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A Parametric Survey of the CME Triggering Process by Numerical Simulations

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Chinese Journal of Astronomy and Astrophysics 2005年第6期5卷 636-644页

作者： xiao-yan Xu peng-Fei Chen Cheng Fang Department of Astronomy Nanjing University Nanjing 210093

Observations indicate that solar coronal mass ejections （CMEs） are closely associated with reconnection-favored flux emergence, which was explained in the emerging flux trigger mechanism for CMEs by Chen ＆ Shibata based on numerical simulations. We present a parametric survey of the triggering agent： its polarity orientation, position, and the amount of the unsigned flux. The results suggest that whether a CME can be triggered depends on both the amount and location of the emerging flux, in addition to its polarity orientation. A diagram is presented to show the eruption and non-eruption regimes in the parameter space. The work is aimed at providing useful information for the space weather forecast.

关键词： Sun coronal mass ejections (CMEs)-Sun filaments

Th lymphocyte subsets in patients with Vogt-KoyanagiHarada disease

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International Journal of Ophthalmology(English edition) 2019年第2期12卷 207-211页

作者： Liang Liang xiao-yan peng Hong Wang The First Affiliated Hospital of Chongqing Medical University Chongqing Key Laboratory of Ophthalmology and Chongqing Eye Institute Beijing Tongren Eye Center Beijing Key Laboratory of Ophthalmology and Visual Science Beijing Tongren HospitalCapital Medical University

AIM: To assess helper T(Th) lymphocyte subset balance in patients with Vogt-Koyanagi-Harada(VKH) disease. METHODS: Sixty-eight active VKH patients and seventytwo inactive VKH patients were included in this study. One hundred healthy individuals served as controls. Peripheral blood was obtained from VKH patients and healthy controls. Th lymphocyte subsets were analyzed by flow cytometry. Plasma concentration of interleukin(IL)-17, IL-10, transforming growth factor(TGF)-β, IL-23 and IL-6 was examined by enzyme-linked immunosorbent assay(ELISA). RESULTS: VKH patients with active uveitis had significantly higher percentages of both Th1 and Th17 cells and lower percentages of regulatory T(Treg) cells as compared with inactive VKH patients and healthy controls. Th1/Th2 and Th17/Treg ratios were also significantly elevated in active VKH patients. The percentages of Th1, Th17 and Treg cells and the Th1/Th2, Th17/Treg ratio did not differ between inactive VKH patients and healthy controls. There was no difference concerning the percentage of Th2 cells among all the groups. VKH patients with active uveitis showed an elevated level of peripheral Th17 related cytokines levels(TGF-β, IL-6, IL-23, and IL-17) and a decreased level of Treg related cytokines(IL-10) compared with inactive VKH patients and healthy controls. Inactive VKH patients showed no differences in peripheral Th17 related cytokines(TGF-β, IL-6, IL-23, and IL-17) and Treg related cytokines(IL-10) levels compared with healthy controls. CONCLUSION: Th1 and Th17 cells are significantly increased and Treg cells significantly decreased in active VKH compared with inactive VKH or healthy controls. Therefore, Th lymphocyte subset analysis may serve as a disease biomarker for VKH.

关键词： Vogt-Koyanagi-Harada disease Th lymphocyte Th17 cell Treg cell cytokines

Macular ganglion cell complex injury in different stages of anterior ischemic optic neuropathy

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World Journal of Clinical Cases 2021年第21期9卷 5830-5839页

作者： Wei Zhang Xin-Quan Sun xiao-yan peng Beijing Tongren Eye Hospital Capital Medical UniversityBeijing 100730China Beijing Aier Intech Eye Hospital Beijing 100021China China-Japanese Friendship Hospital Beijing 100029China

BACKGROUND Anterior ischemic optic neuropathy(AION)is a group of ophthalmic diseases in which the optic nerve is injured causing ***,the pathogenesis,clinical manifestations,and clinical treatments of AION are yet *** a few related experimental or clinical reports are available on the *** this study,spectral domain optical coherence tomography(SD-OCT)was used to examine the morphology of thickness swelling and atrophic changes of macular ganglion cell complex(mGCC)in the different stages of AION that were then compared with the visual ***,the clinical value of mGCC examination was alleged to be similar to that of the visual *** To explore the mGCC injury at different stages in AION and the clinical *** Cases with AION were analyzed in a retrospective ***-OCT was used to analyze the correlation between mGCC and peripapillary retinal nerve fiber layer thicknesses at different stages of AION and the changes in the corresponding stages of visual *** A total of 21 cases(28 eyes)presented *** onset time of AION was defined as early stage(within 3 wk of onset),middle stage(from 3 wk to 2 mo),and late stage(disease span>2 mo).In the early stage,the mGCC thickness of SD-OCT was within the normal high limit,and the perioptic nerve fibers thickness was more than the *** changes in the visual field in early stage were not consistent with the swelling changes in mGCC and peri-disc nerve *** addition,atrophy and thinning appeared in mGCC,and the perioptic nerve fibers were ***,the thickness was lower in the middle period than that in the early *** change in visual field was consistent with that of mGCC in this *** the late stage,mGCC shrank and thinned,and the thickness of the nerve fibers around the optic disc in the corresponding region shrank and *** The changes in mGCC thickness in patients with AION showed early,middle,and late stages of devel

