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Influence and optimization of swirler parameters on elbow wear of deep coal fluidization pipeline transportation system

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Friction 2024年第7期12卷 1408-1433页

作者： Shaodi ZHAO Jiusheng BAO Shirong GE Zhongbin WANG yan yin Congguang HUANG School of Mechanical and Electrical Engineering China University of Mining and TechnologyXuzhou 221116China School of Mechanical Electronic and Information Engineering China University of Mining and Technology-BeijingBeijing 100083China Frontier Scientific Research Center for Fluided Mining of Deep Underground Resources China University of Mining and TechnologyXuzhou 221008China

Elbow wear is a major threat to the multiphase pipeline transportation industry,which has a negative impact on the stable operation of the transportation *** order to find the wear reduction methods of elbows in the fluidization pipeline transportation system for 2000-meter-deep coal resources,the swirler was installed upstream of the elbows,and wear simulations and tests of three kinds of elbows were carried *** results showed that the maximum wear rate(MWR)of elbows increased and then decreased along the elbow *** to the different directions of gravity,the heavy wear position(HWP)of the horizontal-vertical(H-V)elbow was in front of the vertical-horizontal(V-H)*** the downstream portion of the horizontal-horizontal(H-H)elbow was still a horizontal pipe,the HWP of the H-H elbow almost covered the whole *** swirler placed upstream of the elbows could make the particles at the elbow move to the intrados of the elbows,resulting in less collision between the particles and the extrados of the elbows,thus reducing the wear of the *** wear reduction effects of swirlers on three different elbows were favorably connected with the guide vane angle(GVA)and negatively correlated with the guide vane length(GVL),decreased first and then increased as the guide vane height(GVH)increased,and were little affected by the guide vane number(GVN)and the guide vane thickness(GVT).The mathematical models between the MWR of the elbows and guide vane parameters were *** bench tests,the wear reduction effect of three kinds of elbows under the optimal guide vane parameters was 58.4%,76.9%,and 78.6%,*** errors between the bench test results and the simulation results were around 10%.

关键词： pipe elbow erosion wear spiral flow swirler guide vane parameters particle collision

Status quo and factors of depression and anxiety in patients with non-muscle invasive bladder cancer after plasma electrocision

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World Journal of Psychiatry 2024年第6期14卷 822-828页

作者： Bing Lu Meng Ding Hong-Bo Xu Chun-yin yan Department of Urology Suzhou Dushu Lake HospitalSuzhou 215000Jiangsu ProvinceChina Department of Urology The First Affiliated Hospital of Soochow UniversitySuzhou 215000Jiangsu ProvinceChina

BACKGROUND Bladder cancer is a type of cancer with a high incidence in *** electrosurgery(PES)is often used in the treatment of bladder *** complications often cause depression and anxiety in patients after *** To investigate the current state of depression and anxiety after PES in patients with non-muscle-invasive bladder cancer and analyze the factors affecting *** A retrospective study was conducted to compare the baseline data of patients by collecting their medical history and grouping them according to their mental status into negative and normal *** regression analysis was used to explore the risk factors affecting the occurrence of anxiety and depression after surgery in patients with bladder *** Comparative analyses of baseline differences showed that the patients in the negative and normal groups differed in terms of their first surgery,economic status,educational level,and marital status.A logistic regression analysis showed that it affected the occurrence of anxiety in patients with bladder cancer,and the results showed that whether the risk factors were whether or not it was the first surgery,monthly income between 3000 and 3000-6000,secondary or junior high school education level,single,divorced,and widowed *** The risk factors affecting the onset of anxiety and depression in bladder cancer patients after PES are the number of surgeries,economic status,level of education,and marital *** study provides a reference for the clinical treatment and prognosis of bladder cancer patients in the future.

关键词： Bladder cancer Anxiety Depression Analysis of influencing factors Plasma electrocision

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Neural Regeneration Research 2025年第2期20卷 366-377页

作者： Samuel Abokyi Dennis yan-yin Tse School of Optometry The Hong Kong Polytechnic UniversityKowloonHong Kong Special Administrative RegionChina Research Center for SHARP Vision The Hong Kong Polytechnic UniversityKowloonHong Kong Special Administrative RegionChina Center for Eye and Vision Research Sha TinHong Kong Special Administrative RegionChina

