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Both host and diet shape bacterial communities of predatory mites

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Insect Science 2024年第2期31卷 551-561页

作者： hong yan Endong wang Guo-Shu Wei Bo Zhang Xuenong Xu Institute of Plant Protection Chinese Academy of Agricultural SciencesBejingChina College of Plant Protection Hebei Agricultural UniversityBaodingHebei ProvinceChina Key Laboratory of Natural Enemies Insects Ministry of Agriculture and Rural AffairsBeijingChina

Microbial communities,derived from food,ambient,and inner,can affect host ecological adaption and *** with most phytophagous arthropods,predators may have more opportunities to develop specific microbiota depending on the level of prey *** explore how diet sources affect host microbial communities and vary across predator species,we considered 3 types of predators from Phytoseiidae(Acari:Mesostigmata):polyphagous(Amblyseius orientalis Ehara,Neoseiulus barkeri Hughes,and Amblyseius swirski Athias-Henrio),oligophagous(Neoseiulus californicus McGregor),and monophagous(Phytoseiulus persimilis Athias-Henriot)predatory *** polyphagous species were fed on 2 types of diets,natural prey and alternative *** using 16S rRNA sequencing,we found that diet was the main source of microbiota in predatory mites,while there was no clear pattern affected by prey *** 3 polyphagous predators,host species had a larger impact than prey on microbial *** *** or *** which showed consistency in their microbiota,prey switching significantly affectedβ-diversity of bacterial composition in ***,with 56%of the microbial *** short,our results confirmed the substantial influence of diet on host microbial construction in predatory species,and highlighted species differences in shaping the microbiota which are not necessarily related to prey specialization.

关键词： diet switching feeding habits host-microbial interactions invertebrate microbiota 16S rRNA

Significantly Enhanced Melt Memory Effect of Metallocene-made Isotactic Polypropylene Containing Talc

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Chinese Journal of Polymer Science 2024年第2期42卷 213-222,I0008页

作者： hong-Wen Sun Fu-Shan wang yan Gao Fu-Qing Wei Jia-Chun Feng State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular ScienceFudan UniversityShanghai200433China Lanzhou Petrochemical Corporation of PetroChina Lanzhou730060China Lanzhou Petrochemical Research Center Petrochemical Research Institute of PetroChinaLanzhou730060China

The melt memory effect is a widely observed phenomenon in semi-crystalline polymers. In practical applications, various additives are usually introduced into polymers, which may affect their melt memory behavior. In this work, the effect of talc on the melt memory effect of metallocene-made isotactic polypropylene(M-PP) was investigated in detail by using the differential scanning calorimetry. The results indicated that the introduction of talc significantly strengthened the melt memory effect of M-PP. Specifically, the upper limit temperature of Domain II increased from 161 ℃ to 174 ℃, resulting in a substantial widening of the temperature range of Domain IIa from 1 ℃ to 14 ℃. Analysis of the crystal orientation of the M-PP containing talc cooled from various Ts suggested that the remarkably enhanced melt memory effect could be ascribed to the stabilization of oriented nuclei facilitated by talc. This stabilizing effect was likely attributable to the prefreezing effect or the sorption interaction between talc and the M-PP chains.

关键词： Metallocene-made isotactic polypropylene Talc Melt memory effect Crystal orientation

Metal-organic framework IRMOFs coated with a temperaturesensitive gel delivering norcantharidin to treat liver cancer

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World Journal of Gastroenterology 2021年第26期27卷 4208-4220页

作者： Xiu-yan Li Qing-Xia Guan Yu-Zhou Shang yan-hong wang Shao-Wa Lv Zhi-Xin yang Rui wang Yu-Fei Feng Wei-Nan Li Yong-Ji Li College of Pharmacy Heilongjiang University of Chinese MedicineHarbin 150040Heilongjiang ProvinceChina

