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Numerical Modelling for Dynamic Instability Process of Submarine Soft Clay Slopes Under Seismic Loading

Journal of Ocean University of China 2021年第5期20卷 1109-1120页

作者： MI yang WANG Jianhua CHENG Xinglei yan xiaowei State Key Laboratory of Hydraulic Engineering Simulation and Safety Tianjin UniversityTianjin 300072China Geotechnical Engineering Institute Tianjin UniversityTianjin 300072China

Marine geological disasters occurred frequently in the deep-water slope area of the northern South China Sea,especially submarine landslides,which caused serious damage to marine *** cyclic elastoplastic model that can describe the cyclic stress-strain response characteristic for soft clay,is embedded into the coupled Eulerian-Lagrangian(CEL)algorithm of ABAQUS by means of subroutine interface *** the basis of CEL technique and undrained cyclic elastoplastic model,a method for analyzing the dynamic instability process of marine slopes under the action of earthquake load is *** rationality for cyclic elastoplastic constitutive model is validated by comparing its calculated results with those of von Mises model built in *** dynamic instability process of slopes under different conditions are *** results indicate that the deformation accumulation of soft clay have a significant effect on the dynamic instability process of submarine slopes under earthquake *** cumulative deformation is taken into our model and this makes the calculated final deformation of the slope under earthquake load larger than the results of conventional numerical *** different contact conditions are used for analysis,the smaller the friction coefficient is,the larger the deformation of slopes will be.A numerical analysis method that can both reflect the dynamic properties of soft clay and display the dynamic instability process of submarine landslide is proposed,which could visually predict the topographies of the previous and post failure for submarine slope.

关键词： submarine slope saturated soft clay coupled Eulerian-Lagrangian cyclic elastoplastic model dynamic instability process

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Current knowledge of Krüppel-like factor 5 and vascular remodeling: providing insights for therapeutic strategies

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Journal of Molecular Cell Biology 2021年第2期13卷 79-90页

作者： Ziyan Xie Junye Chen Chenyu Wang Jiahao Zhang yanxiang Wu xiaowei yan Department of Cardiology Peking Union Medical College HospitalPeking Union Medical College&Chinese Academy of Medical SciencesBeijing 100730China Department of Vascular Surgery Peking Union Medical College HospitalPeking Union Medical College&Chinese Academy of Medical SciencesBeijing 100730China

Vascular remodeling is a pathological basis of various disorders. Therefore, it is necessary to understand the occurrence, prevention, and treatment of vascular remodeling. Krüppel-like factor 5 (KLF5) has been identified as a significant factor in cardiovascular diseases during the last two decades. This review provides a mechanism network of function and regulation of KLF5 in vascular remodeling based on newly published data and gives a summary of its potential therapeutic applications. KLF5 modulates numerous biological processes, which play essential parts in the development of vascular remodeling, such as cell proliferation, phenotype switch, extracellular matrix deposition, inflammation, and angiogenesis by altering downstream genes and signaling pathways. Considering its essential functions, KLF5 could be developed as a potent therapeutic target in vascular disorders.

关键词： Krüppel-like factor 5(KLF5) vascular remodeling inflammation angiogenesis drug development microRNA

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Histone chaperone Spt16p is required for heterochromatin mediated silencing in budding yeast

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Protein & Cell 2018年第7期9卷 652-658页

作者： yan, xiaowei yang, Jiayi Xu, Jiawei Feng, Jianxun Li, Qing State Key Laboratory of Protein and Plant Gene Research School of Life Sciences and Peking-Tsinghua Center for Life Sciences Peking University Beijing China Department of Cellular and Molecular Pharmacology Howard Hughes Medical Institute University of California San Francisco San Francisco CA USA State Key Laboratory of Protein and Plant Gene Research School of Life Sciences and Peking-Tsinghua Center for Life Sciences Peking University Beijing China

Dear Editor,Heterochromatin, the highly-condensed nucleosome arrays in chromosomes, plays an important role in regulating mul- tiple cellular events including transcriptional silencing and chromosome segregation （Allis and Jenuwein, 2016）. Aberrant heterochromatin formation is linked to tumor pro- gression, as well as other severe physiological disorders （Hahn et al., 2010）. However, the mechanism by which factors contribute to heterochromatin formation remains elusive.

