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SIMULATION OF OIL-WATER TWO PHASE FLOW AND SEPARATION BEHAVIORS IN COMBINED T JUNCTIONS

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Journal of Hydrodynamics 2012年第6期24卷 848-857页

作者： CHEN Jian-lei HE li-min LUO Xiao-ming BAI Hai-tao WEI Yan-hai College of Pipeline and Civil Engineering China University of Petroleum(East China)

The combined T junctions used for the oil-water separation have the advantages of compactness in structure, consistency in effects and economy in cost. The mixture k- ε turbulence model and the Eulerian multi-fluid model are used to simulate the flow and phase distribution in the combined T junctions. The effects of structural parameters such as the branched pipe interval and height on the flow distribution and the separation behaviors are studied. The results show that the combined T junctions under fixed inlet and outlet boundary conditions form a single hydraulic equilibrium system in which the fluid energy distributes freely till a balance is achieved. The split-flow promotes the separation of the immiscible oil and the water. The separation efficiency increases with the increase of the branched pipe interval and changes slightly with the increase of the branched pipe height. The structural change of the combined T junctions may change the flow direction in the branched pipes. Simulation results can provide some guidance for the design of the combined T junctions as one kind of oil-water separator.

关键词： T junction oil-water separation CFD phase distribution

Therapeutic advances in non-alcoholic fatty liver disease:A microbiota-centered view

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World Journal of Gastroenterology 2020年第16期26卷 1901-1911页

作者： Hui-Ting Chen Hong-li Huang Yong-Qiang li Hao-ming Xu Yong-Jian Zhou Department of Gastroenterology and Hepatology Guangzhou First People's HospitalSchool of MedicineSouth China University of TechnologyGuangzhou 510180Guangdong ProvinceChina Department of Gastroenterology and Hepatology Guangzhou Digestive Disease CenterGuangzhou First People’s HospitalGuangzhou Medical UniversityGuangzhou 510180Guangdong ProvinceChina

Non-alcoholic fatty liver disease(NAFLD)is a highly prevalent metabolic disorder with steadily increasing incidence rates worldwide,especially in the *** are no drugs available at present to treat NAFLD,and the primary therapeutic options include weight loss and the combination of healthy diet and ***,novel interventions are required that can target the underlying risk *** microbiota is an“invisible organ”of the human body and vital for normal metabolism and *** number and diversity of microbes differ across the gastrointestinal tract from the mouth to the anus,and is most abundant in the *** dysregulated gut microbiota is an underlying pathological factor of NAFLD,it is a viable therapeutic target that can be modulated by antibiotics,probiotics,prebiotics,synbiotics,fecal microbiota transplantation,and microbial *** this review,we summarize the most recent advances in gut microbiota-targeted therapies against NAFLD in clinical and experimental studies,and critically evaluate novel targets and strategies for treating NAFLD.

关键词： Non-alcoholic fatty liver disease Gut microbiota Probiotics Prebiotics Fecal microbiota transplantation Metabolites

Transcriptomic responses to aluminum(Al)stress in maize

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Journal of Integrative Agriculture 2018年第9期17卷 1946-1958页

作者： XU li-ming liU Chan CUI Bao-ming WANG Ning ZHAO Zhuo ZHOU li-na HUANG Kai-feng DING Jian-zhou DU Han-mei JIANG Wei ZHANG Su-zhi Key Laboratory of Biology and Genetic Improvement of Maize in Southwest China Ministry of Agriculture/Maize Research InstituteSichuan Agricultural UniversityChengdu 611130P.R.China Crop Research Institute of Binzhou Binzhou 256600P.R.China

