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Efficacy and safety of Yiqi Peiyuan granules for improving the short-term prognosis of patients with acute kidney injury:A multicenter,double-blind,placebo-controlled,randomized trial

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Journal of Integrative Medicine 2024年第3期22卷 279-285页

作者： Jia-jia Wu Tian-yi Zhang Ying-hui Qi Min-yan {2. yan Fang Chao-jun Qi Li-ou Cao Ji-fang Lu Bo-han Lu Lu-min Tang jian-xiao shen Shan Mou Department of Nephrology Molecular Cell Lab for Kidney DiseaseShanghai Peritoneal Dialysis Research CenterUremia Diagnosis and Treatment CenterRenji Hospital Affiliated to Shanghai Jiaotong University School of MedicineShanghai 200127China Department of Nephrology Shanghai Pudong New Area Punan HospitalShanghai 200125China Department of Nephrology Ningbo Hangzhou Bay HospitalNingbo 315336Zhejiang ProvinceChina

Background:Yiqi Peiyuan(YQPY)prescription,a composite prescription of traditional Chinese medicine,has been used to prevent or delay the continued deterioration of renal function after acute kidney injury(AKI)in some institutions and has shown considerable ***:This is the first randomized controlled trial to assess efficacy and safety of YQPY for improving short-term prognosis in adult patients with ***,setting,participants and interventions:This is a prospective,double-blind,multicenter,randomized,and placebo-controlled clinical trial.A total of 144 enrolled participants were randomly allocated to two groups according to a randomization ***,caregivers and investigators assessing the outcomes were blinded to group *** in the YQPY group received 36 g YQPY granules twice a day for 2. *** in the placebo group received a placebo in the same dose as the YQPY *** outcome measures:The primary outcome was the change in the estimated glomerular filtration rate(eGFR)between baseline and after 4 and 2. weeks of *** secondary outcomes were the change of serum creatinine(Scr)level between baseline and after treatment,and the incidence of endpoint events,defined as eGFR increasing by more than 2.%above baseline,eGFR>75 mL/min per1.73 m2.r the composite endpoint,which was defined as the sum of patients meeting either of the above ***:Data from a total of 114 patients(59 in the YQPY group and 55 in the control group)were *** mean changes in eGFR and Scr in weeks 4 and 2. had no difference between the two *** further subgroup analysis(2. in the YQPY group and 31 in the control group),the mean change in eGFR after treatment for 4 weeks was 2..39 mL/min per 1.73 m2.n the YQPY group and 5.78 mL/min per1.73 m2.n the placebo group,and the mean difference between groups was 2..61 mL/min per 1.73 m2.P<0.001).Thirteen(59.1%)patients in the YQPY group and 5(16.1%)in the placebo g

关键词： Chinese herbal medicine Randomized controlled trial Acute kidney injury Renal function

Frontiers in high entropy alloys and high entropy functional materials

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Rare Metals 2024年第10期43卷 4639-4776页

