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Chinese Physics B 2021年第6期30卷 617-624页

作者： Yao Wang Sheng-Wang Yu yan-Peng Xue Hong-Jun Hei yan-xia wu yan-yan Shen Institute of New Carbon Materials Taiyuan University of TechnologyTaiyuan 030024China National Center for Materials Service Safety University of Science and Technology BeijingBeijing 100083China

Nano-diamond particles are co-deposited on Ti substrates with metal(Ti/Ni) nanoparticles(NPs) by the electrophoretic deposition(EPD) method combined with a furnace annealing at 800℃ under N_(2) atmosphere. Modifications of structural and electron field emission(EFE) properties of the metal-doped films are investigated with different metal NPs concentrations. Our results show that the surface characteristics and EFE performances of the samples are first enhanced and then reduced with metal NPs concentration increasing. Both the Ti-doped and Ni-doped nano-diamond composite films exhibit optimal EFE and microstructural performances when the doping quantity is 5 mg. Remarkably enhanced EFE properties with a low turn-on field of 1.38 V/μm and a high current density of 1.32 mA/cm^(2) at an applied field of 2.94 V/μm are achieved for Ni-doped nano-diamond films, and are superior to those for Ti-doped ones. The enhancement of the EFE properties for the Ti-doped films results from the formation of the TiC-network after annealing. However, the doping of electron-rich Ni NPs and formation of high conductive graphitic phase are considered to be the factor, which results in marvelous EFE properties for these Ni-doped nano-diamond films.

关键词： diamond films metal doping electrophoretic deposition field emission properties

Direct chemical vapor deposition growth of graphene on Ni particles using solid carbon sources

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Rare Metals 2021年第8期40卷 2275-2280页

作者： Feng Zheng Ying Liu Cai-Li Zhang Jian Wang Nan Dong Pei-De Han yan-xia wu Yu-Cheng wu College of Materials Science and Engineering Taiyuan University of TechnologyTaiyuan030024China Institute of New Carbon Materials Taiyuan University of TechnologyTaiyuan030024China

Graphene has attained a considerable amount of popularity as an attractive ultra-thin reinforcement for nickel(Ni)matrix composites in recent ***,its excellent reinforcement efficiency is suffered from the agglomeration of graphene nanosheets in manufacturing process and the poor bonding strength of graphene with Ni *** overcome these two problems,one of the efficient strategies is to in-situ grow graphene reinforcements on Ni particles for powder *** work aims to synthesize uniform graphene@Ni composite particles by using polymethyl methacrylate(PMMA)as the solid sources for chemical vapor deposition(CVD)*** results demonstrate that few-layer or multilayer graphene with different morphologies can be grown on the particles by controlling the PMMA content and annealed temperature,*** optimum condition for the formation of high-quality few-layer graphene is 1.0 mg·ml^(-1) PMMA and 900℃.A competition mechanism rises from the growth kinetic,and the spatial confinement effect has led to the formation of graphene with different microstructures and morphologies.

关键词： Graphene Ni particles Solid carbon sources Growth mechanism

Syntheses and Crystal Structures of Two Coordination Polymers with Aromatic Dioxide as Bridge Ligands

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Chinese Journal of Structural Chemistry 2007年第2期26卷 214-218页

作者： SHI Jing-Min XU Hai-yan ZHANG Feng-xia wu Chang-Ju LIU Lian-Dong Department of Chemistry Shandong Normal University Jinan 250014 China

Two coordination polymers, namely, two-dimensional complex 1 {[Cu（μ- L）1.5（ClO4）2（H2O）].（H2O）0.5]n （L = pyrazine-1,4-dioxide） and one-dimensional complex 2 [Co（μ-L）Br2（H2O）2]n, have been synthesized with pyrazine-1,4-dioxide as bridging ligands, and their crystal structures were determined by X-ray crystallography. Crystal data for complex 1： monoclinic system, space group C2/c, with a = 23.310（3）, b = 12.2338（17）, c = 10.6075（15） A, β= 110.487（2）°, V = 2833.6（7） A3, Z = 8, C6H9C12CuN3O12.5, Mr = 457.60, Dc = 2.145 g/cm^3, F（000） = 1832 and μ = 1.998 mm^-1; and those for 2： monoclinic system, space group C2/c, with a = 11.012（3）, b = 7.483（2）, c = 11.451（3） A, β = 101.654（4）°, V = 924.2（4） A3, Z = 4, C4HsBr2CoN2O4, Mr = 366.87, Dc = 2.637 g/cm^3, F（000） = 700 and μ = 10.487 mm^-1. 1 shows a two-dimensional sheet structure on the ac plane through the coordination of μ-L bridging ligands with Cu（Ⅱ） ions, while 2 displays a zigzag one-dimensional chain along the c axis via the coordination of μ-L bridging ligand with Co（Ⅱ） ions. Hydrogen bonds in 1 and 2 make the sheets （or chains） connect each other to form a three-dimensional structure.

