检索结果-南通市图书馆

Clinical value of combining epirubicin with mindfulness intervention in patients with urinary system tumors and depression

引用

World Journal of Psychiatry 2025年第1期15卷 54-62页

作者： Juan Liu yan-ping guo yan-Mei Lu Bei-Lin Wang Department of Urology Surgery Zhumadian Central HospitalZhumadian 463000Henan ProvinceChina Department of Psychiatry Zhumadian Mental HospitalZhumadian 463000Henan ProvinceChina

BACKGROUND Urinary system tumors often cause negative psychological symptoms,such as depression and dysphoria which significantly impact immune function and indirectly affect cancer *** epirubicin(EPI)is recommended by the European Association of Urology and can improve prognosis,its long-term use can cause toxic side effects,reduce treatment compliance,and increase psycho-logical ***,an appropriate intervention mode is *** This was a retrospective study including 110 patients with urinary system tumors and depression admitted to Zhumadian Central Hospital between March 2021 and July *** were divided into conventional(n=55)and joint inter-vention(n=55)*** conventional group received mitomycin and routine nursing,while the joint intervention group received EPI and mindfulness *** groups underwent three cycles of *** function(CD4+cells,CD8+cells,CD4+/CD8+ratio),tumor marker levels[urinary bladder cancer antigen(UBC),bladder tumor antigen(BTA)and nuclear matrix protein 22(NMP22)],quality of life questionnaire-core 30(QLQ-C30),17-item Hamilton depression scale(HAMD-17),and cancer-related fatigue[cancer fatigue scale(CFS)]were *** reactions and nursing satisfaction were recorded and *** Post-intervention,CD4+,CD8+,and CD4+/CD8+levels increased in both groups,with the joint intervention group showing more significant improvement(P<0.05).Tumor marker levels(NMP22,BTA,and UBC)were lower in the joint intervention group compared to the conventional group(P<0.05).The joint intervention group also showed a greater reduction in HAMD-17 scores(9.38±3.12 vs 15.45±4.86,P<0.05),higher QLQ-C30 scores,and lower CFS scores(both P<0.05).Additionally,the joint intervention group had a lower incidence of adverse reactions and higher nursing satisfaction(P<0.05).CONCLUSION EPI combined with mindfulness intervention significantly improved clinical outcomes in patients with urinar

关键词： Urinary system tumor Bladder cancer Prostate cancer Depression Epirubicin

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Artificial intelligence advances drug delivery system and its clinical transition

引用

Science Bulletin 2025年第3期70卷 305-308页

作者： Hui Wang Xiao-yan You guo-ping Zhao Master Lab for Innovative Application of Nature Products National Center of Technology Innovation for Synthetic BiologyTianjin Institute of Industrial BiotechnologyChinese Academy of Sciences(CAS)Tianjin 300308China Henan Engineering Research Center of Food Microbiology College of Food and BioengineeringHenan University of Science and TechnologyLuoyang 471023China Haihe Laboratory of Synthetic Biology Tianjin 300308China CAS-Key Laboratory of Synthetic Biology CAS Center for Excellence in Molecular Plant SciencesShanghai Institute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200032China CAS Key Laboratory of Quantitative Engineering Biology Shenzhen Institute of Synthetic BiologyShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China

Since November 2022,ChatGPT,an artificial intelligence(AI)chatbot,has rapidly captured global attention for its detailed responses and articulated answers across a broad spectrum of knowledge domains[1],[2].All industries will reorient around it,prompting a reevaluation of how this technology could further promote scientifical research and its clinical applications.

