检索结果-南通市图书馆

The MON1–CCZ1 complex plays dual roles in autophagic degradation and vacuolar protein transport in rice

Journal of Integrative Plant Biology 2025年第1期67卷 35-54页

作者： Binglei Zhang Yihua Wang yun Zhu Tian Pan Haigang yan Xin Wang Ruonan Jing Hongming Wu Fan Wang yu Zhang Xiuhao Bao Yongfei Wang Pengcheng Zhang yu Chen Erchao Duan Xiaohang Han Gexing Wan Mengyuan yan Xiejun Sun Cailin Lei Zhijun Cheng Zhichao Zhao Ling Jiang Yiqun Bao yulong Ren Jianmin Wan State Key Laboratory of Crop Gene Resources and Breeding National Key Facility for Crop Gene Resources and Genetic ImprovementInstitute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China College of Life Sciences Nanjing Agricultural UniversityNanjing 210095China State Key Laboratory of Crop Genetics&Germplasm Enhancement and Utilization Nanjing Agricultural UniversityNanjing 210095China Zhongshan Biological Breeding Laboratory Nanjing 210095China

Autophagy is a highly conserved cellular program in eukaryotic cells which mediates the degradation of cytoplasmic components through the lysosome,also named the vacuole in ***,the molecular mechanisms underlying the fusion of autophagosomes with the vacuole remain ***,we report the functional characterization of a rice(Oryza sativa)mutant with defects in storage protein transport in endosperm cells and accumulation of numerous autophagosomes in root *** and immunocytochemical experiments showed that this mutant exhibits a defect in the fusion between autophagosomes and *** mutant harbors a loss-of-function mutation in the rice homolog of Arabidopsis thaliana MONENSIN SENSITIVITY1(MON1).Biochemical and genetic evidence revealed a synergistic interaction between rice MON1 and AUTOPHAGY-RELATED 8a in maintaining normal growth and *** addition,the rice mon1 mutant disrupted storage protein sorting to protein storage ***,quantitative proteomics verified that the loss of MON1 function influenced diverse biological pathways including autophagy and vacuolar transport,thus decreasing the transport of autophagic and vacuolar cargoes to ***,our findings establish a molecular link between autophagy and vacuolar protein transport,and offer insights into the dual functions of the MON1–CCZ1(CAFFEINE ZINC SENSITIVITY1)complex in plants.

关键词： autophagic degradation MON1–CCZ1 Rab7 rice vacuolar trafficking

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Relation among Summer Rainfall in South Shandong and High Pressure in South Asia and Atmospheric Circulation

引用

Meteorological and Environmental Research 2011年第7期2卷 41-46页

作者： GAO An-chun,SHEN Pei-lu,LI Bing-wen,HU yan,yu yan-min,ZHU Yi-qing Linyi Meteorological Bureau of Shandong Province,Linyi 276004,China

[Objective] The aim was to study the relation among summer rainfall in south Shandong and high pressure in South Asia and atmospheric circulation.[Method] Taking the precipitation in south Shandong along the Yellow River and Huaihe River,using the NCEP/NCAR data and summer rainfall data in south Shandong in summer from 1961 to 2005,the characteristics of high pressure in South Asia and atmospheric circulation in drought year and flood year in summer in south Shandong Province were *** mechanism of 100 hPa pressure in South Asian influencing precipitation in south Shandong Province was *** interaction of different equipment,different altitude and different system of atmosphere circulation in low and high layer was expounded.[Results] The first mode of EOF decomposition of precipitation in summer in south Shandong Province explained above 63% variances and reflected universal form of *** difference of central position of the central position of height field of high pressure in South Asia in drought and flood year was *** the wind field center was *** the area of SAH was smaller and its eastern ridge line stretched to the Western Pacific between the middle of south Shandong and Changjiang Estuary,flood summer occurred when there was an unusual cyclone lied in the east of 90° E and south of Lake *** area of SAH was larger and its eastern ridge line stretching to the Western Pacific over Changjiang Estuary,drought summer occurred,when there was an unusual anticyclone lied in the east of 90° E and south of Lake *** and summer rainfall also had close relationship with Tele-connection Patterns over the Eurasia continent and EAP *** the height anomaly was in '+-+' form in the north of the Caspian Sea,around Lake Baikal and Kamchatka,and when the height anomaly in East Asia-West Pacific area was in '-+' form from low altitude to high altitude,there was much precipitation in summer;and conversel