Aluminum （AI） toxicity is a major factor limiting crop production and plant growth in acid soils. The complex inheritance of AI toxicity and tolerance mechanisms in maize has uncharacterized yet. In this study, the maize inbred line 178 seedlings were treated with 200 μmol L-1 CaCI2＋0 μmol L^-1AICI3 （control） and 200μmol L^-1 CACI2＋60 IJmol L^-1 AICI3 （AI treatment） for I and 6 h, respectively. The experiment was repeated three times. Then a detailed temporal analysis of root gene expression was performed using an Agilent GeneChip with 34 715 genes, only the genes showing more than 2.0-fold difference （P〈0.01） between the control and the AI treatment maize seedlings were analyzed further. Thus, a total of 832 different expression genes, 689 significantly up-regulated and 143 down-regulated, were identified after the seedlings were treated with AI for 6 h. And 60 genes, 59 up-regulated and one down-regulated, were also detected after the seedlings were treated for 1 h. Replicated transcriptome analyses further showed that about 61% of total significantly genes could be annotated based on plant genome resources. Quantitative real-time PCR （qRT-PCT） of some selected candidate genes was used to demonstrate the microarray data, indicating significant differences between the control and AI-treated seedlings. Exposure to AI for 6 h triggered changes in the transcript levels for several genes, which were primarily related to cell wall structure and metabolism, oxidative stress response, membrane transporters, organic acid metabolism, signaling and hormones, and transcription factors, etc. After AI-treated for 1 h, differential abundance of transcripts for several transporters, kinase, and transcription factors were specifically induced. In this study, the diversity of the putative functions of these genes indicates that AI stress for a short stage induced a complex transcriptome changes in maize. These results would further help us to understand rapid and early mechanisms o

关键词： aluminum maize microarray mechanism transcriptome

Mechanical property and thermal shock behavior of tungsten-yttria-stabilized zirconia cermet fabricated by spark plasma sintering

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Tungsten 2024年第1期6卷 134-140页

作者： lin-Chao Zhang Ke Jing Rui liu Zhuo-ming Xie Jun-Feng yang Gang li Xian-Ping Wang Xue-Bang Wu Qian-Feng Fang Chang-Song liu Key Laboratory of Materials Physics Institute of Solid State PhysicsHFIPSChinese Academy of SciencesHefei 230031China University of Science and Technology of China Hefei 230026China Science and Technology on Reactor Fuel and Materials Laboratory Nuclear Power Institute of ChinaChengdu 610041China

The cermet fuels have been considered as a potential key component for the nuclear thermal propulsion,and the homogeneity of the fuel particles in the metal matrix plays a crucial role in stabilizing the structure at extremely high *** this work,liquid paraffin was used as additive to improve the distribution of yttria-stabilized zirconia(YSZ,an appropriate surrogate for UO_(2) fuel)microspheres in the tungsten(W)matrix,and the W-YSZ cermet wafers(volume ratio 1:1)with a relative density of 97.6%were fabricated by spark plasma sintering with a specifically designed *** effects of the paraffin dosage(0-5 wt.%)on the homogeneity,microstructure,mechanical properties,and the thermal conductivity of W-YSZ cermet were *** W-YSZ sample with 2 wt.%paraffin shows the highest homogeneity and exhibits the best comprehensive properties,including the ultimate tensile strength of 132.2 MPa at 600℃,the bending strength of455 MPa and thermal conductivity of 50 W·m^(-1)·K^(-1)at room ***,the cermet could keep structurally sound after thermal shocked at a heat load of 20 MW·m^(-2).These results would be helpful for the design and optimization of the cermet fuels in the nuclear thermal propulsion.

关键词： Nuclear thermal propulsion Tungsten Cermet liquid paraffin Thermal shock

Pearprocess:A new phenotypic tool for stone cell trait evaluation in pear fruit

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Journal of Integrative Agriculture 2020年第6期19卷 1625-1634页

作者： XUE Yong-song XU Shao-zhuo XUE Cheng WANG Run-ze ZHANG ming-yue li Jia-ming ZHANG Shao-ling WU Jun Center of Pear Engineering Technology Research State Key Laboratory of Crop Genetics and Germplasm EnhancementNanjing Agricultural UniversityNanjing 210095P.R.China