作者： Wen-Tao Zhang Wen Huang Fu-Jie Yu Qi Zhao Xin-Dong zhu Tao Feng Yao {2.g Xiao-Ming Li Xue-Fei Miao He zhu Si Lan Xue-Qian Wang Bao-Long shen Zhe Jia Feng-Qi Zhang Wei Wang Qi Liu yang Ren Xun-Li Wang Xiao-Ya Cui Xiao-yang Wang Ya-Nan Chen Bing-Bing Fan Meng-Ru Li Qi-Long Gao Jia-Ming Guo Zeng-Bao Jiao Zhi-Min Guo Yu-Ping Zhao Qian Yu Rui Huang Ling-Kun Zhang Yi-Ping Lu Xu-Bo Li Huai-Jun Lin yan Ma Wei-Ming yang Zhi-Hua shen Hai-yan He Yong-Gang Sun Yong-{2.g Huang De-zhuang Wang Qing-Feng Liu Fei-yang Wang Hui Liu Hong-Hui Wu Li-Qiang Wang yang Lu Nan Wang Tian-Li Wang Wei-Bing Liao Yi-han Wang Yuan Wu Yu-Zhen Yin Jie Pan Yi Zhang Qing Wang {2.-yang Zhang Tao yang Yasir Sohail Jin-Yu Zhang Hua Ji Qiang Li Wei-Di Liu Zhi-Gang Chen Xiong-Jun Liu Wen Ma Liang Mao Zhen-Duo Wu School of Materials Science and Engineering Nanjing University of Science and Technology jiangsu Key Laboratory for Advanced Metallic Materials School of Materials Science and Engineering Southeast University Department of Physics City University of Hong Kong School of Materials Science and Engineering Tianjin University School of Physics and Microelectronics Zhengzhou University Department of Mechanical Engineering Research Institute for Advanced Manufacturing The Hong Kong Polytechnic University Center of Electron Microscopy and State Key Laboratory of Silicon Materials School of Materials Science and Engineering Zhejiang University Key Laboratory of Solidification Control and Digital Preparation Technology (Liaoning Province) School of Materials Science and Engineering Dalian University of Technology Institute of Advanced Wear & Corrosion Resistance and Functional Materials Jinan University School of Mechanics and Civil Engineering China University of Mining and Technology School of Physical Sciences Great Bay University School of Materials Science andEngineering Harbin Institute of Technology State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical Engineering Nanjing Tech University Beijing Advanced Innovation Center for Materials Genome Engineering Research Institute for Carbon Neutrality University of Science and Technology Beijing Department of Mechanical Engineering The University of Hong Kong School of Computing Macquarie University Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic Engineering Shenzhen University State Key Laboratory for Advanced Metals and Materials University of Science and Technology Beijing State Key Laboratory of Materials Processing and Die & Mould Technology School of Materials Science and Engineering Huazhong University of Science and Technology Institute of materials Shanghai University Department of Materials Science and Engineering C

Owing to their exceptional properties, high-entropy alloys(HEAs) and high-entropy materials have emerged as promising research areas and shown diverse applications. Here,the recent advances in the field are comprehensively reviewed,organized into five sections. The first section introduces the background of HEAs, covering their definition, significance,application prospects, basic properties, design principles, and microstructure. The subsequent section focuses on cutting-edge high-entropy structural materials, highlighting developments such as nanostructured alloys, grain boundary engineering,eutectic systems, cryogenic alloys, thin films, micro-nano-lattice structures, additive manufacturing, high entropy metallic glasses, nano-precipitate strengthened alloys, composition modulation, alloy fibers, and refractory systems. In the following section, the emphasis shifts to functional materials, exploring HEAs as catalysts, magneto-caloric materials, corrosion-resistant alloys, radiation-resistant alloys, hydrogen storage systems, and materials for biomedicine. Additionally, the review encompasses functional high-entropy materials outside the realm of alloys, including thermoelectric, quantum dots, nanooxide catalysts, energy storage materials, negative thermal expansion ceramics,and high-entropy wave absorption materials. The paper concludes with an outlook, discussing future directions and potential growth areas in the field. Through this comprehensive review,researchers, engineers, and scientists may gain valuable insights into the recent progress and opportunities for further exploration in the exciting domains of high-entropy alloys and functional materials.

关键词： Cutting-edge structural materials Cutting-edgefunctional materials High entropy alloys

Status of aquatic organisms resources and their environments in yangtze River system(2.17-2.2.)⋆

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Aquaculture and Fisheries 2024年第5期9卷 833-850页