BACKGROUND Norcantharidin(NCTD)is suitable for the treatment of primary liver cancer,especially early and middle primary liver *** compound can reduce tumors and improve immune ***,the side effects of NCTD have limited its *** is a marked need to reduce the side effects and increase the efficacy of *** To develop a nanomaterial carrier,NCTD-loaded metal-organic framework IRMOF-3 coated with a temperature-sensitive gel(NCTD-IRMOF-3-Gel),aiming to improve the anticancer activity of NCTD and reduce the drug *** NCTD-IRMOF-3-Gel was obtained by a coordination *** apparent characteristics and in vitro release of NCTD-IRMOF-3-Gel were *** cytotoxicity assays,flow cytometry,and apoptosis experiments in mouse hepatoma(Hepa1-6)cells were used to determine the anti-liver cancer activity of NCTD-IRMOF-3-Gel in in vitro *** The particle size of NCTD-IRMOF-3-Gel was 50-100 nm,and the particle size distribution was *** release curve showed that NCTD-IRMOF-3-Gel had an obvious sustained-release *** cytotoxicity assays showed that the free drug NCTD and NCTD-IRMOF-3-Gel treatments markedly inhibited Hepa1-6 cell proliferation,and the inhibition rate increased with increasing drug *** flow cytometry,NCTD-IRMOF-3-Gel was observed to block the Hepa1-6 cell cycle in the S and G2/M phases,and the thermosensitive gel nanoparticles may inhibit cell proliferation by inducing cell cycle *** experiments showed that NCTD-IRMOF-3-Gel induced the apoptosis of Hepa1-6 *** Our results indicated that the NCTD-IRMOF-3-Gel may be beneficial for liver cancer disease treatment.

关键词： Norcantharidin Metal-organic frameworks IRMOF-3 Temperature-sensitive gel Drug delivery Liver cancer

Reliability of DC-link capacitor in pulsed power supply for accelerator magnet

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Nuclear Science and Techniques 2024年第9期35卷 28-40页

作者： Jie wang Da-Qing Gao Wan-Zeng Shen hong-Bin yan Li-Jun Mao Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology Lanzhou UniversityLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China

Capacitors are widely used in pulsed magnet power supplies to reduce ripple voltage,store energy,and decrease power *** this study,DC-link capacitors in pulsed power supplies were *** deriving an analytical method for the capacitor current on the H-bridge topology side,the root-mean-square value of the capacitor current was calculated,which helps in selecting the DC-link *** proposed method solves this problem quickly and with high *** current reconstruction of the DC-link capacitor is proposed to avoid structural damage in the capacitor’s current measurement,and the capacitor’s hotspot temperature and temperature rise are calculated using the FFT *** test results showed that the error between the calculated and measured temperature increases was within 1.5℃.Finally,the lifetime of DC-link capacitors was predicted based on Monte Carlo *** proposed method can evaluate the reliability of DC-link capacitors in a non-isolated switching pulsed power supply for accelerators and is also applicable to film capacitors.

关键词： Aluminum electrolytic capacitor DC-link current DC–DC power converter Hotspot temperature

Low Concentration of Wenyang Tonglin Decoction Promotes Conjugation and Transfer of Drug-Resistant Plasmids among Heterologous Strains

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Chinese Journal of Integrative Medicine 2024年第8期30卷 721-728页

作者： wang Bi-yan BU hong-shi XIA Li-bo JIANG Xiang-yu TONG yan-qing Department of Traditional Chinese Medicine Changchun University of Traditional Chinese MedicineChangchun130000China

Objective To investigate the effect of low concentration of Wenyang Tonglin Decoction(WTD)on the binding conditions of R45 plasmid conjugative transfer under liquid phase conjugation and its *** Escherichia coli CP9(R45)and Staphylococcus aureus RN450RF were cultured in medium containing WTD,and their minimum inhibitory concentration(MIC)values were *** promoter fusion technology,*** CP9(R45)containing a promoter fusion was obtained.β-Galactosidase activity of TrfAp and TrbBp was tested,and the mRNA expression of regulatory factors(TrbA,KorA,and KorB)was detected by real-time fluorescent quantitative polymerase chain *** The MIC of *** CP9(R45)was 400 g/L and that of *** RN450RF was 200 g/*** the drug concentration in the culture medium was 200 g/L,the highest number of conjugants was(3.47±0.20)×10^(7) CFU/mL At 90 h of conjugation,the maximum number of conjugants was(1.15±0.06)×10^(8) CFU/mL When the initial bacterial concentration was 10^(8) CFU/mL,the maximum number of conjugants was(3.47±0.20)×10^(7) CFU/*** the drug concentration was 200 g/L,theβ-galactosidase activity of TrfAp and TrbBp significantly increased;the relative quantification of TrbA,KorA and KorB were significantly *** Low concentration of WTD promoted the development of bacterial resistance by affecting promoters and inhibiting the expression of regulatory factors.

