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World Journal of Clinical Cases 2021年第14期9卷 3327-3333页

作者： Yv Zhang Sheng-Yuan Wang Da-Zhi Guo shu-Yi pan yan Lv Department of Hyperbaric Oxygen The Sixth Medical Center of PLA General HospitalBeijing 100048China

BACKGROUND Acute flaccid paralysis(AFP)and neurogenic respiratory failure rarely occur in *** the end of 2018,some children with such symptoms were admitted to our *** this study,we aimed to assess two children with AFP and neurogenic respiratory failure associated with enterovirus D68(EV-D68).CASE SUMMARY Two children admitted to our hospital presented with symptoms and imaging results different from those of acute disseminated encephalomyelitis and hand,foot,and mouth *** main symptoms were AFP and neurogenic respiratory *** resonance imaging showed severe inflammatory injury mainly to the anterior horn cells of the spinal *** and cerebrospinal fluid samples were collected to assess for pathogens,including bacteria,tuberculosis,cryptococcus,herpes virus,and coxsackie virus,and the results were *** the beginning,the two cases were not assessed for EV-D68 in the nasopharyngeal,blood,and cerebrospinal fluid *** 2 mo later,EVD68 was detected in the stool sample of one of the *** symptom of AFP was caused by injury to the anterior horn cells at levels C5-L5 of the spinal cord,while neurogenic respiratory failure was at levels *** We should pay attention to the detection and diagnosis of EV-D68 and make efforts to develop antivirus drugs and vaccines.

关键词： Infection Enterovirus D68 Flaccid Paralysis Neurogenic Respiratory failure Case report

Simulation Research on the Effect of Cooled EGR, Supercharging and Compression Ratio on Downsized SI Engine Knock

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Chinese Journal of Mechanical Engineering 2013年第2期26卷 341-350页

作者： shu Gequn pan Jiaying WEI Haiqiao SHI Ning State Key Laboratory of Engines Tianjin University

Knock in spark-ignition（SI） engines severely limits engine performance and thermal efficiency. The researches on knock of downsized SI engine have mainly focused on structural design, performance optimization and advanced combustion modes, however there is little for simulation study on the effect of cooled exhaust gas recirculation（EGR） combined with downsizing technologies on SI engine performance. On the basis of mean pressure and oscillating pressure during combustion process, the effect of different levels of cooled EGR ratio, supercharging and compression ratio on engine dynamic and knock characteristic is researched with three- dimensional KIVA-3V program coupled with pressure wave equation. The cylinder pressure, combustion temperature, ignition delay timing, combustion duration, maximum mean pressure, and maximum oscillating pressure at different initial conditions are discussed and analyzed to investigate potential approaches to inhibiting engine knock while improving power output. The calculation results of the effect of just cooled EGR on knock characteristic show that appropriate levels of cooled EGR ratio can effectively suppress cylinder high-frequency pressure oscillations without obvious decrease in mean pressure. Analysis of the synergistic effect of cooled EGR, supercharging and compression ratio on knock characteristic indicates that under the condition of high supercharging and compression ratio, several times more cooled EGR ratio than that under the original condition is necessarily utilized to suppress knock occurrence effectively. The proposed method of synergistic effect of cooled EGR and downsizing technologies on knock characteristic, analyzed from the aspects of mean pressure and oscillating pressure, is an effective way to study downsized SI engine knock and provides knock inhibition approaches in practical engineering.

关键词： exhaust gas recirculation compression ratio knock pressure wave equation pressure oscillation

A broad absorption line outflow associated with the broad emission line region in the quasar SDSS J075133.35+134548.3

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Research in Astronomy and Astrophysics 2021年第3期21卷 133-148页

作者： Bo Liu Hong-yan Zhou Xin-Wen shu Shao-Hua Zhang Tuo Ji Xiang pan Peng Jiang Key Laboratory for Research in Galaxies and Cosmology University of Science and Technology of ChinaHefei 230026China Polar Research Institute of China Shanghai 200136China Department of Physics Anhui Normal UniversityWuhu 241000China

