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Contamination assessment,source apportionment and associated health risks of PTEs in agricultural soil under five land-use patterns in Sanya,China

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China Geology 2024年第3期7卷 469-479页

作者： Jian-zhou yang yan-gang fu Qiu-li Gong Sheng-ming Ma Jing-jing Gong Jian-weng Gao Zhen-liang Wang Yong-wen Cai Shi-xin Tang Institute of Geophysical and Geochemical Exploration Chinese Academy of Geological SciencesChina Geological SurveyLangfang 065000China Key Laboratory of Coupling Process and Effect of Natural Resources Elements Ministry of Natural ResourcesBeijing 100055China

To understand the levels of potentially toxic elements(PTEs)contamination in soils and their effects on human health from different agricultural land use in Sanya,China.128 soil samples(64 topsoil samples and corresponding subsoil samples)were collected from the five representative land-use *** coupled plasma mass spectrometry(ICP-MS),Atomic fluorescence spectrometry(AFS),and Inductively coupled plasma optical emission spectrometry(ICP-OES)were used to determine the content of PTEs(As,Cd,Hg,Cu,Cr,Ni,Pb,Zn,Co,Mo,Sb,and V).Correlation analysis and factor analysis were used to determine the source of ***-accumulation index(I_(geo)),hazard quotient(HQ),and total carcinogenic risk index(TR)were used to measure the PTEs contamination and its relative health *** showed that the average values of 12 PTEs in topsoil were higher than the Hainan soil geochemical baseline,showing different degrees of PTEs accumulation *** concentration of PTEs in the topsoil was lower than those in the subsoil except for Cd and *** I_(geo)revealed that the major accumulated element in soils was As followed by *** apportionment suggested that parent materials and agricultural practices were the dominant factors for PTEs accumulation in the *** risks of soil samples from five land-use patterns presented a trend of paddy field>dry field>woodland>orchard>garden ***,the HQ values of 12 PTEs were less than the recommended limit of HQ=1,representing that there are no non-carcinogenic risks of PTEs for children and adults in the study *** TR values are within 6.95×10^(-6)-1.38×10^(-5),which corresponds to the low *** the PTEs in the agricultural soil of the study area show little influence on the health status of the local population.

关键词： Potentially toxic trace elements(PTEs) Soils Land-use Geo-accumulation index(Igeo) Hazard quotient(HQ) Total carcinogenic risk index(TR) Source apportionment Health risk Agricutural geological survey engineering

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MADDPG-D2: An Intelligent Dynamic Task Allocation Algorithm Based on Multi-Agent Architecture Driven by Prior Knowledge

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Computer Modeling in Engineering & Sciences 2024年第9期140卷 2559-2586页

作者： Tengda Li gang Wang Qiang fu College of Air and Missile Defense Air Force Engineering UniversityXi’an710051China

Aiming at the problems of low solution accuracy and high decision pressure when facing large-scale dynamic task allocation(DTA)and high-dimensional decision space with single agent,this paper combines the deep reinforce-ment learning(DRL)theory and an improved Multi-Agent Deep Deterministic Policy Gradient(MADDPG-D2)algorithm with a dual experience replay pool and a dual noise based on multi-agent architecture is proposed to improve the efficiency of *** algorithm is based on the traditional Multi-Agent Deep Deterministic Policy Gradient(MADDPG)algorithm,and considers the introduction of a double noise mechanism to increase the action exploration space in the early stage of the algorithm,and the introduction of a double experience pool to improve the data utilization rate;at the same time,in order to accelerate the training speed and efficiency of the agents,and to solve the cold-start problem of the training,the a priori knowledge technology is applied to the training of the ***,the MADDPG-D2 algorithm is compared and analyzed based on the digital battlefield of ground and air *** experimental results show that the agents trained by the MADDPG-D2 algorithm have higher win rates and average rewards,can utilize the resources more reasonably,and better solve the problem of the traditional single agent algorithms facing the difficulty of solving the problem in the high-dimensional decision *** MADDPG-D2 algorithm based on multi-agent architecture proposed in this paper has certain superiority and rationality in DTA.

