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Advances in ethnopharmacology,phytochemistry and pharmacology of Erigerontis Herba and its Chinese medicine prescriptions

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Traditional Medicine Research 2025年第1期10卷 44-61页

作者： yang Zhou yuan-yan Huang Ding-Yue Shang Ying Chen Meng Tian Cheng-Yu Jin Xin Lu Bing-Chun yan Han-Qing Pang Institute of Translational Medicine School of MedicineYangzhou UniversityYangzhou 225009China Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases Yangzhou UniversityYangzhou 225009China School of Medicine Nanjing University of Chinese MedicineNanjing 210023China State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources Guangxi Normal UniversityGuiling 541004China.

Erigerontis Herba(EH),the dried whole plant of Erigeron breviscapus,is well-known for circulating blood,activating meridians to alleviate pain,expelling wind,and clearing away *** has been extensively utilized in southern China for the treatment of stroke hemiplegia,chest stuffiness and pains,rheumatic arthralgia,headache,and *** review focuses on the botany,ethnopharmacology,phytochemistry,pharmacology and toxicity of EH and its related prescriptions to offer new insights for prospective research of *** information about EH was retrieved from ancient records and books,PubMed,China National Knowledge Infrastructure,Chinese Pharmacopoeia,Web of Science,Doctoral and Master’s Theses,and various electronic *** is a member of Compositae family and is mainly grown in southern *** Chinese medicine records that EH has the effects of circulating blood and removing blood stasis,expelling wind,and removing cold,as well as relieving rigidity of muscle and relieving *** now,nearly 200 ingredients have been characterized from EH,including flavonoids,caffeoyls,aromatic acids,coumarins,pentacyclic terpenoids,volatile oil and other *** extracts,EH related prescriptions(Dengzhan Xixin injection,Dengzhan Shengmai capsules,etc.)or compounds(scutellarin,scutellarein,etc.)possessed obvious therapeutic effects of ischemic stroke,cerebral hemorrhage,myocardial infarction,Alzheimer’s disease,diabetes and its complications,gastric cancer,bone,and joint degenerative ***,the major active compound of EH,has been used as a quality *** no obvious toxicity of EH has been *** to its traditional applications,ethnopharmacology,phytochemistry,pharmacology,and toxicity,EH was applied as a valuable herb for clinical application in food and medicine *** several compounds have been shown to possess diverse biological activities,the underlying mechanisms of their actions remain *** fully exploi

关键词： Erigeron breviscapus traditional applications ethnopharmacology phytochemistry pharmacology

BNIP3L介导的线粒体自噬在镉致大鼠大脑皮质神经元凋亡中的作用

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畜牧与兽医 2025年第1期57卷 50-56页

作者：闻双全王亮方兰袁燕苏州健雄职业技术学院江苏太仓215411 扬州大学兽医学院江苏扬州225009 江苏高校动物重要疫病与人兽共患病防控协同创新中心江苏扬州225009

为探究线粒体自噬受体Bcl-2/腺病毒E1B 19 kDa相互作用蛋白3样(BNIP3L)介导的线粒体自噬对镉致大鼠大脑皮质神经元凋亡的调控作用,利用RNA干扰技术建立大鼠大脑皮质神经元BNIP3L基因沉默模型,并经10μmol/L镉处理12 h,Western blot检测B... 详细信息

为探究线粒体自噬受体Bcl-2/腺病毒E1B 19 kDa相互作用蛋白3样(BNIP3L)介导的线粒体自噬对镉致大鼠大脑皮质神经元凋亡的调控作用,利用RNA干扰技术建立大鼠大脑皮质神经元BNIP3L基因沉默模型,并经10μmol/L镉处理12 h,Western blot检测BNIP3L、帕金森氏蛋白2(Parkin)和线粒体凋亡通路相关蛋白cleaved caspase-9、cleaved caspase-3的表达水平,免疫荧光染色检测BNIP3L与线粒体标志蛋白TOMM20共定位,透射电镜检测细胞内线粒体自噬体数目,FITC Annexin V染色检测细胞凋亡水平。结果:大鼠大脑皮质神经元经镉处理12 h后,BNIP3L蛋白表达水平极显著升高(P<0.01),BNIP3L与TOMM20共定位增加,沉默BNIP3L极显著抑制镉致Parkin线粒体转位(P<0.01),抑制镉致细胞内线粒体自噬体形成,极显著促进镉致caspase-9、caspase-3激活和神经元凋亡(P<0.01)。结果表明,BNIP3L介导的线粒体自噬可抑制镉致大鼠大脑皮质神经元凋亡。

关键词：镉大鼠大脑皮质神经元 BNIP3L 线粒体自噬凋亡

Soliton Rectangular Pulses and Bound States in a Dissipative System Modeled by the Variable-Coefficients Complex Cubic-Quintic Ginzburg-Landau Equation

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Chinese Physics Letters 2021年第9期38卷 48-51页

作者： yuan-yuan yan Wen-Jun Liu State Key Laboratory of Information Photonics and Optical Communications School of ScienceBeijing University of Posts and TelecommunicationsBeijing 100876China

The complex cubic-quintic Ginzburg-Landau equation(CQGLE)is a universal model for describing a dissipative system,especially fiber *** analytic one-soliton solution of the variable-coefficients CQGLE is calculated by a modified Hirota ***,phenomena of soliton pulses splitting and stable bound states of two solitons are ***,rectangular dissipative soliton pulses of the variable-coefficients CQGLE are realized and controlled effectively in the theoretical research for the first time,which breaks through energy limitation of soliton pulses and is expected to provide theoretical basis for preparation of high-energy soliton pulses in fiber lasers.

