检索结果-南通市图书馆

Mechanism of imipenem-induced mental disorder: A meta-analysis

World Journal of Psychiatry 2024年第10期14卷 1583-1591页

作者： Zhou-Hong Zhan Jia-Liang Wang Li-Hong Wang nan-nan Shen Xin-Wen Liu yan-na yu Fu-Rong Liu Department of Clinical Pharmacy Affiliated Hospital of Shaoxing UniversityShaoxing 312000Zhejiang ProvinceChina

BACKGROUND Imipenem is a highly effective carbapenem antibiotic,which is widely used in the treatment of many serious bacterial *** the same time,it can also cause some adverse reactions,mental abnormalities are the most concerned central nervous system adverse *** patients respond differently to imipenem,and the effect of imipenem on psychiatric disorders is ***,meta-analysis summarizing the results of multiple previous studies can provide stronger evidence support for clinical guidelines to guide clinical rational use of imipenem to minimize *** reviewing the literature published between 2003 and 2017,seven controlled trials with a total of 550 patients were included,with 273 and 277 patients in the control and experimental groups,*** sample size of the study ranged from a minimum of 30 cases to a maximum of 61 *** in the experimental group were treated with imipenem while the control group was treated with conventional ***-analysis showed that the incidence of mental disorders in the experimental group was higher than that in the control group(odds ratio=3.66,95%confidence interval:1.11-12.11,P=0.030);however,there was no significant difference in the incidence of adverse reactions between the two groups(odds ratio=0.05,95%confidence interval:0.00 to 0.10,P=0.060).Funnel diagrams showed that the scattered points of each study were symmetrical and distributed in an inverted funnel shape;therefore,there was no publication *** Imipenem can cause mental disorders in ***,the low quality of the included literature may have affected the final ***,it is necessary to conduct a high-quality randomized controlled study with multiple samples to further confirm the mechanism of imipenem-induced mental disorders and provide effective guidance for clinical treatment.

关键词： Imipenem Psychosis Drug mechanism Meta analysis Document resource quality

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

以危险因素评估为指导的预见性护理对上消化道出血患者止血时间、并发症及出血次数的影响

引用

医学信息 2024年第4期37卷 160-163页

作者：那艳宇天津市第二人民医院ICU

目的研究在上消化道出血患者护理中应用以危险因素评估为指导的预见性护理，对止血时间、并发症及出血次数的影响。方法选取2020年3月-2021年3月在我院诊治的74例上消化道出血患者为研究对象，采用随机数字表法分为对照组和观察组，... 详细信息

目的研究在上消化道出血患者护理中应用以危险因素评估为指导的预见性护理，对止血时间、并发症及出血次数的影响。方法选取2020年3月-2021年3月在我院诊治的74例上消化道出血患者为研究对象，采用随机数字表法分为对照组和观察组，各37例。对照组采用常规护理，观察组在对照组基础上给予以危险因素评估为指导的预见性护理干预，比较两组止血时间、出血次数、住院时间、并发症发生率、应激指标、生活质量水平以及护理满意度。结果观察组止血时间、出血次数、住院时间均小于对照组（P<0.05）；观察组并发症发生率为5.41%，低于对照组的16.22%(P<0.05)；两组护理后肾上腺素、去甲肾上腺素、血浆皮质醇水平均低于护理前，且观察组低于对照组（P<0.05）；两组护理后生活质量评分均高于护理前，且观察组大于对照组（P<0.05）；观察组护理满意度为94.59%，高于对照组的86.49%(P<0.05)。结论以危险因素评估为指导的预见性护理干预应用于上消化道出血患者中，可缩短止血时间，减少出血次数，降低并发症发生率，提高护理满意度，减小应激反应，促进患者生活质量水平的改善，具有确切的应用护理效果。

关键词：危险评估预见性护理上消化道出血

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

UiO-66-NH_(2)nanoparticles supported on layered double hydroxides as an excellent adsorbent for levofloxacin capture

引用

Particuology 2024年第9期92卷 155-165页

作者： yan Li Heng Lin Qiaolan yu na Ma Wei Dai College of Geography and Environmental Sciences Zhejiang Normal UniversityJinhua321004China Key Laboratory of the Ministry of Education for Advanced Catalysis Materials College of Chemistry and Materials ScienceZhejiang Normal UniversityJinhua321004China

