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Storylines of family medicine Ⅱ:foundational building blocks—context,community and health

Family Medicine and Community Health 2024年第S3期12卷 12-22页

作者： William B Ventres Leslie A Stone Rupal Shah Tamala Carter Geoffrey M Gusoff Winston Liaw Bich-May Nguyen Joanna V Rachelson Mary Alice Scott Teresa L Schiff-Elfalan Seiji yamada Robert C Like Kathleen Zoppi A Peter Catinella Richard M Frankel Shailendra Prasad Family and Preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Bridge Lane Group Practice LondonUK Penn Center for Community Health Workers University of PennsylvaniaPhiladelphiaPennsylvaniaUSA National Clinician Scholars Program UCLA David Geffen School of MedicineLos AngelesCaliforniaUSA Health Systems and Population Health Sciences University of Houston Tilman J Fertitta Family College of MedicineHoustonTexasUSA Southern New Mexico Family Medicine Residency Program Las CrucesNew MexicoUSA New Mexico Primary Care Training Program Silver CityNew MexicoUSA Anthropology New Mexico State UniversityLas CrucesNew MexicoUSA Family Medicine and Community Health University of Hawai'i at Manoa John A Burns School of MedicineHonoluluHawaiiUSA Family Medicine and Community Health Rutgers Robert Wood Johnson Medical SchoolNew BrunswickNew JerseyUSA Family Medicine Indiana University School of MedicineIndianapolisIndianaUSA Family Medicine–Transmountain Texas Tech University Health Sciences CenterEl PasoTexasUSA Medicine Indiana University School of MedicineIndianapolisIndianaUSA Family Medicine and Community Health University of Minnesota Medical School-Twin Cities CampusMinneapolisMinnesotaUSA

Storylines of Family Medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine,as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅱ:foundational building blocks—context,community and health’,authors address the following themes:‘Context—grounding family medicine in time,place and being’,‘Recentring community’,‘Community-oriented primary care’,‘Embeddedness in practice’,‘The meaning of health’,‘Disease,illness and sickness—core concepts’,‘The biopsychosocial model’,‘The biopsychosocial approach’and‘Family medicine as social medicine.’May readers grasp new implications for medical education and practice in these essays.

关键词： thematic illustration dimensions

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An Inverse Laplace Transform on Lattice Spacing

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Chinese Physics Letters 2013年第3期30卷 32-35页

作者： Hirofumi yamada Division of Mathematics and Science Chiba Institute of TechnologyShibazono 2-1-1NarashinoChiba 275-0023Japan

An inverse Laplace transform on lattice spacing is introduced as a computational framework of the extrapolation of the strong coupling expansion to the scaling *** apply the transform to the two-dimensional nonlinear O(N)model at N≥3 and show that the approximation of the continuum limit of the susceptibility agrees with the existing theoretical and Monte Carlo data.

关键词： apply spacing susceptibility

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Self-calibration and Compensation of Setting Errors for Surface Profile Measurement of a Microstructured Roll Workpiece

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Chinese Journal of Mechanical Engineering 2014年第1期27卷 14-22页

作者： GAO Wei XU Bin TAKEISHI toshiki SHIMIZU Yuki ITO So Department of Nanomechanics Tohoku University School of Manufacturing Science and Engineering Sichuan University

Microstructured roll workpieces have been widely used as functional components in the precision industries. Current researches on quality control have focused on surface profile measurement of microstructured roll workpieces, and types of measurement systems and measurement methods have been developed. However, low measurement efficiency and low measurement accuracy caused by setting errors are the common disadvantages for surface profile measurement of microstructured roll workpieces. In order to shorten the measurement time and enhance the measurement accuracy, a method for self-calibration and compensation of setting errors is proposed for surface profile measurement of microstructured roll workpieces. A measurement system is constructed for the measurement, in which a precision spindle is employed to rotate the roll workpiece and an air-bearing displacement sensor with a micro-stylus probe is employed to scan the microstructured surface of the roll workpiece. The resolution of the displacement sensor is 0.14 nm and that of the rotary encoder of the spindle was 0.15r~. Geometrical and mathematical models are established for analyzing the influences of the setting errors of the roll workpiece and the displacement sensor with respect to the axis of the spindle, including the eccentric error of the roll workpiece, the offset error of the sensor axis and the zero point error of the sensor output. Measurement experiments are carded out on a roll workpiece on which periodic microstructures are a period of 133 i^m along the circumferential direction. Experimental results demonstrate the feasibility of the self-compensation method. The proposed method can be used to detect and compensate the setting errors without using any additional accurate artifact.