关键词： Summer rainfall in the south of Shandong Province Drought and flood High pressure in South Asia Atmospheric circulation China

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Qishen Granules Modulate Metabolism Flexibility Against Myocardial Infarction via HIF-1 α-Dependent Mechanisms in Rats

引用

CHINESE JOURNAL OF INTEGRATIVE MEDICINE 2025年第3期31卷 215-227页

作者： Sun, Xiao-qian Li, Xuan Li, yan-qin Lu, Xiang-yu Liu, Xiang-ning Cui, Ling-wen Wang, Gang Zhang, Man Li, Chun Wang, Wei Beijing Univ Chinese Med Sch Tradit Chinese Med Beijing 100029 Peoples R China Beijing Univ Chinese Med Beijing Key Lab Tradit Chinese Med Syndrome & Form Beijing 100029 Peoples R China Beijing Univ Chinese Med Sch Chinese Mat Med Beijing 100029 Peoples R China Guangzhou Univ Chinese Med Guangzhou 510006 Guangdong Peoples R China

ObjectiveTo assess the cardioprotective effect and impact of Qishen Granules (QSG) on different ischemic areas of the myocardium in heart failure (HF) rats by evaluating its metabolic pattern, substrate utilization, and mechanistic modulation. MethodsIn vivo, echocardiography and histology were used to assess rat cardiac function;positron emission tomography was performed to assess the abundance of glucose metabolism in the ischemic border and remote areas of the heart;fatty acid metabolism and ATP production levels were assessed by hematologic and biochemical analyses. The above experiments evaluated the cardioprotective effect of QSG on left anterior descending ligation-induced HF in rats and the mode of energy metabolism modulation. In vitro, a hypoxia-induced H9C2 model was established, mitochondrial damage was evaluated by flow cytometry, and nuclear translocation of hypoxia-inducible factor-1 alpha (HIF-1 alpha) was observed by immunofluorescence to assess the mechanism of energy metabolism regulation by QSG in hypoxic and normoxia conditions. ResultsQSG regulated the pattern of glucose and fatty acid metabolism in the border and remote areas of the heart via the HIF-1 alpha pathway, and improved cardiac function in HF rats. Specifically, QSG promoted HIF-1 alpha expression and entry into the nucleus at high levels of hypoxia (P<0.05), thereby promoting increased compensatory glucose metabolism;while reducing nuclear accumulation of HIF-1 alpha at relatively low levels of hypoxia (P<0.05), promoting the increased lipid metabolism. ConclusionsQSG regulates the protein stability of HIF-1 alpha, thereby coordinating energy supply balance between the ischemic border and remote areas of the myocardium. This alleviates the energy metabolism disorder caused by ischemic injury.

关键词： Qishen Granules substrate utilization hypoxia-inducible factor-1 alpha pathway energy metabolism heart failure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Punicalagin alleviates hypercholesterolemia in mice through modulating farnesoid X receptor signaling and modulating gut microbiota

引用

Food Science and Human Wellness 2025年第1期14卷 175-189页

作者： Huanhuan Liu Hongli Liu Chunhong yan Jiaxiu Liu yu Cao Guopeng Li Xiaodong Xia State Key Laboratory of Marine Food Processing and Safety Control National Engineering Research Center of SeafoodSchool of Food Science and TechnologyDalian Polytechnic UniversityDalian 116034China Beijing Advanced Innovation Center for Food Nutrition and Human Health College of Food Science and Nutritional EngineeringChina Agricultural UniversityBeijing 100083China