作者： Haile yang Li shen Yongfeng He Huiwu Tian Lei Gao Jinming Wu Zhigang Mei Nian Wei Lin Wang Tingbing {2. Feifei Hu Jinling Gong Hongchun Du Xinbin Duan Huatang Deng Daoqun Wang Fengyue {2. Yunfeng Li Fan Wu Huijun Ru yan Zhang Junyi Li Junlin yang Yuntao Zhou Dongdong Fang Yinping Wang Danqing Lin yanping yang Peijie Li Silei Liu jian yang Ping {2.ang Sikai Wang Tao Zhang Gang yang Wenbo yang Lilai Yuan Kun Cao Shuo Xu Huiyuan Liu Zhiqiang Liang Chongrui Wang Hong Li Xiping Yuan Xin yang Yilong Fu yanping Zhang Haixin Zhang Zhiying Tao sheng Wang Xiaoping Gao Binsong Jin Kemao Li Guojie Wang shenglong jian Yingqin Li Chenjiang Xue Chunyun Lei Shaowei Xue Yi Sun Bin {2. Ke Shao Xingkun Hu Meihua Xiong Jun Du Bin He Tao yan Yingying Huang Yuanchao Zou Biwen Xie Yongming Wang Bin Li Fei Liu Yaoyao Zhang Fei Fan Zhijian Wang Jing Huang Haoran Gu Hailong Ge yan Dan yan Li Shuqiao Wang Chuang Zhang Lu Zhou Xue Wang sheng Zeng yan Xiang Xugang He jianhui Qin Chengxing Xia Jie Hou Yifu Shi Lifang Gao Zhiqiang {2. Hongbao shen Yun Du Xuejun Duan Jiawu Xiong Deguo yang Shaoping Liu Zhaohui Ni Hui Zhang Kai Liu Feng Zhao Yingren Li jianwei Wang Qiwei Wei yangtze River Fisheries Research Institute Chinese Academy of Fishery SciencesWuhan430223China Institute of Hydrobiology Chinese Academy of SciencesWuhan430072China Fishery Resource and Environment Research Center Chinese Academy of Fishery SciencesBeijing100141China Key Laboratory of Freshwater Fisheries and Germplasm Resources Utilization Ministry of Agriculture and Rural AffairsFreshwater Fisheries Research CenterChinese Academy of Fishery SciencesWuxi214081China East china Sea Fisheries Research Institute Chinese Academy of Fishery SciencesShanghai200090China Institute of Fisheries Engineering Chinese Academy of Fishery SciencesBeijing100141China Hunan Fisheries Science Institute Changsha410153China jiangxi Fisheries Research Institute Nanchang330039China Jiujiang Academy of Fishery Sciences Jiujiang332000China School of Life Sciences Nanchang UniversityNanchang330031China Qinghai Provincial Fishery Technology Extension Center Xining810012China Yunnan Academy of Fishery Sciences Kunming650111China Institute of Hydroecology Ministry of Water Resources and Chinese Academy of SciencesWuhan430079China Fisheries Institute Sichuan Academy of Agricultural SciencesChengdu611731China School of Life Sciences Neijiang Normal UniversityNeijiang641100China School of Life Sciences Southwest UniversityChongqing400715China Chongqing Fishery Sciences Research Institute Chongqing401120China Guizhou Fisheries Research Institute Guiyang550025China College of Fisheries Huazhong Agricultural UniversityWuhan430072China Hubei Fisheries Science Research Institute Wuhan430070China Shaanxi Fisheries Research Institute Xi’an710086China Innovation Academy for Precision Measurement Science and Technology Chinese Academy of SciencesWuhan430077China nanjing Institute of Geography and Limnology Chinese Academy of SciencesNanjing210008China Central South Inventory and Planning Institute of State Forestry and Grassland Administration Changsha410014China