Retinal aging has been recognized as a significant risk factor for various retinal disorders,including diabetic retinopathy,age-related macular degeneration,and glaucoma,following a growing understanding of the molecular underpinnings of their *** comprehensive review explores the mechanisms of retinal aging and investigates potential neuroprotective approaches,focusing on the activation of transcription factor *** meta-analyses have demonstrated promising outcomes of transcription factor EB-targeted strategies,such as exercise,calorie restriction,rapamycin,and metformin,in patients and animal models of these common retinal *** review critically assesses the role of transcription factor EB in retinal biology during aging,its neuroprotective effects,and its therapeutic potential for retinal *** impact of transcription factor EB on retinal aging is cell-specific,influencing metabolic reprogramming and energy homeostasis in retinal neurons through the regulation of mitochondrial quality control and nutrient-sensing *** vascular endothelial cells,transcription factor EB controls important processes,including endothelial cell proliferation,endothelial tube formation,and nitric oxide levels,thereby influencing the inner blood-retinal barrier,angiogenesis,and retinal ***,transcription factor EB affects vascular smooth muscle cells,inhibiting vascular calcification and *** retinal pigment epithelial cells,transcription factor EB modulates functions such as autophagy,lysosomal dynamics,and clearance of the aging pigment lipofuscin,thereby promoting photoreceptor survival and regulating vascular endothelial growth factor A expression involved in *** cell-specific functions of transcription factor EB significantly impact retinal aging mechanisms encompassing proteostasis,neuronal synapse plasticity,energy metabolism,microvasculature,and inflammation,ultimately offering pro

关键词： age-related macular degeneration anti-aging interventions autophagy calorie restriction diabetic retinopathy exercise glaucoma neuromodulation phagocytosis photoreceptor outer segment degradation retinal aging transcription factor EB

Complementary multicolor electrochromic devices with excellent stability based on porous tin oxide nanosheet scaffold

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Nano Research 2024年第4期17卷 3035-3042页

作者： Chenchen Bian Jinhui Wang Huanhuan Liu yin yan Ping Zhang Weilong yang Sensen Jia Xiaodan Guo Guofa Cai Key Laboratory for Special Functional Materials of Ministry of Education National&Local Joint Engineering Research Center for High-Efficiency Display and Lighting TechnologySchool of Materials and Engineeringand Collaborative Innovation Center of Nano Functional Materials and ApplicationsHenan UniversityKaifeng 475004China

Electrochromic devices(ECDs)have been extensively investigated as promising candidates in broad cutting-edge applications,such as smart windows,electronic labels,adaptive camouflage,***,they have suffered from either inadequate color variations or poor cycling stability for a long ***,we developed a general strategy to boost the cyclic stability and enrich the color variations of ECDs by scrupulous design of the composition and nanostructure of electrodes,in which porous tin oxide(SnO_(2))nanosheets serve as the scaffold and typical metal oxides or conducting polymers as the active electrochromic *** electrochromic composite materials,including polyaniline(PANI)@SnO_(2),V2O5@SnO_(2),and WO_(3)@SnO_(2) heterostructured nanoarrays were prepared by the facile wet-chemical *** composite electrodes exhibit remarkable electrochromic performances,e.g.,superior cycling stability(more than 2000 cycles),rich color variations(more than 5 colors for PANI@SnO_(2)),and enlarged optical *** excellent performances account for the heterogenous porous nanoarrays,which not only facilitate the intercalation/extraction of ions but also relieve the stress generated during the electrochemical *** addition,diverse prototypes of complementary multicolor ECD with excellent cycling stability(over thousands of cycles)and rich color variations(8 colors)were realized for the first *** believe that our work put forward a general strategy for developing high-quality multicolor complementary electrochromic devices.

关键词： electrochromism tin oxide metal oxide cycling stability multicolor complementary device

The light and hypoxia induced gene ZmPORB1 determines tocopherol content in the maize kernel

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Science China(Life Sciences) 2024年第3期67卷 435-448页

作者： Nannan Liu Yuanhao Du Shijuan yan Wei Chen Min Deng Shutu Xu Hong Wang Wei Zhan Wenjie Huang yan yin Xiaohong yang Qiao Zhao Alisdair R.Fernie Jianbing yan National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural UniversityWuhan 430070China Hubei Hongshan Laboratory Wuhan 430070China Agro-biological Gene Research Center Guangdong Academy of Agricultural SciencesGuangzhou 510640China College of Agronomy Hunan Agricultural UniversityChangsha 410128China College of Agronomy Northwest A&F UniversityXi'an 710000China State Key Laboratory of North China Crop Improvement and Regulation Hebei Sub-center of National Maize Improvement Center of ChinaCollege of AgronomyHebei Agricultural UniversityBaoding 071001China College of Life Sciences South-Central Minzu UniversityWuhan 430070China Plant Science Facility of the Institute of Botany Chinese Academy of SciencesBeijing 100093China National Maize Improvement Center of China Beijing Key Laboratory of Crop Genetic ImprovementChina Agricultural UniversityBeijing 100093China Shenzhen Key Laboratory of Synthetic Genomics Guangdong Provincial Key Laboratory of Synthetic GenomicsShenzhen Institute of Synthetic BiologyShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China Max Planck Institute of Molecular Plant Physiology Potsdam-Golm 14476Germany

