检索结果-南通市图书馆

Tribochemical synthesis of functionalized covalent organic frameworks for anti-wear and friction reduction

Friction 2023年第10期11卷 1804-1814页

作者： Xiaozhi ZHANG Qi LU yaojie yan Tingting ZHANG Shujuan LIU Meirong CAI Qian YE Feng ZHOU Weimin LIU State Key Laboratory of Solidification Processing Center of Advanced Lubrication and Seal MaterialsSchool of Materials Science and EngineeringNorthwestern Polytechnical UniversityXi’an 710072China State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000China

Tribochemistry can be defined as a field dealing with the chemical reactions occurring in the friction zone,capable of catalyzing mechanical and physico-chemical changes in the friction contact area,facilitating the formation of tribo-films,which is also an efficient approach to fabricate novel innovative *** this paper,we report the successful synthesis of the silicon oil(SO)-functionalized covalent organic frameworks(COFs)prepared via the tribochemical method when subjected to the reciprocating friction;during the friction process,the rich aldehyde-terminated COFs can bond with amino SO via the Schiff base reaction between aldehyde group and amino group to obtain the desired functionalized COFs(SO@COF-LZU1).The tribochemical reaction progress was tracked through in-situ monitoring of the friction coefficient and the operating conditions during the entire friction ***,the friction coefficient continued to decrease until it finally stabilized as the reaction progressed,which revealed the formation of a protective ***,an approximate tribochemical model was presented,wherein the reaction mechanism was investigated and analyzed by employing structural analysis techniques like magic angle spinning nuclear magnetic resonance(MAS NMR),transmission electron microscopy(TEM),and X-ray photoelectron spectroscopy(XPS).Furthermore,the tribochemical-induced SO@COF-LZU1 exhibited remarkable tribological performance with a low friction coefficient of 0.1 and 95.5%reduction in wear volume when used as additives of 500SN base *** prime focus of our research was on the preparation and functionalization of COF materials via tribochemical reactions,unraveling a new avenue for the rational design and preparation of functional materials.

关键词： tribochemical reaction covalent organic frameworks(COFs) silicon oil(SO)functionalization lubricant additives tribological properties

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Excitonic devices based on two-dimensional transition metal dichalcogenides van der Waals heterostructures

引用

Frontiers of Chemical Science and Engineering 2024年第2期18卷 41-67页

作者： Yulun Liu yaojie Zhu Zuowei yan Ruixue Bai Xilin Zhang yanbo Ren Xiaoyu Cheng Hui Ma Chongyun Jiang College of Electronic Information and Optical Engineering Nankai UniversityTianjin 300350China School of Physical Science and Technology Tiangong UniversityTianjin 300387China

Excitonic devices are an emerging class of technology that utilizes excitons as carriers for encoding, transmitting, and storing information. Van der Waals heterostructures based on transition metal dichalcogenides often exhibit a type II band alignment, which facilitates the generation of interlayer excitons. As a bonded pair of electrons and holes in the separation layer, interlayer excitons offer the chance to investigate exciton transport due to their intrinsic out-of-plane dipole moment and extended exciton lifetime. Furthermore, interlayer excitons can potentially analyze other encoding strategies for information processing beyond the conventional utilization of spin and charge. The review provided valuable insights and recommendations for researchers studying interlayer excitonic devices within van der Waals heterostructures based on transition metal dichalcogenides. Firstly, we provide an overview of the essential attributes of transition metal dichalcogenide materials, focusing on their fundamental properties, excitonic effects, and the distinctive features exhibited by interlayer excitons in van der Waals heterostructures. Subsequently, this discourse emphasizes the recent advancements in interlayer excitonic devices founded on van der Waals heterostructures, with specific attention is given to the utilization of valley electronics for information processing, employing the valley index. In conclusion, this paper examines the potential and current challenges associated with excitonic devices.

关键词： excitonic devices van der Waals heterostructures transition metal dichalcogenides interlayer excitons valley-Hall effect optoelectronics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The AaBBX21–AaHY5 module mediates light-regulated artemisinin biosynthesis in Artemisia annua L.

