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Atomic study of hydrogen behaviors at∑3(111)grain boundary in equiatomic CoCrNi and CoCrNiFe alloys

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Tungsten 2022年第3期4卷 239-247页

作者： Hua-Qing Guan yan-mei jing Shao-Song Huang Key Laboratory of Material Modification by Laser Ion and Electron Beams(Dalian University of Technology)Ministry of EducationDalian116024China

High-entropy alloys are potential advanced structural materials for applications in nuclear energy due to their proved high irradiation ***,exposing components made of structure materials to service conditions under certain nuclear environments may induce hydrogen embrittlement(HE)as one of the typical failure *** this work,we performed density functional theory(DFT)calculations to examine the role of specific element species in HE mechanism in CoCrNi and CoCrNiFe *** solution energy,binding energy and diffusion barrier of H atoms at∑3 GBs(GBs is short for grain boundaries)are *** on the DFT data,we found that Cr limits the H atom to a specific potential position,thus suppresses H *** dipole moment interaction between H and Fe atoms weakens the binding of H *** lattice distortion effect-induced trapping for H provides higher H diffusion barriers at∑3 GBs than that in pure Ni.

关键词： Hydrogen embrittlement Grain boundary DFT High-entropy alloy

IRF1 enhances the expression of human DNA polymerase η in response to carcinogen N-methyl-N'-nitro-N-nitrosoguanidine

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中国病理生理杂志 2010年第A10期26卷 2004-2005页

作者： ZHU Hui-fang,FAN yan-feng,QI Hong-yan,SHEN jing,mei Ru-huan,SHAO Ji-min(Department of Pathology and Pathophysiology,Zhejiang University School of Medicine,Hangzhou 310058,China)

Human DNA polymerase η,a low-fidelity DNA polymerase,plays an important role in genesis of non-targeted mutations in cells in response to the mutagen and carcinogen N-methyl-N’-nitro-N-nitrosoguanidine(MNNG).In this study,we showed that the expression of Pol η was up-regulated in human amnion FL cells stimulated by MNNG,and the putative promoter of POLH gene was activated in response to MNNG *** gene assays with deletion constructs of the POLH promoter

关键词： nitro DNA targeted promoter deletion fidelity genesis putative constructs instability

“一带一路”沿线国家FDI空间布局与污染转移的实证研究

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软科学 2017年第3期31卷 25-29页

作者：苏红岩李京梅中国海洋大学经济学院山东青岛266100

基于2000~2013年省际数据,运用静态和动态面板模型分析"一带一路"沿线国家FDI空间布局与我国主要工业污染物分布转移的关系,进一步研究影响沿线FDI布局转移的因素,得出结论:我国主要工业污染物分布转移与沿线国家FDI空间布局正相关;环... 详细信息

基于2000~2013年省际数据,运用静态和动态面板模型分析"一带一路"沿线国家FDI空间布局与我国主要工业污染物分布转移的关系,进一步研究影响沿线FDI布局转移的因素,得出结论:我国主要工业污染物分布转移与沿线国家FDI空间布局正相关;环境规制强度、制造业中污染密集型行业集聚程度、劳动力工资水平等对沿线国家FDI空间布局影响显著;沿线国家FDI在我国的地区布局具有显著自我累积效应。从合理环境规制的制定实施、区域差异化利用外资等方面提出提高外资利用效率的建议。

关键词：一带一路污染转移静态动态面板分析

“大系”里的“小文章”——读《1917-1927中国新文学大系导言集》

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成都师范学院学报 2013年第11期29卷 76-79页

作者：闫美景安徽大学文学院合肥230039

《1917-1927中国新文学大系导言集》为我们再现了五四新文化运动主帅和干将们的阵容。他们笔端流露的是对自己曾经开风气之先的那场奋斗的自信,也是站在20年后的立场斟酌取舍的叙说。蔡元培忽视了周作人,茅盾略过了胡适,胡适批评了陈独... 详细信息

