方式的研究

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

口腔护理用品工业 2014年第6期24卷 29-35页

作者： Sarita V.Melloa Evangelia Arvanitidoua Michael A.Stranicka Ramon Santanaa yasemin Kutesb Bryan Hueyb 高露洁-棕榄技术中心康涅狄格州大学化学材料与生物分子工程系

目的:经提出并证实,采用Pro-Argin TM漱口水工艺制成的含有0.8%精氨酸、PVM/MA共聚物、焦磷酸盐和0.05%氟化钠的精氨酸漱口水的作用方式,可利用多种体外技术产生封闭作用。方法:采用定量和定性实验室技术研究这种新型精氨酸漱口水的作... 详细信息

目的:经提出并证实,采用Pro-Argin TM漱口水工艺制成的含有0.8%精氨酸、PVM/MA共聚物、焦磷酸盐和0.05%氟化钠的精氨酸漱口水的作用方式,可利用多种体外技术产生封闭作用。方法:采用定量和定性实验室技术研究这种新型精氨酸漱口水的作用方式。利用共焦激光扫描显微镜检查(CSLM)和原子力显微镜检查(AFM)研究牙本质表面的水合层。化学分析电子光谱学(ESCA)、二次离子质谱学(SIMS)和近红外光谱学(NIR)提供了关于这种漱口水的化学性质的信息。结果:使用精氨酸漱口水后,采用CLSM观察暴露牙本质小管上的水合层的形成。经荧光研究证实,水合层可渗透到牙本质小管内壁。经AFM研究证实,精氨酸漱口水对牙本质表面具有亲合力,这与其粘合性质相一致。NIR表明,使用漱口水数次后,精氨酸会沉积下来,而ESCA/SIMS检测到磷酸基团和有机酸基团的存在,表明PVM/MA共聚物和焦磷酸盐是连同精氨酸一起沉积下来的。结论:研究表明:富含精氨酸层连同来自于含有0.8%精氨酸、PVM/MA共聚物、焦磷酸盐和0.05%氟化钠的无酒精漱口水的共聚物和磷酸盐离子一起沉积下来后,可封闭牙本质表面。

关键词：漱口水精氨酸牙齿敏感牙本质封闭

维普期刊数据库

Investigation of Wooden Beam Behaviors Reinforced with Fiber Reinforced Polymers

在线全文

学校读者我要写书评

暂无评论

Organic Polymer Material Research 2020年第1期2卷 1-7页

作者： Şemsettin KILINÇARSLAN yaseminŞİMŞEK TÜRKER Suleyman Demirel University Faculty of EngineeringDepartment of Civil EngineeringTurkey

Wood material can be demolished over time due to different environmental *** elements may need to be strengthened over time as a result of possible natural disasters or during *** are elements under load in the direction perpendicular to their ***,they are basically under the effect of *** the studies on the behavior of beams against bending test are examined,it is known that the bottom surface of the material generally *** this reason,fiber reinforced polymers(FRP)materials have been used in recent years to reinforce beam *** is a scientific fact that it is necessary to prefer FRPs for the solution of this problem,as well as their properties such as lightness,corrosion and flexibility,their application without disrupting the appearance of *** this study,it was aimed to investigate the effect of reinforcing wooden beams with fiber reinforced polymer materials with different properties on different bending behaviors such as load bearing capacity,ductility,modulus of *** was observed that the ductility and bearing capacity of wooden beams reinforced with fiber reinforced polymer materials increased significantly compared to non-reinforced beams.

关键词： Wood materials Beam FRP Reinforced Composite