引用

Journal of Integrative Plant Biology 2024年第8期66卷 1735-1751页

作者： Weizhi He Hang Liu Zhangkuanyu Wu Qing Miao Xinyi Hu Xin yan Hangyu Wen yaojie Zhang Xueqing Fu Li Ren Kexuan Tang Ling Li Frontiers Science Center for Transformative Molecules Joint International ResearchLaboratory of Metabolic and Developmental SciencesKey Laboratory of Urban Agriculture(South)Ministry of AgriculturePlant Biotechnology Research CenterFudan-SJTU-Nottingham Plant Biotechnology R&D CenterSchool of Agriculture and BiologyShanghai Jiao Tong UniversityShanghai 200240China Institute for Agri-Food Standards and Testing Technology Shanghai Academy of Agricultural SciencesShanghai 201403China

The sesquiterpene lactone artemisinin is an important anti-malarial component produced by the glandular secretory trichomes of sweet wormwood(Artemisia annua L.).Light was previously shown to promote artemisinin production,but the underlying regulatory mechanism remains *** this study,we demonstrate that ELONGATED HYPOCOTYL5(HY5),a central transcription factor in the light signaling pathway,cannot promote artemisinin biosynthesis on its own,as the binding of AaHY5 to the promoters of artemisinin biosynthetic genes failed to activate their *** analysis and yeast two-hybrid screening revealed the B-box transcription factor AaBBX21 as a potential interactor with ***21 showed a trichome-specific expression ***,the AaBBX21–AaHY5 complex cooperatively activated transcription from the promoters of the downstream genes AaGSW1,AaMYB108,and AaORA,encoding positive regulators of artemisinin ***,AaHY5 and AaBBX21 physically interacted with the *** E3 ubiquitin ligase CONSTITUTIVELY PHOTOMORPHOGENIC 1(COP1).In the dark,AaCOP1 decreased the accumulation of AaHY5 and AaBBX21 and repressed the activation of genes downstream of the AaHY5–AaBBX21 complex,explaining the enhanced production of artemisinin upon light *** study provides insights into the central regulatory mechanism by which light governs terpenoid biosynthesis in the plant kingdom.

关键词： AaBBX21 AaHY5 AaCOP1 Artemisia annua L. artemisinin biosynthesis light

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Effect of Ginkgo Biloba Leaf Dropping Pill Combined with Butylphthalide Capsule on Cognitive Dysfunction in Patients after Acute Ischemic Stroke and Its Impact on Serum Cytokines

引用

Journal of Biosciences and Medicines 2024年第7期12卷 252-262页

作者： yaojie Cai Yuping He Gang yang yan Chen Department of Neurology Zhuji Peoples Hospital of Zhejiang Province Shaoxing China Department of Neurosurgery Zhuji Peoples Hospital of Zhejiang Province Shaoxing China

Objective: To investigate the therapeutic effect of Ginkgo biloba extract dropping pills combined with butylphthalide capsules on cognitive dysfunction in patients after acute ischemic stroke (AIS) and its impact on serum cytokines CRP, IL-6, and Hcy. Methods: This study selected 76 patients with cognitive dysfunction after ischemic stroke who were hospitalized at Zhuji People’s Hospital from January 2023 to January 2024. The patients were divided into two groups. The control group was treated with butylphthalide capsules, while the combination group received Ginkgo biloba extract dropping pills in addition to the treatment given to the control group. The neurological function, cognitive function, activities of daily living, and levels of serum cytokines CRP, IL-6, and Hcy were compared between the two groups after 1 month and 3 months of treatment. Results: The NIHSS scores, MMSE scores, ADL scores, and levels of CRP, IL-6, and Hcy in both groups showed statistically significant differences compared to before treatment (P Conclusion: The combination of Ginkgo biloba extract dropping pills and butylphthalide capsules has a better therapeutic effect on cognitive dysfunction in patients after ischemic stroke. It can improve the neurological function and cognitive function of patients, enhance their ability to perform daily activities, and reduce inflammatory responses.

关键词： Acute Ischemic Stroke Ginkgo Biloba Leaf Drop Pills Butylphthalein Cognitive Impairment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Application of Time-Tracking Platform in the Reperfusion Treatment of Patients with Acute Ischemic Stroke in Primary Hospitals

引用

Journal of Biosciences and Medicines 2024年第7期12卷 230-238页

作者： yaojie Cai yan Chen Feng Fu Yuping He Department of Neurology Zhuji Peoples Hospital of Zhejiang Province Shaoxing China

Objective To explore the application effect of time tracking platform in improving the reperfusion treatment of patients with acute ischemic stroke in primary hospitals. Methods and Results Patients with acute ischemic stroke who carried out emergency intravenous thrombolysis and arterial thrombectomy in our hospital in 2021, 2022 and 2023 were selected. The time tracking mode was implemented, and the patients were recorded at each time node of the hospital and the whole-process digital management was conducted. Compared the mean DNT (Door to Needle Time) of intravenous thrombolysis in emergency stroke patients in 2021, 2022 and 2023, the total number of hospital cases within 4.5 h of onset, the total number of thrombolysis cases within 4.5 h of onset, the number of intravenous thrombolysis in 60 minutes of acute ischemic stroke, and the number of thrombolysis cases. The results show that from 2021 to 2023 our emergency stroke patients with intravenous thrombolysis average DNT shortened year by year, to the hospital within 4.5 h after the onset of the difference is statistically significant (all P < 0.05) conclusion through the application of stroke time tracking platform, is beneficial to shorten the treatment time of each link, can effectively reduce the hospital time delay, improve the rate of thrombolysis, improve the reperfusion of stroke centers in primary hospitals.