We report on the discovery of unusual broad absorption lines(BALs)in the bright quasar SDSS J075133.35+134548.3 at z~1,using archival and newly obtained optical and NIR spectroscopic *** BALs are detected reliably in HeⅠ*λ3889,HeⅠ*λ10830 and tentatively in AlⅢ,MgⅡ.These BALs show complex velocity structures consisting of two major components:a high-velocity component(HV),with a blueshifted velocity range ofΔv_(HV)~9300--3500 km s^(-1),which can be reliably detected in HeⅠ*λ10830,and tentatively in AlⅢand MgⅡ,whereas it is undetectable in HeⅠ*λ3889;and a low-velocity component(LV),withΔv_(LV)~3500--1800 km s^(-1),is only detected in HeⅠ*λ3889 and HeⅠ*λ*** the BALs from different ions,the HV outflowing gas can be constrained to have a density of nH~10^(10.3)-10^(11.4) cm^(-3),a column density of NH~10^(21) cm^(-2)and an ionization parameter of U~10^(-1.83)-10^(-1.72);inferring a distance of RHV~0.5 pc from the central continuum source with a monochromatic luminosityλLλ(5100)=7.0×10^(45)erg s^(-1)at 5100 *** distance is remarkably similar to that of the normal broad line region(BLR)estimated from reverberation experiments,suggesting association of the BLR and the HV BAL outflowing ***,a blueshifted component is also detected in AlⅢand MgⅡbroad emission lines(BELs),and the AlⅢ/MgⅡof such a BEL component can be reproduced by the physical parameters inferred from the HV BAL *** LV BAL gas likely has a larger column density,a higher ionization level and hence a smaller distance than the HV BAL *** spectroscopy with a high S/N ratio and broader wavelength coverage is needed to confirm this to shed new light on the possible connection between BALs and BELs.

关键词： quasars:emission lines quasars:broad absorption line quasars:individual(SDSS J075133.35+134548.3)

Nerve growth factor protects against palmitic acid- induced injury in retinal ganglion cells

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Neural Regeneration Research 2016年第11期11卷 1851-1856页

作者： pan-shi yan shu Tang Hai- feng Zhang Yuan-yuan Guo Zhi-wen Zeng Qiang Wen Department of Ophthalmology First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China Department of Pharmacy First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China Department of Biochemistry and Molecular Biology School of Basic Medicine Zhengzhou University Zhengzhou Henan Province China Shenzhen Mental Health Center and Shenzhen Key Lab for Psychological Healthcare Shenzhen Guangdong Province China Department of Clinical Pharmacology School of Basic Medicine Zhengzhou University Zhengzhou Henan Province China

Accumulating evidence supports an important role for nerve growth factor （NGF） in diabetic retinopathy. We hypothesized that NGF has a protective effect on rat retinal ganglion RGC-5 cells injured by palmitic acid （PA）, a metabolic factor implicated in the development of dia- betes and its complications. Our results show that PA exposure caused apoptosis of RGC-5 cells, while NGF protected against PA insult in a concentration-dependent manner. Additionally, NGF significantly attenuated the levels of reactive oxygen species （ROS） and malondialde- hyde （MDA） in RGC-5 cells. Pathway inhibitor tests showed that the protective effect of NGF was completely reversed by LY294002 （PI3K inhibitor）, Akt VIII inhibitor, and PD98059 （ERK1/2 inhibitor）. Western blot analysis revealed that NGF induced the phosphorylation of Akt/FoxO1 and ERK1/2 and reversed the PA-evoked reduction in the levels of these proteins. These results indicate that NGF protects RGC-5 cells against PA-induced injury through anti-oxidation and inhibition of apoptosis by modulation of the PI3K/Akt and ERK1/2 signaling pathways.

关键词： nerve regeneration RGC-5 cells palmitic acid nerve growth factor apoptosis PI3K Akt FoxOl ERK1/2 neural regeneration

Progress in the application of ocean color remote sensing in China

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Acta Oceanologica Sinica 2008年第4期27卷 1-16页

作者： pan Delu BAI yan State Key Laboratory of Satellite Ocean Environment Dynamic Second Institute of Oceanography State Oceanic Administration Hangzhou 310012 China

After many years＇ endeavor of research and application practice, the ocean color remote sensing in China has been growing into a new technique with valuable practicality from its initiate stage of trial research. With the aim of operational service, several kinds of ocean color remote sensing application systems have been developed and realized the long-term marine environmental monitoring utilizing the real-time or near real-time satellite and airborne remote sensing data. New progresses in the technology and application of ocean color remote sensing in China are described, including the research of key techniques and the development of various application systems. Meanwhile, according to the application status and demand, the prospective development of Chinese ocean color remote sensing is brought forward. With Chinese second ocean color satellite （ HY-1 B） orbiting on 11 April 2007 and the development of airborne ocean color remote sensing system for Chinese surveillance planes, great strides will take place in Chinese ocean color remote sensing application with the unique function in marine monitoring, resources management and national security, etc.