Punicalagin has been demonstrated to exhibit anti-oxidant and anti-inflammatory properties,but whether and how it could impact hypercholesterolemia remains not fully *** aim of this study was to investigate the influence of punicalagin on hypercholesterolemia in mice and its related *** 6 weeks'intervention,punicalagin significantly reduced serum total cholesterol and low-density lipoprotein cholesterol(LDL-C)levels in mice fed a high-fat high-cholesterol(HFHC)***,punicalagin supplementation lowered hepatic cholesterol level,which corresponded to the down-regulation of cholesterol synthesis genes(Fdps,Cyp51)and up-regulated bile acid synthesis genes(Cyp7a1,Cyp27a1).In addition,bile acid reabsorption was retarded in punicalagin-fed mice through down-regulating ileal apical sodium-dependent BA transporter(ASBT).Furthermore,intestinal farnesoid X receptor(FXR)-fibroblast growth factor 15(Fgf15)pathway was inhibited while hepatic FXR-small heterodimeric partner(SHP)pathway was activated in punicalagin *** analysis and targeted metabolomics showed that punicalagin decreased the abundance of bile-salt hydrolase(BSH)-producing bacteria(Clostridiaceae and Bifidobacteriaceae)and the ratio of primary BAs to secondary *** conclusion,the cholesterol-lowering effect of punicalagin partly through down-regulating cholesterol synthesis and increasing cholesterol catabolism,which could be achieved by regulating gut microbiota,altering bile acid composition and modulating FXR signaling *** findings indicate the potential application of punicalagin-related products as an alternative strategy for hypercholesterolemia prevention and mitigation.

关键词： Punicalagin Hypercholesterolemia Farnesoid X receptor Bile acid metabolism Gut microbiota

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Riemann-Stieltjes算子的本性范数

引用

数学学报（中文版） 2016年第6期59卷 847-858页

作者：刘晓曼刘永民于燕燕东南大学数学系南京210096 江苏师范大学数学与统计学院徐州221116 徐州工程学院数学与物理科学学院徐州221018

本文建立在从Hardy空间H^p到Zygmund型空间Z_μ的Riemann-Stieltjes算子I_(g,φ)和J_(g,φ)的有界性和紧性的特征的基础上,构造了H^p中一些检验函数,运用本性范数的定义与解析函数的性质,给出了算子I_(g,φ)和J_(g,φ)本性范数的估计.

关键词：本性范数 Hardy空间 Zygmund型空间 Riemann-Stieltjes算子

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Integration of Electrical Properties and Polarization Loss Modulation on Atomic Fe–N‑RGO for Boosting Electromagnetic Wave Absorption

引用

Nano-Micro Letters 2025年第2期17卷 517-532页

作者： Kaili Zhang yuefeng yan Zhen Wang Guansheng Ma Dechang Jia Xiaoxiao Huang yu Zhou State Key Laboratory of Precision Welding&Joining of Materials and Structures Harbin Institute of TechnologyHarbin 150001People’s Republic of China School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001People’s Republic of China MIIT Key Laboratory of Advanced Structural‑Functional Integration Materials&Green Manufacturing Technology Harbin Institute of TechnologyHarbin 150001People’s Republic of China

Developing effective strategies to regulate graphene’s conduction loss and polarization has become a key to expanding its application in the electromagnetic wave absorption(EMWA)*** on the unique energy band structure of graphene,regulating its bandgap and electrical properties by introducing heteroatoms is considered a feasible ***,metal-nitrogen doping reduced graphene oxide(M–N-RGO)was prepared by embedding a series of single metal atoms M–N_(4) sites(M=Mn,Fe,Co,Ni,Cu,Zn,Nb,Cd,and Sn)in RGO using an N-coordination atom-assisted *** composites had adjustable conductivity and polarization to optimize dielectric loss and impedance matching for efficient EMWA *** results showed that the minimum reflection loss(RL_(min))of Fe–N-RGO reaches−74.05 dB(2.0 mm)and the maximum effective absorption bandwidth(EAB_(max))is 7.05 GHz(1.89 mm)even with a low filler loading of only 1 wt%.Combined with X-ray absorption spectra(XAFS),atomic force microscopy,and density functional theory calculation analysis,the Fe–N_(4) can be used as the polarization center to increase dipole polarization,interface polarization and defect-induced polarization due to d-p orbital hybridization and structural ***,electron migration within the Fe further leads to conduction loss,thereby synergistically promoting energy *** study demonstrates the effectiveness of metal-nitrogen doping in regulating the graphene′s dielectric properties,which provides an important basis for further investigation of the loss mechanism.