关键词： urinary tract infection Chinese medicine drug-resistant plasmid heterozygous strains conjugation transfer

A method for establishing a bearing residual life prediction model for process enhancement equipment based on rotor imbalance response analysis

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Chinese Journal of Chemical Engineering 2024年第2期66卷 203-215页

作者： Feng wang Haoran Li Zhenghui Zhang yan Bai hong Yin Jing Bian National Foundation Research Laboratory of Fault Prevention and Control in Hazardous Chemicals Production System Engineering Research Center of Chemical Technology SafetyBeijing University of Chemical TechnologyBeijing 100029China China Nuclear Power Engineering Co. LtdBeijing 100840China CNOOC Tianjin Chemical Research and Design Institute Co. LtdTianjin Key Laboratory of Energy and Chemical Explosion SafetyAcademician Expert Collaborative Innovation CenterTianjin 300131China

A rotating packed bed is a typical chemical process enhancement equipment that can strengthen micromixing and mass *** the operation of the rotating packed bed,the nonreactants and products irregularly adhere to the wire mesh packing in the rotor,thus resulting in an imbalance in the vibration of the rotor,which may cause serious damage to the bearing and material *** study proposes a model prediction for estimating the bearing residual life of a rotating packed bed based on rotor imbalance response *** method is used to determine the influence of the mass on the imbalance in the vibration of the rotor on bearing *** major influence on rotor vibration was found to be exerted by the imbalanced mass and its distribution radius,as revealed by the results of orthogonal *** implementing finite element analysis,the imbalance response curve for the rotating packed bed rotor was obtained,and a correlation among rotor imbalance mass,distribution radius of imbalance mass,and bearing residue life was established via data *** predicted value of the bearing life can be used as the reference basis for an early safety warning of a rotating packed bed to effectively avoid accidents.

关键词： Rotating packed bed Mass imbalance Harmonic response analysis Residual life Prediction model

Out-of-pocket payments and economic consequences from tuberculosis care in eastern China:income inequality

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Infectious Diseases of Poverty 2020年第1期9卷 26-35页

作者： yan Liu Cai-hong Xu Xiao-Mo wang Zhen-Yu wang yan-hong wang Hui Zhang Li wang Department of Epidemiology and Biostatistics Institute of Basic Medical Sciences Chinese Academy of Medical SciencesSchool of Basic Medicine Peking Union Medical CollegeBeijing 100005China Department of Critical Care Medicine The Second People’s Hospital of Shenzhen&First Affiliated Hospital of Shenzhen UniversityHealth Science CenterShenzhen 518035China National Center for Tuberculosis Control and Prevention China Center for Disease ControlBeijing 100226China

Background:Despite the availability of free tuberculosis(TB)diagnosis and treatment,TB care still generates substantial costs that push people into *** investigated out-of-pocket(OOP)payments for TB care and assessed the resulting economic burden and economic consequences for those with varying levels of household income in eastern ***:A cross-sectional study was conducted among TB patients in the national TB programme networks in eastern ***-related direct OOP costs,time loss,and coping strategies were investigated across households in different economic *** of Variance was used to examine the differences in various costs,and Kruskal-Wallis tests were used to compare the difference in total costs as a percentage of annual household ***:Among 435 patients,the mean OOP total costs of TB care were USD *** the lower-income quartile,OOP payments were lower,but costs as a percentage of reported annual household income were *** costs and costs prior to treatment accounted for 66.4 and 48.9%of the total costs,*** lower the household income was,the higher the proportion of medical costs to total costs before TB treatment,but the lower the proportion of medical costs patients spent in the intensive *** care caused 25.8%of TB-affected households to fall below the poverty line and caused the poverty gap(PG)to increase by United States Dollar(USD)*** in the poorest households had the highest poverty headcount ratio(70.2%)and PG(USD 236.1),but those in moderately poor households had the largest increase in the poverty headcount ratio(36.2%)and PG(USD 177.8)due to TB *** from poor households were more likely to borrow money to cope with the costs of TB care;however,there were fewer social consequences,except for food insecurity,in poor ***:Medical and pretreatment costs lead to high costs of TB care,especially among patients from the poorest *** is nec

