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Energy Geoscience 2024年第2期5卷 62-69页

作者： Wenbiao Huang Yibing Guo Jun Qin Zhongchen ba.Zongbin Zhang Luning ba. Heng Li School of Geosciences China University of Petroleum(East China)QingdaoShandong266580China PetroChina Xinjiang Oilfield Company KaramayXinjiang834000China

The intricate distribution of oil and water in tight rocks makes pinpointing oil layers *** conventional identification methods offer potential solutions,their limited accuracy precludes them from being effective in their applications to unconventional *** study employed nuclear magnetic resonance(NMR)spectrum decomposition to dissect the NMR T_(2)spectrum into multiple ***,it employed laboratory NMR experiments to ascertain the fluid properties of these sub-spectra,aiming to enhance identification *** findings indicate that fluids of distinct properties overlap in the T_(2)spectra,with bound water,movable water,bound oil,and movable oil appearing sequentially from the low-value zone to the high-value ***,an oil layer classification scheme was proposed,which considers the physical properties of reservoirs,oil-bearing capacity,and the characteristics of both mobility and the oil-water two-phase *** applied to tight oil layer identification,the scheme's outcomes align closely with actual test results.A horizontal well,deployed ba.ed on these findings,has produced high-yield industrial oil flow,underscoring the precision and dependability of this new approach.

关键词： Nuclear magnetic resonance Fluid identification Oil layer identification NMR T_(2)spectrum decomposition Normal distribution simulation

Cathodic corrosion as a facile and universal method for scalable preparation of powdery single atom electrocatalysts

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Nano Research 2024年第6期17卷 4943-4950页

作者： Rui Li Xiayan Yan Meng Liu Qingkai Zhao Jie Du Xinxin Tan Jingwen ba.Rongguang Zeng Wenhua Luo Jingsong Xu Institute of Materials China Academy of Engineering PhysicsJiangyou 621907China Science and Technology on Surface Physics and Chemistry Laboratory Jiangyou 621908China

Top-down strategy has been widely applied for synthesis of metal single atom catalysts(SACs)via converting metal nanoparticles or bulk metals into atomically dispersed ***,we report a simple electrochemical atomic migration strategy for top-down synthesis of SACs via a facile cathodic corrosion process without involving high temperature or harsh *** of metal nanoparticles on cathode are firstly disba.ded under high negative voltage,and emitted into the electrolyte in the form of atomic metal anions in Zintl *** escaped atomically dispersed metal species are then oxidized by water molecules and captured by the defects on the pre-added nitrogen doped carbon carriers in the *** cathodic corrosion strategy is confirmed to be suitable for scalable synthesis of kinds of metal SACs(e.g.,Pt,Pd,and Ir)on doped carbon ***,the as-prepared nitrogen doped carbon powder supported Pt SACs exhibit superior catalytic activity toward hydrogen evolution reaction(HER)with a low overpotential of 0.024 V at 10 mA·cm^(−2)and a low Tafel slope of 29.7 mV·dec^(−1)as well as a long-term durability.

关键词： cathodic corrosion top-down strategy powdery single atom catalysts hydrogen evolution reaction scalable synthesis

Superior piezoelectric performance with high operating temperature in bismuth ferrite-ba.ed ternary ceramics

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Journal of Materials Science & Technology 2024年第2期169卷 172-181页

作者： Yunyao Huang Leiyang Zhang Ruiyi Jing yang yang Vladimir Shur Xiaoyong Wei Li Jin Electronic Materials Research Laboratory Key Laboratory of the Ministry of EducationSchool of Electronic Science and EngineeringXi’an Jiaotong UniversityXi’an 710049China Faculty of Materials and Manufacturing Key Laboratory of Advanced Functional MaterialsEducation Ministry of ChinaBeijing University of TechnologyBeijing 100124China School of Natural Sciences and Mathematics Ural Federal UniversityEkaterinburg620000Russia

