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Safety of an improved patent ductus arteriosus occluder for transcatheter closure of perimembranous ventricular septal defects with abnormally attached tricuspid chordae tendineae

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World Journal of Clinical Cases 2019年第5期7卷 562-571页

作者： Lu He ya-juan du Ge-Sheng Cheng Yu-Shun Zhang Department of Structural Heart Disease Xi'an Jiaotong University Medical College First Affiliated Hospital

BACKGROUND The off-label use of various devices has been reported for the transcatheter closure of perimembranous ventricular septal defects(PmVSD) because of serious complications, such as heart block and tricuspid regurgitation(TR),associated with conventional ventricular septal defect devices. However, whether certain defects such as PmVSD with abnormally attached tricuspid are fit for interventional treatment is still *** To explore the feasibility and safety of transcatheter closure of PmVSD with abnormally attached tricuspid chordae tendineae using an improved patent ductus arteriosus(PDA) *** We retrospectively analyzed 20 patients diagnosed with PmVSD with abnormally attached tricuspid chordae tendineae who underwent interventional treatment using an improved PDA occluder at our center from January 2012 to January 2016. Baseline characteristics and procedural and follow-up data were *** All 20 patients achieved procedure success. No heart block occurred during the operation. One patient had a transient complete right bundle branch block within48 h post-procedure and reverted to normal rhythm after intravenous injections of dexamethasone for 3 d. For all 20 patients, no residual shunt was observed by transthoracic echocardiography post-procedure. during the average follow-up period of 2.4 years, no severe TR was *** Using of the improved PDA occluder for the transcatheter closure of PmVSD with abnormally attached tricuspid chordae tendineae is a safe and promising treatment option. However, long-term follow-up in a large group of patients is still warranted.

关键词： Ventricular septal defect Transcatheter Patent ductus arteriosus occlude Tricuspid regurgitation Chordae tendineae

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Clinical relevance of atrial septal aneurysm and patent foramen ovale with migraine

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World Journal of Clinical Cases 2018年第15期6卷 916-921页

作者： Lu He Ge-Sheng Cheng ya-juan du Yu-Shun Zhang Department of Structural Heart Disease Xi'an Jiaotong University Medical College First Affiliated Hospital

AIM To test the potential association between atrial septal aneurysm(ASA) and migraine in patent foramen ovale(PFO) closure patients through an observational, singlecenter, case-controlled *** We studied a total of 450 migraineurs who had rightto-left shunts and underwent PFO closure in a retrospective single-center non-randomized registry from February 2012 to October 2016 on the condition that they were aged 18-45 years old. Migraine was diagnosed according to the International Classification of Headache Disorders, 3^(rd) edition and evaluated using the Headache Impact Test-6(HIT-6). All patients underwent preoperative transesophageal echocardiography, contrast transthoracic echocardiography, and computed tomography or magnetic resonance imaging examinations, with subsequent fluoroscopy-guided PFO closure. Based on whether they have ASA or not, the patients were divided into two groups: A(PFO with ASA, n = 80) and B(PFO without ASA, n = 370). Baseline characteristics and procedural and follow-up data were reviewed. RESULTS Compared to group B, group A had an increased frequency of ischemic lesions(11.3% vs 6.2%, P = 0.038) and migraine with aura(32.5% vs 21.1%, P = 0.040). The PFO size was significantly larger in group A(P = 0.007). There was no significant difference in HIT-6 scores between the two groups before and at the oneyear follow-up after the PFO closure [61(9) vs 63(9), P = 0.227; 36(13) vs 36(10), P = 0.706].CONCLUSION Despite its small sample size, our study suggests that the prevalence of ASA in PFO with migraine patients is associated with ischemic stroke, larger PFO size, and migraine with aura.

关键词： Patent foramen ovale Migraine Atrial septal aneurysm Contrast transthoracic echocardiography Right-to-left shunt Transesophageal echocardiography

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Journal of Geriatric Cardiology 2019年第6期16卷 490-494页

作者： Lu HE ya-juan du Ge-Sheng CHENG Yu-Shun ZHANG Department of Structural Heart Disease the First Affiliated Hospital of Xi’an Jiaotong University

An atrial septal defect (ASD) may cause right heart dysfunction, pulmonary hypertension and atrial fibrillation (AF), and atrial septal defect occlusion (ASDO) is the first choice for treating secundum defects when the morphology permits. ASD and AF frequently coexist, and the risk of AF and stroke persists after ASDO.[1] In recent years, left atrial appendage occlusion (LAAO) has been recognized as an effective treatment for stroke prevention in nonvalvular AF patients with a high risk of stroke, systemic embolism and bleeding who are unwilling to take oral anticoagulants or cannot tolerate them.