关键词： system transition spectrum

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

K物质在大鼠中脑导水管周围灰质中参与痛觉调制的作用

引用

中国临床康复 2006年第26期10卷 78-79页

作者：闫国平解放军第四六四医院神经内科天津市300381

目的:分析K物质在大鼠中脑导水管周围灰质中参与痛觉调制的作用,揭示内源性镇痛系统的神经递质机制。方法:实验于2004-03/09在武装警察部队医学院完成。选择6周龄雄性SD大鼠13只,实验过程中静脉持续给予戊巴比妥钠3～6mg/(kg·h)以维持... 详细信息

目的:分析K物质在大鼠中脑导水管周围灰质中参与痛觉调制的作用,揭示内源性镇痛系统的神经递质机制。方法:实验于2004-03/09在武装警察部队医学院完成。选择6周龄雄性SD大鼠13只,实验过程中静脉持续给予戊巴比妥钠3～6mg/(kg·h)以维持大鼠浅麻状态,据鼠脑图谱确定中脑导水管周围灰质的坐标,采用核团内微量注射,以甩尾反射潜伏期为痛阈指标。K物质溶于0.01mmol/L的醋酸中,K物质注射量为1g/L,以辐射热照射大鼠尾端1/3部腹侧皮肤3mm×6mm。实验开始时调整电压强度,使甩尾反射潜伏期为3.5～4.5s。若甩尾反射潜伏期超过7s,则将辐射热源移开鼠尾,以免烫伤皮肤。间隔5min测1次甩尾反射潜伏期,实验开始时连续测定3次,取其均值作为基础对照值。以后测定9次。结果:实验动物13只在实验过程中无死亡,均进入结果分析。大鼠甩尾反射潜伏期基础对照值为(3.63±0.31)s。中脑导水管周围灰质内注入K物质后5,10,15,20,25,30min,甩尾反射潜伏期分别为(4.97±0.42)s,(5.63±0.48)s,(6.51±0.56)s,(5.06±0.41)s,(3.72±0.31)s,(3.66±0.29)s;中脑导水管周围灰质内注入K物质后5～20min甩尾反射潜伏期明显延长(t=9.25、12.25、16.23、10.03,P<0.001)。结论:K物质可能激活起自中脑导水管周围灰质的下行抑制通路,提示中脑导水管周围灰质在痛觉的下行抑制过程中起作用。

关键词：镇痛脑导水管水管周灰质

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

单电源220kV多级供电线路继电保护整定策略

引用

电力系统保护与控制 2009年第20期37卷 139-144页

作者：汤大海严国平镇江供电公司江苏镇江212001 江苏省电力公司江苏南京210024

介绍了江苏220kV电网分区运行情况和镇江电网分区运行的现状,分析了镇江220kV电网分为东、西两片运行后,形成了镇江城区单电源220kV多级供电线路的供电网络,针对这一网络提出了单电源三级220kV供电线路继电保护整定计算策略,并通过对一... 详细信息

介绍了江苏220kV电网分区运行情况和镇江电网分区运行的现状,分析了镇江220kV电网分为东、西两片运行后,形成了镇江城区单电源220kV多级供电线路的供电网络,针对这一网络提出了单电源三级220kV供电线路继电保护整定计算策略,并通过对一个实际网络的整定计算,指出了上下级保护之间存在不配合情况;可以采取提高电源开关的稳定限额的办法,来改善上下级保护之间第Ⅰ段和第Ⅱ段的配合情况;但由于电源开关保护限额的限制,仍存在上下级后备段保护之间不配合情况。建议应通过规划,改善220kV供电网络,来减少单电源多级串供220kV线路的级数或没有多级串供的220kV供电线路,并在单电源供电线路上装设能够全线速动的光纤分相电流差动保护,来改善单电源多级串供的220kV线路保护之间快速保护段之间的配合性能。

关键词： 220 kV线路继电保护单电源供电方式整定计算配合策略

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

考虑限位的碟簧初始压缩位移研究

引用

工程设计学报 2015年第5期22卷 505-508页

作者：严国平肖岚中冶南方工程技术有限公司技术研究院湖北武汉443002 武汉船舶职业技术学院经济与管理学院湖北武汉430050

为探究特定工况下碟簧参数的选择及优化方法,以碟簧为研究对象,分析了碟簧特定工况下参数的组成,并根据其工作原理及约束条件,通过数学的方法给出了考虑限位的碟簧初始压缩位移的解析表达式.基于MATLAB数值分析软件,建立了计算的数学模... 详细信息