《1917-1927中国新文学大系导言集》为我们再现了五四新文化运动主帅和干将们的阵容。他们笔端流露的是对自己曾经开风气之先的那场奋斗的自信,也是站在20年后的立场斟酌取舍的叙说。蔡元培忽视了周作人,茅盾略过了胡适,胡适批评了陈独秀,郁达夫被"贬谪"……20年后的这次五四新文化干将们的集体回视,是一次此我与彼我的对话,叙说的姿态没有谁是谁非,其中有坚持自我,有彼此分裂。我们庆幸的唯是从他们叙说的姿态中窥见一斑历史的遗迹。

关键词：新文学大系文学革命五四新文化运动

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孤独的姿态——管窥张爱玲“流言体”散文

郧阳师范高等专科学校学报 2014年第1期34卷 40-43页

作者：闫美景安徽大学文学院安徽合肥230039

张爱玲的散文独具魅力,被誉为"流言体"。在20世纪40年代低气压时期的上海,张爱玲的散文以其耽溺于个人情感的展现和世俗小市民的纵情描绘,不追逐时代共振声音的洪流,而成为一种异质话语。她对世俗生活的审视有着孤独者的姿态,世俗的声... 详细信息

张爱玲的散文独具魅力,被誉为"流言体"。在20世纪40年代低气压时期的上海,张爱玲的散文以其耽溺于个人情感的展现和世俗小市民的纵情描绘,不追逐时代共振声音的洪流,而成为一种异质话语。她对世俗生活的审视有着孤独者的姿态,世俗的声音是这孤独姿态的面具,蕴含着家国情结和曲高和寡的苍凉。她散文的艺术魅力影响后世,两岸三地均有传人。

关键词：张爱玲 “流言体”散文孤独艺术特色

Treatment of gastric varices by endoscopic sclerotherapy using butyl cyanoacrylate:10 years' experience of 635 cases

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Chinese Medical Journal 2007年第23期120卷 2081-2085页

作者： CHENG Liu-fang WANG Zhi-qiang LI Chang-zheng CAI Feng-chun HUANG Qi-yang LINGHU En-qiang LI Wen CHAI Guo-jun SUN Guo-hui MAO Yong-ping WANG yan-mei LI jing GAO Ping FAN Tie-yan Department of Gastroenterology and Hepatology General Hospital of Chinese People＇s Liberation Army Beijing 100853 China

Background Gastric varices （GV） are life-threatening for patients with portal hypertension. Endoscopic injection with butyl cyanoacrylate （BC）, the mainstay of the therapy for GV, has been reported to be effective for hemostasis of bleeding varices, but its efficacy in the obliteration of GV and impact on the survival of patients still needs clarification. Here we summarized our experience of 10 years＇ practice to evaluate the efficacy and safety of endoscopic therapy using BC for GV patients. Methods From January 1997 to April 2006, GV cases treated with endoscopic injection using BC were collected. The ＂sandwich method＂ and the ＂modified sandwich method＂ were used to inject BC intravascularly. Retrograde analysis was made on the data of treatment and follow-up. Results A total of 635 GV cases treated with endoscopic injection using BC were collected, most of them （90.2%） suffered from post-hepatitis cirrhosis. Emergency hemostasis was achieved in 139 out of 146 sessions （95.2%）. Complications occurred in 32 cases （5.2%）, including hemorrhage due to early expulsion of tissue glue （3.1%）, septicemia （1%） and ectopic thrombosis （0.5%）, such as spleen infarction. Endoscopic follow-up in 503 patients showed complete disappearance （76.9%）, collapse （17.3%） or remnants （5.8%） of gastric varices. A total of 550 patients were followed up clinically for 3 to 115 months. Of these patients, 44 had recurrent bleeding （8.0%） and 44 died from hepatic failure, recurrent bleeding, hepatic carcinoma or other causes. The longest survival was 115 months, with a median survival of 25 months. Survival rates at 1,2, 3, 4 and 5 year were 95%, 92%, 90%, 83% and 81%, respectively. Conclusions Endoscopic sclerotherapy with BC is effective for the hemostasis of bleeding GV, as well as obliteration of GV which contributes to less rebleeding and better survival. The modified sandwich method may be useful to minimize ectopic embolism, which we speculated to result from excess iodized oil.