关键词： Aromatic Dioxide coordination polymers Hydrogen bonds

Retinal ischemia-reperfusion injury and pretreatment with Lycium barbarum glycopeptide

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International Journal of Ophthalmology(English edition) 2024年第9期17卷 1599-1605页

作者： yan-xia wu Shuo Yin Shan-Shan Song xiang Liu Yu-Xuan Deng Xue-Jing Lu Eye School of Chengdu University of Traditional Chinese Medicine Chengdu 610075Sichuan ProvinceChina Ineye Hospital of Chengdu University of Traditional Chinese Medicine Chengdu 610084Sichuan ProvinceChina School of Chinese Classics Chengdu University of Traditional Chinese MedicineChengdu 610075Sichuan ProvinceChina Key Laboratory of Sichuan Province Ophthalmopathy Prevention&Cure and Visual Function Protection with Traditional Chinese Medicine Chengdu 610075Sichuan ProvinceChina Retinal Image Technology and Chronic Vascular Disease Prevention&Control and Collaborative Innovation Center Chengdu 610075Sichuan ProvinceChina

AIM:To investigate the antioxidant protective effect of Lycium barbarum glycopeptide(LbGP)pretreatment on retinal ischemia-reperfusion(I/R)injury(RIRI)in ***:RIRI was induced in Sprague Dawley rats through anterior chamber perfusion,and pretreatment involved administering LbGP via gavage for *** 24h of reperfusion,serum alanine aminotransferase(ALT),aspartate aminotransferase(AST),and creatinine(CREA)levels,retinal structure,expression of Caspase-3 and Caspase-8,superoxide dismutase(SOD)activity,and malondialdehyde(MDA)in the retina were ***:The pretreatment with LbGP effectively protected the retina and retinal tissue from edema and inflammation in the ganglion cell layer(GCL)and nerve fiber layer(NFL)of rats subjected to RIRI,as shown by light microscopy and optical coherence tomography(OCT).Serum AST was higher in the model group than in the blank group(P=0.042),but no difference was found in ALT,AST,and CREA across the LbGP groups and model ***-3 expression was higher in the model group than in the blank group(P=0.006),but no difference was found among LbGP groups and the model ***-8 expression was higher in the model group than in the blank group(P=0.000),and lower in the 400 mg/kg LbGP group than in the model group(P=0.016).SOD activity was lower in the model group than in the blank group(P=0.001),and the decrease was slower in the 400 mg/kg LbGP group than in the model group(P=0.003).MDA content was higher in the model group than in the blank group(P=0.001),and lower in the 400 mg/kg LbGP group than in the model group(P=0.016).The pretreatment with LbGP did not result in any observed liver or renal toxicity in the ***:LbGP pretreatment exhibits dosedependent anti-inflammatory,and antioxidative effects by reducing Caspase-8 expression,preventing declines of SOD activity,and decreasing MDA content in the RIRI rat model.

关键词： retinal ischemia-reperfusion Lycium barbarum glycopeptide pretreatment anti-inflammatory antioxidative rat

Structure and tribological properties of Si/a-C:H(Ag)multilayer film in stimulated body fluid

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Chinese Physics B 2020年第11期29卷 412-419页

作者： yan-xia wu Yun-Lin Liu Ying Liu Bing Zhou Hong-Jun Hei Yong Ma Sheng-Wang Yu Yu-Cheng wu Institute of New Carbon Materials Taiyuan University of TechnologyTaiyuan 030024China Key Laboratory of Interface Science and Engineering in Advanced Materials(Taiyuan University of Technology) Ministry of EducationTaiyuan 030024China

Si/a-C:H(Ag)multilayer films with different modulation periods are prepared to test their potential applications in human *** composition,microstructure,mechanical and tribological properties in the simulated body fluid are *** results show the concentration of Ag first decreases and then increases with the modulation period decreasing from 984 nm to 250 *** the C content has an opposite variation ***,the concentration of Ag plays a more important role than the modulation period in the properties of the multilayer *** a-C:H sublayer of the film with an appropriate Ag concentration(8.97 at.%)(modulation period of 512 nm)maintains the highest sp3/sp2 ratio,surface roughness and hardness,and excellent tribological property in the stimulated body *** appropriate number of Ag atoms and size of Ag atom allow the Ag atoms to easily enter into the contact interface for load bearing and *** work proves that the Ag nanoparticles in the a-C:H sublayer plays a more important role in the tribological properties of the composite-multilayer film in stimulated body fluid condition.

