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《清代冕宁司法档案全编》俗语词考释五则

新余学院学报 2024年第1期29卷 40-45页

作者：杨小平宋城林西华师范大学文学院四川南充637009

《清代冕宁司法档案全编》是记载西南少数民族地区民族纠纷通过司法审判的最早档案,极具民族性。档案中俗语词丰富,其中出现了“承缉”“逗逼”“飞覆”“越日”“争角”等俗语词,令人费解。结合辞书、传世文献及语境,“承缉”即“承担... 详细信息

《清代冕宁司法档案全编》是记载西南少数民族地区民族纠纷通过司法审判的最早档案,极具民族性。档案中俗语词丰富,其中出现了“承缉”“逗逼”“飞覆”“越日”“争角”等俗语词,令人费解。结合辞书、传世文献及语境,“承缉”即“承担抓捕”,“逗逼”即“逗留,耽搁”,“飞覆”即“迅速回复”,“越日”即“跨过一日,次日;隔天”,“争角”即“争执、吵架”。

关键词：《清代冕宁司法档案全编》俗语词考释

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政策工具视角下地方性学前教育法规研究

黑龙江教师发展学院学报 2024年第9期43卷 140-145页

作者：王鹏宁杨晓萍西南大学教育学部重庆400715

推进学前教育高质量发展是目前学前教育事业的重点之一,而高质量发展离不开法规的支持。以地方现行有效的20部法规为研究对象,通过对政策工具与政策内容的交叉分析发现,目前法规内容可操作性不强、政策工具尚可优化、法规内容同质化明... 详细信息

推进学前教育高质量发展是目前学前教育事业的重点之一,而高质量发展离不开法规的支持。以地方现行有效的20部法规为研究对象,通过对政策工具与政策内容的交叉分析发现,目前法规内容可操作性不强、政策工具尚可优化、法规内容同质化明显。因此,要细化法规内容,增强可操作性;增强政策工具的多元性和灵活性;突出法规的特色性,避免同质化。

关键词：学前教育地方性法规政策工具

Human Sulfatase-1 Improves the Effectiveness of Cytosine Deaminase Suicide Gene Therapy with 5-Fluorocytosine Treatment on Hepatocellular Carcinoma Cell Line HepG2 In Vitro and In Vivo

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Chinese Medical Journal 2015年第10期128卷 1384-1390页

作者： xiao-ping yang Ling Liu ping Wang Sheng-Lin Ma Department of General Surgery Hangzhou First People's Hospital Hangzhou Hospital Affiliated to Nanjing Medical University Hangzhou Zhejiang 310006 China

Background：Human sulfatase-1 （Hsulf-l） is an endosulfatase that selectively removes sulfate groups from heparan sulfate proteoglycans （HSPGs）,altering the binding of several growth factors and cytokines to HSPG to regulate cell proliferation,cell motility,and *** investigated the role of combined cancer gene therapy with Hsulf-l and cytosine deaminase/5-fluorocytosine （CD/5-FC） suicide gene on a hepatocellular carcinoma （HCC） cell line,HepG2,in vitro and in ***：Reverse transcription polymerase chain reaction and immunohistochemistry were used to determine the expression of Hsulf-1 in *** apoptosis was observed through flow cytometry instrument and mechanism of Hsulf-1 to enhance the cytotoxicity of 5-FC against HCC was analyzed in HCC by confocal *** also establish a nude mice model of HCC to address the effect of Hsulf-1 expression on the CD/5-FC suicide gene therapy in ***：A significant decrease in HepG2 cell proliferation and an increase in HepG2 cell apoptosis were observed when Hsulf-1 expression was combined with the CD/5-FC gene suicide system.A noticeable bystander effect was observed when the Hsulf-1 and CD genes were *** calcium was also increased after HepG2 cells were infected with the Hsulf-1 *** vivo studies showed that the suppression of tumor growth was more pronounced in animals treated with the Hsulf-1 plus CD than those treated with either gene therapy alone,and the combined treatment resulted in a significant increase in ***：Hsulf-1 expression combined with the CD/5-FC gene suicide system could be an effective treatment approach for HCC.