关键词： gastric varices endoscopic sclerotherapy butyl cyanoacrylate survival

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应急输送铁路车辆快速集结算法研究

天津纺织工学院学报 2000年第2期19卷 50-52页

作者：阎京梅余贻荣天津纺织工学院计算机技术与自动化系天津300160 解放军军事交通学院天津300161

针对改进后的应急铁路输送方法进行计算机模拟 ,主要解决原始铁路车辆信息数据库的结构设计以及在此基础上进行指定范围、指定装载站的铁路车辆集结时间的预测算法问题 .预测算法实现后 ,结果与实际情况吻合良好 ,为应急铁路输送的自动... 详细信息

针对改进后的应急铁路输送方法进行计算机模拟 ,主要解决原始铁路车辆信息数据库的结构设计以及在此基础上进行指定范围、指定装载站的铁路车辆集结时间的预测算法问题 .预测算法实现后 ,结果与实际情况吻合良好 ,为应急铁路输送的自动化确立了算法基础 .

关键词：装载站车辆集结应争铁路输送计算机模拟

Brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior

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Neural Regeneration Research 2025年第1期20卷 159-173页

作者： Man Han Deyang Zeng Wei Tan Xingxing Chen Shuyuan Bai Qiong Wu Yushan Chen Zhen Wei Yufei mei yan Zeng Brain Science and Advanced Technology Institute Wuhan University of Science and TechnologyWuhanHubei ProvinceChina Geriatric Hospital Affiliated to Wuhan University of Science and Technology WuhanHubei ProvinceChina School of Public Health Wuhan University of Science and TechnologyWuhanHubei ProvinceChina

Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral *** studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific,particularly involving the corticolimbic system,including the ventral tegmental area,nucleus accumbens,prefrontal cortex,amygdala,and *** how brain-derived neurotrophic factor participates in stress processing in different brain regions will deepen our understanding of social stress *** this review,we discuss the expression and regulation of brain-derived neurotrophic factor in stress-sensitive brain regions closely related to the pathophysiology of *** focused on associated molecular pathways and neural circuits,with special attention to the brain-derived neurotrophic factor–tropomyosin receptor kinase B signaling pathway and the ventral tegmental area–nucleus accumbens dopamine *** determined that stress-induced alterations in brain-derived neurotrophic factor levels are likely related to the nature,severity,and duration of stress,especially in the above-mentioned brain regions of the corticolimbic ***,BDNF might be a biological indicator regulating stress-related processes in various brain regions.

关键词： amygdala chronic mild stress chronic social defeat stress corticolimbic system depression hippocampus medial prefrontal cortex nucleus accumbens social stress models ventral tegmental area

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广州市临终关怀机构资源及现状调查

中国公共卫生 2018年第3期34卷 412-414页

作者：郝燕萍李艳媚庄静仪张尧广州医科大学护理学院外科护理教研室广州医科大学护理学院

目的了解广东省广州市临终关怀机构的资源及现状,为优化人力资源配备、促进临终关怀事业发展提供参考。方法于2016年9—11月对广州市13家开展临终关怀服务的卫生机构以现场发放问卷的形式了解人力和设备资源现状。结果 13家医疗机构床... 详细信息

目的了解广东省广州市临终关怀机构的资源及现状,为优化人力资源配备、促进临终关怀事业发展提供参考。方法于2016年9—11月对广州市13家开展临终关怀服务的卫生机构以现场发放问卷的形式了解人力和设备资源现状。结果 13家医疗机构床位数共2 437张,其中临终病床672张,约占总床位的27.6%;医护人员1 259人,执业医生492人,注册护士767人,护工522人;护士/床位为0.3:1;仅有4家机构的护士每人每年培训时间>30 h;近一年住院病人数约14 808人,其中临终病人数2 662人,占住院病人数的18%;临终病人平均住院日为15~89 d,死因前3位分别是心血管疾病、脑血管疾病及晚期恶性肿瘤;有2家机构对家属探视时间不设限。结论广州市临终病床数量严重匮乏,机构资源配置不足,临终关怀服务覆盖率低;机构建设不完善,团队建设亟待加强,缺乏规范化的服务及业务培训,整体服务水平不高;实际运行中存在诸多困难;临终关怀机构需为家属陪护与探视提供更多便利。

关键词：临终关怀资源分配服务现状