关键词： Anticoagulation Atrial septal defect Closure Device-related thrombosis Left atrial appendage

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Platypnea-orthodeoxia syndrome in a patient with a pre-existing patent foramen ovale successfully treated with an atrial septal occluder

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Journal of Geriatric Cardiology 2015年第3期12卷 323-325页

作者： Ting-Ting ZHANG Ge-Sheng CHENG Jun WANG Xing-Ye WANG Xue-Gang XIE ya-juan du Yu-Shun ZHANG The Second Department of Cardiology First Hospital Affiliated to Xi'an Jiaotong University Xi 'an Shaarzri Province China

Platypnea orthodeoxia syndrome is associated with dyspnea and arterial oxygen desamration accentuated by an upright posture. It can be secondary to an intracardiac shunt. We report a case of platypnea-orthodeoxia syndrome （POS） in a 58-year old male patient who had a pre-existing patent foramen ovale （PFO） and substantial pulmonary pathologies. He was successfully treated by percutaneous transcatheter closure of the PFO. Our case highlights the importance of recognition of this rare syndrome in patients who present with unexplained hy- poxia for whom transcatheter closure of the interatrial shunt can be safely carded out.

关键词： Intracardiac shunt Platypnea-orthodeoxia syndrome Patent foramen ovale Transcatheter closure

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糖化血红蛋白检测在妊娠期糖尿病诊断中的应用价值

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临床医学研究与实践 2017年第22期2卷 129-130页

作者：马亚娟杜清丽杨彩萍陕西省宝鸡市扶风县人民医院检验科陕西宝鸡722200 陕西省宝鸡市扶风县人民医院妇产科陕西宝鸡722200

目的探讨糖化血红蛋白(HbA1c)检测在妊娠期糖尿病(GDM)诊断中的价值。方法选取我院2013年1月至2016年5月收治的妊娠期糖尿病孕妇30例(GDM组),糖耐量正常孕妇52例(NGT组)和糖耐量减低孕妇28例(GIGT组)为研究对象。比较三组的糖化血红蛋白... 详细信息

目的探讨糖化血红蛋白(HbA1c)检测在妊娠期糖尿病(GDM)诊断中的价值。方法选取我院2013年1月至2016年5月收治的妊娠期糖尿病孕妇30例(GDM组),糖耐量正常孕妇52例(NGT组)和糖耐量减低孕妇28例(GIGT组)为研究对象。比较三组的糖化血红蛋白(HbA1c)、空腹血糖(FPG)、口服糖负荷试验的1 h切点血糖(OGCT-1 h PG)。结果 GDM组的HbA1c、FPG、OGCT-1 h PG水平和阳性率与NGT组和GIGT组比较,差异具有统计学意义(P0.05)。GDM组的HbA1c阳性率显著高于FPG阳性率(P0.05)。结论 HbA1c水平在GDM患者中明显升高,对早期诊断GDM具有重要意义。

关键词：妊娠期糖尿病糖化血红蛋白空腹血糖口服糖负荷实验

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Age and mean platelet volume-based nomogram for predicting the therapeutic efficacy of metoprolol in Chinese pediatric patients with vasovagal syncope

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World Journal of Pediatrics 2024年第9期20卷 957-965页

作者： Xiao-juan du ya-Qian Huang Xue-Ying Li Ying Liao Hong-Fang Jin Jun-Bao du Department of Pediatrics Peking University First HospitalNo.1 Xi’anmen StreetWest DistrictBeijing100034China State Key Laboratory of Vascular Homeostasis and Remodeling Peking UniversityNo.38Xueyuan RoadHaidian DistrictBeijing100191China Department of Statistics Peking University First HospitalBeijing100034China

Background Vasovagal syncope(VVS)is the most common type of orthostatic intolerance in *** investigated whether platelet-related factors related to treatment efficacy in children suffering from VVS treated with *** Metoprolol-treated VVS patients were *** median duration of therapy was three *** were followed and divided into two groups,treament-effective group and treatment-ineffective *** and least absolute shrinkage selection operator regressions were used to examine treatment outcome ***-operating characteristic(ROC)curves,precision-recall(PR)curves,calibration plots,and decision curve analyses were used to evaluate the nomogram *** Among the 72 patients who complete the follow-up,treatment-effective group and treatment-ineffective group included 42(58.3%)and 30(41.7%)cases,*** patients in the treatment-effective group exhibited higher mean platelet volume(MPV)[(11.0±1.0)fl vs.(9.8±1.0)fl,P<0.01]and platelet distribution width[12.7%(12.3%,14.3%)vs.11.3%(10.2%,12.2%),P<0.01]than those in the treatment-ineffective *** sex ratio was significantly different(P=0.046).A fit model comprising age[odds ratio(OR)=0.766,95%confidence interval(CI)=0.594-0.987]and MPV(OR=5.613,95%CI=2.297-13.711)might predict therapeutic *** area under the curve of the ROC and PR curves was computed to be 0.85 and 0.9,*** P value of the Hosmer-Lemeshow test was *** decision curve analysis confirmed that managing children with VVS based on the predictive model led to a net advantage ranging from 0.01 to *** nomogram is convenient for clinical *** A novel nomogram based on age and MPV can predict the therapeutic benefits of metoprolol in children with VVS.