关键词： ocean color remote sensing operational application system Chinese ocean color satellite series HY-1 AfB

Synthesis of low-cost porous ceramic microspheres from waste gangue for dye adsorption

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Journal of Advanced Ceramics 2018年第1期7卷 30-40页

作者： shu yan Yiming pan Lu WANG Jingjing LIU Zaijuan ZHANG Wenlong HUO Jinlong yanG Yong HUANG State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and Engineering Tsinghua University School of Materials Science and Engineering Dalian Jiaotong University

Low-cost porous ceramic microspheres from waste gangue were prepared by simple spray drying and subsequent calcination. Effects of calcination temperature on phase and microstructure evolution, specific surface area, pore structure, and dye adsorption mechanism of the microspheres were investigated systematically. Results showed that the microspheres were spherical, with some mesopores both on the surface and inside the spheres. The phase kept kaolinite after calcined at 800 and 900 ℃ and transformed into mullite at 1000 ℃. The microspheres calcined at 800 ℃ showed larger adsorption capacity and removal efficiency than those calcined at higher temperatures. Methylene blue(MB) and basic fuchsin(BF) removal efficiency reached 100% and 99.9% with the microsphere dosage of 20 g/L, respectively, which was comparable to that of other low-cost waste adsorbents used to remove dyes in the literature. Adsorption kinetics data followed the pseudosecond-order kinetic model, and the isotherm data fit the Langmuir isotherm model. The adsorption process was attributed to multiple adsorption mechanisms including physical adsorption, hydrogen bonding, and electrostatic interactions between dyes and gangue microspheres. The low-cost porous microspheres with excellent cyclic regeneration properties are promising absorbent for dyes in wastewater filtration and adsorption treatment.

关键词： adsorption microspheres calcination microstructure equilibrium

Impact of parenchyma-preserving surgical methods on treating patients with solid pseudopapillary neoplasms:A retrospective study with a large sample size

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World Journal of Gastrointestinal Surgery 2022年第2期14卷 174-184页

作者： Yu-Qiong Li shu-Bo pan shu-shu yan Zhen-Dong Jin Hao-Jie Huang Li-Qi Sun Department of Gastroenterology Changhai HospitalShanghai 200433China Department of Gastroenterology Suzhou Science and Technology Town HospitalSuzhou 215000Jiangsu ProvinceChina Department of Anesthesiology Changhai HospitalShanghai 200433China Department of Gastroenterology 72^(nd)Group Army HospitalHuzhou UniversityHuzhou 313000Zhejiang ProvinceChina

BACKGROUND Solid pseudopapillary neoplasm of the pancreas(SPN)is a rare neoplasm that mainly affects young *** To evaluate the impact of parenchyma-preserving surgical methods(PPMs,including enucleation and central pancreatectomy)in the treatment of SPN *** From 2013 to 2019,patients who underwent pancreatectomy for SPNs were retrospectively *** baseline characteristics,intraoperative index,pathological outcomes,short-term complications and long-term follow-up data were compared between the PPM group and the conventional method(CM)*** In total,166 patients were included in this *** them,33 patients(19.9%)underwent *** of the tumors(104/166,62.7%)were found *** the parameters between groups,the hospital stay d(12.35 vs 13.5 d,P=0.49),total expense(44213 vs 54084 yuan,P=0.21),operation duration(135 vs 120 min,P=0.71),and intraoperative bleeding volume(200 vs 100 mL,P=0.49)did not differ between *** pathological outcomes,tumor size(45 vs 32 mm,P=0.07),Ki67 index(P=0.53),peripheral tissue invasion(11.3%vs 9.1%,P=0.43)and positive margin status(7.5%vs 6%,P=0.28)also did not differ between ***,PPM did not increase the risk of severe postoperative pancreatic fistula(3.8%vs 3.0%,P=0.85)or tumor recurrence(3.0%vs 6.0%,P=0.39).However,the number of patients who had exocrine insufficiency during follow-up was significantly lower in the PPM group(21.8%vs 3%,P=0.024).CM was identified as an independent risk factor for pancreatic exocrine insufficiency(odds ratio=8.195,95%confident interval:1.067-62.93).CONCLUSION PPM for SPN appears to be feasible and safe for preserving the exocrine function of the pancreas.