关键词： Electromagnetic wave absorption Fe-N-RGO Dipole polarization Conduction loss Impedance matching

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Analysis of Micromechanical Properties at the Interface of Pre-wet SBS Modified Asphalt Mixture Based on Molecular Simulation Technology

引用

Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 103-113页

作者： CHEN Wuxing CHEN Shuang yu yan ZHANG Jiangyi XU Haiyang GUO Wei School of Mines China University of Mining and TechnologyXuzhou 221000China College of Construction Engineering Jilin Uni-versityChangchun 130026China

The pre-wetting of aggregate surface is a means to improve the interface performance of SBS modified asphalt and *** effect of pre-wetting technology on the interaction between SBS modified asphalt and aggregate was analyzed by molecular dynamics *** diffusion coefficient and concentration distribution of SBS modified asphalt on aggregate surface are *** simulation results show that the diffusion coefficient of the aggregate surface of SBS modified asphalt is increased by 47.6%and 70.5%respectively after 110#asphalt and 130#asphalt are *** concentration distribution of SBS modified asphalt on the aggregate surface after pre-wetting is more *** to the results of interface energy calculation,the interface energy of SBS modified bitumen and aggregate can be increased by about 5%after *** to the results of molecular dynamics simulation,the pre-wetting technology can effectively improve the interface workability of SBS modified bitumen and aggregate,so as to improve the interface performance.

关键词： pre-wet oil-stone interface interface interaction interface mechanics molecular dynamics simulation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Stereocomplex Crystallites Improve the Stability of Biodegradable Poly(L-lactic acid)/Poly(D-lactic acid)Melt-Blown Nonwovens

引用

Chinese Journal of Polymer Science 2025年第2期43卷 368-379页

作者： Jin-Shuo yu yue-Wei Huan Hong-Wei Pan Zhi-Gang Liu yan Zhao Zhi-Yong Tan Jun-Jia Bian Hui-Li yang Hui-Liang Zhang Key Laboratory of Polymer Ecomaterials Chinese Academy of SciencesChangchun Institute of Applied ChemistryChangchun130022China College of Material and Engineering School of Chemical EngineeringEngineering Research Center of Synthetic Resin and Special FiberMinistry of EducationChangchun University of TechnologyChangchun130012China Shandong Fufeng Fermentation Co. Ltd.Shandong276600China National Engineering Research Center of Corn Deep Processing Jilin COFCO Biochemistry Co.Ltd.Changchun130033China

Poly(lactic acid)(PLA)is a biodegradable and eco-friendly polymer that is increasingly being incorporated into various applications in contemporary ***,the limited stability of PLA-based products remains a significant challenge for their broader use in various *** this study,poly(L-lactic acid)(PLLA)/poly(D-lactic acid)(PDLA)melt-blown nonwovens were prepared by melt *** structure,thermal properties,thermal stability,biodegradability and crystalline morphology of the melt-blown nonwovens were *** and WAXD confirmed the formation of stereocomplex(SC)crystallites in the PLLA *** storage modulus(G′),loss modulus(G″),and complex viscosity(∣η^(*)∣)of the PLLA/PDLA blend increased with an increase in SC crystallite *** thermal degradation temperatures of PLLA/PDLA melt-blown nonwovens increased with the incorporation of SC crystallites,and the maximum rate of decomposition increased to 385.5℃,thus enhancing the thermal *** with neat PLLA melt-blown nonwovens,the hydrophobicity of PLLA/PDLA melt-blown nonwovens was improved,and WCA increased to 139.7°.The SC crystallites were more resistant to degradation by proteinase K compared to neat ***,the degradation rate of PLLA/PDLA melt-blown nonwovens remained at a high *** work provides an effective strategy to obtain high-performance PLLA melt-blown nonwovens.