关键词： method soliton dissipative

Influence of seasonal temperature change on autotrophic nitrogen removal for mature landfill leachate treatment with high-ammonia by partial nitrification-Anammox process

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Journal of Environmental Sciences 2021年第4期33卷 291-300页

作者： Xiang Li Ming-yu Lu Yong Huang Yi yuan yan yuan School of Environmental Science and Engineering Suzhou University of Science and TechnologySuzhou 215009China National and Local Joint Engineering Laboratory of Municipal Sewage Resource Utilization Technology Suzhou 215009China

In this study,a denitrification(DN)–partial nitritation(PN)–anaerobic ammonia oxidation(Anammox)system for the efficient nitrogen removal of mature landfill leachate was built with a zone-partitioning self-reflux biological reactor as the core device,and the effects of changes in seasonal temperature on the nitrogen removal in non-temperature-control environment were *** results showed that as the seasonal temperature decreased from 34℃to 11.3℃,the total nitrogen removal rate of the DN-PN-Anammox system gradually decreased from the peak value of 1.42 kg/(m^(3)·day)to 0.49 kg/(m^(3)·day).At low temperatures(<20℃),when the nitrogen load(NLR)of the system is not appropriate,the fluctuation of high NH_(4)^(+)-N concentration in the landfill leachate greatly influenced the stability of the nitrogen *** temperatures of 11℃–15℃,the NLR of the system is controlled below 0.5 kg/(m^(3)·day),which can achieve stable nitrogen removal and the nitrogen removal efficiency can reach above 96%.The abundance of Candidatus Brocadia gradually increased with the decrease of ***,Candidatus Brocadia and Candidatus Kuenenia as the main functional microorganisms in the low temperature.

关键词： Landfill leachate Denitrification-partial nitrification-Anammox Seasonal temperature Nitrogen removal Microbiology community

Effect of Long-Term Fertilization on Soil Productivity on the North China Plain

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Pedosphere 2015年第3期25卷 450-458页

作者： WANG Jing-yan yan Xiao-yuan GONG Wei Sichuan Provincial Key Laboratory of Ecological Forestry Engineering Sichuan Agricultural University State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of Sciences

Soil productivity is the ability of a soil, in its normal environment, to support plant growth and can be evaluated with respect to crop production in unfertilized soil within the agricultural ecosystem. Both soil productivity and fertilizer applications affect crop yields. A long-term experiment with a winter wheat-summer maize rotation was established in 1989 in a field of the Fengqiu State Key Agro-Ecological Experimental Station, a region typical of the North China Plain, including seven treatments： 1） a balanced application of NPK chemical fertilizers （NPK）; 2） application of organic fertilizer （OM）; 3） application of 50% organic fertilizer and 50% NPK chemical fertilizers （1/2OMN）; 4） application of NP chemical fertilizers （NP）; 5） application of PK chemical fertilizer （PK）; 6） application of NK chemical fertilizers （NK）; and 7） unfertilized control （CK）. To investigate the effects of fertilization practices on soil productivity, further pot tests were conducted in 2007-2008 using soil samples from the different fertilization treatments of the long-term field experiment. The soil sample of each treatment of the long-term experiment was divided into three pots to grow wheat： with no fertilization （Potunf）, with balanced NPK fertilization （POtNPK）, and with the same fertilizer（s） of the long-term field experiment （Potori）. The fertilized soils of the field experiment used in all the pot tests showed a higher wheat grain yield and higher nutrient uptake levels than the unfertilized soil. Soil productivity of the treatments of the field experiment after 18 years of continuous fertilizer applications were ranked in the order of OM 〉 1/2OMN 〉 NPK 〉 NP 〉 PK 〉 NK 〉 CK. The contribution of soil productivity of the different treatments of the field experiment to the wheat grain yield of Potori was 36.0%-76.7%, with the PK and NK treatments being higher than the OM, 1/2OMN, NPK, and NP treatments since the soil in this area was deficient in N and P and rich in K. Wheat g

关键词： balanced fertilization chemical fertilizer crop yield soil fertility nutrient use efficiency organic fertilizer soil organic matter

Climatic implications in earlywood and latewood width indices of Chinese pine in north central China

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Journal of Forestry Research 2024年第3期35卷 143-153页