为探究特定工况下碟簧参数的选择及优化方法,以碟簧为研究对象,分析了碟簧特定工况下参数的组成,并根据其工作原理及约束条件,通过数学的方法给出了考虑限位的碟簧初始压缩位移的解析表达式.基于MATLAB数值分析软件,建立了计算的数学模型,依据碟簧特定工况给出了碟簧初始压缩位移迭代求解的收敛准则,针对此数学模型编制了相应的求解程序,得到了求解工况下碟簧相关参数的详细数值.在综合考虑相关因素后得出了优化的碟簧初始压缩位移值.分析结果表明:碟簧各个计算所得的高度都呈非线性变化,且随着复合组合碟簧组数的增加,这些计算所得高度都随之增加,但鉴于成本、摩擦力及碟簧设计要求,碟簧设计参数应适当进行权衡择优,以满足工程设计需要.

关键词：限位碟簧初始压缩位移迭代求解

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of biomass co-pyrolysis and herbaceous plant colonization on the transformation of tailings into soil like substrate

引用

Journal of Environmental Sciences 2025年第1期147卷 230-243页

作者： Bin Zhu Meiyan Si Xin Xie Ximin yan Jianhong Huang Senlin Tian ping Ning Faculty of Environmental Science and Engineering Kunming University of Science and TechnologyKunming 650500China Guizhou Research Institute of Coal Mine Design Co. Ltd.Guiyang 550025China

Enhancing soil organic matter characteristics,ameliorating physical structure,mitigating heavy metal toxicity,and hastening mineral weathering processes are crucial approaches to accomplish the transition of tailings substrate to a soil-like *** incorporation of biomass co-pyrolysis and plant colonization has been established to be a significant factor in soil substrate formation and soil pollutant *** this,there is presently an absence of research efforts aimed at synergistically utilizing these two technologies to expedite the process of mining tailings soil substrate *** current study aimed to investigate the underlying mechanism of geochemical changes and rapid mineral weathering during the process of transforming tailings substrate into a soil-like substrate,under the combined effects of biomass co-smoldering pyrolysis and plant *** findings of this study suggest that the incorporation of smoldering pyrolysis and plant colonization induces a high-temperature effect and biological effects,which enhance the physical and chemical properties of tailings,while simultaneously accelerating the rate of mineral *** improvements include the amelioration of extreme pH levels,nutrient enrichment,the formation of aggregates,and an increase in enzyme activity,all of which collectively demonstrate the successful attainment of tailings substrate *** of the acceleratedweathering was verified by phase and surfacemorphology analysis using X-ray diffraction and scanning electron *** corrosion and fragmentation on the surface *** weathering resulted in corrosion and fragmentation of the surface of the treated *** study confirms that co-smoldering pyrolysis of biomass,combined with plant colonization,can effectively promote the transformation of tailings into soil-like *** method has can effectively address the key challenges that have previously hind

关键词： Smoldering Biomass co-pyrolysis Phytoremediation Soil-like substrate Tailing restoration

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ultrastructure of sperm in wild yak

引用

Journal of Agricultural Science and Technology 2008年第1期2卷 12-23页

作者： yan ping guo Xian LINJin-xing ZENG Yu-feng YAO Yu-ni LANG Xia Lanzhou Institute of Animal Science and Veterinary Pharmaceutics Chinese Academy of Agricultural Sciences Lanzhou 730050 China

The ultrastructure in sperm of wild yak can be used to examined and assess truly and all round the function and fertilization ability of the sperms. The ultrastructure in the sperm of wild yak was investigated under different states, such as fresh semen, frozen semen and capacitation sperm, and its characteristics were described by electron microscope. The sperm consisted of the head, neck and tail, the length was 78.34±7.24 μm. After capaeitation, the acrosome in sperm swelled and vesiculated, there were obvious vesicu]ation in the acrosome. The evagination on the ectoblast of acrosome formed the large vesiculation and inner membrane swelled. The evagination on the ectoblast of acrosome folded and tbrmed catenular vesiculation. The plasma membrane on the tail swelled. The head, neck and tail of the abnormal sperm were abnormal.