Due to the thermal depolarization effect,adequate piezoelectric performance with high operating temperature is regarded to be challenging to accomplish concurrently in piezoceramics for applications in specific piezoelectric *** this work,we synthesized(0.8−x)BiFeO_(3)-x PbTi_(3)-0.2ba.Zr_(0.25)Ti_(0.75))O_(3)(abbreviated as BFO-x PT-BZT)ternary solid solutions with 0.15≤x≤0.30 by conventional solid-state reaction *** MPB composition with a coexisting state of rhombohedral-tetragonal phases exhibits enhanced electromechanical properties,including Curie temperature of 380℃,large-signal equivalent piezoelectric coefficient d^(∗)_(33)of 395 pm V^(-1),small-signal piezoelectric coefficient d_(33)of 302 pC N^(-1),and electromechanical coupling factor k_(p)of 50.2%,which is comparable to commercial PZT-5A ceramics,indicating potential in high-temperature ***,in-situ X-ray diffraction(XRD)and piezoelectric force microscopic(PFM)techniques demonstrate that multiphase coexistence and complex nanodomains promote piezoelectric response via *** x=0.24 composition exhibits the highest in-situ d_(33)of 577 pC N^(-1)and good temperature stability in 30−280℃,indicating that BZT-modified BFO-PT ceramics are promising candidates for high-temperature piezoelectric devices.

关键词： High-temperature piezoelectrics Morphotropic phase boundary In-situ technique Domain structure BFO

Metabolic syndrome’s new therapy:Supplement the gut microbiome

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World Journal of Diabetes 2024年第4期15卷 793-796页

作者： Yong-Wei Xu Jun Tian Yan Song ba.Cui Zhang Jing Wang Department of Gastroenterology Songjiang HospitalSchool of MedicineShanghai Jiaotong UniversityShanghai 201600China

This letter to the editor discusses the publication on gut microbiome supple-mentation as therapy for metabolic *** microbiome dysbiosis disrupts intestinal ba.terial homeostasis and is related to chronic inflammation,insulin resistance,cardiovascular diseases,type 2 diabetes mellitus,and *** research has found that increasing the abundance of beneficial microbiota in the gut modulates metabolic syndrome by reducing chronic inflammation and insulin ***,probiotics,synbiotics,and postbiotics are often used as supplements to increase the number of beneficial microbes and thus the produc-tion of short-chain fatty acids,which have positive effects on the gut microbiome and metabolic *** this review article,the author summarizes the available supplements to increase the abundance of beneficial gut microbiota and reduce the abundance of harmful microbiota in patients with metabolic *** group is also researching the role of the gut microbiota in chronic liver *** article will be of great help to our *** the end of the letter,the mechanism of the gut microbiota in chronic liver disease is discussed.

关键词： Gut microbiome Metabolic syndrome Diabetes mellitus Short-chain fatty acids Chronic liver disease

A review on covalent organic frameworks for rechargeable zinc-ion ba.teries

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Chinese Chemical Letters 2024年第7期35卷 107-120页

作者： Yunyu Zhao Chuntao yang Yingjian Yu College of Physics Science and Technology Kunming UniversityKunming 650214China

In recent years,rechargeable zinc-ion ba.teries(ZIBs)are considered to be a promising alternative to lithium-ion ba.teries owing to their high safety and theoretical capacity with low ***,the in-depth development of rechargeable zinc-ion ba.teries is restricted by a sequence of issues,such as the dissolution and structure collapse of cathode materials,the formation of by-products,severe anode corrosion,passivation,and the growth of zinc *** covalent organic frameworks(COFs)can solve the above problems to a certain extent owing to their ideal characteristics,such as rigid structure,insolubility,high porosity,and abundant active ***,as advanced materials for ZIBs,have attracted researchers'*** this review,we systematically summarized the synthesis methods of COFs and discussed the application of several advanced characterization technologies in COFs,which would provide a reference for the in-depth research of *** addition,we elucidated the use of COFs as cathode materials and anode protective layers in rechargeable ***,we discussed the challenges and solutions in the development of COF materials,which would provide constructive insights into the future direction of COFs.

