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血清25-(OH)D水平与2型糖尿病患者血糖和胰岛β细胞功能相关性及阿法骨化醇片干预作用

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中国临床研究 2020年第6期33卷 788-791页

作者：郝艳周倩云无锡市太湖医院内分泌科江苏无锡221044

目的探讨血清25羟维生素D[25-(OH)D]水平与2型糖尿病(T2DM)患者血糖、胰岛β细胞功能相关性及阿法骨化醇片干预作用。方法选取2017年11月至2019年3月无锡市太湖医院门诊诊治T2DM患者106例,抽取血液样本测定25-(OH)D水平、糖化血红蛋白(H... 详细信息

目的探讨血清25羟维生素D[25-(OH)D]水平与2型糖尿病(T2DM)患者血糖、胰岛β细胞功能相关性及阿法骨化醇片干预作用。方法选取2017年11月至2019年3月无锡市太湖医院门诊诊治T2DM患者106例,抽取血液样本测定25-(OH)D水平、糖化血红蛋白(HbA1c)、胰岛β细胞功能指数(HOMA-β)、胰岛素抵抗指数(HOMA-IR),统计分析25-(OH)D与HbA1c、HOMA-β、HOMA-IR间关联性,应用简单随机化分组方法分为研究组和对照组,各53例。对照组采取甘精胰岛素联合沙格列汀片,研究组于对照组基础上加用阿法骨化醇片,均治疗2个月。比较两组治疗前后血糖[HbA1c、空腹血糖(FPG)、餐后2 h血糖(2hPG)]、胰岛β功能指标(HOMA-β、HOMA-IR)、25-(OH)D水平、不良反应。结果25-(OH)D水平与HbA1c、HOMA-IR存在显著负相关,与HOMA-β存在明显正相关(P0.05)。结论25-(OH)D水平与T2DM患者HbA1c、HOMA-IR存在负相关,与HOMA-β存在正相关,阿法骨化醇片可提高患者机体维生素D水平,改善患者血糖水平、胰岛β细胞功能,且安全可靠。

关键词： 25羟维生素D 2型糖尿病糖化血红蛋白胰岛β细胞功能指数胰岛素抵抗指数阿法骨化醇

Two modes of biofilm formation by Bacillus cereus 905

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Two modes of biofilm formation by Bacillus cereus 905

机匣与叶顶蜂窝密封对涡轮叶栅顶部泄漏流动的影响

中国植物病理学会2015年学术年会

作者： GAO Tan-tan LUCY Foulston CHAI yun-rong RICHARD Losick LI yan WANG Qi Department of Plant Pathology China Agricultural University Department of Molecular and Cellular Biology Harvard University Department of Biology Northeastern University

The ability to form multicellular communities known as biofilms is a widespread adaptive behavior of *** of the Bacillus group of bacteria have been found to form biofilms on plant roots,where they protect against pathogens and promote *** the case of the model bacterium Bacillus subtilis,the genetic pathway controlling biofilm formation and the production of an extracellular matrix is relatively well ***,it is unclear whether other members of this genus utilize similar *** 905,isolated from the roots of the wheat,is a plant-associated strain with function of promoting the growth of the *** determined that it could form biofilms by two seemingly independent *** one mode,the floating biofilms（pellicles） formationof *** appeared to rely on orthologs of many of the genes known to be important for *** biofilm *** the second mode,we reported that *** 905 formed submerged,surface-associated biofilms and in a manner that resembled biofilm formation by the pathogen Staphylococcus *** alternative mode,which did not rely on ***-like genes for pellicle formation,took place under conditions of glucose fermentation and depended on a decrease in the pH of the *** two modes of behavior appeared to be achieved in radically different ways and were likely operating under different environmental *** principal contribution of this investigation is the discovery that a plant-root-associated strain ***（905） could form two kinds of biofilms that are produced by two seemingly unrelated *** toto,our genetic analysis of *** biofilm formation sheds light on how a similar outcome,biofilm formation,can be achieved in different ways and this maybe provide an evidence of that *** can survive ubiquitously in the complicated environment.