关键词： Deep reinforcement learning dynamic task allocation intelligent decision-making multi-agent system MADDPG-D2 algorithm

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Neurokinin-2 receptor antagonist SR48968 induced necroptosis of myeloid leukemia cells by calcium overload-driven reactive oxygen species accumulation

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Genes & Diseases 2024年第5期11卷 33-35页

作者： Zhibin yan Xiangyu Hong Qihao Lin Leijie Wang gang Shao Chentao Ge Ruilong Xia Caiyun fu Zhejiang Provincial Key Laboratory of Silkworm Bioreactor and Biomedicine College of Life Sciences and MedicineZhejiang Sci-Tech UniversityHangzhouZhejiang 310018China College of Life Sciences China Jiliang UniversityHangzhouZhejiang 310018China

Increasing evidence highlight tachykinin receptors as a prominent player in hematological *** previously revealed the proto-oncogenic role of neurokinin-1 receptor(NK-1R)in acute myeloid leukemia(AML),1 whereas the role of neurokinin-2 receptor(NK-2R)has not been ***,we found NK-2R was significantly up-regulated in AML patients in The Cancer Genome Atlas *** result was further confirmed in blood from AML patients and a range of human leukemia ***,we verified that blocking NK-2R by SR48968 markedly promoted cell death in human myeloid leukemia without cytotoxicity to normal ***,we uncovered that SR48968 induced cytotoxicity through necroptosis mediated by calcium overload-driven reactive oxygen species(ROS)*** summary,our results propose that NK-2R antagonist SR48968 may be used as a new therapeutic approach for myeloid leukemia.

关键词： myeloid antagonist markedly

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Myosteatosis is associated with coronary artery calcification in patients with type 2 diabetes

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World Journal of Diabetes 2024年第3期15卷 429-439页

作者： fu-Peng Liu Mu-Jie Guo Qing yang yan-Ying Li yan-gang Wang Mei Zhang The Affiliated Hospital of Medical College Qingdao University Qingdao UniversityQingdao 266071Shandong ProvinceChina Department of Endocrinology The Affiliated Hospital of Jining Medical UniversityJining 272029Shandong ProvinceChina Department of Medical Imaging The Affiliated Hospital of Jining Medical UniversityJining 272029Shandong ProvinceChina Department of Clinical Nutrition The Affiliated Hospital of Jining Medical UniversityJining 272029Shandong ProvinceChina Department of Endocrinology The Affiliated Hospital of Qingdao UniversityQingdao 266003Shandong ProvinceChina

BACKGROUND Myosteatosis,rather than low muscle mass,is the primary etiologic factor of sarcopenia in patients with type 2 diabetes mellitus(T2DM).Myosteatosis may lead to a series of metabolic dysfunctions,such as insulin resistance,systematic inflammation,and oxidative stress,and all these dysfunctions are closely associated with the acceleration of T2DM and *** To investigate the association between myosteatosis and coronary artery calcification(CAC)in patients with *** Patients with T2DM,who had not experienced major cardiovascular events and had undergone both abdominal and thoracic computed tomography(CT)scans,were *** mean skeletal muscle attenuation was assessed using abdominal CT images at the L3 *** CAC score was determined from thoracic CT images using the Agatston scoring *** was diagnosed according to Martin’s *** CAC(SCAC)was defined when the CAC score exceeded *** regression and decision tree analyses were *** A total of 652 patients with T2DM were *** them,167(25.6%)patients had *** regression analysis demonstrated that myosteatosis,age,duration of diabetes,cigarette smoking,and alcohol consumption were independent risk factors of *** was significantly associated with an increased risk of SCAC(OR=2.381,P=0.003).The association between myosteatosis and SCAC was significant in the younger patients(OR=2.672,95%CI:1.477-4.834,P=0.002),but not the older patients(OR=1.456,95%CI:0.863-2.455,P=0.188),and was more prominent in the population with lower risks of *** decision tree analyses prioritized older age as the primary variable for *** older patients,cigarette smoking was the main contributing factor for SCAC,while in younger patients,it was *** Myosteatosis is a novel risk factor for atherosclerosis in patients with T2DM,especially in the population with younger ages and fewer traditional ri