关键词： Si/a-C:H(Ag)multilayer film modulation periods Ag concentration tribological properties

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三次透视投影变换图像拼接

光学精密工程 2015年第9期23卷 2724-2731页

作者：颜无瑕刘传才南京理工大学计算机科学与工程学院江苏南京210094

为了减少带有路面信息的建筑物图像的拼接中产生的图像失真并提高拼接速度,基于局部变形方法并结合建筑物和路面纹理信息的不同提出了三次投影变换图像拼接方法。该方法根据图像内容将图像分割成不同子图像,然后拼接图像内容相同的子图... 详细信息

为了减少带有路面信息的建筑物图像的拼接中产生的图像失真并提高拼接速度,基于局部变形方法并结合建筑物和路面纹理信息的不同提出了三次投影变换图像拼接方法。该方法根据图像内容将图像分割成不同子图像,然后拼接图像内容相同的子图像,最后实施总体拼接。为了改善当前全局投影变换带来的图像形状失真或扭曲问题,整个拼接过程采用三次局部的透视投影图像变换方法。由于是在传统的透视投影变换的基础上基于图像内容分割后再拼接,故拼接结果比传统方法更精确、更真实。实验结果表明：采用提出的图像拼接方法克服了路面部分纹理信息过少导致图像失真的缺陷,拼接速度比相关拼接方法提高了20%~40%。该方法能快速得到清晰无缝的拼接图像,基本满足拼接速度快、真实度高的要求。

关键词：图像分割图像拼接 Hough变换透视投影变换

Neuronal regulated cell death in aging-related neurodegenerative diseases:key pathways and therapeutic potentials

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Neural Regeneration Research 2025年第8期20卷 2245-2263页

作者： Run Song Shiyi Yin Jiannan wu Junqiang yan Department of Neurology The First Affiliated HospitalCollege of Clinical Medicine of Henan University of Science and TechnologyLuoyangHenan ProvinceChina Neuromolecular Biology Laboratory The First Affiliated HospitalCollege of Clinical Medicine of Henan University of Science and TechnologyLuoyangHenan ProvinceChina

Regulated cell death(such as apoptosis,necroptosis,pyroptosis,autophagy,cuproptosis,ferroptosis,disulfidptosis)involves complex signaling pathways and molecular effectors,and has been proven to be an important regulatory mechanism for regulating neuronal aging and ***,excessive activation of regulated cell death may lead to the progression of aging-related *** review summarizes recent advances in the understanding of seven forms of regulated cell death in age-related ***,the newly identified ferroptosis and cuproptosis have been implicated in the risk of cognitive impairment and neurodegenerative *** forms of cell death exacerbate disease progression by promoting inflammation,oxidative stress,and pathological protein *** review also provides an overview of key signaling pathways and crosstalk mechanisms among these regulated cell death forms,with a focus on ferroptosis,cuproptosis,and *** instance,FDX1 directly induces cuproptosis by regulating copper ion valency and dihydrolipoamide S-acetyltransferase aggregation,while copper mediates glutathione peroxidase 4 degradation,enhancing ferroptosis ***,inhibiting the Xc-transport system to prevent ferroptosis can increase disulfide formation and shift the NADP^(+)/NADPH ratio,transitioning ferroptosis to *** insights help to uncover the potential connections among these novel regulated cell death forms and differentiate them from traditional regulated cell death *** conclusion,identifying key targets and their crosstalk points among various regulated cell death pathways may aid in developing specific biomarkers to reverse the aging clock and treat age-related neurodegenerative conditions.

关键词： apoptosis autophagy cuproptosis disulfidptosis ferroptosis necroptosis neurodegenerative disease neurological aging diseases PANoptosis pyroptosis

Remaining Life Prediction Method for Photovoltaic Modules Based on Two-Stage Wiener Process

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Energy Engineering 2025年第1期122卷 331-347页

作者： Jie Lin Hongchi Shen Tingting Pei yan wu School of Electrical Engineering and Information Engineering Lanzhou University of TechnologyLanzhou730050China

Photovoltaic (PV) modules, as essential components of solar power generation systems, significantly influence unitpower generation *** service life of these modules directly affects these costs. Over time, the performanceof PV modules gradually declines due to internal degradation and external environmental *** cumulativedegradation impacts the overall reliability of photovoltaic power generation. This study addresses the complexdegradation process of PV modules by developing a two-stage Wiener process model. This approach accountsfor the distinct phases of degradation resulting from module aging and environmental influences. A powerdegradation model based on the two-stage Wiener process is constructed to describe individual differences inmodule degradation processes. To estimate the model parameters, a combination of the Expectation-Maximization(EM) algorithm and the Bayesian method is employed. Furthermore, the Schwarz Information Criterion (SIC) isutilized to identify critical change points in PV module degradation trajectories. To validate the universality andeffectiveness of the proposed method, a comparative analysis is conducted against other established life predictiontechniques for PV modules.