关键词： Bacillus cereus biofilm pellicle

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工程热物理学报 2016年第5期37卷 963-968页

作者：付云峰宋彦萍陈聪陈浮哈尔滨工业大学能源科学与工程学院哈尔滨150001

本文采用数值计算方法研究了机匣蜂窝和叶顶蜂窝对涡轮叶栅动叶顶部间隙泄漏流动特性及其损失产生和分布的影响。结果表明:相比于常规无蜂窝密封的叶栅,机匣蜂窝和叶顶蜂窝在间隙泄漏流动的抑制方面都有积极的效果,相对间隙泄漏量分别... 详细信息

本文采用数值计算方法研究了机匣蜂窝和叶顶蜂窝对涡轮叶栅动叶顶部间隙泄漏流动特性及其损失产生和分布的影响。结果表明:相比于常规无蜂窝密封的叶栅,机匣蜂窝和叶顶蜂窝在间隙泄漏流动的抑制方面都有积极的效果,相对间隙泄漏量分别降低了52%和8.2%;由于机匣蜂窝与主流的接触面积较大带来额外损失,使得涡轮叶栅出口损失增加了约2.66%,而叶顶蜂窝内叶栅出口损失减少了1.87%。

关键词：涡轮间隙泄漏流动叶顶蜂窝机匣蜂窝

Non-lens betagamma-crystallin and Trefoil factor Complex triggers innate immunity by activating NLRP3 inflammasome

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Non-lens betagamma-crystallin and Trefoil factor Complex tri...

Flexural behaviors of double-reinforced ECC beams

生命的分子机器及其调控网络——2012年全国生物化学与分子生物学学术大会

作者： yang Xiang Qian Gao Chao yan Ping Jiang Sheng'an Li Wenhui Lee yun Zhang Key Laboratory of Animal Models and Human Disease Mechanisms Kunming Institute of ZoologyChinese Academy of Sciences Department of pathology Kunming Medical College

Background:The first line of body’s defense against invading infectious bacteria is provided by the innate immune system,and it relies on the pattern recognition receptors(PRRs),which including Toll like receptors(TLRs) and NOD like receptors(NLRs).NLRs are important components of inflammasomes which are molecular platforms that assembled by hetero-oligomerization of NLRP, ASC and *** the assembly of this macro-molecular platform,pro-caspase-1 would be activated,which subsequently

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Journal of Southeast University(English Edition) 2013年第1期29卷 66-72页

作者：颜嫄许赟汪逊潘金龙东南大学混凝土及预应力混凝土结构教育部重点实验室南京210096

In order to investigate the flexural behaviors of engineered cementitious composites （ECC）, theoretical and experimental researches are done on flexural doublereinforced ECC beams. Based on the assumption of the plane section remaining plane in bending and simplified constitutive models of materials, the calculation methods of load carrying capacities for different critical stages are obtained. Then, these calculation methods are demonstrated by comparing the test results with the calculation results. Finally, based on the proposed theoretical formulae, the effects of the compression strength, compression strain and tension strength of ECC, and the reinforcement ratio on the flexural behaviors of double-reinforced ECC beams are analyzed. The calculated and measured results are in good agreement, which indicates that the theoretical model can be used to predict the momentcurvature response of steel reinforced ECC beams. And the results of parametric studies show that the increase in the compression strength of ECC can greatly improve the flexural performance of beams; the increase in the ultimate compression strain can significantly improve the ultimate curvature and ductility, but has little effect on the load bearing capacity of beams. little effect on the flexural The tensile strength of ECC has behaviors of ECC beams. The increase in the steel reinforcement ratio can lead to significant improvement of the load bearing capacity and the stiffness of beams, but a degradation of the ductility of beams. The theoretical model and parameter analysis results in this paper are instructive for the design of steel reinforced ECC beams.

关键词： engineered cementitious composites (ECC) ultimate carrying capacity ultimate curvature ductility parametric study

胜利褐煤和小龙潭褐煤在甲醇中的热溶及热溶物分析

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燃料化学学报 2016年第1期44卷 15-22页

作者：闫洁赵云鹏肖剑田由甲中国矿业大学煤炭加工与高效利用教育部重点实验室江苏徐州221116

研究了胜利褐煤(SL)和小龙潭褐煤(XLT)在甲醇中的热溶行为,并利用傅里叶变换红外光谱、气相色谱/质谱(GC/M S)和大气压固体分析探针/飞行时间质谱(ASAP/TOF-M S)对320℃热溶物的组成和结构特征进行了分析。两种褐煤热溶物产率均随温度... 详细信息

研究了胜利褐煤(SL)和小龙潭褐煤(XLT)在甲醇中的热溶行为,并利用傅里叶变换红外光谱、气相色谱/质谱(GC/M S)和大气压固体分析探针/飞行时间质谱(ASAP/TOF-M S)对320℃热溶物的组成和结构特征进行了分析。两种褐煤热溶物产率均随温度升高而增加,但240℃后XLT热溶物(SPXLT)产率明显高于SL热溶物(SPSL)。GC/MS分析表明,两种褐煤热溶物以含氧化合物为主,尤其酚类的相对含量超过49%;与SPXLT相比,SPSL中烯烃、芳烃、醚类、羧酸、酯类和有机硫化合物(OSCs)含量较高,而烷烃、酚类、酮类和有机氮化合物含量较低;SPSL中的OSCs以噻吩为主,而SPXLT中的OSCs以硫醇为主。ASAP/TOF-M S可检测出热溶物中大量GC/M S无法检测出的较强极性和难挥发化合物;与SPXLT相比,SPSL中CHO和CHS族分含量较低,而CHN、CHNO、CHOS、CHNS和CHNOS族分含量较高;两种褐煤热溶物中化合物的碳数和双键数(double bond equivalent,DBE)主要分布在3-15和0-10,SPXLT中化合物的碳数和DBE分布相对集中。