关键词： measurement profile setting error self-calibration compensation microstructure roll workpiece

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Late-onset non-islet cell tumor hypoglycemia: A case report

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World Journal of Clinical Cases 2021年第1期9卷 163-169页

作者： Shunichi Matsumoto Eijiro yamada Yasuyo Nakajima Naoki Yamaguchi Takashi Okamura toshiki Yajima Satoshi Yoshino Kazuhiko Horiguchi Emi Ishida Masashi Yoshikawa Jun Nagaoka Sho Sekiguchi Mai Sue Shuichi Okada Izumi Fukuda Ken Shirabe Masanobu yamada Department of Medicine and Molecular Science Gunma University Graduate School of MedicineMaebashi 371-8511GunmaJapan Division of General Thoracic Surgery Integrative Center of General SurgeryGunma University HospitalMaebashi 371-8511GunmaJapan Department of Endocrinology Diabetes and MetabolismGraduate School of Medicine Nippon Medical SchoolTokyo 1138602Japan

BACKGROUND Hypoglycemia due to non-insulin-producing tumors is referred to as non-islet cell tumor hypoglycemia(NICTH).As NICTH is a rare lesion,the natural course of NICTH is not well *** report a case of NICTH that was observed 30 years before the onset of *** SUMMARY A 50-year-old man was diagnosed with an abnormal right chest shadow during a routine X-ray examination,but no further examination was undertaken because the lesion appeared *** years after the tumor discovery,the patient was admitted to the hospital with symptoms of severe hypoglycemia,which was diagnosed as NICTH based on a complete *** tumor was resected and found to be a solitary fibrous mass(15.6 cm×13.7 cm×10.4 cm);thereafter,the patient’s blood glucose levels normalized and he completely *** NICTH can have an acute onset,even if the tumor has been present and asymptomatic over a long time period.

关键词： Hypoglycemia Non-islet cell tumor hypoglycemia Blood glucose Solitary tumor Late onset Case report Insulin-like growth factor II

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Analysis of shopping behavior characteristics in the Keihanshin metropolitan area in Japan based on a person trip survey

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Geo-Spatial Information Science 2020年第4期23卷 305-315页

作者： Takashi yamada Takumi Hayashida Department of Human Factors Engineering and Environmental Design Faculty of Biology-Oriented Science and TechnologyKindai UniversityKinokawaWakayamaJapan

This study analyzed weekday shopping behavior from a home base to a destination using data from the 4th Keihanshin metropolitan area person trip *** first analyzed the relationships between occupation and transportation means,transportation means and travel time,and transportation means and duration of time at the *** of a chi-square test,residual analysis,and correspondence analysis confirmed that employed persons tend to travel by cars while unemployed persons tend to travel by bus or *** relationship between travel time and duration of time at the destination was also revealed according to transportation *** of a cluster analysis then classified shopping behaviors to expose four ***,multiple regression analyzed the degree to which certain variables were related to duration of time at the *** confirmed a strong relationship between duration of time at the destination and travel *** degree of this factor’s influence on other variables was also *** value of these findings is that the relationship between travel time by means of transportation and the duration of time at the destination was clarified using statistical *** then found a highly accurate equation that estimates the duration of time at a destination from the travel *** the duration of time at a destination can be estimated,it may be possible to more accurately develop the structure of rest facilities,the number of parking lots,the degree of congestion,and so on,which can be associated with the customer’s usage behavior in a shopping *** research in this paper contributes to the field of urban analysis and marketing by presenting a new effective method for person trip survey and analysis.

关键词： Person trip survey shopping behavior transportation means travel time duration of time at a destination

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Experimental Analysis of Flow Structure in Contra-Rotating Axial Flow Pump Designed with Different Rotational Speed Concept

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Journal of Thermal Science 2013年第4期22卷 345-351页

作者： Linlin Cao Satoshi Watanabe toshiki Imanishi Hiroaki Yoshimura Akinori Furukawa Graduate School of Engineering Kyushu University Department of Mechanical Engineering Kyushu University Oita National College of Technology

As a high specific speed pump, the contra-rotating axial flow pump distinguishes itself in a rear rotor rotating in the opposite direction of the front rotor, which remarkably contributes to the energy conversion, the reduction of the pump size, better hydraulic and cavitation performances. However, with two rotors rotating reversely, the significant interaction between blade rows was observed in our prototype contra-rotating rotors, which highly affected the pump performance compared with the conventional axial flow pumps. Consequently, a new type of rear rotor was designed by the rotational speed optimization methodology with some additional considerations, aiming at better cavitation performance, the reduction of blade rows interaction and the secondary flow suppression. The new rear rotor showed a satisfactory performance at the design flow rate but an unfavorable positive slope of the head - flow rate curve in the partial flow rate range less than 40% of the design flow rate, which should be avoided for the reliability of pump-pipe systems. In the present research, to understand the internal flow field of new rear rotor and its relation to the performances at the partial flow rates, the velocity distributions at the inlets and outlets of the rotors are firstly investigated. Then, the boundary layer flows on rotor surfaces, which clearly reflect the secondary flow inside the rotors, are analyzed through the limiting streamline observations using the multi-color oil-film method. Finally, the unsteady numerical simulations are carded out to understand the complicated internal flow structures in the rotors.