The yangtze River is the mother river of *** promote the aquatic ecosystem protection of the great river,the Project of yangtze Fisheries Resources and Environment Investigation(2.17-2.2.)supported by the Ministry of Agriculture and Rural Affairs,*** carried out by 2. institutes and universities that located in the yangtze River basin surveys the status of(1)fish species composition and spatial distribution,(2.current fish abundance,(3)endangered fishes,(4)yangtze finless porpoise,(5)aquatic eco-environments,(6)water-level fluctuation areas,(7)capture fisheries and recreational fisheries of the yangtze River mainstream and 10 of its main tributaries,including Yalong River,Heng River,Min River(including Dadu River),Chishui River,Tuo River,Jialing River,Wu River,han River,Dongting Lake and Poyang *** results showed that there were 443 fish species(belonging to 163 genus,37 families,and 18 orders)before 2.17,but only 32. fish species(including 15 new recorded exotic species)were recorded in the project of *** them,Cyprinus carpio,Carassius auratus,Hypophthalmichthys molitrix,Pelteobagrus fulvidraco,Coilia brachygnathus,Silurus asotus,Saurogobio dabryi,Ctenopharyngodon idellus,Pelteobagrus nitidus,Hemiculter leucisculus,Siniperca chuatsi,Coreius heterodon,Culter alburnus,Parabramis pekinensis,and Aristichthys nobilis were the dominant species across the whole yangtze River *** is estimated that there were 886 million individuals weighing 12..8 million kg,merely equivalent to 2..3%of the resources in 1950s,30.9%of the resources in 1960s,or 58.7%of the resources in *** the new list of protected fishes that recorded in the yangtze River system,only 15 of 2. were collected in this project of *** gladius has been affirmed to be Extinct by International Union for Conservation of Nature(IUCN).The wild individuals of Tenualosa reevesii and Luciobrama macrocephalus have disappeared for many years and maybe have been extinct

关键词： Fishes yangtze finless porpoise Resources Aquatic ecosystem Fisheries Background investigation yangtze river system

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松孔镀铬缸套磨损机理研究

内燃机学报 2017年第3期35卷 274-279页

作者：朱峰徐久军孙健沈岩韩晓光大连海事大学船机修造工程交通行业重点实验室辽宁大连116026 中国船级社大连分社辽宁大连116021

采用往复式摩擦磨损试验机,从缸套、活塞环零件上切取试样开展试验,通过测量镀铬缸套的摩擦系数、磨损量,观察缸套磨损后形貌、磨粒形貌以及成分并与传统合金铸铁缸套对比,研究松孔镀铬缸套的磨损机理.结果表明:与铸铁缸套相比,镀铬缸... 详细信息

采用往复式摩擦磨损试验机,从缸套、活塞环零件上切取试样开展试验,通过测量镀铬缸套的摩擦系数、磨损量,观察缸套磨损后形貌、磨粒形貌以及成分并与传统合金铸铁缸套对比,研究松孔镀铬缸套的磨损机理.结果表明:与铸铁缸套相比,镀铬缸套可以大幅降低缸套磨损量,但摩擦系数略高,对活塞环磨损略大;镀铬缸套磨损后表面呈现点状微坑形貌,磨粒呈片状或薄片状;镀铬层的松孔附近在往复摩擦力的作用下萌生疲劳裂纹,裂纹沿表面平行于滑动方向扩展,直至延伸到表面脱落,形成磨粒,造成磨损.

关键词：松孔镀铬缸套磨粒磨损机理

The Influence of Diabetes, Hypertension, and Hyperlipidemia on the Onset of Age-Related Macular Degeneration in North china: The Kailuan Eye Study

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Biomedical and Environmental Sciences 2022年第7期35卷 613-621页

作者： ZhanG Yong Peng WANG Ya Xing ZHOU Jin Qiong WANG Qian yan yan Ni yanG Xuan yanG Jing yan ZHOU Wen Jia WANG Ping shen Chang yanG Ming LUAN Ya Nan WANG Jin Yuan WU Shou Ling CHEN Shuo Hua WANG Hai Wei FANG Li jian WAN Qian Qian zhu Jing Yuan NIE Zi han CHEN Yu Ning XIE Ying JONAS JB WEI Wen Bin Beijing Tongren Eye Center Beijing key Laboratory of Intraocular Tumor Diagnosis and TreatmentBeijing Ophthalmology&Visual Sciences Key LabMedical Artificial Intelligence Research and Verification Key Laboratoryof the Ministry of Industry and Information TechnologyBeijing Tongren HospitalCapital Medical UniversityBeijing 100730China Beijing Institute of Ophthalmology Beijing Key Laboratory of Ophthalmology and VisualSciencesBeijing Tongren Eye CenterBeijing Tongren HospitalCapital Medical UniversityBeijing 100730China Cardiology Department Kailuan General HospitalTangshan 063000HebeiChina Health CareCenter Kailuan GroupTangshan 063000HebeiChina Department of Opthalmology Fuxing HospitalCapitalMedical UniversityBeijing 100038China Beijing Liangxiang Hospital Capital Medical UniversityDepartmentof OphthalmologyBeijing 102401China Department of Ophthalmology The Second Hospital of Anhui MedicalUniversityHefei 230000AnhuiChina Department of Opthalmology Shanxi Provincial People's HospitalTaiyuan 030012ShanxiChina Department of Ophthalmology Medical Faculty Mannheim of the Ruprecht-Karls-University of HeidelbergHeidelbergGermany