关键词： Anterior ischemic optic neuropathy Macular ganglion cell complex Visual field Spectral domain optical coherence tomography Eyes

Radar emitter multi-label recognition based on residual network

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Defence Technology（防务技术） 2022年第3期18卷 410-417页

作者： Yu Hong-hai yan xiao-peng Liu Shao-kun Li Ping Hao Xin-hong Science and Technology on Electromechanical Dynamic Control Laboratory School of Mechatronical EngineeringBeijing Institute of TechnologyBeijing100081China Beijing Institute of Telemetry Technology Beijing100081China

In low signal-to-noise ratio(SNR)environments,the traditional radar emitter recognition(RER)method struggles to recognize multiple radar emitter signals in *** paper proposes a multi-label classification and recognition method for multiple radar-emitter modulation types based on a residual *** method can quickly perform parallel classification and recognition of multi-modulation radar time-domain aliasing signals under low ***,we perform time-frequency analysis on the received signal to extract the normalized time-frequency image through the short-time Fourier transform(STFT).The time-frequency distribution image is then denoised using a deep normalized convolutional neural network(DNCNN).Secondly,the multi-label classification and recognition model for multi-modulation radar emitter time-domain aliasing signals is established,and learning the characteristics of radar signal time-frequency distribution image dataset to achieve the purpose of training ***,time-frequency image is recognized and classified through the model,thus completing the automatic classification and recognition of the time-domain aliasing *** results show that the proposed method can classify and recognize radar emitter signals of different modulation types in parallel under low SNRs.

关键词： Radar emitter recognition Image processing Parallel Residual network Multi-label

Successively bilateral cytomegalovirus retinitis in immunocompromised patient with Good's syndrome

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International Journal of Ophthalmology(English edition) 2018年第12期11卷 2021-2023页

作者： Feng Hu Yuan Du xiao-yan peng Beijing Institute of Ophthalmology Beijing 100005China Beijing Tongren Eye Center Beijing Tongren Hospital Capital Medical UniversityBeijing 100730China

Dear Editor,I am Dr. Feng Hu, from the Department of Ophthalmology of Beijing Tongren Hospital, Beijing, China. I write to present a case report of cytomegalovirus retinitis (CMVR) in Good’s syndrome (GS).GS is an ex... 详细信息

关键词： In Successively bilateral cytomegalovirus retinitis in immunocompromised patient with Good’s syndrome Figure

BiAlO_(3)-modified BiFeO_(3)-BaTiO_(3) high Curie temperature lead-free piezoelectric ceramics with enhanced performance

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Rare Metals 2023年第11期42卷 3839-3850页

作者： xiao-xiao Zhou Yu-Cheng Tang He-Zhang Li Yi-Jin Hao Meng-Ping Xue Jun Pei xiao-yan peng Bo-Ping Zhang School of Materials Science and Engineering University of Science and Technology BeijingBeijing100083China Department of Precision Instrument Tsinghua UniversityBeijing10084China Beijing Key Laboratory of Special Ceramics and Refractories China Iron&Steel Research Institute GroupBeijing100081China

BiFeO_(3)-BaTiO_(3)(BF-BT)lead-free piezoelectric ceramics have high piezoelectricity and high Curie temperature(T_(C)),but the mixed-valence Fe ions and Bi^(3+)volatilization would promote the formation of Bi_(25)FeO_(40)/Bi_(2)Fe_(4)O_9 and oxygen vacancy,which greatly degrade the insulation properties required for *** this study,it was found that the modification of BiAlO_(3)(BA)in BF-BT ceramics could effectively solve these problems,reducing the leakage current to 1×10^(-9)A·cm^(-2)and transiting the space charge-limited conduction to ohmic *** of the enhanced insulation properties and appropriate rhombohedral-pseudocubic phase ratio(C_R/C_(PC)),BF-BT-xBA ceramics in an optimized composition obtain enhanced piezoelectric performance:piezoelectric charge coefficient(d_(33))=196 pC·N^(-1),planar electromechanical coupling coefficient(k_(p))=31.1%,T_(C)=487℃and depolarization temperature(T_d)=250°C;unipolar strain(S_(uni))=0.17%and piezoelectric strain coefficient(d_(33)^(*))=335 pm·V^(-1)at 100℃.Especially,d_(33)exceeds 283 pC·N^(-1)at 233℃and d_(33)^(*)is 335 pm·V^(-1)at100℃,showing an excellent high-temperature piezoelectricity and high depolarization *** results are attributed to the domain structure of rhombohedral-pseudocubic phase coexistence and its high-temperature switching *** work provides a feasible and effective approach to improve the high temperature piezoelectric properties of BF-BT-xBA ceramics,making them more suitable for high temperature applications.