关键词： Metoprolol Nomogram Retrospective study Therapeutic effect Vasovagal syncope

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Optimal livelihood strategy for different poverty groups among farmers: a case study of the Qin-Ba Mountain area in South-Shaanxi, China

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Journal of Mountain Science 2020年第5期17卷 1206-1220页

作者： SU Fang YIN ya-juan School of Economics and Management Shaanxi University of Science&TechnologyXi'an 710021China

Achieving sustainable livelihood is the ultimate goal of poverty alleviation efforts in mountainous areas,and selecting an optimal livelihood strategy for different poverty-type farmers greatly improves farmers’livelihood capital,resists livelihood risks,and promotes sustainable *** farmers,optimal livelihood strategy means better employment opportunities,higher family income(or better income structure),and stronger employability or development *** paper classifies different types of farmers’poverty on the basis of a quantitative evaluation of farmers’livelihood capital in the Qin-ba Mountain Area in South-Shaanxi by using the k-means clustering method and subsequently the fuzzy evaluation method to evaluate the effectiveness of farmers’livelihood ***,the multi-attribute decision-making model is used to analyze the selection of optimal livelihood strategies for different poverty-type *** results suggest a significant difference in the selection of the optimal livelihood strategy for different poverty-type *** without financial and human capital choose to"go out to work,"farmers lacking natural capital choose to"acquire social insurance and government relief,"farmers without physical capital choose to"use loans,"and farmers lacking social capital choose to"use savings."Studying the selection of optimal livelihood strategies for different poverty-type farmers can help to propose targeted sustainable livelihood optimization programs for farmers and accelerate efforts to overcome poverty in mountainous areas.

关键词： Optimal strategy Livelihood capital Effectiveness evaluation Qin-Ba Mountain Area Shaanxi

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Self-assembly Behavior of Rod-Coil-Rod Triblock Copolymers within a Planar Slit

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Chinese Journal of Polymer Science 2016年第7期34卷 838-849页

作者： ya-juan su 黄建花 Department of Chemistry Zhejiang Sci-Tech University Hangzhou 310018 China

The self-assembly behavior of sphere-forming R_5C_（30）R_5 triblock copolymers within a planar slit is studied by performing dissipative particle dynamics simulations. A sequence of novel structures which are not observed in bulk are formed within slits, including wetting layers, island-like structure, parallel cylinders, perpendicular cylinders and crosscylindrical structures. Perpendicular cylinders are always formed before the increase in the layers of parallel cylinders. A phase diagram of the assembled structures with respective to the slit property and height is thus presented. The rod length is found to have a significant impact on the rod alignment, and a disordered-ordered transition of rod orientation occurs with an increase in the length of rod blocks. Some special structures, such as parallel half-cylinders and arrowhead-shaped morphology, are observed when the rod length increases to a certain extent. Our results show that the property and height of the slit and rod length all influence the self-assembly of rod-coil-rod triblock copolymers.

关键词： Self-assembly Triblock copolymers Slit Simulation

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Analysis of RF Feedback Chain Isolation in Wireless Co-Time Co-Frequency Full duplex

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Journal of Electronic Science and Technology 2018年第3期16卷 280-286页

作者： juan Zhou Ying Shen ya-juan Xue Li Li the College of Communication Engineering Chengdu University of Information Technology the National Key Laboratory of Science and Technology on Communications University of Electronic Science and Technology of China

By employing a radio frequency(RF) feedback chain, the self-interference can be canceled efficiently in co-time co-frequency full duplex(CCFD). However, the evitable signal crosstalk which is caused by the imperfect RF feedback chain isolation usually damages the self-interference cancelation(SIC) performance. To deal with this problem, firstly, we analyze the impact of RF feedback chain isolation on SIC performance. Then a digital preprocessing scheme with RF feedback chain is proposed in the multiple-antenna CCFD architecture. Using both analytical and experimental methods, we find that the proposed scheme achieves a better performance on SIC.

关键词： Co-time co-frequency full duplex full duplex radio frequency feedback chain isolation radio frequency leakage signal self-interference cancellation

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Translating Solutions of the Nonparametric Mean Curvature Flow with Nonzero Neumann Boundary Data in Product Manifold M^(n)×R^(*)

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Chinese Annals of Mathematics,Series B 2022年第4期43卷 601-620页

作者： ya GAO Yi-juan GONG Jing MAO Faculty of Mathematics and Statistics Key Laboratory of Applied Mathematics of Hubei ProvinceHubei UniversityWuhan 430062China

In this paper,the authors can prove the existence of translating solutions to the nonparametric mean curvature flow with nonzero Neumann boundary data in a prescribed product manifold M^(n)×R,where M^(n) is an n-dime... 详细信息

关键词： Translating solutions Singularity Nonparametric mean curvature flow Convexity Ricci curvature

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