关键词： Type 2 diabetes Myosteatosis Muscle quality Coronary artery calcification Atherosclerosis Cardiovascular diseases

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Energy absorption behaviors of a novel buffer lander-leg with Yoshimura core

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Chinese Journal of Aeronautics 2024年第4期37卷 333-342页

作者： yan XU He HUANG Chao ZHANG Rongji fu School of Aeronautics and Astronautics Zhejiang UniversityHangzhou 310027China School of Mechanics Civil Engineering and Architecture Northwestern Polytechnical UniversityXi’an 710072China

In the current soft-landing system,the lander-leg and the buffer are two independent parts which may cause weight *** traditional mechanical buffers also have their own shortcomings such as small buffer stroke and being non-reusable.A Novel Buffer Lander-leg with Yoshimura core (NBLY) is proposed in this paper,inspired by the Buckling Restrained Brace(BRB).The design details of NBLY and parameter definitions of the core are *** finite element analysis modes have been employed to analyze the nonlinear mechanical behaviors of NBLY subjected to the cyclic *** with four different core styles of hexagon,octagon,dodecagon and hexadecagon are analyzed and *** restraining ratio and cumulative dissipation energy ratio have been obtained to evaluate the energy absorption *** results show that the origami pattern has significant influences on the deformation ductility,plastic energy absorbing and axial load transferring to the *** NBLY with octagon core has outstanding properties,especially the hysteretic energy dissipation and enhancement of compression *** interaction mechanism between the core and encasing member constrains the deformation extensions and contributes to the frictional energy dissipation of the *** paper provides a new conceptual design of buffer lander-leg for soft-landing *** can realize the reuse function as a buffer lander-leg with better loading-bearing and energy absorption behaviors.

关键词： Lander-leg structure Origami Energy absorption Cyclic loading Finite element analysis

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Significantly Enhanced Melt Memory Effect of Metallocene-made Isotactic Polypropylene Containing Talc

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Chinese Journal of Polymer Science 2024年第2期42卷 213-222,I0008页

作者： Hong-Wen Sun fu-Shan Wang yan Gao fu-Qing Wei Jia-Chun Feng State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular ScienceFudan UniversityShanghai200433China Lanzhou Petrochemical Corporation of PetroChina Lanzhou730060China Lanzhou Petrochemical Research Center Petrochemical Research Institute of PetroChinaLanzhou730060China

The melt memory effect is a widely observed phenomenon in semi-crystalline polymers. In practical applications, various additives are usually introduced into polymers, which may affect their melt memory behavior. In this work, the effect of talc on the melt memory effect of metallocene-made isotactic polypropylene(M-PP) was investigated in detail by using the differential scanning calorimetry. The results indicated that the introduction of talc significantly strengthened the melt memory effect of M-PP. Specifically, the upper limit temperature of Domain II increased from 161 ℃ to 174 ℃, resulting in a substantial widening of the temperature range of Domain IIa from 1 ℃ to 14 ℃. Analysis of the crystal orientation of the M-PP containing talc cooled from various Ts suggested that the remarkably enhanced melt memory effect could be ascribed to the stabilization of oriented nuclei facilitated by talc. This stabilizing effect was likely attributable to the prefreezing effect or the sorption interaction between talc and the M-PP chains.