The content of stone cells is an important factor for pear breeding as a high content indicates severely reduced fruit quality in terms of fruit *** the frozen-HCI method is currently a common method used to evaluate stone cell content in pears,it is limited in incomplete separation of stone cell and pulp and is time consuming and *** research is a promising strategy in modern scientific research for phenotypic data collect!on and is increasingly used in studying *** far,we lack a quantitative tool that can effectively determine stone cell content in pear *** developed a program,Pearprocess,based on an imaging protocol using computer vision and image processing algorithms applied to digital *** photos of hand-cut sections of pear fruit stained with phloroglucin-HCI(Wiesner's reagent),Pearprocess can extract and analyze image-based data to quantify the stone cell-related traits measured in this study:number,size,area and density of stone *** quantified these traits for 395 pear accessions by Pearprocess and revealed large variation in different pear varieties and *** number of stone cells varied greatly from value of 138 to 2866,the density of stone cells ranged from 0.0019 to 0.0632 cm2 cm-2,the distribution of stone cell area ranged from 0.06 to 2.02 cm2,and the stone cell size was between 2e-4 and 1e-3 ***,trait data were correlated with fruit taste *** found that stone cell density is likely the most important factor affecting the taste of pear *** summary,Pearprocess is a new cost-effective web-application for semi-automated quantification of two-dimensional phenotypic traits from digital imagery using an easy imaging *** simpler,feasible and accurate method to evaluate stone cell traits of fruit is a promising new tool for use in evaluating future germplasms for crop breeding programs.

关键词： Pearprocess software quantitative tool stone cell traits

Distribution of IOP and its relationship with refractive error and other factors:the Anyang University Students Eye Study

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International Journal of Ophthalmology(English edition) 2021年第4期14卷 554-559页

作者： Dandan Ma Shifei Wei Yunyun Sun Shi-ming li Wen-Zai An Jian-Ping Hu Kai Cao Xiao-Hui yang Cai-Xia lin Ji-Yuan Guo He li Jing Fu Ningli Wang Beijing Tongren Eye Center Beijing Tongren HospitalBeijing Ophthalmology&Visual Sciences Key LaboratoryBeijing Institute of OphthalmologyCapital Medical UniversityBeijing 100730China Beijing Institute of Ophthalmology Beijing 100730China Anyang Eye Hospital Anyang 455000Henan ProvinceChina

AIM:To investigate the distribution of intraocular pressure(IOP)and its relationship with refractive error and other factors in university students from Anyang,***:A university-based study was *** were invited to complete ophthalmic examinations,including visual acuity,noncontact tonometr y(NCT),cycloplegic autorefraction,and ocular *** and multivariable analyses were used to evaluate the associations between IOP and other *** data from right eyes were used in ***:A total of 7720 subjects aged 16 to 26 years old were included,and 2834(36.4%)of the participants were *** mean IOP of the right eye for all subjects was 15.52±3.20 mm Hg(95%CI:15.45,15.59).Using multivariate linear regression analysis,IOP was found to correlate significantly with younger age(P<0.001;standardized regression coefficientβ,-0.061;regression coefficientβ,-0.139;95%CI:-0.18,-0.09),higher myopic refractive error(P=0.044;standardizedβ,-0.060;regression coefficientβ,-0.770;95%CI:-0.15,-0.002),higher central corneal thickness(P<0.001;standardizedβ,0.450;regression coefficientβ,0.044;95%CI:0.04,0.05),and shorter axial length(AL;P<0.001;standardizedβ,-0.061;regression coefficientβ,-0.163;95%CI:-0.25,-0.07).CONCLUSION:This study described the normal distribution of *** Chinese university students aged 16-26 y,higherIOP is associated with younger age,higher myopic refractive error,higher thickness of the central cornea,and shorter AL.

关键词： intraocular pressure refractive errors epidemiology university students

Quaternary ammonium-induced multidrug tolerant Streptococcus mutans persisters elevate cariogenic virulence in vitro

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International Journal of Oral Science 2017年第4期9卷 224-231页

作者： Ya-ling Jiang Wei Qiu Xue-Dong Zhou Hao li Jun-Zhuo Lu Hockin HK Xu Xian Peng ming-Yun li ming-Ye Feng Lei Cheng Biao Ren State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases&Department of Operative Dentistry and Endodontics West China Hospital of StomatologySichuan UniversityChengduChina Biomaterials&Tissue Engineering Division Department of EndodonticsProsthodontics and Operative DentistryUniversity of Maryland Dental SchoolBaltimoreUSA