关键词： PLLA PDLA Melt-blown nonwovens Stereocomplex crystallites Thermal stability Enzymatic degradation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Femtosecond mode-locking and soliton molecule generation based on a GaAs saturable absorber

引用

Chinese Physics B 2025年第1期34卷 344-349页

作者： Chen-yan Zhang Xin-He Dou Zhen Chen Jing-Han Zhao Wei Sun Ze-yu Fan Tao Zhang Hao Teng Zhi-Guo Lv School of Physical Science and Technology Inner Mongolia UniversityHohhot 010021China Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China

In the last few years,research on advanced ultrafast photonic devices has attracted great interest from laser *** a semiconductor material with excellent nonlinear saturation absorption characteristics,Ga As has been used in solidstate and fiber lasers as a ***,the pulse widths that have been reported in the searchable published literature are all long and the shortest is tens of *** pulse widths,desired for a variety of applications,have not yet been reported in Ga As-based pulsed *** this work,we further explore the nonlinear characteristics of Ga As that has been magnetron sputtered onto the surface of a tapered fiber and its application in the generation of femtosecond lasing via effective dispersion optimization and nonlinearity *** the enhanced interaction between evanescent waves and Ga As nanosheets,mode-locked soliton pulses as short as 830 fs are generated at repetition rates of 4.64 *** far as we know,this is the first time that femtosecond-level pulses have been generated with a Ga As-based saturable *** addition,soliton molecules,including in the dual-pulse state,are also realized under stronger *** work demonstrates that Ga As-based photonic devices have good application prospects in effective polymorphous ultrashort pulsed laser generation.

关键词： GaAs saturable absorber mode-locking soliton molecule

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Unveiling solid-solid contact states in all-solid-state lithium batteries:An electrochemical impedance spectroscopy viewpoint

引用

Journal of Energy Chemistry 2025年第2期101卷 16-22页

作者： Jin-Liang Li Liang Shen Zi-Ning Cheng Jun-Dong Zhang Ling-Xuan Li yu-Tong Zhang yan-Bin Gao Chunli Guo Xiang Chen Chen-Zi Zhao Rui Zhang Qiang Zhang Tsinghua Center for Green Chemical Engineering Electrification Beijing Key Laboratory of Green Chemical Reaction Engineering and Technology Department of Chemical Engineering Tsinghua University College of Materials Science and Engineering Taiyuan University of Technology Advanced Research Institute of Multidisciplinary Science School of Materials Science and Engineering Beijing Institute of Technology Beijing Huairou Laboratory Institute for Carbon Neutrality Tsinghua University Shanxi Research Institute for Clean Energy Tsinghua University

All-solid-state lithium batteries（ASSLBs） are strongly considered as the next-generation energy storage devices for their high energy density and intrinsic *** solid-solid contact between lithium metal and solid electrolyte plays a vital role in the performance of working ASSLBs,which is challenging to investigate quantitatively by experimental *** work proposed a quantitative model based on the finite element method for electrochemical impedance spectroscopy simulation of different solid-solid contact states in *** the assistance of an equivalent circuit model and distribution of relaxation times,it is discovered that as the number of voids and the sharpness of cracks increase,the contact resistance Rcgrows and ultimately dominates the battery *** accurate fitting,inverse proportional relations between contact resistance Rcand（1-porosity） as well as crack angle was *** contribution affords a fresh insight into clarifying solid-solid contact states in ASSLBs.

关键词： All-solid-state lithium batteries Distribution of relaxation times Electrochemical impedance spectroscopy Equivalent circuit model Finite element method Solid-solid contacts

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：