关键词： Time-Tracking Platform Acute Ischemic Stroke Thrombolysis Thrombectomy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于双准偶然连续体束缚态模式的传感与慢光研究

引用

激光与光电子学进展 2024年第13期61卷 399-407页

作者：陈莎刘钦柯李燕周尧杰陆振东罗晓清王新林南华大学电气工程学院湖南衡阳421001 南华大学核科学技术学院湖南衡阳421001 南华大学机械工程学院超快微纳技术与激光先进制造湖南省重点实验室湖南衡阳421001

近年来,光学超表面中的连续体束缚态(BIC)因其独特的性质而受到了广泛的关注。为了研究两个准偶然连续体束缚态(A-QBIC)模式之间相互作用诱导的新颖光学现象,提出一种方形纳米孔阵列全介质超表面。结果表明,在x偏振光和y偏振光入射时能... 详细信息

近年来,光学超表面中的连续体束缚态(BIC)因其独特的性质而受到了广泛的关注。为了研究两个准偶然连续体束缚态(A-QBIC)模式之间相互作用诱导的新颖光学现象,提出一种方形纳米孔阵列全介质超表面。结果表明,在x偏振光和y偏振光入射时能实现A-BIC现象,尤其在45°偏振光入射下可实现两个A-QBIC模式间的相互作用。利用能带理论和多极展开理论对A-QBIC模式进行分析,发现这两种模式均由环形偶极模式主导。重要的是,基于A-QBIC模式的高Q值特性,能够构建高灵敏度折射率传感,同时利用两个A-QBIC模式间具有灵活调谐度的相互作用特性,还能够实现类电磁诱导透明和可调的慢光。研究结果可为基于A-QBIC的高Q超构器件在高灵敏度折射率传感及慢光等领域的应用提供理论参考。

关键词：全介质超表面连续体束缚态准偶然连续体束缚态折射率传感慢光

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

宫颈癌患者肠道微生物的精准检测分析

引用

广西医科大学学报 2024年第3期41卷 444-453页

作者：鲍丽伊王健理李状刘乃榕杜佳园苏金秋李妍余耀杰王鹤广西医科大学附属肿瘤医院妇科南宁530021 广西区域性高发肿瘤早期防治研究重点实验室南宁530021

目的:通过肠道菌群检测了解宫颈癌患者肠道菌群的构成及多样性等特征,以期从肠道菌群方面找出与宫颈癌发生和进展相关预警因子。方法:选取2022年1月至2023年7月在广西医科大学附属肿瘤医院经病理组织学证实且在取材时未接受任何治疗的... 详细信息

目的:通过肠道菌群检测了解宫颈癌患者肠道菌群的构成及多样性等特征,以期从肠道菌群方面找出与宫颈癌发生和进展相关预警因子。方法:选取2022年1月至2023年7月在广西医科大学附属肿瘤医院经病理组织学证实且在取材时未接受任何治疗的正常和宫颈癌患者;通过肠道菌群检测分析相关因素与宫颈癌发生和进展之间的相关性。结果:收集30例健康妇女(正常对照组)和51例宫颈癌患者(宫颈癌组)的大便进行肠道菌群检测;α、β多样性分析显示本次抽样充分,两样本在多样性具有显著差异;与正常对照组比较,宫颈癌组肠道菌群中的菌群多样性明显减少(P0.05)。此外,在对两组的肠道菌群中主要代谢产物和微量元素的比较发现,宫颈癌组肠道菌群中的氨基酸含量均有不同程度的升高、维生素中A、B1、B2、B6、B12、叶酸、维生素C、维生素E、维生素K的含量均显著升高(P<0.05)、微量元素中铁含量降低(P<0.05)、脂肪酸中乙酸含量降低、丁酸含量增多(P<0.05)、营养评估中的脂肪含量降低、碳水化合物含量升高(P<0.05)。结论:宫颈癌患者肠道菌群失调,各种营养素失衡,这些改变可能促进宫颈癌的发生。