关键词： Cytosine Deaminase/5-Fluorocytosine Suicide System Hepatocellular Carcinoma Human Sulfatase-1

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基于智能优化算法的边坡稳定性预测方法研究

水电能源科学 2024年第5期42卷 96-100页

作者：杨小平段生锐蒋力刘光辉桂林理工大学信息科学与工程学院广西桂林541004 桂林理工大学广西嵌入式技术与智能系统重点实验室广西桂林541004 广西壮族自治区地质环境监测站广西南宁530029 桂林赛普电子科技有限公司广西桂林541004

针对边坡稳定性预测中数据分析片面、模型预测精度低的问题,基于302个边坡案例,选取6个变量特征,利用麻雀搜索算法(SSA)更新BP神经网络的敏感因子,建立SSA-BP边坡稳定性预测模型。采用混淆矩阵、受试者工作特征(ROC)曲线及曲线下面积A_(... 详细信息

针对边坡稳定性预测中数据分析片面、模型预测精度低的问题,基于302个边坡案例,选取6个变量特征,利用麻雀搜索算法(SSA)更新BP神经网络的敏感因子,建立SSA-BP边坡稳定性预测模型。采用混淆矩阵、受试者工作特征(ROC)曲线及曲线下面积A_(UC)值作为衡量指标,通过五折交叉验证法提高模型的泛化能力并与RF、BP、SVM、PSO-BP、GA-BP和LSTM 6种机器学习算法进行预测效果对比。结果表明,SSA-BP模型的A_(UC)值、准确率和F_1分数均最高,分别为91.90%、85.81%和85.87%,相较于优化前的BP网络A_(UC)值提高了23%。经典算例证明SSA-BP预测模型与ABAQUS计算的安全系数相近,并可给出可靠的预测结果,为岩土工程中边坡稳定性预测提供了一种新方法。

关键词：边坡稳定性预测机器学习麻雀搜索算法(SSA) BP网络混淆矩阵

基于机器学习算法的滑坡土壤含水率预测方法研究

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水电能源科学 2024年第3期42卷 73-77页

土壤含水率是影响坡体稳定性的决定因素之一。针对滑坡体内部土壤水分信息难以准确感知的问题,建立了一种基于机器学习算法树突神经网络的土壤含水率预测模型(DDNN),通过分析土壤水分垂向变化特征和数据相关性确定关键的影响因子后,将... 详细信息

土壤含水率是影响坡体稳定性的决定因素之一。针对滑坡体内部土壤水分信息难以准确感知的问题,建立了一种基于机器学习算法树突神经网络的土壤含水率预测模型(DDNN),通过分析土壤水分垂向变化特征和数据相关性确定关键的影响因子后,将水分预测模型DDNN与GA-BP、RF、RBFNN三种算法进行对比试验。发现DDNN预测模型的拟合优度R2最高为0.998,均方根误差和平均绝对误差均最小,分别为0.091、0.059,其预测精度明显高于其他三种算法。并采用关系谱探究了相关影响因素对土壤含水率的敏感程度。结果表明,敏感度由高到低依次为气温、降水、初始水分、风速、地温,研究结果可为滑坡体稳定性分析提供技术方法支撑。

关键词：机器学习算法树突神经网络滑坡体土壤含水率预测相关性敏感性

校园欺凌与情绪调节自我效能感及学校适应的调查研究

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贵州师范学院学报 2024年第6期40卷 35-42页

作者：许秀芬罗浪杨晓平遵义师范学院教师教育学院贵州遵义563006

为探讨青少年校园欺凌中被欺负者与情绪调节自我效能感和学校适应的关系,采用欺负行为问卷、情绪调节自我效能感问卷和学校适应问卷对2830名青少年进行了调查。结果显示:被欺负存在年级(χ^(2)=52.13,p<0.01)和生源地(χ^(2)=97.94,p<0.... 详细信息

为探讨青少年校园欺凌中被欺负者与情绪调节自我效能感和学校适应的关系,采用欺负行为问卷、情绪调节自我效能感问卷和学校适应问卷对2830名青少年进行了调查。结果显示:被欺负存在年级(χ^(2)=52.13,p<0.01)和生源地(χ^(2)=97.94,p<0.01)上的差异;被欺负者的情绪调节自我效能感和学校适应得分显著低于未被欺负者;表达积极情绪(β=0.03,p=0.02)、调节生气/愤怒情绪(β=0.03,p=0.02)和被欺负者的同伴关系(β=0.09,p<0.01)、常规适应(β=0.04,p=0.01)相关显著。这说明,青少年卷入校园欺凌概率、情绪调节自我效能感及学校适应显著相关。

关键词：青少年校园欺凌情绪调节自我效能感学校适应

Flexibility Analysis of Bacillus thuringiensis Cry1Aa

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Biomedical and Environmental Sciences 2015年第9期28卷 634-641页

作者： ZHAO Xin Min XIA Li Qiu yang xiao ping PENG xiao Yun Department of Chemistry and Environmental Engineering Hunan City University Key Laboratory of Microbial Molecular Biology of Hunan Province College of Life ScienceHunan Normal University Division of Medical Oncology Department of MedicineSchool of MedicineUniversity of Colorado Anschutz Medical Campus

Objective To investigate the flexibility and mobility of the Bacillus thuringiensis toxin Cry1 Aa. Methods The graph theory-based program Constraint Network Analysis and normal mode-based program NMsim were used to analyze the global and local flexibility indices as well as the fluctuation of individual residues in detail. Results The decrease in Cry1 Aa network rigidity with the increase of temperature was evident. Two phase transition points in which the Cry1 Aa structure lost rigidity during the thermal simulation were identified. Two rigid clusters were found in domains I and II. Weak spots were found in C-terminal domain III. Several flexible regions were found in all three domains; the largest residue fluctuation was present in the apical loop2 of domain II. Conclusion Although several flexible regions could be found in all the three domains, the most flexible regions were in the apical loops of domain II.