关键词： Metallocene-made isotactic polypropylene Talc Melt memory effect Crystal orientation

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How interfacial electron-donating defects influence the structure and charge of gold nanoparticles on TiO_(2)support

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Nano Research 2024年第7期17卷 5965-5974页

作者： Guang-Jie Xia Yu fu Wei Cao Jun Li yang-gang Wang Department of Chemistry and Guangdong Provincial Key Laboratory of Catalysis Southern University of Science and TechnologyShenzhen 518055China School of Physical Sciences Great Bay UniversityDongguan 523000China Department of Chemistry Tsinghua UniversityBeijing 100084China

The reduction degree of TiO_(2)support is critical to the performances of metal *** many previous theoretical calculations,only the bridge oxygen vacancy(Ov)was considered as the electron-donating defect on reduced rutile TiO_(2)(r-TiO_(2−x))***,titanium adatoms(Tiad.),oxidized titanium islands(***),and acid hydroxyls(ObrH)also exist at the metal/support *** conducting density functional theory(DFT)calculations and ab initio molecular dynamics(AIMD)simulations,we compared r-TiO_(2−x)surfaces with Ov,Tiad.,***,and ObrH sites loaded with Au nanoparticles(NPs).The results showed the Au NPs were oxygen-phobic but titanium-philic,resulting in wetting of Ov and *** short contact with *** and *** Bader charges of Au NPs(QM)showed a good linear relationship with the ideal number of donating electrons(Ne)from the defective sites(QM=−KeNe+QM,S),demonstrating the intrinsic electron allocation at the *** Ov,Tiad.,and *** exhibited similar slopes(Ke),relatively steeper than that of *** means in the scope of Au NP charge state,the *** *** have a close electron-donating ability with Ov,but the ObrH donates relatively fewer *** linear relationship can be extended approximately to other *** higher the metal work function,the steeper the Ke for easier electron donation from defective *** stronger the metal oxygen affinity,the more positive the intercept(QM,S).That explains the easy generation of metallic or negative Pt and Au NPs on r-TiO_(2−x),but hard for Cu and Zn in *** provides theoretical guidance for regulating the charge of metal NPs over TiO_(2−x)supports.

关键词： metal-support interaction titanium oxide oxygen vacancy surface hydroxyl titanium adatom

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Efficacy of scraping therapy on blood pressure and sleep quality in stage Ⅰ and Ⅱ essential hypertension: A systematic review and meta-analysis

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Journal of Integrative Medicine 2024年第1期22卷 12-21页

作者： Zheng-gang Zhu Jian-ru Wang Xiao-yan Pan School of Nursing Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina School of Health Sciences Universiti Sains MalaysiaKubang Kerian 16150KelantanMalaysia Department of Cardiovascular Medicine the First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou 450000Henan ProvinceChina

Background Scraping therapy is widely used in treating stage I and II essential hypertension in ***,there has been no systematic evaluation of the efficacy of scraping therapy on blood pressure and sleep quality in stage I and II essential *** strategy Seven electronic databases(PubMed,Scopus,Cochrane Library,Web of Science,EBSCO,China National Knowledge Infrastructure and Wanfang Data electronic databases)were searched from inception to December *** on the principle of combining subject words with text words,the search strategy was constructed around search terms for“scraping therapy,”“scraping,”“Guasha,”“Gua sha,”“hypertension,”and“high blood pressure”during the database *** criteria Randomized controlled trials(RCTs)were included if they recruited patients with stage I and II essential hypertension and included a scraping therapy *** intervention group received antihypertensive drugs and scraping therapy,while the control group only took antihypertensive *** extraction and analysis Review Manager 5.4.0 and STATA 15.1 were used to enter all the relevant outcome variables to conduct the *** quality of the selected RCTs was assessed using the PEDro *** sensitivity analysis was carried out by iteratively excluding individual studies and repeating the analysis to determine the stability of the findings and identify any studies with greater influence on the *** analysis was performed to find the source of *** plots were used to evaluate the publication bias of included *** Nine RCTs including 765 participants were ***-analysis showed that scraping therapy combined with medication had an advantage over the use of medication alone in lowering systolic blood pressure(mean difference[MD]=?5.09,95%confidence interval[CI]=?6.50 to?3.67,P<0.001)and diastolic blood pressure(MD=?2.66,95%CI=?3.17 to?2.14,P<0.001).Subgroup analysis showed tha