The adsorption performances of individual adsorbent such as UiO-66-NH_(2)and MgAl-layered double hydroxides(MgAl-LDH)toward levofloxacin(LVX)is less satisfactory due to the disappointing uptake capacity and adsorption ***,a 3D flower-like composite adsorbent prepared via iterative hydrothermal synthesis method anchoring UiO-66-NH_(2)nanoparticles onto the MgAl-LDH *** to the synergistic effects of UiO-66-NH_(2),and MgAl-LDH,the MgAl-LDH@UiO-66-NH_(2)exhibits an outstanding adsorption performance toward ***,the maximum LVX uptake capacity over MgAl-LDH@UiO-66-NH_(2)reached 268 mg/g,which was higher than that of the individual adsorption materials UiO-66-NH_(2)(41 mg/g),MgAl-LDH(140 mg/g),and some adsorbents reported in previous *** rapid adsorption process can reach equilibrium within 20 min,which conformed well to the pseudo-second-order kinetics and the Langmuir isotherm *** thermodynamic result also indicated that the adsorption was spontaneous and exothermic,simultaneous coexisting physical and chemical adsorption ***,the MgAl-LDH@UiO-66-NH_(2)still maintained excellent adsorption capacity with a slightly decrease after fifth cycle,exhibiting a remarkable reuse and stable *** work provides a highly novel strategy to prepare recyclable composite adsorbent for the LVX capture from aqueous solution.

关键词： Layered double hydroxides UiO-66-NH_(2) LVX Adsorption

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ginsenoside Rd Induces Differentiation of Myeloid Leukemia Cells via Regulating ERK/GSK-3βSignaling Pathway

引用

Chinese Journal of Integrative Medicine 2024年第7期30卷 588-599页

作者： JIANG yu-xia ZHAO yan-na yu Xiao-ling YIN Li-ming Department of Hematology Tongde Hospital of Zhejiang ProvinceHangzhou310012China Institute of Hematology Research the First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine)Hangzhou310006China

Objective To investigate the role of ginsenoside Rd(GRd)in acute myeloid leukemia(AML)cell *** AML cells were treated with GRd(25,50,100 and 200µg/mL),retinoic acid(RA,0.1g/L)and PD98059(20 mg/mL)for 72 h,cell survival was detected by methylthiazolyldiphenyl-tetrazolium bromide and colony formation assays,and cell cycle was detected by flow *** morphology and differentiation were observed by Wright-Giemsa staining,peroxidase chemical staining and cellular immunochemistry assay,*** protein expression levels of GATA binding protein 1(GATA-1),purine rich Box-1(PU.1),phosphorylated-extracellular signal-related kinase(p-ERK),ERK,phosphorylated-glycogen synthase kinase-3β(p-GSK3β),GSK3βand signal transducer and activator of transcription 1(STAT1)were detected by Western ***-six mice were randomly divided into 3 groups using a random number table:model control group(non-treated),GRd group[treated with 200 mg/(kg·d)GRd]and homoharringtonine(HTT)group[treated with 1 mg/(kg·d)HTT].A tumor-bearing nude mouse model was established,and tumor weight and volume were *** of subcutaneous tumor tissue were observed after hematoxylin and eosin ***1 and GATA-1 expressions were detected by immunohistochemical *** The cell survival was inhibited by GRd in a dose-dependent manner and GRd caused G0/G1 cell arrest(p<0.05).GRd treatment induced leukemia cell differentiation,showing increased expressions of peroxidase and specific proteins concerning erythrogenic or granulocytic differentiation(p<0.05).GRd treatment elicited upregulation of p-ERK,p-GSK-3βand STAT1 expressions in cells,and reversed the effects of PD98059 on inhibiting the expressions of peroxidase,GATA-1 and PU.1(P<0.05).After GRd treatment,tumor weight and volume of mice were decreased,and tumor cells underwent massive apoptosis and necrosis(P<0.05).WT1 level was decreased,and GATA-1 level was significantly increased in subcutaneous tumor ti

关键词： ginsenoside Rd myeloid leukemia survival differentiation extracellular signal-related kinase signaling pathway

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Partial Linear Model Averaging Prediction for Longitudinal Data

引用

Journal of Systems Science & Complexity 2024年第2期37卷 863-885页

作者： LI na FEI yu ZHANG Xinyu Faculty of Science Kunming University of Science and TechnologyKunming 650500China School of Statistics and Mathematics Yunnan University of Finance and EconomicsKunming 650221China Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100190China

Prediction plays an important role in data *** averaging method generally provides better prediction than using any of its *** though model averaging has been extensively investigated under independent errors,few authors have considered model averaging for semiparametric models with correlated *** this paper,the authors offer an optimal model averaging method to improve the prediction in partially linear model for longitudinal *** model averaging weights are obtained by minimizing criterion,which is an unbiased estimator of the expected in-sample squared error loss plus a *** properties,including asymptotic optimality and consistency of averaging weights,are established under two scenarios:(i)All candidate models are misspecified;(ii)Correct models are available in the candidate *** studies and an empirical example show that the promise of the proposed procedure over other competitive methods.