关键词： Covalent organic framework Zn-ion ba.tery Zinc dendrite Anode Cathode

Verteporfin fluorescence in antineoplastic-treated pancreatic cancer cells found concentrated in mitochondria

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 968-978页

作者： Ying-Qiao Zhang Qing-Hao Liu Lu Liu Peng-Yu Guo Run-Ze Wang Zhi-Chang ba Department of Radiology Harbin Medical University Cancer HospitalHarbin 150010Heilongjiang ProvinceChina Department of Digestive Internal Medicine Harbin Medical University Cancer HospitalHarbin 150010Heilongjiang ProvinceChina

ba.KGROUND Traditional treatments for pancreatic cancer(PC)are *** therapy(PDT)is non-invasive,and proven safe to kill cancer cells,including ***,the mitochondrial concentration of the photosensitizer,such as verteporfin,is *** To investigate the distribution of fluorescence of verteporfin in PC cells treated with antitumor drugs,*** Workable survival rates of PC cells(AsPC-1,BxPC-3)were determined with chemotherapy[doxorubicin(DOX)and gemcitabine(GEM)]and non-chemotherapy[sirolimus(SRL)and cetuximab(CTX)]drugs in vitro,with or without verteporfin,as measured via MTT,flow cytometry,and laser confocal *** cell proliferation was associated with GEM that was more enduring compared with *** laser microscopy allowed observation of GEM-and verteporfin-treated PC cells co-stained with 4’,6-diamidino-2-phenylindole and MitoTracker Green to differentiate living and dead cells and subcellular localization of verteporfin,*** Cell survival significantly dropped upon exposure to either chemotherapy drug,but not to SRL or *** cell lines responded similarly to *** intensity of fluorescence was associated with the concentration of *** experiments using GEM showed that survival rates of the PC cells treated with 10μmol/L verteporfin(but not less)were significantly lower relative to nil *** and dead stained cells treated with GEM were *** GEM treatment,verteporfin was observed primarily in the *** Verteporfin was observed in living *** GEM-treated human PC cells,verteporfin was particularly prevalent in the *** study supports further study of PDT for the treatment of PC after neoadjuvant chemotherapy.

关键词： Photodynamic therapy Pancreatic cancer Verteporfin Mitochondria Chemotherapy Gemcitabine

The Role of Renewable Protocatechol Acid in Epoxy Coating Modification: Significantly Improved Antiba.terial and Adhesive Properties

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Chinese Journal of Polymer Science 2024年第1期42卷 63-72,I0008页

作者： Ming-Xuan Chen Jin-Yue Dai Li-Yue Zhang Shuai-Peng Wang Jing-Kai Liu Yong-Gang Wu Xin-Wu ba.Xiao-Qing Liu School of Chemistry and Materials Science Hebei UniversityBaoding 071000China Ningbo Institute of Materials Technology and Engineering Chinese Academy of SciencesNingbo 315201China Key Laboratory of Marine Materials and Related Technologies Chinese Academy of SciencesNingbo 315201China

It is of great significance to design epoxy coatings with superior antiba.terial properties and high adhesive properties, as well as excellent processing, superior durability, and high transparency. However, it is still a challenge because of the common complex design and synthesis. Herein, the bio-ba.ed monomer protocatechuic acid(PCA) was used as raw material, the catechol structure with high bonding and antiba.terial properties was introduced into the flexible alkane segment of ethylene glycol diglycidyl ether(EGDE) through an efficient, and green method, and it was cured with isophorone diamine(IPDA) to prepare corresponding thermosets. The cured resins exhibited excellent allaround qualities, particularly in bonding and antiba.terial. When 30% PCA was added to pure epoxy resin, the adhesion between substrate and coating increased from 4.40 MPa to 13.60 MPa and the antiba.terial rate of coating against E. coli and S. aureus could approach 100%. All of this is due to the fact that the catechol structure present in PCA has the ability to interact with various substrates and alter the permeability of ba.terial cell membranes. The architecture of this method offers a fresh approach to dealing with the issues of challenging raw material selection and complex synthesis techniques.

关键词： Epoxy coatings Thermosets Catechol structure Antiba.terial High adhesion

circRNA3669 promotes goat endometrial epithelial cells proliferation via miR-26a/RCN2 to activate PI3K/AKT-mTOR and MAPK pathways

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Journal of Integrative Agriculture 2024年第3期23卷 960-974页

作者： Xiaorui Liu Jiuzeng Cui Mengyao Wei Xiaofei Wang Yuexia Liu Zhongshi Zhu Min Zhou Gui ba.Langda Suo Yuxuan Song Lei Zhang Division of Laboratory Safety and Services Northwest A&F UniversityYangling 712100China College of Animal Science and Technology Northwest A&F UniversityYangling 712100China Institute of Animal Sciences Tibet Academy of Agricultural and Animal Husbandry SciencesLhasa 850009China