Tocopherol is an important lipid-soluble antioxidant beneficial for both human health and plant growth. Here, we fine mapped a major QTLqVE1 affecting γ-tocopherol content in maize kernel, positionally cloned and confirmed the underlying gene ZmPORB1(por1), as a protochlorophyllide oxidoreductase. A 13.7 kb insertion reduced the tocopherol and chlorophyll content, and the photosynthetic activity by repressing ZmPORB1 expression in embryos of NIL-K22, but did not affect the levels of the tocopherol precursors HGA(homogentisic acid)and PMP(phytyl monophosphate). Furthermore, ZmPORB1 is inducible by low oxygen and light, thereby involved in the hypoxia response in developing embryos. Concurrent with natural hypoxia in embryos, the redox state has been changed with NO increasing and H_(2)O_(2) decreasing, which lowered γ-tocopherol content via scavenging reactive nitrogen species. In conclusion, we proposed that the lower lightharvesting chlorophyll content weakened embryo photosynthesis, leading to fewer oxygen supplies and consequently diverse hypoxic responses including an elevated γ-tocopherol consumption. Our findings shed light on the mechanism for fine-tuning endogenous oxygen concentration in the maize embryo through a novel feedback pathway involving the light and low oxygen regulation of ZmPORB1 expression and chlorophyll content.

关键词： maize tocopherol hypoxia photosynthesis ZmPORB1

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高质量发展视角下对研究者发起的临床研究全过程管理的问题探讨

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中国新药与临床杂志 2024年第4期43卷 263-267页

作者：尹妍首都医科大学宣武医院科研处北京100053

研究者发起的临床研究(IIT)是临床研究的重要组成部分。本文结合北京某三甲医院IIT管理的工作实践,从临床研究组织管理架构设计、科学性审查和伦理审查要点、系统备案、IIT合同审核重点和项目质量控制等方面与国家卫生健康委员会出台的... 详细信息

研究者发起的临床研究(IIT)是临床研究的重要组成部分。本文结合北京某三甲医院IIT管理的工作实践,从临床研究组织管理架构设计、科学性审查和伦理审查要点、系统备案、IIT合同审核重点和项目质量控制等方面与国家卫生健康委员会出台的IIT管理办法逐一比照分析,并针对上述方面提出相应的优化对策,旨在为建立健全医疗机构内部组织管理体系,促进临床研究高质量发展。

关键词：临床研究质量控制全面质量管理组织和管理

高性能Ir基阳极双催化层阴离子交换膜电解水

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材料导报 2024年第6期38卷 1-7页

作者：尹燕尹硕尧陈斌冯英杰张俊锋天津大学机械工程学院先进内燃动力全国重点实验室天津300072 中国汽车技术研究中心有限责任公司移动源污染排放控制技术国家工程实验室天津300300 中石化(北京)化工研究院有限公司催化科学研究所北京100013

设计高性能低Ir阳极催化层对阴离子交换膜电解水(AEMWE)商业化发展至关重要。本研究采用催化剂涂覆基底(CCS)方法,构建基于氧化铱(IrO_(2))和碳载铱(IrC)双催化层的阳极结构,提出了一种新型双Ir催化层并提高了AEMWE性能。研究表明,在IrC... 详细信息

设计高性能低Ir阳极催化层对阴离子交换膜电解水(AEMWE)商业化发展至关重要。本研究采用催化剂涂覆基底(CCS)方法,构建基于氧化铱(IrO_(2))和碳载铱(IrC)双催化层的阳极结构,提出了一种新型双Ir催化层并提高了AEMWE性能。研究表明,在IrC-IrO_(2)(先喷涂碳载铱,后喷涂氧化铱)催化层中,IrC高度分散特性有利于提高催化层中Ir的利用率,优化了催化层内电子、氢氧根离子的传输。采用商业Pt/C催化剂作为阴极,IrC-IrO_(2)阳极双催化层组装成碱性膜电极,在1 mol/L KOH电解质条件下,2.0 V时IrC-IrO_(2)电极达到了2.31 A/cm^(2)的高电流密度,而且在低浓度电解质以及纯水中依旧保持较高的性能。本研究为碱性膜电解水技术高效催化层的设计提供了参考。