关键词： Asymptotic optimality longitudinal data model averaging estimator partially linear model prediction

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dynamic Response Impact of Vehicle Braking on Simply Supported Beam Bridges with Corrugated Steel Webs Based on Vehicle-Bridge Coupled Vibration Analysis

引用

Computer Modeling in Engineering & Sciences 2024年第6期139卷 3467-3493页

作者： yan Wang Siwen Li na Wei School of Civil Engineering Zhengzhou UniversityZhengzhou450001China

A novel approach for analyzing coupled vibrations between vehicles and bridges is presented,taking into account spatiotemporal effects and mechanical phenomena resulting fromvehicle *** modeling and solution of bridge vibrations induced by vehicle deceleration are realized using this *** method’s validity and reliability are substantiated through numerical examples.A simply supported beam bridge with a corrugated steel web is taken as an example and the effects of parameters such as the initial vehicle speed,braking acceleration,braking location,and road surface roughness on the mid-span displacement and impact factor of the bridge are *** results show that vehicle braking significantly amplifies mid-span displacement and impact factor responses in comparison to uniform vehicular motion across the ***,the influence of wheelto-bridge friction forces is of particular significance and cannot be *** the vehicle initiates braking near the middle of the span,both the mid-span displacement and impact factor of the bridge exhibit substantial increases,further escalating with higher braking *** favorable road surface conditions,the midspan displacement and the impact factor during vehicle braking may exceed the design values stipulated by *** is important to note that road surface roughness exerts a more pronounced effect on the impact factor of the bridge in comparison to the effects of vehicle braking.

关键词： Corrugated steel web girder bridges simply supported beam bridges vehicle-bridge coupled vibration braking impact factor

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A New Encrypted Traffic Identification Model Based on VAE-LSTM-DRN

引用

Computers, Materials & Continua 2024年第1期78卷 569-588页

作者： Haizhen Wang Jinying yan na Jia College of Computer and Control Engineering Qiqihar UniversityQiqihar161006China Heilongjiang Key Laboratory of Big Data Network Security Detection and Analysis Qiqihar UniversityQiqiharChina

Encrypted traffic identification pertains to the precise acquisition and categorization of data from traffic datasets containing imbalanced and obscured *** extraction of encrypted traffic attributes and their subsequent identification presents a formidable *** existing models have predominantly relied on direct extraction of encrypted traffic data from imbalanced datasets,with the dataset’s imbalance significantly affecting the model’s *** the present study,a new model,referred to as UD-VLD(Unbalanced Dataset-VAE-LSTM-DRN),was proposed to address above *** proposed model is an encrypted traffic identification model for handling unbalanced *** encoder of the variational autoencoder(VAE)is combined with the decoder and Long-short term Memory(LSTM)in UD-VLD model to realize the data enhancement processing of the original unbalanced *** enhanced data is processed by transforming the deep residual network(DRN)to address neural network gradient-related ***,the data is classified and *** UD-VLD model integrates the related techniques of deep learning into the encrypted traffic recognition technique,thereby solving the processing problem for unbalanced *** UD-VLD model was tested using the publicly available Tor dataset and VPN *** UD-VLD model is evaluated against other comparative models in terms of accuracy,loss rate,precision,recall,F1-score,total time,and ROC *** results reveal that the UD-VLD model exhibits better performance in both binary and multi classification,being higher than other encrypted traffic recognition models that exist for unbalanced ***,the evaluation performance indicates that the UD-VLD model effectivelymitigates the impact of unbalanced data on traffic *** can serve as a novel solution for encrypted traffic identification.

关键词： Data enhancement LSTM deep residual network VAE

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Land use change and its driving factors in the ecological function area:A case study in the Hedong Region of the Gansu Province,China

引用

Journal of Arid Land 2024年第1期16卷 71-90页

作者： WEI Zhudeng DU na yu Wenzheng School of Geographical Science Nanjing University of Information Science&TechnologyNanjing 210044China