关键词： wild yak sperm ultrastructure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

支持敏捷制造的企业新型信息系统体系结构研究

引用

浙江大学学报（工学版） 2001年第1期35卷 77-82页

作者：林东豪高济严国平浙江大学计算机科学与工程学系浙江杭州310027

敏捷制造的成功实施要以信息服务在企业的全面渗透为基础 ,这就要求强化信息系统的开放性、可重用性和可伸缩性 .由此提出了一种支持敏捷制造的企业新型信息系统体系结构 ,并介绍了其各组成部分的工作机理和实现方法 .最后。

关键词：敏捷制造体系结构 Agent联邦本体论跨职能工作组供应链管理

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Constrained Networked Predictive Control for Nonlinear Systems Using a High-Order Fully Actuated System Approach

引用

IEEE/CAA Journal of Automatica Sinica 2025年第2期12卷 478-480页

作者： Yi Huang guo-ping Liu Yi Yu Wenshan Hu the School of Electrical Engineering and Automation Wuhan University IEEE the Center for Control Science and Technology Southern University of Science and Technology the Department of Electrical and Electronic Engineering The Hong Kong Polytechnic University

Dear Editor,In this letter, a constrained networked predictive control strategy is proposed for the optimal control problem of complex nonlinear highorder fully actuated (HOFA) systems with noises. The method can effectively deal with nonlinearities, constraints, and noises in the system, optimize the performance metric, and present an upper bound on the stable output of the system.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Metrological traceable calibration of organic carbon and elemental carbon based on laboratory-generated reference materials

引用

Journal of Environmental Sciences 2025年第3期149卷 524-534页

作者： Yue Liu Junjie Liu Ji Xiao Jing Ye Lixu guo Caiqing yan Center for Environmental Metrology National Institute of Metrology ChinaBeijing 100029China College of Chemistry and Chemical Engineering Taiyuan University of TechnologyTaiyuan 030024China Environment Research Institute Shandong UniversityQingdao 266237China

Carbonaceous aerosol,including organic carbon(OC)and elemental carbon(EC),has significant influence on human health,air quality and climate *** measurement of carbonaceous aerosol is essential to reduce the uncertainty of radiative forcing estimation and source *** accurate separation of OC and EC is controversial due to the charring of ***,the development of reference materials(RM)for the validation of OC/EC separation is an important basis for further *** RMs were mainly based on ambient air sampling,which could not provide traceability of OC and EC *** develop traceable RMs with known OC/EC contents,our study applied an improved aerosol generation and mixing technique,providing uniform deposition of particles on quartz *** generate OC aerosol with similar pyrolytic property of ambient aerosol,both water soluble organic carbon(WSOC)and water insoluble organic carbon(WIOC)were used,and amorphous carbon was selected for EC *** RMs were analyzed using different *** homogeneity within the filter was validated,reaching below 2%.The long-term stability of RMs has been validated with RSD ranged from 1.7%–3.2%.Good correlationwas observed between nominal concentration of RMswithmeasured concentration by two protocols,while the difference of EC concentration was within 20%.The results indicated that the newly developed RMs were acceptable for the calibration of OC and EC,which could improve the accuracy of carbonaceous aerosol ***,the laboratory-generated EC-RMs could be suitable for the calibration of equivalent BC concentration by Aethalometers.

关键词： Carbonaceous aerosol Split point Reference material Laboratory-generated Traceability

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：