关键词： Contra-rotating rotors Internal flow Limiting streamlines Tip leakage vortex Corner separation

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Supra-angular biopsy is more reliable for atrophy recognization:analysis of 1598 cases for gastric mucosal histological examination

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World Journal of Gastroenterology 2000年第6期6卷 893-897页

作者： Nobutaka yamada Department of Pathology First Hospital of Nippon Medical SchoolTokyoJapan

INTRODUCTIONChronic gastritis might be a disease of the highestmorbidity in the *** Warren and Marshallsuccessfully isolated and cultured Helicobacter pylori(***)from a gastric antrum biopsy,intensive researches produ... 详细信息

关键词： Helicobacter pylori gastric mucosa/pathology biopsy gastroscopy gastritis atrophic/pathology metaplasia

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Multi-Terabit Long-Haul Transmission System Utilizing Distributed Raman Amplification Technologies

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光学学报 2003年第S1期23卷 567-568页

作者： Takao Naito toshiki Tanaka Fujitsu Laboratories Ltd. 4-1-1 Kamikodanaka Nakahara-ku Kawasaki 211-8588 JapanFujitsu Laboratories Ltd. 4-1-1 Kamikodanaka Nakahara-ku Kawasaki 211-8588 Japan

Here we summarize multi-terabit long-haul transmission experiment and distributed Raman amplification (DRA) technologies. As well, we investigate the configuration of dispersion-managed fibers for the DRA-based system... 详细信息

关键词： EDFA for very it as of WDM DRA Multi-Terabit Long-Haul Transmission System Utilizing Distributed Raman Amplification Technologies OSNR

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Liquid biopsy leads to a paradigm shift in the treatment of pancreatic cancer

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World Journal of Gastroenterology 2022年第46期28卷 6478-6496页

作者： Fumiaki Watanabe Koichi Suzuki Hiroshi Noda toshiki Rikiyama Department of Surgery Saitama Medical CenterJichi Medical UniversitySaitama 330-8503Japan

Pancreatic ductal adenocarcinoma(PDAC)is one of the most *** 5-year survival rate is very *** recent induction of neoadjuvant chemotherapy and improvements in chemotherapy for patients with pancreatic cancer have resulted in improved survival ***,the prognosis of pancreatic cancer is still *** dramatically improve the prognosis,we need to develop more tools for early diagnosis,treatment selection,disease monitoring,and response rate ***,liquid biopsy(circulating free DNA,circulating tumor DNA,circulating tumor cells,exosomes,and microRNAs)has caught the attention of many researchers as a new biomarker that is minimally invasive,confers low-risk,and displays an overall state of the ***,liquid biopsy does not employ the traditional difficulties of obtaining tumor samples from patients with advanced PDAC to investigate their molecular biological *** addition,it allows for long-term monitoring of the molecular profile of tumor *** could help in identifying tumor-specific alterations that use the target structure for tailor-made *** this review,we highlighted the latest discoveries and advances in liquid biopsy technology in pancreatic cancer research and showed how it can be applied in clinical practice.

关键词： Pancreatic cancer Cell-free DNA Circulating tumor DNA Circulating tumor cells Exosomes MicroRNAs

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Molecular biomarkers for the detection of metastatic colorectal cancer cells

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World Journal of Gastroenterology 2014年第27期20卷 8928-8938页

作者： Hidenori Kamiyama Hiroshi Noda Fumio Konishi toshiki Rikiyama Department of Surgery Saitama Medical Center Jichi Medical University Department of Surgery Chichibu Municipal Hospital

Approximately half of all patients with colorectal cancer develop local recurrence or distant metastasis during the course of their illness. Recently, the molecular detection of metastatic cancer cells in various types of clinical samples, such as lymph nodes, bone marrow, peripheral blood, and peritoneal lavage fluid, has been investigated as a potential prognostic marker. The prognostic value of molecular tumor cell detection was independent of the type of detection method used. As assays become more sensitive and quantitative, a more thorough assessment of the cancer status of patients will be based on molecular markers alone. At present, it is difficult to conclude that one specific molecular marker is superior to others. Comparative analyses are recommended to assess the prognostic impact of molecular analyses in the same patient and determine the biomarkers that provide the most accurate prognostic information.

关键词： Molecular biomarker Metastatic colorectal cancer cell Circulating tumor cell Disseminated tumor cell Peritoneal lavage fluid Colorectal cancer

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