The development of receptive endometrium(RE) from pre-receptive endometrium(PE) for successful embryo implantation is a complex dynamic process in which the morphology and physiological states of the endometrial epithelium undergo a series of significant changes, including cell proliferation and apoptosis. However, the molecular mechanisms are not yet fully understood. In this study, a higher circRNA3669 level was observed in PE than in RE of goats. Functional assays revealed that this overexpression promoted the proliferation of goat endometrial epithelial cells(GEECs) by activating the expression of genes related to the PI3K/AKT-mTOR and MAPK pathways,thereby inhibiting apoptosis in vitro. Furthermore, circRNA3669 functioned as a competing endogenous RNA(ceRNA) to upregulate Reticulocalbin-2(RCN2) expression at the post-transcriptional level by interacting with and downregulating miR-26a in GEECs. In addition, RCN2, which is highly expressed in the PE of goats, was found to be regulated by β-estradiol(E2) and progesterone(P4). Our results demonstrated that RCN2 also affected the key proteins PI3K, AKT, mTOR, JNK, and P38 in the PI3K/AKT-mTOR and MAPK pathways, thereby facilitating GEECs proliferation and suppressing their apoptosis in vitro. Collectively, we constructed a new circRNA3669-miR-26aRCN2 regulatory network in GEECs, which further provides strong evidence that circRNA could potentially play a crucial regulatory role in the development of RE in goats.

关键词： circRNA3669 RCN2 miR-26a goat endometrial epithelial cells(GEECs) proliferation

Discovering genetic biomarkers for targeted cancer therapeutics with eXplainable Artificial Intelligence

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Cancer Communications 2024年第5期44卷 584-588页

作者： Deba.itya Chakraborty Elizabeth Gutierrez-Chakraborty Cristian Rodriguez-Aguayo Hakan ba.ağaoğlu Gabriel Lopez-Berestein Paola Amero School of Civil and Environmental Engineering and Construction Management The University of Texas at San AntonioSan AntonioTexasUSA Department of Cell Systems and Anatomy University of Texas Health Science CenterSan AntonioTexasUSA Department of Experimental Therapeutics The University of Texas MD Anderson Cancer CenterHoustonTexasUSA Edwards Aquifer Authority San AntonioTexasUSA

High-Grade Serous Ovarian Cancer(HGSC)is the most prevalent and lethal form of gynecologic malignancies[1],accounting for 70%-80%of ovarian cancer *** decades of research,the overall survival rate for HGSC has remained largely unchanged[2],and patients with advanced stages of the disease have only a 41%chance of surviving beyond five years[3].

关键词： cancer Cancer targeted

Investigation of Fracture Strength of Current Post Materials (Peek, Fiber, Cast Metal) in Different Ferrule Conditions

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Open Journal of Stomatology 2024年第3期14卷 153-172页

作者： ba.ak Topdaği Funda ba.indir Department of Prosthetic Dentistry Atatürk University Erzurum Türkiye

Aim: The fracture resistance of the post materials used nowadays significantly impacts the fracture type of the post material. The current study aimed to examine the impact of the fracture resistance of PEEK posts, whose use as a post material has not yet become widespread, on the fracture pattern that will occur. Materials and Methods: Sixty-six extracted upper central incisor human teeth were used in the study. Six groups of posts were produced from metal, fiber, and PEEK materials (n = 11). Afterward, the fracture resistance test was applied to the samples. Samples were classified according to fracture type as repairable or irreparable. The ANOVA and test were used in statistical analysis. Post-hoc tests were carried out using Tukey’s and Tamhane’s T2 tests. On the other hand, Pearson’s chi-square test and the Fisher-Freeman-Halton test were conducted for comparisons between categorical variables. The statistical significance level was accepted as p Results: According to the fracture resistance test results, the groups where metal personal posts were used displayed higher fracture resistance in comparison with all other groups. According to the results of the optical microscope examination, the incidence of repairable fractures was significantly higher in the PEEK post group with ferrule preparation (p 0.05). Conclusion: In the absence of the ferrule effect, fractures are catastrophic, regardless of the material used. The use of PEEK as a post material contributes to keeping fractures at a repairable level.

关键词： Component Formatting Style Styling Insert