Dental caries are the most prevalent chronic infections in the oral cavity, and Streptococcus mutans acts as the main cariogenic bacterial species. Antibacterial quaternary ammonium compounds （QAs） have been developed to preveFnt or treat dental caries. However, there is no report on the tolerance of S. mutans to QAs. In this study, we investigated the development of S. mutans persistence induced by a novel dental caries defensive agent, dimethylaminododecyl methacrylate （DMADDM）, for the first time. Typical biphasic killing kinetics for persisters were observed in both S. mutans planktonic and biofilm cultures challenged by DMADDM at concentrations of 20 and 200 ***- z respectively. The persisters tolerated six other antibiotics with different antibacterial mechanisms, while only daptomycin and vancomycin could slightly reduce the persister numbers in planktonic cultures. The distribution of persisters in DMADDM-treated biofilms was similar to that in the untreated control, except that the total biomass and biofilm height were significantly reduced. A higher exopolysaccharides （EPS）：bacteria ratio was observed in DMADDM-treated biofilms. Persisters in biofilms significantly upregulated gtf gene expression, indicating an increase in the bacteria＇s ability to produce EPS and an elevated capability of cariogenic virulence. Carbon source metabolism was significantly reduced, as related metabolic genes were all downregulated in persisters. Concentrations of 0.1 mM, 1 mM and 10 mM of extra glucose significantly reduced the number of persisters both in planktonic and biofilm conditions. The formation of non- inheritable and multidrug tolerant persisters induced by DMADDM suggested that drug tolerance and new persistent eradication strategies should be considered for oral antibacterial agents.

关键词： antibacterial quaternary ammoniums dental caries persistence multidrug tolerance Streptococcus mutans biofilms

Laboratory-scale study of the suppression of PCDD/F emission during coal and MSW co-incineration

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Journal of Environmental Sciences 2007年第6期19卷 762-767页

作者： LU Sheng-yong YAN Jian-hua li Xiao-dong NI ming-jiang CEN Ke-fa State Key Laboratory of Clean Energy Utilization Institute for Thermal Power Engineering Zhejiang University Hangzhou 310027 China

The experimental test of co-incinerating Chinese raw municipal solid waste （MSW） and coal in a laboratory-scale tubular reactor was first reported in present study, and the emission of normal gas components and the effects of the S/Cl molar ratio or coal mixing percentages on polychlorinated dibenzo-p-dioxins and dibenzofurans （PCDDs/Fs） emission were investigated and discussed. The results indicated that OCDD was the only PCDD homologues since others like TCDD-HpCDD was hardly detected, while as the categories of PCDF homologues were comparatively much more general. The amount of PCDD was much larger than that of PCDF in all operating conditions. Since ZPCDF/∑PCDD〈〈1, the dominant role of the precursor formation was proven in our experimental conductions. With increasing the coal addition to MSW （from 0 to 16%）, PCDD and PCDF were reduced considerably. Coal and MSW may suppress the PCDD/F emissions efficiently （over 95%） during the MSW incineration process. The PCDD/F suppression results of the present study could be helpful guidance to the industrial application of Chinese MSW and auxiliary coal co-incineration processes. The PCDD/F stack emission data of two industrial incinerators using co-incineration technology in China seem to have a great positive reduction of PCDDs/Fs.

关键词： co-incineration PCDDs/Fs suppression S/Cl molar ratio

Technology of fiber-optic temperature sensing and its application in ＆ temperature measuring of gob area

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Journal of Coal Science & Engineering(China) 2011年第2期17卷 171-175页

作者： liU Jing-wen HUANG li-ming Department of Business Management Heibei Normal University of Science and Technology Qinhuangdao 066004 China

Based on advantages of technology of distributive fiber-optic temperature sensing and specific to its applications in monitoring mine conflagration, the corresponding Processes such as connection arrangement, signal transmission and monitoring were illustrated. As applied in Sitai Coal Mine of Datong Coal Mine Group Co., this method is effective and accurate and could provide reliable gist for monitoring spontaneous combustion in gob area of mines.

关键词： distributive optical fiber gob area temperature sensing fire source detection