关键词： Photovoltaic modules degradation stochastic processes lifetime prediction

miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells

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Neural Regeneration Research 2025年第1期20卷 277-290页

作者： Meng Cong Jing-Jing Hu yan Yu xiao-Li Li xiao-Ting Sun Li-Ting Wang xia wu Ling-Jie Zhu xiao-Jia yang Qian-Ru He Fei Ding Hai-yan Shi School of Medicine Nantong UniversityNantongJiangsu ProvinceChina Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education and Coinnovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Physiology Jiangsu Health Vocational CollegeNanjingJiangsu ProvinceChina Department of Pathology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina

Our previous study found that rat bone marrow–derived neural crest cells(acting as Schwann cell progenitors)have the potential to promote long-distance nerve ***-based therapy can enhance peripheral nerve repair and regeneration through paracrine bioactive factors and intercellular ***,the complex contributions of various types of soluble cytokines and extracellular vesicle cargos to the secretome remain *** investigate the role of the secretome and extracellular vesicles in repairing damaged peripheral nerves,we collected conditioned culture medium from hypoxia-pretreated neural crest cells,and found that it significantly promoted the repair of sensory neurons damaged by oxygen-glucose *** mRNA expression of trophic factors was highly expressed in hypoxia-pretreated neural crest *** performed RNA sequencing and bioinformatics analysis and found that miR-21-5p was enriched in hypoxia-pretreated extracellular vesicles of neural crest ***,to further clarify the role of hypoxia-pretreated neural crest cell extracellular vesicles rich in miR-21-5p in axonal growth and regeneration of sensory neurons,we used a microfluidic axonal dissociation model of sensory neurons in vitro,and found that hypoxia-pretreated neural crest cell extracellular vesicles promoted axonal growth and regeneration of sensory neurons,which was greatly dependent on loaded ***,we constructed a miR-21-5p-loaded neural conduit to repair the sciatic nerve defect in rats and found that the motor and sensory functions of injured rat hind limb,as well as muscle tissue morphology of the hind limbs,were obviously *** findings suggest that hypoxia-pretreated neural crest extracellular vesicles are natural nanoparticles rich in ***-21-5p is one of the main contributors to promoting nerve regeneration by the neural crest cell *** helps to explain the mechanism of action of the secretome and e

关键词： axotomy cell-free therapy conditioned medium extracellular vesicles hypoxic preconditioning microRNA oxygen-glucose deprivation peripheral nerve injury Schwann cell precursors

Chondroitinase ABC combined with Schwann cell transplantation enhances restoration of neural connection and functional recovery following acute and chronic spinal cord injury

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Neural Regeneration Research 2025年第5期20卷 1467-1482页

作者： Wenrui Qu xiangbing wu Wei wu Ying Wang yan Sun Lingxiao Deng Melissa Walker Chen Chen Heqiao Dai Qi Han Ying Ding Yongzhi xia George Smith Rui Li Nai-Kui Liu xiao-Ming Xu Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteDepartment of Neurological SurgeryIndiana University School of MedicineIndianapolisINUSA Department of Hand Surgery the Second Hospital of Jilin UniversityChangchunJilin ProvinceChina Shriners Hospitals Pediatric Research Center Temple University School of MedicinePhiladelphiaPAUSA Department of Anatomy&Cell Biology Indiana University School of MedicineIndianapolisINUSA

Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties.A the Food and Drug Administration-approved Phase I clinical trial has been conducted to evaluate the safety of transplanted human autologous Schwann cells to treat patients with spinal cord injury.A major challenge for Schwann cell transplantation is that grafted Schwann cells are confined within the lesion cavity,and they do not migrate into the host environment due to the inhibitory barrier formed by injury-induced glial scar,thus limiting axonal reentry into the host spinal *** we introduce a combinatorial strategy by suppressing the inhibitory extracellular environment with injection of lentivirus-mediated transfection of chondroitinase ABC gene at the rostral and caudal borders of the lesion site and simultaneously leveraging the repair capacity of transplanted Schwann cells in adult rats following a mid-thoracic contusive spinal cord *** report that when the glial scar was degraded by chondroitinase ABC at the rostral and caudal lesion borders,Schwann cells migrated for considerable distances in both rostral and caudal *** Schwann cell migration led to enhanced axonal regrowth,including the serotonergic and dopaminergic axons originating from supraspinal regions,and promoted recovery of locomotor and urinary bladder ***,the Schwann cell survival and axonal regrowth persisted up to 6 months after the injury,even when treatment was delayed for 3 months to mimic chronic spinal cord *** findings collectively show promising evidence for a combinatorial strategy with chondroitinase ABC and Schwann cells in promoting remodeling and recovery of function following spinal cord injury.

关键词： axonal regrowth bladder function chondroitinase ABC functional recovery glial scar lentivirus migration Schwann cell spinal cord injury transplantation