Objective To analyze the prevalence of dry and wet age-related macular degeneration(AMD)in patients with diabetes,hypertension and hyperlipidemia,and to analyze the risk factors for *** A population-based cross-sectional epidemiologic study was conducted involving 14,440 *** assessed the prevalence of dry and wet AMD in diabetic and non-diabetic subjects and analyzed the risk factors for *** The prevalence of wet AMD in diabetic and non-diabetic patients was 0.3%and 0.5%,respectively,and the prevalence of dry AMD was 17%and 16.4%,*** prevalence of wet AMD in healthy,hypertensive,hyperlipidemic,and hypertensive/hyperlipidemic populations was 0.5%,0.3%,0.2.,and 0.7%,*** prevalence of dry AMD in healthy,hypertensive,hyperlipidemic,and hypertensive/hyperlipidemic populations was 16.6%,16.2.,15.2.,and 17.2.,***,sex,body mass index,and use of hypoglycemic drugs or lowering blood pressure drugs were corrected in the risk factor analysis of ***,diabetes/hypertension,diabetes/hyperlipidemia,and diabetes/hypertension/hyperlipidemia were *** of the factors analyzed in the current study increased the risk for the onset of *** There was no significant difference in the prevalence of wet and dry AMD among diabetic and non-diabetic ***,there was no significant difference in the prevalence of wet and dry AMD among subjects with hypertension and *** co-existing with hypertension and hyperlipidemia were not shown to be risk factors for the onset of dry AMD.

关键词： Diabetes Hypertension Hyperlipidemia Age-related macular degeneration Prevalence Risk factor

一种气隙磁导谐波引起的永磁体涡流损耗的解析计算方法

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电机与控制学报 2020年第5期24卷 10-16,25页

作者：朱龙飞祝天利于慎波韩雪岩朱建国沈阳工业大学国家稀土永磁电机工程技术研究中心沈阳110870 悉尼科技大学电气机械和机电系统学院新南威尔士州悉尼2007

针对3D有限元软件计算永磁电机永磁体涡流损耗耗时长,永磁体涡流损耗精确解析模型复杂,参数变量间对应关系不明晰等问题,采用槽口位置的局部解析建模方法,重新建立坐标系,研究与槽口位置对应的永磁体内磁密变化规律,并对磁密波形进行简... 详细信息

针对3D有限元软件计算永磁电机永磁体涡流损耗耗时长,永磁体涡流损耗精确解析模型复杂,参数变量间对应关系不明晰等问题,采用槽口位置的局部解析建模方法,重新建立坐标系,研究与槽口位置对应的永磁体内磁密变化规律,并对磁密波形进行简化分析,提出一种气隙磁导谐波引起的永磁体涡流损耗的简化解析计算模型,该方法可直观反映出永磁体涡流损耗的主要影响因素,且计算耗时短。利用3D有限元和实验结果对该简化解析模型计算结果进行验证。基于该简化解析模型分析得出影响槽口位置永磁体磁密变化的主要因素为槽口宽度与等效气隙长度之比和槽口宽度与定子齿距之比,进而研究了主要影响因素对气隙磁导谐波引起的永磁体涡流损耗的影响规律,并提出相应的参数优化方法。结果显示,优化后样机永磁体涡流损耗降低了90.2.,损耗抑制效果十分明显。