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A Simple and Efficient Copper（Ⅱ） Complex as a Catalyst for N-Arylation of Imidazoles

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Chinese Journal of Chemistry 2013年第2期31卷 267-270页

作者： yanli Jiao Nannan yan Jianwei Xie xiaowei Ma Ping Liu Bin Dai School of Chemistry and Chemical Engineering the Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan Shihezi University North 4th Road Shihezi Xinjiang 832003 China

Four inexpensive and air-/moisture-stable pyrrolecarbaldiminato-Cu complexes 1-4 were synthesized and evaluated to be a novel class of catalysts for the N-arylation of imidazoles with aryl halides. A variety of aryl iodides, bromides and activated aryl chlorides underwent the coupling with imidazoles, promoted by the catalyst 4, in moderate to good yields without the protection by an inert gas.

关键词： pyrrolecarbaldiminato-Cu complexes homogeneous catalyst N-arylation imidazoles N-heterocycles

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Measurement of the echo reduction for underwater acoustic passive materials by using the time reversal technique

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Chinese Journal of Acoustics 2016年第3期35卷 309-320页

作者： yan xiaowei LI Jianlong HE Zhiguang Institute of System Engineering Research College of Information Science & Electronic Engineering Zhejiang University

A measuring method of the echo reduction of passive materials by using the time reversal（TR） technique is presented. To measure the echo reduction of a sample with this approach, the received signals are firstly focused according to the TR theory. Then, the sample is removed and the TR processing is again employed to realize the focus of the received ***, the echo reduction of the sample is evaluated with these focusing signals. Besides, to calibrate the measured echo reduction via the TR technique, a standard sample is employed to measure a constant coefficient that only depends on the measurement environment. An aluminum plate sample and a steel plate sample with the same size of 1.1 mxl.O m x0.005 m axe tested in a wave guide tank. The experimental results show that the calibrated values are well consistent with theoretical results under the free field at the measured frequency range of0.5-20 kHz. The relative errors of all the measured values are less than 10% and the values of the expanded uncertainty are less than 1.5 dB. The TR processing focuses the energy in spatial domain and temporal domain, so it can be used to measure the echo reduction of passive materials in the environments with reflections induced by boundaries and low frequency sources.

关键词： time Measurement of the echo reduction for underwater acoustic passive materials by using the time reversal technique TR

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Measurement of insertion loss for underwater acoustic passive materials with the time reversal technique

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Chinese Journal of Acoustics 2014年第2期33卷 109-120页

作者： yan xiaowei LI Jianlong KONG Xiangdong Institute of System Engineering Research Department of Information Science&Electronic Engineering Zhejiang University

A method using the time reversal（TR） technique to measure the insertion loss（IL） of passive materials is *** the received signals are focused according to the TR theory when there is not a sample between the source and the received ***,the sample is placed near the received array and the TR processing is again employed to realize the focus of the received ***,the IL of the sample is evaluated from these focusing *** the TR processing can focus the energy in spatial domain and time domain,the method can be used to measure acoustic properties of passive materials in a waveguide tank with reflections induced by boundaries or with low source *** samples with the same size of 1.1 m×1.0 m×5 mm are tested in the waveguide *** method is demonstrated by the comparison of the theoretical and the experimental results in the measured frequency range of 1-20 kHz.

关键词： time Measurement of insertion loss for underwater acoustic passive materials with the time reversal technique TR

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Investigation on Psychological First Aid knowledge of Chinese university students and effects of relevant health education

Investigation on Psychological First Aid knowledge of Chines...

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中华医学会急诊医学分会第17次全国急诊医学学术年会

作者： xiaowei yan Jie Wei Renmin Hospital Of Wuhan University

Introduction to investigate the psychological first aid understanding of Chinese university students,their willingness to learn and implement,and evaluate the training effectiveness,to explore the essence and methods of psychological first aid training among university *** Self-made questionnaire was designed for 213 students who chose"Disaster Medicine"course in Wuhan University in 2013,before and after the relevant education,the

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未爆子弹药图像数据集构建方法及其关键技术研究

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航空兵器 2024年第4期31卷 21-32页

作者：闫小伟陈栋陆军炮兵防空兵学院高过载弹药制导控制与信息感知实验室合肥230031

随着计算机技术和机器视觉技术的迅速发展与应用,探索基于“人工智能+”模型的未爆子弹药搜寻技术受到了广泛关注。但是,由于未爆子弹药具有一定的危险性和受军事应用的特殊性影响,数据集构建是目前亟待解决的瓶颈问题。本文由此出发,... 详细信息