关键词：阴离子交换膜电解水(AEMWE) 析氧反应(OER) 双催化层 Ir基催化剂

新基建“三网融合”对制造业新质生产力的作用路径研究——基于资源错配的视角

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工业技术经济 2024年第9期43卷 44-54页

作者：赵丽尹妍新疆财经大学金融学院乌鲁木齐830012

在发展动能由生产要素驱动向效率驱动的转型期,能源、交通、信息三网融合形成了新质生产力发展的必要基础设施,为制造业转型升级提供了支撑。那么新基建三网融合如何影响制造业新质生产力发展呢?本文利用2012~2022年我国省级面板数据构... 详细信息

在发展动能由生产要素驱动向效率驱动的转型期,能源、交通、信息三网融合形成了新质生产力发展的必要基础设施,为制造业转型升级提供了支撑。那么新基建三网融合如何影响制造业新质生产力发展呢?本文利用2012~2022年我国省级面板数据构建双向固定效应模型进行实证分析,实证结果表明:新基建三网融合对制造业新质生产力的形成与发展具有激励效应,该正向影响可通过降低创新资源错配度、绿色资金错配度和人才资源错配度加以实现;并且新基建三网融合也能带动邻近地区制造业新质生产力的发展,即存在空间溢出效应;同时在进行异质性分析后发现,新基建三网融合对经济韧性较低、产业转型不足以及环境规制力度较强地区的制造业新质生产力水平影响更大。基于此,本文提出深入推进三网融合、促进创新资源协调配置、强化“绿色门槛”效应和推动人才链与新兴产业链“双链融合”的发展建议。

关键词：新基建三网融合资源配置新质生产力绿色门槛双链融合创新资源产业转型

Trial characteristics and treatment effect estimates in randomized controlled trials of Chinese herbal medicine: A meta-epidemiological study

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Journal of Integrative Medicine 2024年第3期22卷 223-234页

作者： Betty H.Wang Ya-li Lin yin-yan Gao Jin-lu Song Lang Qin Ling-qi Li Wen-qi Liu Claire C.W.Zhong Mary Y.Jiang Chen Mao Xiao-bo yang Vincent C.H.Chung Irene X.Y.Wu Jockey Club School of Public Health and Primary Care the Chinese University of Hong KongHong Kong 999077China Xiangya School of Public Health Central South UniversityChangsha 410006Hunan ProvinceChina School of Chinese Medicine the Chinese University of Hong KongHong Kong 999077China School of Public Health Southern Medical UniversityGuangzhou 510080Guangdong ProvinceChina State Key Laboratory of Dampness Syndrome of Chinese Medicine the Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Chinese Medicine Syndrome Research Team the Second Affiliated HospitalGuangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome Guangzhou 510120Guangdong ProvinceChina Hunan Provincial Key Laboratory of Clinical Epidemiology Central South UniversityChangsha 410006Hunan ProvinceChina

Background:Previously published meta-epidemiological studies focused on Western medicine have identified some trial characteristics that impact the treatment effect of randomized controlled trials(RCTs).Nevertheless,it remains unclear if similar associations exist in RCTs on Chinese herbal medicine(CHM).Further,Chinese medicine-related characteristics have not been explored ***:To investigate trial characteristics related to treatment effect estimates on CHM *** strategy:This meta-epidemiological study searched 5 databases for systematic reviews on CHM treatment published between January 2011 and July *** criteria:An eligible systematic review should only include RCTs of CHM and conduct at least one *** extraction and analysis:Two reviewers independently conducted data extraction on general characteristics of systematic reviews,meta-analyses and included *** also assessed the risk of bias of RCTs using the Cochrane risk of bias tool.A two-step approach was used for data *** ratio of odds ratios(ROR) and difference in standardized mean differences (dSMD) with 95%confidence interval (CI) were applied to present the difference in effect estimates for binary and continuous outcomes,***:Ninety-one systematic reviews,comprising 1338 RCTs were *** binary outcomes,RCTs incorporated with syndrome differentiation (ROR:1.23;95%CI:[1.07,1.39]),adopting Chinese medicine formula (ROR:1.19;95%CI:[1.03,1.34]),with low risk of bias on incomplete outcome data (ROR:1.29;95%CI:[1.06,1.52]) and selective outcome reporting (ROR:1.12;95%CI:[1.01,1.24]),as well as a trial size≥100 (ROR:1.23;95%CI:[1.04,1.42]) preferred to show larger effect *** for continuous outcomes,RCTs with Chinese medicine diagnostic criteria (dSMD:0.23;95%CI:[0.06,0.41]),judged as high/unclear risk of bias on allocation concealment (dSMD:-0.70;95%CI:[-0.99,-0.42]),with low risk of bias on incomplete outcome data (dSMD:0.30

关键词： Chinese herbal medicine Randomized controlled trial Risk of bias Meta-epidemiological study Effect estimates