关键词：磁导谐波解析法涡流损耗永磁电机

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基于循环经济的毛竹产业链设计

浙江大学学报（工学版） 2008年第12期42卷 2187-2191页

作者：张颖心沈剑韩艳王霏娜朱明乔浙江大学化学工程与生物工程学系浙江杭州310027

为改变我国毛竹产业高消耗、低效率、粗放型经营的现状,以循环经济理念为指导,对毛竹产业进行了产业链设计.产业链以毛竹资源的深加工为主线,构建了从毛竹林培育、鲜笋加工到毛竹全株利用的产业体系,形成了多层次的产品结构;设计了一条... 详细信息

为改变我国毛竹产业高消耗、低效率、粗放型经营的现状,以循环经济理念为指导,对毛竹产业进行了产业链设计.产业链以毛竹资源的深加工为主线,构建了从毛竹林培育、鲜笋加工到毛竹全株利用的产业体系,形成了多层次的产品结构;设计了一条生产竹叶黄酮的清洁工艺,对竹炭生产中产生的余热进行了合理的利用,并对各生产流程中的部分环节进行了工艺的选择;通过笋竹两用林、笋制品厂、竹叶黄酮厂、竹材人造板厂、竹炭厂、手工厂和饲料厂之间物质交换、能量和水的高效利用,基本实现了物质和能量的闭路循环.所设计的产业链低消耗、低排放、高效率,是一种毛竹产业可持续发展的模式.

关键词：毛竹产业链设计竹叶黄酮竹炭循环经济

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高承载力盾构管片接头预埋件抗拉性能试验

中国公路学报 2017年第8期30卷 149-155页

作者：朱建文孟晗闫治国周龙朱合华官林星沈奕同济大学土木工程学院上海200092 同济大学土木工程防灾国家重点实验室上海200092 上海市政工程设计研究总院(集团)有限公司上海200092

为了选择适用于软土地区深埋排水盾构隧道管片接头结构形式,针对新型高承载力盾构隧道管片接头预埋件结构,开展了1∶1结构抗拉性能试验,研究管片接头预埋件在不同荷载工况下,锚筋的应力分布和传递、接头板的变形和位移、螺栓的应力分布... 详细信息

为了选择适用于软土地区深埋排水盾构隧道管片接头结构形式,针对新型高承载力盾构隧道管片接头预埋件结构,开展了1∶1结构抗拉性能试验,研究管片接头预埋件在不同荷载工况下,锚筋的应力分布和传递、接头板的变形和位移、螺栓的应力分布、管片混凝土裂缝的分布扩展情况和结构最终破坏模式等力学特征。研究结果表明:锚筋应力随着与预埋件连接处距离的增加逐步减小,且传递曲线均呈现出先陡后缓的趋势;接头预埋件锚板和锚筋的存在,使得接头的整体刚度得到了增强,同时提高了结构的承载能力;结构最终破坏模式是接头预埋件与锚筋的连接位置发生断裂破坏,且结构破坏时预埋件整体有较大的翘曲变形,因此可以考虑提高预埋件与锚筋的连接性能并相应增加预埋件的刚度以进一步改善结构的整体性能。

关键词：盾构隧道抗拉性能足尺试验预埋件高承载力

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong jianin AGH university of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui university HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu university Institute of ScienceVaranasi Bandirma Onyedi Eylul university Bandirma Beihang university Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal university Beijing Brown university ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad university Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo university Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central china Normal university WuhanHubei Central South university ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan china academy of engineering physics MianyangSichuan china building materials academy Beijing china Center of Advanced Science and Technology Beijing china Institute of Atomic Energy Beijing china Jiliang university HangzhouZhejiang china Nuclear Instrument CO. LTDBeijing china university of Geosciences Beijing china university of Geosciences WuhanHubei china university of Mining and Technology XuzhouJiangsu china West Normal university NanchongSichuan Chongqing university Department of PhysicsChongqing Chulalongkorn university Bangkok City university of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell university IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu university DalianLiaoning Dalian university of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East china university Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by china,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2.s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2.15)and the Conceptual Design Report(CDR,2.18),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2.2.-2.2.,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2.30s.

关键词： initiated exceeding precise