关键词： Scraping therapy Essential hypertension Efficacy Blood pressure Sleep quality Systematic review Meta-analysis

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Comparison of Rotating Stall Warning by Different Methods for Variable Speed Configurations in a Contra-Rotating Compressor

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Journal of Thermal Science 2024年第4期33卷 1379-1393页

作者： XUE Fei WANG yan'gang LIU Qian WU Tong LIU Hanru School of Power and Energy Northwestern Polytechnical UniversityXi’an710072China

Stall in compressors can cause performance degradation and even lead to *** unacceptable consequences can be avoided by timely monitoring stall inception and taking effective *** paper focused on the rotating stall warning in a low-speed axial contra-rotating ***,the stall disturbance characteristics under different speed configurations were *** results showed that as the speed ratio(RR)increased,the stall disturbance propagation speed based on the rear rotor speed gradually ***,the standard deviation(SD)method,the cross-correlation(CC)method,and the discrete wavelet transform(DWT)method were employed to obtain the stall initiation moments of three different speed *** was found that the SD and CC methods did not achieve significant stall warning results in all three speed ***,the stall initiation moment obtained by the DWT method at RR=1.125 was one period after the stall had fully developed,which was ***,a stall warning method was developed in the present work based on the long short-term memory(LSTM)regression *** applying the LSTM model,the predicted stall initiation moments of three speed configurations were at the 557th,518th,and 333rd revolution,which were44,2,and 74 revolutions ahead of stall onset moments,***,in scenarios where a minor disturbance preceded the stall,the stall warning effect of the LSTM was greatly improved in comparison with the aforementioned three *** contrast,when the pressure fluctuation before the stall was relatively small,the differences between the stall initiation moments predicted by these four methods were not significant.

关键词： contra-rotating compressor stall disturbance stall initiation moment long short-term memory(LSTM) stall warning

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Nanocrystalline WSe_(2)excels at high-performance anode for Na storage via a facile one-pot hydrothermal method

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Tungsten 2024年第1期6卷 248-258页

作者： Hai-yan Zou Lei Fang gang Yu Dong Wang State Key Laboratory of Chem/Bio-Sensing and Chemometrics Provincial Hunan Key Laboratory for Graphene Materials and DevicesCollege of Chemistry and Chemical EngineeringHunan UniversityChangsha 410082China Changxing County Quality and Technology Supervision and Testing Center Huzhou 313100China

For the next large-scale energy storage systems,sodium-ion batteries(SIBs)with excellent electrochemical performance are ***,the exploration of anode materials with high specific capacity,fascinating cycling stability and rate capability is still *** transition metal dichalcogenides(TMDs),tungsten diselenide(WSe_(2))has been regarded as an effective anode material for SIBs and has been extensively studied,due to high theoretical capacity and unique twodimensional layered ***,nanocrystalline WSe_(2)is prepared by a facile one-pot hydrothermal *** with the micro-scale WSe_(2),benefiting from the high specific surface area of highly ordered nano-flake structures and short ion/electron transport paths,nanocrystalline WSe_(2)shows excellent electrochemical performance in Na *** 1000 cycles at a current density of 2 A·g^(-1),a high specific capacity of 264.4 mA·h·g^(-1)is still *** full cell matched with the Na_(3)V_(2)(PO_(4))_(3) cathode can deliver an excellent reversible specific capacity of 196.5 mA·h·g^(-1)after 100 cycles at 0.5 A·g^(-1).

关键词： Tungsten diselenide Transition metal dichalcogenides Hydrothermal Sodium-ion batteries Layered structure

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