Land use and cover change(LUCC)is important for the provision of ecosystem *** increasing number of recent studies link LUCC processes to ecosystem services and human well-being at different scales ***,the dynamic of land use and its drivers receive insufficient attention within ecological function areas,particularly in quantifying the dynamic roles of climate change and human activities on land use based on a long time *** study utilizes geospatial analysis and geographical detectors to examine the temporal dynamics of land use patterns and their underlying drivers in the Hedong Region of the Gansu Province from 1990 to *** indicated that grassland,cropland,and forestland collectively accounted for approximately 99% of the total land *** initially increased and then decreased after 2000,while grassland decreased with *** contrast,forestland and construction land were continuously expanded,with net growth areas of 6235.2 and 455.9 km^(2),*** 1990 to 2020,cropland was converted to grassland,and both of them were converted to forestland as a *** expansion of construction land primarily originated from *** 2000 to 2005,land use experienced intensified temporal dynamics and a shift of relatively active zones from the central to the southeastern *** yield,economic factors,and precipitation were the major factors accounting for most land use *** impacts on land use changes were stronger before 1995,succeeded by the impact of animal husbandry during 1995-2000,followed by the impacts of grain production and gross domestic product(GDP)after ***,agricultural and pastoral activities,coupled with climate change,exhibited stronger enhancement effects after 2000 through their interaction with population and economic *** patterns closely correlated with ecological restoration projects in China since *** study implies the importance of synergy be

关键词： land use land type geographic detector driving mechanism Hedong Region

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Comparative analysis of the microbiome of sympatric wintering Bean Geese,Domestic Ducks,humans,and soil at Shengjin Lake of China reveals potential public risk to human health

引用

Avian Research 2024年第2期15卷 279-286页

作者： Gang Liu na Xu Chongyang yu College of Life Sciences Anhui Medical UniversityHefei 230032China

The gut microbiota of migratory waterbirds is affected by various complex factors,including cross-species transmission,which increases the risk of pathogen spreading among sympatric animals and poses a potential public health risk to *** this study,we investigated the microbial communities of wintering Bean Geese(Anser fabalis),Domestic Ducks(*** domesticus),humans,and soil using high-throughput sequencing of the 16S rRna gene region in Shengjin Lake,*** total,6,046,677 clean reads were obtained,representing 41,119 operational taxonomic units(OTUs)across the four *** dominant microbial phyla were the Proteobacteria,Firmicutes,Bacteroidota,and *** Sorensen similarity index and alpha and beta diversity results showed that the gut microbial communities of Bean Geese and Domestic Ducks were more similar to those of the other *** analysis revealed that Faecalibacterium prausnitzii,Pseudomonas fragi,and Bradyrhizobium elkanii were hubs of the three major *** common microbiomes were iden-tified in Bean Geese,Domestic Ducks,humans,and soil in Shengjin Lake.A total of 96 potential pathogens were identified among the four groups,with 20 specific potentially pathogenic microbiomes found in the gut of Bean *** of these pathogens are responsible for significant financial losses in the poultry industry and pose risks to human *** pneumoniae,Morganella morganii,Escherichia coli,and Ralstonia insidiosa are potential core pathogens found in the four groups at Shengjin Lake that can cause diseases in humans and an-imals and facilitate cross-species transmission through various ***,humans are at risk of con-tracting these pathogens from migratory birds because of their frequent contact with domestic ***,further studies are required to explore the potential pathogenic species and transmission pathways among sympatric wintering Bean Geese,Domestic Ducks,humans,and soil.

关键词： Microbiome Migratory waterbird Pathogens Poultry Sympatric species

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Equivalent linear model for seismic damage evaluation of single-degree-of-freedom systems representing reinforced concrete structures considering cyclic degradation behavior

引用

Earthquake Engineering and Engineering Vibration 2024年第3期23卷 637-648页

作者： Lulu yan Ding-Hao yu Research Center for Geotechnical and Structural Engineering Technology of Liaoning Province Dalian UniversityDalian116622China State Key Laboratory of Coastal and Offshore Engineering Dalian University of TechnologyDalian 116024China

In this study,a novel equivalent damping ratio model that is suitable for reinforced concrete(RC)structures considering cyclic degradation behavior is developed,and a new equivalent linearization analysis method for implementing the proposed equivalent damping ratio model for use in seismic damage evaluation is *** this end,Ibarra’s peak-oriented model,which incorporates an energy-based degradation rule,is selected for representing hysteretic behavior of RC structure,and the optimized equivalent damping for predicting the maximum displacement response is presented by using the empirical method,in which the effect of cyclic degradation is ***,the relationship between the hysteretic energy dissipation of the inelastic system and the elastic strain energy of the equivalent linear system is established so that the proposed equivalent linear system can be directly integrated with the Park-Ang seismic model to implement seismic damage *** to the simplicity of the equivalent linearization method,the proposed method provides an efficient and reliable way of obtaining comprehensive insight into the seismic performance of RC *** verification demonstrates the validity of the proposed method.

关键词： degrading system equivalent linear system equivalent damping seismic damage RC structures

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：