关键词：宫颈癌肠道菌群厚壁菌门

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

外泌体分离和纯化方法研究进展

引用

中华检验医学杂志 2021年第2期44卷 167-170页

作者：王耀杰颜晰赵立波赵连梅河北医科大学第四医院科研中心石家庄050011 河北医科大学第四医院检验科石家庄050011 中国科学院化学研究所北京100000

外泌体是由活细胞主动分泌的一种纳米级囊泡,内含蛋白质、核酸等生物活性物质,参与细胞间通讯,在肿瘤微环境调节、免疫识别、炎症反应等众多生理病理过程中发挥重要作用。作为一种运输载体,外泌体广泛存在于生物流体中,但由于其粒径小... 详细信息

外泌体是由活细胞主动分泌的一种纳米级囊泡,内含蛋白质、核酸等生物活性物质,参与细胞间通讯,在肿瘤微环境调节、免疫识别、炎症反应等众多生理病理过程中发挥重要作用。作为一种运输载体,外泌体广泛存在于生物流体中,但由于其粒径小、内含物丰度低,能否获得高质量的外泌体成为后续研究成败的关键。虽然外泌体分离、纯化和鉴定方法日趋发展,但仍未达到成熟水平。本文就外泌体分离和纯化方法的研究进行综述,并比较不同方法的优缺点、适用范围及应用前景,以期为外泌体研究提供参考。

关键词：外泌体分离离心沉淀超滤

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

聚乙二醇干扰素治疗慢性乙型肝炎致1型糖尿病1例报告

引用

临床肝胆病杂志 2021年第8期37卷 1905-1906页

作者：张婷婷赵珏杨彦康姚洁王煊解放军总医院第五医学中心内分泌科北京100039 第九五九六八部队医院内科北京100195

1病例资料患者男性,33岁,因“口干,多饮多尿1周”就诊于解放军总医院第五医学中心内分泌科。于1998年7月中旬查体发现HBsAg、HBeAg、抗HBc阳性,肝功能正常,无乏力、纳差、腹胀等不适,未予治疗。此后定期复查肝功能基本正常。无糖尿病家... 详细信息

1病例资料患者男性,33岁,因“口干,多饮多尿1周”就诊于解放军总医院第五医学中心内分泌科。于1998年7月中旬查体发现HBsAg、HBeAg、抗HBc阳性,肝功能正常,无乏力、纳差、腹胀等不适,未予治疗。此后定期复查肝功能基本正常。无糖尿病家族史。2009年9月于本院门诊查肝功能:ALT 195 U/L,AST 210 U/L,余正常。HBV DNA 2.549×10^(8)IU/ml。

关键词：乙型肝炎,慢性干扰素类糖尿病,1型

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

AaWRKY17, a positive regulator of artemisinin biosynthesis, is involved in resistance to Pseudomonas syringae in Artemisia annua

引用

Horticulture Research 2021年第1期8卷 2926-2936页

作者： Tiantian Chen Yongpeng Li Lihui Xie Xiaolong Hao Hang Liu Wei Qin Chen Wang Xin yan Kuanyu Wu-Zhang Xinghao Yao Bowen Peng yaojie Zhang Xueqing Fu Ling Li Kexuan Tang Joint International Research Laboratory of Metabolic and Developmental Sciences Frontiers Science Center for Transformative MoleculesPlant Biotechnology Research CenterFudan-SJTU-Nottingham Plant Biotechnology R&D CenterSchool of Agriculture and BiologyShanghai Jiao Tong UniversityShanghai 200240China Laboratory of Medicinal Plant Biotechnology College of PharmacyZhejiang Chinese Medical UniversityHangzhou 310053China

Artemisia annua,a traditional Chinese medicinal plant,remains the only plant source for artemisinin production,yet few genes have been identified to be involved in both the response to biotic stresses,such as pathogens,and artemisinin ***,we isolated and identified the WRKY transcription factor(TF)AaWRKY17,which could significantly increase the artemisinin content and resistance to Pseudomonas syringae in *** one-hybrid(Y1H),dual-luciferase(dual-LUC),and electrophoretic mobility shift assay(EMSA)results showed that AaWRKY17 directly bound to the W-box motifs in the promoter region of the artemisinin biosynthetic pathway gene amorpha-4,11-diene synthase(ADS)and promoted its ***-time quantitative PCR(RT-qPCR)analysis revealed that the transcript levels of two defense marker genes,Pathogenesis-Related 5(PR5)and NDR1/HIN1-LIKE 10(NHL10),were greatly increased in AaWRKY17-overexpressing transgenic *** ***,overexpression of AaWRKY17 in *** resulted in decreased susceptibility to *** results indicated that AaWRKY17 acted as a positive regulator in response to *** ***,our findings demonstrated that the novel WRKY transcription factor AaWRKY17 could potentially be used in transgenic breeding to improve the content of artemisinin and pathogen tolerance in ***.

关键词： expression AaW resistance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：