关键词： Out-of-pocket payment Tuberculosis Impoverishment Coping strategy Eastern China

Cardiac involvement in light chain amyloidosis: a case report

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Journal of Geriatric Cardiology 2020年第6期17卷 373-378页

作者： Jing LI hong-yan wang Ning BIAN Ru-Yi XU Can HUA Shao-Li NIU Zhuo-Kun GAN Qing wang Hai-Tao TIAN VIP Cardiovascular Department the Sixth Medical Center of Chinese PLA General Hospital

Amyloidosis refers to a group of heterogeneous diseases in which amyloid fibers deposited in organ and extracellular tissue comprise misfolded precursor proteins.[1] According to the variety of misfolded proteins, the site of production and the type of tissue infiltrated, amyloidosis of the myocardium is divided into five subtypes: immunoglobulin light chain(AL), secondary amyloidosis(or reactive amyloido-

关键词： Arrhythmias Cardiac amyloidosis Diagnosis Immunoglobulin light chains Thromboembolism

The effects of biodiversity gradient on plant mass and metabolism of individual submerged macrophytes

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Ecological Processes 2021年第1期10卷 500-509页

作者： Liang-Yu Qi hong-Yuan Zeng Zhong-Xi Bai yan-hong wang Li Liu Wen Zhong Shi-Yun Ye Hui Fu Feng Li Chang-Liang Shao Ai-Ping Wu Ecology Department College of Resources&EnvironmentHunan Provincial Key Laboratory of Rural Ecosystem Health in Dongting Lake AreaHunan Agricultural UniversityChangsha 410128China. School of Forestry and Bio-technology Zhejiang Agriculture and Forestry UniversityHangzhou 311300China. CAS Key Laboratory of Agro-ecological Processes in Subtropical RegionInstitute of Subtropical AgricultureChangsha 410128China. National Hulunber Grassland Ecosystem Observation and Research Station&Institute of Agricultural Resources and Regional Planning Chinese Academy of Agricultural SciencesBeijing 100081China.

Background:The effects of biodiversity on community function and services are frequently studied in the history of ecology,while the response of individual species to biodiversity remains great *** this study,we determined the biodiversity effects on community productivity as well as species level plant mass and carbon(C)and nitrogen(N)metabolism of eight submerged *** macrophytes in Lake Erhai were selected and planted in a water depth of one meter along a diversity gradient of 1,2,4 or 8 ***,the community productivity or species level plant mass,soluble protein,free amino acid and soluble carbohydrate were correlated to species richness to determine the biodiversity effects on community and single ***:The results showed that the community level biomass was positively correlated to plant species richness although the species level plant mass of individual species responded differently to the overall plant species ***,only one plant mass positively correlated to species richness and the others decreased or showed no significant correlation with the increase of species *** soluble proteins of most macrophytes were positively correlated to species richness;however,both the free amino acid and soluble carbohydrate of the plants were negatively or not significantly correlated to species ***:These results indicated that the selection effects might dominate in our aquatic communities and the negative impacts of biodiversity on C and N metabolism of the macrophytes increased with the increase of species richness,which might result from the strong competition among the studied *** biodiversity effects on the plant mass,and C and N metabolism of individual submerged species were first reported in this study,while more such field and control experiments deserve further research.

关键词： Species richness Productivity Competition Submerged macrophyte Metabolism Biodiversity