关键词：褐煤热溶气相色谱/质谱大气压固体分析探针/飞行时间质谱

基于PCRLB的低轨星座对自由段多目标的多传感器调度算法

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宇航学报 2011年第4期32卷 842-850页

作者：赵砚张寅生易东云张倩国防科技大学理学院长沙410073 北京跟踪与通信技术研究所北京100094 北京航天指挥控制中心北京100094

研究了低轨星座跟踪自由段目标背景下的多目标多传感器调度问题。论述了自由段目标运动模型和星载红外传感器测量模型。考虑到目标出现的时空不确定性,面向系统的跟踪性能,建立了基于突发事件和滚动周期的调度框架以及调度与跟踪的闭环... 详细信息

研究了低轨星座跟踪自由段目标背景下的多目标多传感器调度问题。论述了自由段目标运动模型和星载红外传感器测量模型。考虑到目标出现的时空不确定性,面向系统的跟踪性能,建立了基于突发事件和滚动周期的调度框架以及调度与跟踪的闭环结构。基于此,建立了调度的具体算法。特别地,以调度周期内系统的信息增量最大化为目标,详细设计了基于PCRLB的调度策略性能指标。仿真验证了算法的可行性、优越性以及在动态环境中的适应性。

关键词：多目标多传感器调度后验Cramer-Rao下界信息增量低轨星座中段目标

Study on System Efficiency and Power Flow Optimization for Dual-Mode Hybrid Electric Vehicle

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Study on System Efficiency and Power Flow Optimization for D...

FISITA 2012 World Automotive Congress--Volume 3:Future Automotive Powertrains

作者： Li-jin Han Chang-le Xiang Wei-jing yan yun-long Qi Ran Liu School of Mechanical Engineering Beijing Institute of Technology

Research and/or Engineering Questions/Objective:Most research of the power-split hybrid vehicle haven’t taken the efficiency of the planetary-gear system which changes according to the gear ratio into account and merely consider the power lose based on the mechanical-electric energy conversion and determined the control *** objective of the study is to achieve optimized management and cooperative control of the power flow by building an exact model of hybrid power system and analyzing the ***:The mechanical loss of the Dual-mode coupling mechanism planetary system is caused by gear mesh,clutch friction,oil seal and *** loss has intimated connection with the parameters of the system *** chapter has studied the relationship between system parameters and transmission efficiency of planetary transmission in coupling *** also has built the efficiency model of the planetary transmission in coupling system and amend the model by *** a comprehensive efficiency model of the hybrid vehicle,by considering the power loss of engine,battery,motor and other components and mechanical loss of planetary transmission in coupling system,and this model reflects the distribution of the system power *** we could achieve the optimized control of system power flow under the requirement of the ***:The planetary transmission efficiency and hybrid vehicle comprehensive efficiency has been described by the functions of system power flow distribution *** considering of the equivalence relations between battery pack charge/discharge and engine fuel consumption,this chapter has built the optimized model of system power flow *** of this study:An important limitation of the current study is the calculating of the drag losses of the clutch/brake at very high rotating speed,and the designing of the test bench which should has the ability to measured more than one motor power *** specialize tests of

关键词： Dual-mode HEV System efficiency Power flow optimization Control strategy

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清真寺建筑的象征人类学分析

学术探索 2016年第12期 56-62页

作者：马海云晏妮云南大学法学院云南大学民族研究院云南昆明650031

清真寺是伊斯兰教的核心象征符号,也是伊斯兰教信仰体系和宗教精神的体现。虽然世界各地的清真寺在建筑风格上不尽相同,但在表达宗教象征意义,寓意宗教隐喻方面却具有一致性。清真寺不仅是"认主独一"的核心象征,也有着圣洁与权威、敬畏... 详细信息

清真寺是伊斯兰教的核心象征符号,也是伊斯兰教信仰体系和宗教精神的体现。虽然世界各地的清真寺在建筑风格上不尽相同,但在表达宗教象征意义,寓意宗教隐喻方面却具有一致性。清真寺不仅是"认主独一"的核心象征,也有着圣洁与权威、敬畏与顺从、和平与团结的象征意义。从建筑结构来看,清真寺从外观设计到内部结构都有着深刻的象征性和隐喻性,折射出伊斯兰的文化内涵和宗教精神。

关键词：清真寺象征人类学象征隐喻