关键词： BiFeO_(3)-BaTiO_(3)(BF-BT) Curie temperature Electrical insulation properties Piezoelectric properties Thermal stability

Effects of antiseizure medications on alternative psychosis and strategies for their application

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World Journal of Psychiatry 2022年第4期12卷 580-587页

作者： Yin yan Jun-Hong Wu xiao-yan peng Xue-Feng Wang Department of Neurology the First Affiliated Hospital of Chongqing Medical UniversityChongqing Key Laboratory of NeurologyChongqing 400016China

Forced normalization(FN)is a unique phenomenon that is often seen in the treatment of *** is characterized by abnormal mental behavior and disordered emotions in epilepsy patients despite a significantly improved electroencephalogram and successful seizure control;the occurrence of FN seriously affects patients’quality of *** causes of FN include antiseizure medications(ASMs),epilepsy surgery and vagus nerve stimulation,with ASMs being the most common ***,with the timely reduction or discontinuation of ASMs and the use of antipsychotic drugs,the overall prognosis is ***,we perform an extensive review of the literature pertaining to FN,including its epidemiology,possible mechanisms,clinical features,treatment and prognosis.

关键词： Forced normalization Antiseizure medications Neurotransmitter Antipsychotic drugs Electroshock

Clinical Study with Randomized Control on the Therapy of Integrated Chinese and Western Medicine in Treating Neurological Autoimmune Diseases:A Meta-Analysis

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World Journal of Traditional Chinese Medicine 2018年第3期4卷 85-95页

作者： xiao-yan peng Jin-Yun Ma xiao-Dong Cheng Institute of Clinical Immunology Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine

Objective: The main objective of this study is to evaluate the effects of integrated Chinese and Western medicine in the treatment of neurological autoimmune diseases. Materials and Methods: The literature was comprehensively searched to collect the randomized controlled trials about integrated Chinese and Western medicine in the treatment of neurological autoimmune diseases. Neurological autoimmune diseases mainly occur in the central nervous system(CNS) and peripheral nervous system. Therefore, multiple sclerosis(MS) was chosen as the representative in the CNS, and Guillain–Barre syndrome(GBS) was chosen as the representative in the peripheral nervous system. Extended Disability Status Scale(EDSS) score, effective rate, clinical symptom score, neurological functional sign score, recurrence frequency, and incidence rate of adverse reactions were chosen as the markers of outcome variables of MS, and the effective rate and Hughes score were also chosen as the markers of outcome variables of GBS. Results: For MS, the results showed that there was a significant difference in statistical analysis between the experimental group and the control group in EDSS score, the effective rate, and the recurrence frequency. However, through the comparison of clinical symptom score, neurological functional sign score, and incidence rate of adverse reaction of both two groups, the results showed that there was no significant difference in the statistical analysis. For GBS, through the comparison of effective rate and Hughes score of both two groups, the results showed that there was a significant difference in statistical analysis. Conclusions: The study demonstrated that compared with Western medicine, the therapy of integrated Chinese and Western medicine was more effective in treating neurological autoimmune diseases.

关键词： Guillain-Barre syndrome integrated Chinese and Western medicine meta-analysis multiple sclerosis randomized controlled trial

Effect of femtosecond and microkeratome flaps creation on the cornea biomechanics during laser in situ keratomileusis： one year follow-up

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International Journal of Ophthalmology(English edition) 2016年第10期9卷 1409-1414页

作者： Qian Sun Zheng-Zheng Deng Yue-Hua Zhou Jing Zhang xiao-yan peng Ophthalmic Center Beijing Tongren Hospital Capital Medical University Beijing Ophthalmology & Visual Sciences Key Lab Beijing 100730 China Mingren Hospital Handan 05000 Hebei Province China

AIM： To compare the corneal biomechanical outcomes at one year after laser in situ keratomileusis（LASIK） with the flaps created by Ziemer and Moria M2 microkeratome with 110 head and -20 ***： Totally 100 eyes of 50 consecutive patients were enrolled in this prospective study and divided into two groups for corneal flaps created by Ziemer Femto LDV and Moria M2 microkeratome with 110 head and -20 *** biomechanical properties including cornea resistance factor（CRF） and cornea hysteresis（CH） were measured before and 1,3,6,12 mo after surgery by ocular response *** cornea thickness and corneal flap thickness were measured by optical coherence ***： The ablation depth（P=0.693）,residual corneal thickness（P=0.453）,and postoperative corneal curvature（P=0.264） were not significant different between Ziemer group and Moria 110-20 group after *** residual stromal bed thickness,corneal flap thickness,CH and CRF at 12 mo after surgery were significant different between Ziemer group and Moria 110-20 group（P〈0.01）; Ziemer group gained better corneal biomechanical *** CRF and CH increased gradually from 1 to12 mo after surgery in Ziemer group,increased from 1 to 6 mo but decreased from 6 to 12 mo in Moria 110-20 *** CRF and CH at one year after surgery increased with the increasing of residual cornea thickness; pre-LASIK CRF,CRF also increased with residual stromal bed thickness,while CH decreased with the increasing of pre-LASIK intraocular pressure and cornea flap thickness（P〈0.01）.CONCLUSION： In one year follow-up,femtosecond laser can provide better cornea flaps with stable cornea biomechanics than mechanical microkeratome.

关键词： femtosecond microkeratome biomechanics keratomileusis