关键词： Solid pseudopapillary neoplasm Surgical resection Parenchyma-preserving method pancreatic exocrine insufficiency

Effects of boundary slippage on thin-film lubricationbetween two nonparallel plane plates

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Acta Mechanica Sinica 2012年第3期28卷 625-630页

作者： shu-Hao Ban Xiao-yan Li College of Mechanical and Energy Engineering Changzhou University

Hydrodynamic lubrications between two plane plates with an intersection angle θ have been investigated us- ing the boundary slippage theory, and relations are obtained between dimensionless pressures and coordinate x, between bearing capacity, friction force, friction coefficient and di- mensionless slipping size factor. The results show that bear- ing capacity of two plane plates without boundary slippage significantly increases with increasing intersection angle θ when 0 〈 θ 〈 1°, whereas decreases with increasing in- tersection angle 0 when θ 〉 1°. The results also show that negative pressure occurs in fluid entrance region and bearing capacity decreases, and friction force and friction coefficient increase with the increase of dimensionless slipping size fac- tor.

关键词： Bearing capacity Boundary slippage Dimen-sionless slipping size factor Friction coefficient Hydrody-namic lubrication Negative pressure

毛竹PheTCP19b基因可变剪接体对芽发育的影响

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农业生物技术学报 2025年第1期33卷 43-54页

作者：郝琴申孜闫小玲周敏舒郭小勤浙江农林大学竹子研究院/省部共建亚热带森林培育国家重点实验室

可变剪接(alternative splicing, AS)是一种转录后的修饰过程，在生物体各种生理过程中发挥重要作用。TCP是一种植物特有的转录因子，参与植物多种生长发育调控过程。为深入探究毛竹(Phyllostachys edulis) TCP19b基因可变剪接体的表达... 详细信息

可变剪接(alternative splicing, AS)是一种转录后的修饰过程，在生物体各种生理过程中发挥重要作用。TCP是一种植物特有的转录因子，参与植物多种生长发育调控过程。为深入探究毛竹(Phyllostachys edulis) TCP19b基因可变剪接体的表达特性及生物学功能，本研究采用RT-PCR技术克隆了毛竹TCP19b基因全长CDS，采用qRT-PCR技术和GUS组织染色分析了可变剪接体的表达量及表达部位，通过亚细胞定位及遗传转化分析了可变剪接体编码蛋白的定位及生物学功能。结果显示，毛竹PheTCP19b基因发生了可变剪接，产生了2种可变剪接体PheTCP19bα和PheTCP19bβ，分别编码346和382个氨基酸，2种可变剪接体都包含保守的bHLH结构域。PheTCP19b与水稻(Oryza sativa) OsTCP19亲缘关系最近。2个可变剪接体的组织特异性表达模式存在一定差异，PheTCP19bα的组织特异性强，而PheTCP19bβ表现出组成型表达特性，油菜素内酯(brassinolide, BR)可诱导2个可变剪接体的表达。2个可变剪接体蛋白均富集在细胞核。PheTCP19bα和PheTCP19bβ均可以将拟南芥(Arabidopsis thaliana) brc1突变体多分枝表型回补到野生型表型。本研究为进一步探讨PheTCP19b基因不同剪接体在芽发育过程中的分子机制提供了基础资料。

关键词：毛竹 TCP转录因子可变剪接(AS) 芽发育油菜素内酯(BR)

Ranking environmental projects model based on multicriteria decision-making and the weight sensitivity analysis

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Journal of Systems Engineering and Electronics 2007年第3期18卷 534-539页

作者： Jiang yan Tian Dagang pan Yue Coll. of Management Univ. of Shanghai for Science and Technology Shanghai 200093 P. R. China Dept. of Control Science and Engineering Huazhong Univ. of Science and Technology Wuhan 430074 P. R. China

With the fast growth of Chinese economic, more and more capital will be invested in environmental projects. How to select the environmental investment projects （alternatives） for obtaining the best environmental quality and economic benefits is an important problem for the decision makers. The purpose of this paper is to develop a decision-making model to rank a finite number of alternatives with several and sometimes conflicting criteria. A model for ranking the projects of municipal sewage treatment plants is proposed by using exports＇ information and the data of the real projects. And, the ranking result is given based on the PROMETHEE method. Furthermore, by means of the concept of the weight stability intervals （WSI）, the sensitivity of the ranking results to the size of criteria values and the change of weights value of criteria are discussed. The result shows that some criteria, such as “proportion of benefit to project cost”, will influence the ranking result of alternatives very strong while others not. The influence are not only from the value of criterion but also from the changing the weight of criterion. So, some criteria such as “proportion of benefit to project cost” are key critera for ranking the projects. Decision makers must be cautious to them.

关键词： multicriteria decision-making ranking environmental projects model PROMETHEE method sensitivity analysis weight stability intervals.