作者： Kaixuan yang Junzhou Zhang Haowen Fan yuan yan College of Geographic Sciences Qinghai Normal UniversityXining 810016People's Republic of China Key Laboratory of Tibetan Plateau Land Surface Processes and Ecological Conservation(Ministry of Education) Xining 810016People's Republic of China Key Laboratory of Western China's Environmental Systems(Ministry of Education) College of Earth and Environmental SciencesLanzhou UniversityLanzhou 730030People's Republic of China Gansu Liancheng Forest Ecosystem Field Observation and Research Station Lanzhou UniversityLanzhou 730333People's Republic of China School of Geography and Information Engineering University of GeoscienceWuhan 430074People's Republic of China

Latewood width(LWW)indices of trees are considered a reliable proxy of summer precipitation in the Northern ***,the strong coupling and high correlation between earlywood width(EWW)and LWW indices often prevent registration of climate signals of the LWW *** this study,328-year-long earlywood width and latewood width chronologies were developed from Chinese pine at two sites in the Hasi Mountains,north central *** climate responses of these chronologies were analyzed and the LWW index used to derive sum-mer precipitation *** analyses showed that LWW was particularly influenced by earlywood growth and recorded stronger climate signals of the previous year as EWW,rather than those of the current year with infrequent summer climate ***,after removing the effect of earlywood growth using a simple regression model,the adjusted LWW chronology(LWW_(adj))showed a strong relationship with July precipitation in dry *** suggests that the LWW_(adj) chronology has the potential to be used to investigate long-term variability in summer precipitation in drought-limited regions.

关键词： Dendroclimatology Latewood width Climate response Summer precipitation Earlywood effect

Automatic generation of optical initial configuration based on Delano diagram

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Research in Astronomy and Astrophysics 2016年第1期16卷 59-66页

作者： Kai-yuan Zhang Xiang-yan yuan Xiang-Qun Cui National Astronomical Observatories/Nanjing Institute of Astronomical Optics & Technology Nanjing 210042 China Key Laboratory of Astronomical Optics & Technology Nanjing Institute of Astronomical Optics & Technology Chinese Academy of Sciences Nanjing 210042 China University of Chinese Academy of Sciences Beijing 100049 China

This paper presents a method to automatically initialize an optical system based on the Delano diagram. The process to generate the optical initial configuration is constrained by the control points, which are deduced from parameters related to basic design requirements. We present the theory and method to generate the optical initial configuration automatically when the basic design requirements are known. Two optical systems are taken as examples to demonstrate the proposed method.

关键词： telescopes -- methods: analytical

Graph partitioning algorithm for opportunistic routing in large-scale wireless network

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The Journal of China Universities of Posts and Telecommunications 2009年第4期16卷 42-46页

作者： LI yan-hua LIU yuan-an Wireless Communication Center Beijing University of Posts and Telecommunications Beijing 100876 China

Opportunistic routing takes advantage of the broadcast nature of wireless communications by forwarding data through a set of opportunistic paths instead of one ＇best＇ path in traditional routing. However, using the global scheduling opportunistic scheme like the existing opportunistic routing protocol （ExOR） would consume considerable transmission latency and energy in large-scale wireless topologies. In this article, a graph partitioning algorithm is proposed, namely, minimum cut with laplacians （MCL）, to divide the Ad-hoc network topology into subgraphs with minimized edge cuts across them. Then the existing opportunistic routing can be applied locally in each subgraph. In this way, forwarders in different subgraphs can transmit simultaneously, and each node only needs to maintain a local forwarder list instead of a global one. The simulations show that using MCL scheme in the opportunistic routing can reduce the end-to-end delay by about 49%, and increase the life time of the wireless node by about 39%.

关键词： opportunistic routing graph partitioning wireless routing mobile Ad-hoc network

Recent advances in molecular biology research of a rice pest, the brown planthopper

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Journal of Integrative Agriculture 2019年第4期18卷 716-728页

作者： BAO yan-yuan ZHANG Chuan-xi State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects Institute of Insect Sciences Zhejiang University

The brown planthopper, Nilaparvata lugens St?l, has become a major threat in tropical Asian and China since the rice green revolution of the 1960 s. Currently, insecticide application remains the primary choice for controlling this rice insect pest, but heavy use of insecticides poses dangerous risks to beneficial natural enemies and pollinators, and stimulates N. lugens reproductivity, and has caused a resurgence of the pest in the major rice-planting regions throughout Asia. Achieving the long-lasting goal of sustainable management of N. lugens requires understanding of the molecular basis of outbreaks of the pest and the development of environment-friendly pest-control strategies. Here, we review the recent molecular advances in N. lugens research on the aspects of its endosymbionts, virus transmission, insecticide resistance, and interaction between N. lugens and rice plants. We also put forward further research directions that may shed some lights on management of the rice pest.

关键词： Nilaparvata lugens endosymbionts virus transmission insecticide resistance interaction with rice biological management