关键词： Flexibility Cry1Aa Bacillus thuringiensis Constraint Network Analysis NMSim

Enhanced expression of epidermal growth factor receptor gene in gastric mucosal cells by the serum derived from rats treated with electroacupuncture at stomach meridian acupoints

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World Journal of Gastroenterology 2006年第34期12卷 5557-5561页

作者： Zong-Bao yang Jie Yan xiao-ping Zou Shou-Xiang Yi xiao-Rong Chang Ya-ping Lin Xi-ping Li College of Acupuncture and Moxibustion Hunan University of Traditional Chinese Medicine Changsha 410007 Hunan Province China

AIM: To investigate the effect of serum derived from rats treated with electroacupuncture at stomach meridian acupoints on the expression of epidermal growth factor receptor (EGFR) gene in gastric mucosal cells. METHODS: The stress-induced gastric mucosal injury in rat model was established by water-immersion and restrained stress methods. 52 rats were randomly divided into: normal group (n = 8), model group (n = 8), model serum group (n = 12), stomach serum group (n = 12), and gallbladder serum group (n = 12). The gastric mucosal cells were separated by pronase-EDTA digestion method and incubated with serum. The EGFR gene expression in gastric mucosal cells was detected by reverse transcription-polymerase chain reaction (RT-PCR) method. RESULTS: Compared with normal group (0.6860 ± 0.0594), the serum derived from rats of the stomach group (1.2272 ± 0.0813, P = 0.00 0.05) and in model serum group (0.8516 ± 0.0409) with an extremely obvious difference (P = 0.001 < 0.01). Furthermore, the EGFR gene expression in stomach serum group was significantly higher than that in gallbladder serum group (P = 0.00 < 0.01). CONCLUSION: The present study shows that serumderived from rats treated with electroacupuncture at stomach meridian acupoints can distinctly increase the EGFR gene expression of gastric mucosal cells. Therefore, there is certain meridian specificity in the serum, which could provide a proof for the TCM theory “particular relation between meridian and internal organ”.

关键词： Electroacupuncture Serum Stomach meridian acupoints Gastric mucosal cells Epidermal growth Factor receptor Gene expression

Advances in noble metal-modified g-C3N4 heterostructures toward enhanced photocatalytic redox ability

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International Journal of Minerals, Metallurgy and Materials 2024年第11期31卷 2368-2389页

作者： Zhang, xiao yang, ping Faculty of Chemical Engineering and Technology Cracow University of Technology Krakow Poland School of Material Science & Engineering University of Jinan Jinan China

The photocatalytic activity of catalysts depends on the energy-harvesting ability and the separation or transport of photogenerated carriers. The light absorption capacity of graphitic carbon nitride (g-C3N4)-based composites can be enhanced by adjusting the surface plasmon resonance (SPR) of noble metal nanoparticles (e.g., Cu, Au, and Pd) in the entire visible region. Adjustments can be carried out by varying the nanocomponents of the materials. The SPR of noble metals can enhance the local electromagnetic field and improve interband transition, and resonant energy transfer occurs from plasmonic dipoles to electron–hole pairs via near-field electromagnetic interactions. Thus, noble metals have emerged as relevant nanocomponents for g-C3N4 used in CO2 photoreduction and water splitting. Herein, recent key advances in noble metals (either in single atom, cluster, or nanoparticle forms) and composite photocatalysts based on inorganic or organic nanocomponent-incorporated g-C3N4 nanosheets are systematically discussed, including the applications of these photocatalysts, which exhibit improved photoinduced charge mobility in CO2 photoconversion and H2 production. Issues related to the different types of multi-nanocomponent heterostructures (involving Schottky junctions, Z-/S-scheme heterostructures, noble metals, and additional semiconductor nanocomponents) and the adjustment of dimensionality of heterostructures (by incorporating noble metal nanoplates on g-C3N4 forming 2D/2D heterostructures) are explored. The current prospects and possible challenges of g-C3N4 composite photocatalysts incorporated with noble metals (e.g., Au, Pt, Pd, and Cu), particularly in water splitting, CO2 reduction, pollution degradation, and chemical conversion applications, are summarized.

关键词： g-C3N4 heterostructure noble metal photocatalysis H_(2)generation CO_(2)