随着计算机技术和机器视觉技术的迅速发展与应用,探索基于“人工智能+”模型的未爆子弹药搜寻技术受到了广泛关注。但是,由于未爆子弹药具有一定的危险性和受军事应用的特殊性影响,数据集构建是目前亟待解决的瓶颈问题。本文由此出发,分别论述了真实实物图像数据集和利用实物图片进行三维重建数据集的构建方法及流程,重点分析了两种数据集构建过程中的相关关键技术及其优缺点,并给出了一种利用多目相机采集目标图像和地理坐标信息,然后利用深度学习算法进行目标特征提取、生成三维点云和融合三维图像。试验结果表明,采用该方法构建的三维数据集可以有效解决未爆子弹药现有数据集数据量不足的问题,最后展望了数据集构建方法的未来发展方向。

关键词：未爆子弹药图像数据集深度学习三维重建图像处理

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Sequence Mutation of Exon 7 of Badh2 Gene and Aroma Identification of Fragrant Rice Varieties

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Agricultural Biotechnology 2020年第5期9卷 5-8页

作者： Qingjie TANG Jianxiao CHEN Liqiong TANG Yisheng HAN xiaowei yan Cereal Crops Institute Hainan Academy of Agricultural Sciences/Key Laboratory of Crop Genetics and Breeding of Hainan ProvinceHaikou 571100China

In this study,we performed amplificaion and sequence analysis of exon7 of gene Badh2 of 12 fragrant rice materials,and identified the aroma of fragrant rice materials by the method of seed chewing and KOH soaking,so as to analyze the sequence mutation of exon 7 in the Badh2 gene of rice material and its corresponding relation with the flavor *** results showed that an 8 bp deletion(aaaa--t---ggc)and a mutation of SNP(g→t)in exon 7 of Badh2 gene were found in 10 materials,including Xiangnuo,Lvjinxiang,Meixiangzhan 2,Huaxiang,Yuexiangxuan 1,Hongyuxiang,Meixiangxuan 1,Baxiangxuan 1,Taixiangxuan 1,Taixiangxuan *** mutation was consistent with the mutation of EU155083 sequence in GenBank and was reported for the first time in Chinese rice *** these 10 fragrant rice materials with mutation,Huaxiang and Meixiangxuan 1 were identified as the heterozygote genotype,and Hongyuxiang was identified as non-fragrant rice,so the sequence mutation in exon 7 of Badh2 gene in fragrant rice materials did not correspond to aroma traits one by one;and 7 materials were identified as fragrant rice,and the brown rice of Meixiangzhan 2 and Yuexiangyuan 1 had sweet *** results could provide a reference for the research on the genetic mechanism of rice aroma character and the promotion of fragrant rice varieties.

关键词： Fragrant rice Badh2 Sequence mutation Aroma identification

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Evaluation and Identification of Resistance to Diseases and Pests for Rice Varieties in Hainan

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Agricultural Biotechnology 2020年第4期9卷 41-44页

作者： Qingjie TANG Xinjie CEN Liqiong TANG Jianxiao CHEN xiaowei yan Cereal Crops Institute Hainan Academy of Agricultural Sciences/Key Laboratory of Crop Genetics and Breeding of Hainan ProvinceHaikou 571100China

[Objectives]This study was conducted to select multi-resistant rice varieties in Hainan.[Methods]Seven new rice germplasms were identified by naturally induced disease nursery,field spraying and artificial inoculation.[Results]The restorer line Haihui 1558 was resistant to the dominant races ZB and ZC of rice blast and Tryporyza incertulas,and moderately resistant to pathotype IV of bacterial *** restorer line Haihui 227 was resistant to pathotype IV of bacterial blight and *** rice Hainonghong 1 was resistant to pathotype IV of bacterial blight,and moderately resistant to the dominant races ZB and ZC of rice *** glutinous rice Haifengheinuo 2 was moderately resistant to pathotypes IV of bacterial blight and ***.[Conclusions]The study provides reference for utilization of rice breeding on resistance to diseases and pests.

关键词： Rice landrace Rice blast Bacterial blight Tryporyza incertulas Brown planthopper Identification

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